KEGG   PATHWAY: sty00740
Entry
sty00740                    Pathway                                
Name
Riboflavin metabolism - Salmonella enterica subsp. enterica serovar Typhi CT18
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
sty00740  Riboflavin metabolism
sty00740

Module
sty_M00125  Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:sty00740]
Other DBs
GO: 0006771
Organism
Salmonella enterica subsp. enterica serovar Typhi CT18 [GN:sty]
Gene
STY1340  ribA; GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
STY0455  ribD; riboflavin biosynthesis protein RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
STY0900  HAD superfamily hydrolase [KO:K20861] [EC:3.1.3.102 3.1.3.104]
STY3609  yigB; FMN phosphatase [KO:K20862] [EC:3.1.3.102 3.1.3.104]
STY3373  ribB; 3,4-dihydroxy-2-butanone-4-phosphate synthase [KO:K02858] [EC:4.1.99.12]
STY0456  ribH; 6,7-dimethyl-8-ribityllumazine synthase [KO:K00794] [EC:2.5.1.78]
STY1696  ribE; riboflavin synthase subunit alpha [KO:K00793] [EC:2.5.1.9]
STY0054  ribF; riboflavin biosynthesis protein RibF [KO:K11753] [EC:2.7.1.26 2.7.7.2]
STY4445  aphA; acid phosphatase AphA [KO:K03788] [EC:3.1.3.2]
STY4519  phoN; nonspecific acid phosphatase [KO:K09474] [EC:3.1.3.2]
STY1130  hpaC; 4-hydroxyphenylacetate 3-monooxygenase coupling protein [KO:K00484] [EC:1.5.1.36]
STY3580  ubiB; flavin reductase [KO:K05368] [EC:1.5.1.41]
STY2376  hydroxyethylthiazole kinase [KO:K00878] [EC:2.7.1.50]
STY3363  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
STY1275  mutT family protein [KO:K12152] [EC:3.6.1.-]
STY2586  ubiX; decarboxylase [KO:K03186] [EC:2.5.1.129]
STY3046  decarboxylase [KO:K03186] [EC:2.5.1.129]
Compound
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Reference
PMID:12136096
  Authors
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
  Title
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
  Journal
Nucleic Acids Res 30:3141-51 (2002)
DOI:10.1093/nar/30.14.3141
Reference
PMID:11856310
  Authors
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
  Title
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
  Journal
Eur J Biochem 269:519-26 (2002)
DOI:10.1046/j.0014-2956.2001.02674.x
Reference
PMID:12867427
  Authors
Haase I, Fischer M, Bacher A, Schramek N.
  Title
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
  Journal
J Biol Chem 278:37909-15 (2003)
DOI:10.1074/jbc.M303090200
Reference
PMID:16042598
  Authors
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
  Title
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
  Journal
Biochem Soc Trans 33:780-4 (2005)
DOI:10.1042/BST0330780
Related
pathway
sty00030  Pentose phosphate pathway
sty00040  Pentose and glucuronate interconversions
sty00230  Purine metabolism
sty00860  Porphyrin metabolism
sty00900  Terpenoid backbone biosynthesis
KO pathway
ko00740   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG GENES (17)   
All databases (18)   

Download RDF
DBGET integrated database retrieval system