KEGG   Cutibacterium acnes SK137: HMPREF0675_3822
Entry
HMPREF0675_3822   CDS       T01215                                 
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
pak  Cutibacterium acnes SK137
Pathway
pak00300  Lysine biosynthesis
pak00550  Peptidoglycan biosynthesis
pak01100  Metabolic pathways
pak01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:pak00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    HMPREF0675_3822 (murF)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    HMPREF0675_3822 (murF)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    HMPREF0675_3822 (murF)
Enzymes [BR:pak01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     HMPREF0675_3822 (murF)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase Mur_ligase_C LpxD
Other DBs
NCBI-ProteinID: ADE00030
Position
844975..846432
AA seq 485 aa
MRVLDVATLAQWVEAAPVNDSAQVGPDVVIDTRKVTPGALFIALPGTRVDGHDFTQAAQD
TGAAAVLVTRRTDAQLPHLVVDDGQAGLSRLARHVVATERERGMRTIALTGSSGKTSTKD
MLAQILETFGPTVAPVGSFNNEIGVPLTACRSNENTSFLVSEMGTRGLGHISWLTSIVTP
DVAMVLNVGNAHLGEFGSREVIAQAKGEIVEALSVDGWAVLNAADTLVAGMAPRTRGHIA
WFSPDADHRRPDADIEVWAESTHADDLDRHSFTLAARRGESTWRSPVRLMTMGAHQVANA
VAATAAALAALAMNDDIDDQTVTRIAEALSNAVSRSAMRMQLRERADGLVLVEDCYNANP
DSMAASLTSMGHVLATRRVRDPQTRGVAVLGDMLELGQDSARLNAESGRLAAHAGFDVII
AVGDEAENIAEGARAEGARVIVSTVEGASGSLGWTSHDVVLLKASRGLALERVGREVFEE
REAQA
NT seq 1458 nt   +upstreamnt  +downstreamnt
atgagagttctcgacgttgccaccctcgcgcagtgggtcgaagcagcaccggtaaatgat
tctgcccaggtgggcccggacgtcgtcattgatacccggaaggtaactccgggcgctctg
tttatcgctcttcccggcacccgggtagacggtcatgacttcactcaggcggctcaggac
acgggcgctgccgctgtcctggtcactcggcgcaccgacgcacagttgccccatctcgtt
gttgacgatggtcaagccggcctatctcgactggcgcgtcatgtcgtggcgactgaacga
gaacgtggcatgcgtaccatcgctttgactggttccagcggtaagacaagcaccaaggac
atgctggcccagatccttgagacttttggcccaacggtggctccggtgggatcgttcaac
aatgaaatcggagttcctctgacggcgtgccgcagtaacgagaacacctctttcttggtg
tcggaaatggggactcgcggtctgggtcatatctcctggctcacctccatcgttactccc
gacgtagccatggtcctcaacgtcgggaatgcccacctgggcgagtttggttcgcgagag
gtcattgcccaggctaagggtgagatcgttgaggccctcagcgttgacggttgggctgtg
ctcaacgccgccgatacccttgtcgccgggatggcaccgcgcacccgtggacatattgca
tggttcagccctgatgctgaccatcgtcgcccagatgccgacatcgaggtgtgggccgaa
tcaacccatgccgacgacctggatcgtcactcctttacccttgccgcccgccggggtgag
tccacctggcgtagccctgtccggctgatgacgatgggtgctcatcaggtcgcaaatgcc
gtggctgctactgctgctgcgctggcagccttggctatgaatgacgacatcgatgaccaa
actgtcactcggatcgccgaggcgctcagcaacgccgtgtccaggtcagctatgagaatg
cagttgcgtgaacgcgccgatggcctggtgctggtcgaggactgctacaacgccaaccct
gactcgatggccgcttcgttgacatcgatggggcatgtcttggcgacgcgccgagttcgg
gaccctcagactaggggcgtcgccgtcttgggcgacatgctcgagcttggacaggactct
gctcgtctcaatgccgagtccggtcggctagcagcccacgctggattcgacgtcattatc
gctgttggcgatgaggccgagaacattgccgaaggtgcccgggccgaaggcgcacgtgtg
attgtttccaccgtggaaggtgcttctgggtcactaggttggacctcacacgatgtcgtt
ttactcaaagcttccagaggtctggccttggagcgagtaggacgcgaagtgttcgaggaa
agggaggcccaggcgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (4)   
   Pfam (4)   
All databases (25)   

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