KEGG   Mycobacterium tuberculosis Haarlem/NITR202: I917_13740
Entry
I917_13740        CDS       T02654                                 
Name
(GenBank) 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II
  KO
K14652  3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
Organism
mtuh  Mycobacterium tuberculosis Haarlem/NITR202
Pathway
mtuh00740  Riboflavin metabolism
mtuh00790  Folate biosynthesis
mtuh01100  Metabolic pathways
mtuh01110  Biosynthesis of secondary metabolites
mtuh01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:mtuh00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00740 Riboflavin metabolism
    I917_13740
   00790 Folate biosynthesis
    I917_13740
Enzymes [BR:mtuh01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.25  GTP cyclohydrolase II
     I917_13740
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.99  Other carbon-carbon lyases
    4.1.99.12  3,4-dihydroxy-2-butanone-4-phosphate synthase
     I917_13740
SSDB
Motif
Pfam: DHBP_synthase GTP_cyclohydro2
Other DBs
NCBI-ProteinID: AGL23571
UniProt: R4M6K2
Position
2194633..2195697
AA seq 354 aa
MKTTDVRVRRAITAMAGGHAVVRAXADXNGDGYLVXAAQAATPRLVAFAVRHTSGYLRVA
LPGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPG
HVVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAV
EHGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDLGEHLAVIVGAV
GAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQACGX
FARGXAAXDVMPXTVTWILRDLGVYAIRLSDDVPGFGLVMFGAIREASTLAAAG
NT seq 1065 nt   +upstreamnt  +downstreamnt
atgaagacgaccgatgtgcgggtacgtcgtgcgatcacggcgatggcgggcggtcacgcc
gtggtccgtgcacsggcagaccscaatggmgatggctatctcgtctycgccgcccaggcc
gcgacgccgcggctggttgcctttgcggtccggcacacctcgggttatttgcgcgtcgcg
ctgccgggcgccgaatgcgagcgactgcacctgccgcccatgtgtgaccgagacaccacg
cattgcgtgtcggtcgacgttcgcggcaccggcaccggaatctcggcgagcgatcgcgcc
tggaccatcgcggcactggcttcggccacctccgtcgccgccgatttccaacgtccgggc
catgtggtgcccgtgcaggcgcaagccgacggtgtgctgggtcggcggggacccgccgag
gcggccgtcgacctggcccgcctggcggaacggcggccggccgccgcgctctgcgagatc
gtctcgcccgataatcccgtccagatggcgcaccacgccgagtcggtcgaattcgccgtc
gaacacggactggccatggtctcgatcggggagctggtggcgtatcgccggcggatcgag
ccccaggtggtccggtttacggcagcgacgctgcccacctgggccggcgcctcgcgtgtc
atcggctttcgtgacgtttacgacctcggcgagcatttggcggtcatcgtgggtgcggtc
ggtgccggggtgcccgtgccgctgcacgtccacatcgagtgcctgacgggcgacgtgttc
ggctcgacggcgtgccgctgcggcgaggaactcaacggcgcgctggcgaggatgtcggct
cagggcagcggcgtggtcttgtatctgcgtccgcccggacccgcgcaagcgtgcggcttk
ttcgcccggggcgrtgcggcgamcgatgtcatgccggwgaccgtgacatggatcctgcgc
gatcttggggtgtatgcgatccgactttccgatgatgtgccaggatttgggcttgtcatg
ttcggggcgatccgagaagccagcacgttggcggccgcaggttga

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