KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100592229
Entry
100592229         CDS       T03265                                 
Symbol
KDM6A
Name
(RefSeq) lysine-specific demethylase 6A isoform X2
  KO
K11447  lysine-specific demethylase 6A [EC:1.14.11.68]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:nle00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    100592229 (KDM6A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:nle03036]
    100592229 (KDM6A)
Enzymes [BR:nle01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.68  [histone H3]-trimethyl-L-lysine27 demethylase
     100592229 (KDM6A)
Chromosome and associated proteins [BR:nle03036]
 Eukaryotic type
  Histone modification proteins
   HMT complexes
    MLL3/MLL4 complex
     100592229 (KDM6A)
   Histone demethylases
    100592229 (KDM6A)
SSDB
Motif
Pfam: KDM6_C-hel JmjC TPR_1 KDM6_GATAL TPR_2 TPR_8 TPR_16 TPR_17 TPR_12 TPR_19 TPR_7 TPR_9 TPR_11 SNAP TPR_15 Glyco_hydro_120_ins ANAPC3
Other DBs
NCBI-GeneID: 100592229
NCBI-ProteinID: XP_003271073
Ensembl: ENSNLEG00000002537
UniProt: A0A2I3GAP5
Position
X:complement(46370851..46609079)
AA seq 1401 aa
MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPI
SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLQQPADENWDPTGTKKI
WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH
GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYVVHCQDCARKTSGNLENFVVLEQYKM
EDLMQVYDQFTLAPPLPSASS
NT seq 4206 nt   +upstreamnt  +downstreamnt
atgaaatcctgcggagtgtcgctcgctaccgccgccgctgccgccgccgctttcggtgat
gaggaaaagaaaatggcggcgggaaaagcgagcggcgagagcgaagaggcgtcccccagc
ctgacagccgaggagagggaggcgctcggcggactggacagccgcctcttcgggttcgtg
aggtttcatgaagatggcgccaggacgaaggccctactgggcaaggctgttcgctgctat
gaatctctaatcttaaaagctgaaggaaaagtggagtctgatttcttttgtcaattaggt
cacttcaacctcttattggaagattatccaaaagcattatctgcataccagaggtactac
agtttacagtctgactactggaagaatgctgcctttttatatggtcttggtttggtctac
ttccattataatgcatttcagtgggcaattaaagcatttcaggaggtgctttatgttgat
cccagcttttgtcgagccaaggaaattcatttacgacttgggcttatgttcaaagtgaac
acagactatgagtctagtttaaagcattttcagttagctttggttgactgtaatccctgc
actttgtccaatgctgaaattcaatttcacattgcccacttatatgaaacccagaggaaa
tatcattctgcaaaagaagcttatgaacaacttttgcagacagagaatctttctgcacaa
gtaaaagcaactgtcttacaacagttaggttggatgcatcacactgtagatctcctggga
gataaagctaccaaggaaagctatgctattcagtatctccaaaagtccttggaagcagat
cctaattctggccagtcctggtatttcctcggaaggtgctattcaagtattgggaaagtt
caggatgcctttatatcttacaggcagtctattgataaatcagaagcaagtgcagataca
tggtgttcaataggtgtgctatatcagcagcaaaatcagcccatggacgctttacaggcc
tatatttgtgctgtacaattggaccatggccatgctgcagcctggatggacctaggcact
ctctatgaatcctgcaaccagcctcaggatgccattaaatgctacttaaatgcaactaga
agcaaaagttgtagtaatacctctgcacttgcagcacgaattaagtatttacaggctcag
ttgtgtaaccttccacaaggtagtctacagaataaaactaaattacttcctagtattgag
gaggcgtggagcctaccaattcccgcagagcttacctccaggcagggtgccatgaacaca
gcacagcagaatacttctgacaattggagtggtggacatgctgtgtcacatcctccagta
cagcaacaagctcattcatggtgtttgacaccacagaaattacagcatttggaacagctc
cgcgcaaatagaaataatttaaatccagcacagaaactgatgctggaacagctggaaagt
cagtttgtcttaatgcaacaacaccaaatgagaccaacaggagttgcacaggtacgatct
actggaattcctaatgggccaacagctgactcatcactgcctacaaactcagtctctggc
cagcagccacagcttgctctgaccagagtgcctagcgtctctcagcctggagtccgtcct
gcctgccctgggcagcctttggccaatggacccttttctgcaggccatgttccctgtagc
acatcaagaacgctgggaagtacagacactattttgataggcaataatcatataacagga
agtggaagtaatggaaacgtgccttacctgcagcgaaacgcactcactctacctcataac
cgcacaaacctgaccagcagcgcagaggagccgtggaaaaaccaactatctaactccact
caggggcttcacaaaggtcagagttcacattcggcaggtcctaatggtgaacgacctatc
tcttccactgggccttcccagcatctccaggcagctggctctggtattcagaatcagaat
ggacatcccaccctgcctagcaattcagtaacacagggggctgctctcaatcacctctcc
tctcacactgctacctcaggtggacaacaaggcattaccttaaccaaagagagcaagcct
tcaggaaacatattgacggtgcctgaaacaagcaggcacactggagagacacctaacagc
actgccagtgtcgagggacttcctaatcatgtccatcagatgacggcagatgctgtttgc
agtcctagccatggagattctaagtcaccaggtttactaagttcagacaatcctcagctc
tctgccttgttgatgggaaaagccaataacaatgtgggtactggaacctgtgacaaagtc
aataacatccacccagctgttcatacaaagactgataactctgttgcctcttcaccatct
tcagccatttccacagcaacaccttctccaaaatccactgagcagacaaccacaaacagt
gttaccagccttaacagccctcacagtgggctacacacaattaatggagaagggatggaa
gaatctcagagccccatgaaaacagatctgcttctggttaaccacaaacctagtccacag
atcataccatcaatgtctgtgtccatataccccagctcagcagaagttctgaaggcatgc
aggaatctaggtaaaaatggcttatctaacagtagcattttgttggataaatgtccacct
ccaagaccaccatcttcaccataccctcccttgccaaaggacaagttgaatccacctaca
cctagtatttacttggaaaataaacgtgatgctttctttcctccattacatcaattttgt
acaaatccgaacaaccctgttacagtaatacgtggccttgctggagctcttaagttagac
ctgggacttttctctactaaaactttggtggaagctaacaatgaacatatggtagaagtg
aggacacagttgcagcagccagcagatgaaaactgggatcccactggaacaaagaaaatc
tggcattgtgaaagtaatagatctcatactacaattgctaaatatgcacagtaccaggcc
tcctcattccaggaatcattgagagaagaaaatgaaaaaagaagtcatcataaagaccac
tcagatagtgaatctacatcatcagataattctgggaggaggagaaaaggaccctttaaa
accataaagtttgggaccaatattgacctatctgatgacaaaaagtggaagttgcagcta
catgagctgactaaacttcctgcttttgtgcgtgtcgtatcagcaggaaatcttctaagc
catgttggtcataccatattgggcatgaacacagttcaactatacatgaaagttccaggg
agcagaacaccaggtcatcaggaaaataacaacttctgttcagttaacataaatattggc
ccaggtgactgtgaatggtttgttgttcctgaaggttactggggtgttctgaatgacttc
tgtgaaaaaaataatttgaatttcctaatgggttcttggtggcccaaccttgaagatctt
tatgaagcaaatgttccagtgtataggtttattcagcgacctggagatttggtctggata
aatgcaggcactgttcattgggttcaggctattggctggtgcaacaacattgcttggaat
gttggtccacttacagcctgccagtataaattggcagtggaacggtacgaatggaacaaa
ttgcaaagtgtgaagtcaatagtacccatggttcatctttcctggaatatggcacgaaat
atcaaggtctcagatccaaagctttttgaaatgattaagtattgtcttctaagaactctg
aagcaatgtcagacattgagggaagctctcattgctgcaggaaaagagattatatggcat
gggcggacaaaagaagaaccagctcattactgtagcatttgtgaagtggaggtttttgat
ctgctttttgtcactaatgagagtaattcacgaaagacctacgtagtacattgccaagat
tgtgcacgaaaaacaagcggaaacctggaaaactttgtggtgctagaacagtacaaaatg
gaggacctgatgcaagtctatgaccaatttacattagctcctccattaccatccgcctca
tcttga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (12)   
   UniProt (1)   
   RefSeq(pep) (11)   
DNA sequence (12)   
   RefSeq(nuc) (12)   
Protein domain (17)   
   Pfam (17)   
All databases (65)   

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