KEGG   PATHWAY: egr00061
Entry
egr00061                    Pathway                                
Name
Fatty acid biosynthesis - Eucalyptus grandis (rose gum)
Class
Metabolism; Lipid metabolism
Pathway map
egr00061  Fatty acid biosynthesis
egr00061

Module
egr_M00082  Fatty acid biosynthesis, initiation [PATH:egr00061]
egr_M00083  Fatty acid biosynthesis, elongation [PATH:egr00061]
egr_M00086  beta-Oxidation, acyl-CoA synthesis [PATH:egr00061]
Other DBs
GO: 0006633
Organism
Eucalyptus grandis (rose gum) [GN:egr]
Gene
104448070  acetyl-CoA carboxylase 1 [KO:K11262] [EC:6.4.1.2 6.3.4.14 2.1.3.15]
104433113  acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, chloroplastic [KO:K01962] [EC:6.4.1.2 2.1.3.15]
104433112  acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, chloroplastic [KO:K01962] [EC:6.4.1.2 2.1.3.15]
104442083  LOW QUALITY PROTEIN: acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, chloroplastic [KO:K01962] [EC:6.4.1.2 2.1.3.15]
104420382  biotin carboxyl carrier protein of acetyl-CoA carboxylase, chloroplastic-like isoform X1 [KO:K02160]
104426877  biotin carboxyl carrier protein of acetyl-CoA carboxylase 1, chloroplastic [KO:K02160]
104422016  biotin carboxyl carrier protein of acetyl-CoA carboxylase 2, chloroplastic [KO:K02160]
104437302  biotin carboxylase 2, chloroplastic isoform X1 [KO:K01961] [EC:6.4.1.2 6.3.4.14]
104423091  malonate--CoA ligase isoform X1 [KO:K18660] [EC:6.2.1.76 6.2.1.-]
104422349  malonyl CoA-acyl carrier protein transacylase [KO:K00645] [EC:2.3.1.39]
104443713  3-oxoacyl-[acyl-carrier-protein] synthase 3 A, chloroplastic [KO:K00648] [EC:2.3.1.180]
104436391  3-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic [KO:K09458] [EC:2.3.1.179]
104438006  3-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic [KO:K09458] [EC:2.3.1.179]
104441672  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic [KO:K09458] [EC:2.3.1.179]
104440798  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic [KO:K09458] [EC:2.3.1.179]
104424701  3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial [KO:K09458] [EC:2.3.1.179]
104442820  NADPH-dependent aldehyde reductase-like protein, chloroplastic [KO:K00059] [EC:1.1.1.100]
104433644  3-oxoacyl-[acyl-carrier-protein] reductase 4 isoform X1 [KO:K00059] [EC:1.1.1.100]
104415707  3-oxoacyl-[acyl-carrier-protein] reductase 4 [KO:K00059] [EC:1.1.1.100]
104425260  NADPH-dependent aldehyde reductase-like protein, chloroplastic [KO:K00059] [EC:1.1.1.100]
104425256  NADPH-dependent aldehyde reductase-like protein, chloroplastic isoform X1 [KO:K00059] [EC:1.1.1.100]
104425255  NADPH-dependent aldehyde reductase-like protein, chloroplastic [KO:K00059] [EC:1.1.1.100]
104425253  LOW QUALITY PROTEIN: NADPH-dependent aldehyde reductase-like protein, chloroplastic [KO:K00059] [EC:1.1.1.100]
104425252  NADPH-dependent aldehyde reductase-like protein, chloroplastic [KO:K00059] [EC:1.1.1.100]
104419917  3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [KO:K02372] [EC:4.2.1.59]
104445826  enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic [KO:K00208] [EC:1.3.1.9 1.3.1.10]
104432956  enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic isoform X1 [KO:K00208] [EC:1.3.1.9 1.3.1.10]
104432824  enoyl-[acyl-carrier-protein] reductase, mitochondrial [KO:K07512] [EC:1.3.1.- 1.3.1.38]
104445446  enoyl-[acyl-carrier-protein] reductase, mitochondrial-like [KO:K07512] [EC:1.3.1.- 1.3.1.38]
120286245  enoyl-[acyl-carrier-protein] reductase, mitochondrial-like [KO:K07512] [EC:1.3.1.- 1.3.1.38]
104416677  LOW QUALITY PROTEIN: palmitoyl-acyl carrier protein thioesterase, chloroplastic [KO:K10781] [EC:3.1.2.14 3.1.2.21]
104438474  palmitoyl-acyl carrier protein thioesterase, chloroplastic [KO:K10781] [EC:3.1.2.14 3.1.2.21]
104436629  LOW QUALITY PROTEIN: palmitoyl-acyl carrier protein thioesterase, chloroplastic [KO:K10781] [EC:3.1.2.14 3.1.2.21]
104456526  oleoyl-acyl carrier protein thioesterase 1, chloroplastic [KO:K10782] [EC:3.1.2.14]
104456525  oleoyl-acyl carrier protein thioesterase 1, chloroplastic [KO:K10782] [EC:3.1.2.14]
104456524  oleoyl-acyl carrier protein thioesterase 1, chloroplastic [KO:K10782] [EC:3.1.2.14]
104416312  oleoyl-acyl carrier protein thioesterase, chloroplastic-like [KO:K10782] [EC:3.1.2.14]
104456523  oleoyl-acyl carrier protein thioesterase 1, chloroplastic [KO:K10782] [EC:3.1.2.14]
120287775  oleoyl-acyl carrier protein thioesterase 2, chloroplastic-like [KO:K10782] [EC:3.1.2.14]
104456206  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
104456203  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
104449632  stearoyl-[acyl-carrier-protein] 9-desaturase 6, chloroplastic [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
104456200  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
104456201  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
104456202  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
104416145  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic isoform X1 [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
104456197  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
104428010  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
104427748  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
104456204  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
104450940  long chain acyl-CoA synthetase 9, chloroplastic [KO:K01897] [EC:6.2.1.3]
104451635  long chain acyl-CoA synthetase 6, peroxisomal [KO:K01897] [EC:6.2.1.3]
104441657  long chain acyl-CoA synthetase 4 [KO:K01897] [EC:6.2.1.3]
104415559  long chain acyl-CoA synthetase 7, peroxisomal isoform X1 [KO:K01897] [EC:6.2.1.3]
104452660  long chain acyl-CoA synthetase 2 [KO:K01897] [EC:6.2.1.3]
104456627  LOW QUALITY PROTEIN: long chain acyl-CoA synthetase 1 [KO:K01897] [EC:6.2.1.3]
104456625  long chain acyl-CoA synthetase 1 isoform X1 [KO:K01897] [EC:6.2.1.3]
104414262  LOW QUALITY PROTEIN: probable acyl-activating enzyme 16, chloroplastic [KO:K01897] [EC:6.2.1.3]
104425207  long chain acyl-CoA synthetase 8 [KO:K01897] [EC:6.2.1.3]
104417699  long chain acyl-CoA synthetase 7, peroxisomal-like [KO:K01897] [EC:6.2.1.3]
Compound
C00024  Acetyl-CoA
C00083  Malonyl-CoA
C00154  Palmitoyl-CoA
C00173  Acyl-[acyl-carrier protein]
C00229  Acyl-carrier protein
C00249  Hexadecanoic acid
C00383  Malonate
C00638  Long-chain fatty acid
C00685  3-Oxoacyl-[acyl-carrier protein]
C00693  trans-2,3-Dehydroacyl-[acyl-carrier protein]
C00712  (9Z)-Octadecenoic acid
C01203  Oleoyl-[acyl-carrier protein]
C01209  Malonyl-[acyl-carrier protein]
C01271  (3R)-3-Hydroxyacyl-[acyl-carrier protein]
C01530  Octadecanoic acid
C01571  Decanoic acid
C02679  Dodecanoic acid
C02843  Long-chain acyl-CoA
C03939  Acetyl-[acyl-carrier protein]
C04088  Octadecanoyl-[acyl-carrier protein]
C04180  cis-Dec-3-enoyl-[acp]
C04246  But-2-enoyl-[acyl-carrier protein]
C04618  (3R)-3-Hydroxybutanoyl-[acyl-carrier protein]
C04619  (3R)-3-Hydroxydecanoyl-[acyl-carrier protein]
C04620  (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein]
C04633  (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
C04688  (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
C05223  Dodecanoyl-[acyl-carrier protein]
C05744  Acetoacetyl-[acp]
C05745  Butyryl-[acp]
C05746  3-Oxohexanoyl-[acp]
C05747  (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein]
C05748  trans-Hex-2-enoyl-[acp]
C05749  Hexanoyl-[acp]
C05750  3-Oxooctanoyl-[acp]
C05751  trans-Oct-2-enoyl-[acp]
C05752  Octanoyl-[acp]
C05753  3-Oxodecanoyl-[acp]
C05754  trans-Dec-2-enoyl-[acp]
C05755  Decanoyl-[acp]
C05756  3-Oxododecanoyl-[acp]
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05758  trans-Dodec-2-enoyl-[acp]
C05759  3-Oxotetradecanoyl-[acp]
C05760  trans-Tetradec-2-enoyl-[acp]
C05761  Tetradecanoyl-[acp]
C05762  3-Oxohexadecanoyl-[acp]
C05763  trans-Hexadec-2-enoyl-[acp]
C05764  Hexadecanoyl-[acp]
C06423  Octanoic acid
C06424  Tetradecanoic acid
C08362  (9Z)-Hexadecenoic acid
C16219  3-Oxostearoyl-[acp]
C16220  (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein]
C16221  (2E)-Octadecenoyl-[acp]
C16520  Hexadecenoyl-[acyl-carrier protein]
C20683  Long-chain acyl-[acyl-carrier protein]
C20794  n-7 Unsaturated acyl-[acyl-carrier protein]
Reference
  Authors
Salas JJ, Ohlrogge JB.
  Title
Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases.
  Journal
Arch Biochem Biophys 403:25-34 (2002)
DOI:10.1016/S0003-9861(02)00017-6
Reference
  Authors
Zhang YM, Marrakchi H, White SW, Rock CO.
  Title
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.
  Journal
J Lipid Res 44:1-10 (2003)
DOI:10.1194/jlr.R200016-JLR200
Reference
  Authors
Voelker T, Kinney AJ.
  Title
VARIATIONS IN THE BIOSYNTHESIS OF SEED-STORAGE LIPIDS.
  Journal
Annu Rev Plant Physiol Plant Mol Biol 52:335-361 (2001)
DOI:10.1146/annurev.arplant.52.1.335
Reference
  Authors
Barker GC, Larson TR, Graham IA, Lynn JR, King GJ.
  Title
Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait Loci analysis of the Brassica C genome.
  Journal
Plant Physiol 144:1827-42 (2007)
DOI:10.1104/pp.107.096172
Reference
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
  Authors
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z
  Title
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
  Journal
Nat Commun 5:4805 (2014)
DOI:10.1038/ncomms5805
Reference
  Authors
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ
  Title
Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.
  Journal
Prog Lipid Res 49:27-45 (2010)
DOI:10.1016/j.plipres.2009.08.001
Reference
  Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
  Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
  Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:10.1016/j.bbalip.2016.08.011
Related
pathway
egr00020  Citrate cycle (TCA cycle)
egr00062  Fatty acid elongation
egr00071  Fatty acid degradation
egr00410  beta-Alanine metabolism
egr00561  Glycerolipid metabolism
egr00564  Glycerophospholipid metabolism
egr00620  Pyruvate metabolism
egr00785  Lipoic acid metabolism
KO pathway
ko00061   

DBGET integrated database retrieval system