| Entry |
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| Name |
Riboflavin metabolism |
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| Class |
Metabolism; Metabolism of cofactors and vitamins
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| Pathway map |
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| Module |
| M00125 | Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:rn00740] |
| M00911 | Riboflavin biosynthesis, fungi, GTP => riboflavin/FMN/FAD [PATH:rn00740] |
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| Other DBs |
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| Reaction |
| R00066 | 6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase |
| R00160 | FAD nucleotidohydrolase |
| R00161 | ATP:FMN adenylyltransferase |
| R00425 | GTP 7,8-8,9-dihydrolase (diphosphate-forming) |
| R00548 | riboflavin-5-phosphate phosphohydrolase |
| R00549 | ATP:riboflavin 5'-phosphotransferase |
| R00550 | D-glucose-1-phosphate:riboflavin 5'-phosphotransferase |
| R03458 | 5-amino-6-(5-phosphoribitylamino)uracil:NADP+ 1'-oxidoreductase |
| R03459 | 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine 2-aminohydrolase |
| R04457 | 5-amino-6-(D-ribitylamino)uracil butanedionetransferase |
| R05705 | FMNH2:NAD+ oxidoreductase |
| R05706 | FMNH2:NADP+ oxidoreductase |
| R05707 | reduced-riboflavin:NADP+ oxidoreductase |
| R07280 | 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphohydrolase |
| R07281 | D-ribulose 5-phosphate formate-lyase (L-3,4-dihydroxybutan-2-one 4-phosphate-forming) |
| R07306 | GTP 8,9-hydrolase (phosphate-forming) |
| R08574 | CTP:riboflavin 5'-phosphotransferase |
| R09374 | 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one amidohydrolase |
| R09375 | 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one:NAD+ 1'-oxidoreductase |
| R09376 | 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one:NADP+ 1'-oxidoreductase |
| R09377 | 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one 2-aminohydrolase |
| R09520 | FADH2:NADP+ oxidoreductase |
| R09748 | FADH2:NAD+ oxidoreductase |
| R09750 | reduced-riboflavin:NAD+ oxidoreductase |
| R11225 | dimethylallyl-phosphate:FMNH2 prenyltransferase |
| R12896 | prenyl diphosphate diphosphate phosphohydrolase |
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| Compound |
| C00235 | Dimethylallyl diphosphate |
| C01268 | 5-Amino-6-(5'-phosphoribosylamino)uracil |
| C01304 | 2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one |
| C04332 | 6,7-Dimethyl-8-(D-ribityl)lumazine |
| C04454 | 5-Amino-6-(5'-phospho-D-ribitylamino)uracil |
| C04732 | 5-Amino-6-(1-D-ribitylamino)uracil |
| C05995 | 7-Hydroxy-6-methyl-8-ribityllumazine |
| C15556 | L-3,4-Dihydroxybutan-2-one 4-phosphate |
| C15563 | 2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one |
| C18910 | 2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one |
| C21214 | Dimethylallyl phosphate |
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| Reference |
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| Authors |
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS. |
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| Title |
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation. |
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| Journal |
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| Reference |
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| Authors |
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A. |
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| Title |
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe. |
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| Journal |
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| Reference |
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| Authors |
Haase I, Fischer M, Bacher A, Schramek N. |
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| Title |
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus. |
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| Journal |
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| Reference |
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| Authors |
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A. |
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| Title |
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin. |
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| Journal |
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Related
pathway |
| rn00040 | Pentose and glucuronate interconversions |
| rn00900 | Terpenoid backbone biosynthesis |
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| KO pathway |
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