KEGG   PATHWAY: mul00230
Entry
mul00230                    Pathway                                
Name
Purine metabolism - Mycobacterium ulcerans
Class
Metabolism; Nucleotide metabolism
Pathway map
mul00230  Purine metabolism
mul00230

Module
mul_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mul00230]
mul_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mul00230]
mul_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mul00230]
mul_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mul00230]
mul_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mul00230]
mul_M00546  Purine degradation, xanthine => urea [PATH:mul00230]
Other DBs
GO: 0006163 0042278
Organism
Mycobacterium ulcerans [GN:mul]
Gene
MUL_3442  pgmA; phosphoglucomutase PgmA [KO:K01835] [EC:5.4.2.2]
MUL_4638  prsA; ribose-phosphate pyrophosphokinase PrsA [KO:K00948] [EC:2.7.6.1]
MUL_0417  purF; amidophosphoribosyltransferase, PurF [KO:K00764] [EC:2.4.2.14]
MUL_0481  purD; phosphoribosylamine-glycine ligase, PurD [KO:K01945] [EC:6.3.4.13]
MUL_4713  purN; 5'-phosphoribosylglycinamide formyltransferase PurN [KO:K11175] [EC:2.1.2.2]
MUL_0410  purL; phosphoribosylformylglycinamidine synthase II, PurL [KO:K23269] [EC:6.3.5.3]
MUL_0400  conserved protein [KO:K23264] [EC:6.3.5.3]
MUL_0401  purQ; phosphoribosylformylglycinamidine synthase I, PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
MUL_0418  purM; 5'-phosphoribosyl-5-aminoimidazole synthetase, PurM [KO:K01933] [EC:6.3.3.1]
MUL_2628  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit PurK (air carboxylase) (AirC) [KO:K01589] [EC:6.3.4.18]
MUL_2627  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit PurE (air carboxylase) (AirC) [KO:K01588] [EC:5.4.99.18]
MUL_0497  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase, PurC [KO:K01923] [EC:6.3.2.6]
MUL_0490  purB; adenylosuccinate lyase, PurB [KO:K01756] [EC:4.3.2.2]
MUL_4712  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
MUL_1728  apt; adenine phosphoribosyltransferase, Apt [KO:K00759] [EC:2.4.2.7]
MUL_2673  deoD; purine nucleoside phosphorylase DeoD [KO:K03783] [EC:2.4.2.1]
MUL_3497  yfiH; conserved membrane protein YfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
MUL_4200  hpt; hypoxanthine-guanine phosphoribosyltransferase Hpt [KO:K00760] [EC:2.4.2.8]
MUL_0900  guaB2; inosine-5'-monophosphate (imp) dehydrogenase, GuaB2 [KO:K00088] [EC:1.1.1.205]
MUL_0901  guaB3; inosine-5'-monophosphate (imp) dehydrogenase, GuaB3 [KO:K00088] [EC:1.1.1.205]
MUL_3716  ndkA; nucleoside diphosphate kinase NdkA [KO:K00940] [EC:2.7.4.6]
MUL_3906  Ham1-related NTPase [KO:K01519] [EC:3.6.1.66]
MUL_4580  coxL_1; carbon monoxyde dehydrogenase (large chain), CoxL_1 [KO:K11177] [EC:1.17.1.4]
MUL_4579  coxM_1; carbon monoxyde dehydrogenase (medium chain), CoxM_1 [KO:K11178] [EC:1.17.1.4]
MUL_4578  coxS_1; carbon monoxyde dehydrogenase (small chain), CoxS_1 [KO:K13483]
MUL_0913  guaA; GMP synthase, GuaA [KO:K01951] [EC:6.3.5.2]
MUL_3036  guaB1; inosine-5'-monophosphate dehydrogenase GuaB1 [KO:K26110] [EC:1.7.1.7]
MUL_1788  gmk; guanylate kinase Gmk [KO:K00942] [EC:2.7.4.8]
MUL_1878  nrdE; ribonucleoside-diphosphate reductase (alpha chain) NrdE [KO:K00525] [EC:1.17.4.1]
MUL_1883  nrdF2; ribonucleoside-diphosphate reductase (beta chain) NrdF2 [KO:K00526] [EC:1.17.4.1]
MUL_1458  dgt; deoxyguanosine triphosphate triphosphohydrolase Dgt [KO:K01129] [EC:3.1.5.1]
MUL_1729  relA; GTP pyrophosphokinase RelA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
MUL_4628  conserved hypothetical protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MUL_4566  conserved protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MUL_1472  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
MUL_4470  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
MUL_0687  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
MUL_3944  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
MUL_0150  conserved hypothetical protein [KO:K01768] [EC:4.6.1.1]
MUL_4221  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
MUL_2284  conserved hypothetical protein [KO:K01768] [EC:4.6.1.1]
MUL_3594  adenylylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
MUL_3986  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
MUL_4617  conserved hypothetical transmembrane protein [KO:K01768] [EC:4.6.1.1]
MUL_4940  cyaA; adenylate cyclase, CyaA [KO:K01768] [EC:4.6.1.1]
MUL_2834  purA; adenylosuccinate synthetase PurA [KO:K01939] [EC:6.3.4.4]
MUL_3559  cbhK; carbohydrate kinase CbhK [KO:K00856] [EC:2.7.1.20]
MUL_1364  add; adenosine deaminase Add [KO:K01488] [EC:3.5.4.4]
MUL_0829  adk; adenylate kinase (ATP-AMP transphosphorylase), Adk [KO:K00939] [EC:2.7.4.3]
MUL_3470  conserved hypothetical protein [KO:K04765] [EC:3.6.1.9]
MUL_4633  conserved hypothetical protein [KO:K04765] [EC:3.6.1.9]
MUL_0412  conserved hypothetical protein [KO:K03651] [EC:3.1.4.53]
MUL_3255  conserved protein [KO:K19710] [EC:2.7.7.53]
MUL_3995  cysN; bifunctional enzyme CysN/CysC: sulfate adenyltransferase (subunit 1) + adenylylsulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
MUL_3996  cysD; sulfate adenylyltransferase subunit 2 CysD [KO:K00957] [EC:2.7.7.4]
MUL_0460  conserved hypothetical protein [KO:K16839] [EC:1.14.13.113]
MUL_0457  conserved hypothetical protein [KO:K07127] [EC:3.5.2.17]
MUL_0456  conserved protein [KO:K16840] [EC:4.1.1.97]
MUL_4626  hydantoin racemase [KO:K16841] [EC:5.1.99.3]
MUL_2681  chitinase [KO:K16842] [EC:3.5.2.5]
MUL_2682  alc; allantoicase Alc [KO:K01477] [EC:3.5.3.4]
MUL_3029  ureC; urease alpha subunit UreC [KO:K01428] [EC:3.5.1.5]
MUL_3030  ureB; urease beta subunit UreB [KO:K01429] [EC:3.5.1.5]
MUL_3031  ureA; urease gamma subunit UreA [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mul00030  Pentose phosphate pathway
mul00220  Arginine biosynthesis
mul00250  Alanine, aspartate and glutamate metabolism
mul00260  Glycine, serine and threonine metabolism
mul00340  Histidine metabolism
mul00630  Glyoxylate and dicarboxylate metabolism
mul00730  Thiamine metabolism
mul00740  Riboflavin metabolism
mul00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (64)   
   KEGG GENES (64)   
All databases (65)   

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