KEGG   PATHWAY: ldo00330
Entry
ldo00330                    Pathway                                
Name
Arginine and proline metabolism - Leishmania donovani
Class
Metabolism; Amino acid metabolism
Pathway map
ldo00330  Arginine and proline metabolism
ldo00330

Module
ldo_M00015  Proline biosynthesis, glutamate => proline [PATH:ldo00330]
ldo_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:ldo00330]
ldo_M00970  Proline degradation, proline => glutamate [PATH:ldo00330]
Other DBs
GO: 0006525 0006560
Organism
Leishmania donovani [GN:ldo]
Gene
LDBPK_230080  agmatinase-like protein [KO:K01480] [EC:3.5.3.11]
LDBPK_120105  hypothetical protein [KO:K01581] [EC:4.1.1.17]
LDBPK_040570  spermidine synthase, putative [KO:K00797] [EC:2.5.1.16]
LDBPK_303150  S-adenosylmethionine decarboxylase [KO:K01611] [EC:4.1.1.50]
LDBPK_251160  aldehyde dehydrogenase, mitochondrial precursor [KO:K00128] [EC:1.2.1.3]
LDBPK_351490  arginase [KO:K01476] [EC:3.5.3.1]
LDBPK_131420  pyrroline-5-carboxylate reductase [KO:K00286] [EC:1.5.1.2]
LDBPK_261590  proline oxidase, mitochondrial precursor-like protein [KO:K00318] [EC:1.5.5.2]
LDBPK_030190  delta-1-pyrroline-5-carboxylate dehydrogenase, putative [KO:K00294] [EC:1.2.1.88]
LDBPK_262740  glutamate 5-kinase, putative [KO:K00931] [EC:2.7.2.11]
LDBPK_323340  pyrroline-5-carboxylate synthetase-like protein [KO:K00147] [EC:1.2.1.41]
LDBPK_350840  aspartate aminotransferase, putative [KO:K14454] [EC:2.6.1.1]
LDBPK_240370  aspartate aminotransferase, putative [KO:K14455] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
ldo00020  Citrate cycle (TCA cycle)
ldo00220  Arginine biosynthesis
ldo00250  Alanine, aspartate and glutamate metabolism
ldo00260  Glycine, serine and threonine metabolism
ldo00270  Cysteine and methionine metabolism
ldo00310  Lysine degradation
ldo00410  beta-Alanine metabolism
ldo00480  Glutathione metabolism
ldo00630  Glyoxylate and dicarboxylate metabolism
ldo00650  Butanoate metabolism
ldo00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG GENES (13)   
All databases (14)   

Download RDF
DBGET integrated database retrieval system