GenomeNet

Database: Pfam
Entry: ApoC-I
LinkDB: ApoC-I
Original site: ApoC-I 
#=GF ID   ApoC-I
#=GF AC   PF04691.14
#=GF DE   Apolipoprotein C-I (ApoC-1)
#=GF AU   Kerrison ND;0000-0002-1471-953X
#=GF SE   DOMO:DM04729;
#=GF GA   28.30 28.30;
#=GF TC   28.60 29.50;
#=GF NC   28.00 27.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Apolipoprotein_C1
#=GF RN   [1]
#=GF RM   11580293
#=GF RT   Solution conformation of human apolipoprotein C-1 inferred from
#=GF RT   proline mutagenesis: far- and near-UV CD study. 
#=GF RA   Gursky O; 
#=GF RL   Biochemistry 2001;40:12178-12185.
#=GF RN   [2]
#=GF RM   11353333
#=GF RT   Apolipoproteins C-I and C-III as important modulators of
#=GF RT   lipoprotein metabolism. 
#=GF RA   Shachter NS; 
#=GF RL   Curr Opin Lipidol 2001;12:297-304.
#=GF RN   [3]
#=GF RM   11741391
#=GF RT   Apolipoprotein C-I expression in the brain in Alzheimer's
#=GF RT   disease. 
#=GF RA   Petit-Turcotte C, Stohl SM, Beffert U, Cohn JS, Aumont N,
#=GF RA   Tremblay M, Dea D, Yang L, Poirier J, Shachter NS; 
#=GF RL   Neurobiol Dis 2001;8:953-963.
#=GF DR   INTERPRO; IPR006781;
#=GF DR   SCOP; 1ale; fa;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Apolipoprotein C-I (ApoC-1) is a water-soluble protein component
#=GF CC   of plasma lipoprotein.  It solubalises lipids and regulates
#=GF CC   lipid metabolism.  ApoC-1 transfers among HDL (high density
#=GF CC   lipoprotein), VLDL (very low-density lipoprotein) and
#=GF CC   chylomicrons.  ApoC-1 activates lecithin:choline
#=GF CC   acetyltransferase (LCAT), inhibits cholesteryl ester transfer
#=GF CC   protein, can inhibit hepatic lipase and phospholipase 2 and can
#=GF CC   stimulate cell growth. ApoC-1 delays the clearance of beta-VLDL
#=GF CC   by inhibiting its uptake via the LDL receptor-related pathway
#=GF CC   [1]. ApoC-1 has been implicated in hypertriglyceridemia [2], and
#=GF CC   Alzheimer's disease [3].
#=GF SQ   154
#=GS APOC1_AOTNA/30-86         AC P0DKV2.1
#=GS A0A556TZ45_BAGYA/23-71    AC A0A556TZ45.1
#=GS Q4QY83_SPAAU/22-82        AC Q4QY83.1
#=GS A0A4Z2JIX3_9TELE/24-83    AC A0A4Z2JIX3.1
#=GS A0A2K6KMR3_RHIBE/7-46     AC A0A2K6KMR3.1
#=GS L9L7Z9_TUPCH/27-77        AC L9L7Z9.1
#=GS A0A0D9S1R2_CHLSB/27-65    AC A0A0D9S1R2.1
#=GS A0A3S2M9X4_ORYJA/34-94    AC A0A3S2M9X4.1
#=GS A0A091EE09_FUKDA/27-87    AC A0A091EE09.1
#=GS A0A2K5YTZ0_MANLE/27-83    AC A0A2K5YTZ0.1
#=GS A0A060XXG0_ONCMY/14-74    AC A0A060XXG0.1
#=GS A0A2K5SID6_CEBCA/30-69    AC A0A2K5SID6.1
#=GS I6L580_PONAB/27-83        AC I6L580.1
#=GS K7EKP1_HUMAN/27-53        AC K7EKP1.8
#=GS A0A341DEC7_NEOAA/27-87    AC A0A341DEC7.1
#=GS A0A2Y9GG65_NEOSC/101-161  AC A0A2Y9GG65.1
#=GS A0A484D834_PERFV/58-117   AC A0A484D834.1
#=GS APOC1_NEOSC/27-87         AC P0DPH2.1
#=GS M7BAL9_CHEMY/27-76        AC M7BAL9.1
#=GS A0A452QM77_URSAM/28-88    AC A0A452QM77.1
#=GS A0A1U7SQ56_CARSF/27-83    AC A0A1U7SQ56.1
#=GS A0A1U7SMQ6_ALLSI/27-87    AC A0A1U7SMQ6.1
#=GS M0R547_RAT/27-87          AC M0R547.1
#=GS APOC1_URSMA/27-87         AC P0DPH6.1
#=GS K7ELM9_HUMAN/27-66        AC K7ELM9.1
#=GS A0A5E4BPC2_MARMO/53-113   AC A0A5E4BPC2.1
#=GS A0A0G2K9R5_RAT/27-69      AC A0A0G2K9R5.1
#=GS A0A6I8R0U8_XENTR/29-84    AC A0A6I8R0U8.1
#=GS A0A2I3S0Y0_PANTR/27-66    AC A0A2I3S0Y0.1
#=GS A0A3Q3LIT6_9TELE/22-82    AC A0A3Q3LIT6.1
#=GS A0A3Q2ECG4_CYPVA/22-82    AC A0A3Q2ECG4.1
#=GS A0A3Q3W075_MOLML/23-76    AC A0A3Q3W075.1
#=GS A0A2I2Y9E5_GORGO/27-66    AC A0A2I2Y9E5.1
#=GS A0A2K5UBW4_MACFA/27-66    AC A0A2K5UBW4.1
#=GS A0A2K5YU00_MANLE/27-66    AC A0A2K5YU00.1
#=GS A0A2Y9GD53_NEOSC/27-87    AC A0A2Y9GD53.1
#=GS A0A672FCP2_SALFA/22-76    AC A0A672FCP2.1
#=GS A0A4W5Q185_9TELE/47-107   AC A0A4W5Q185.1
#=GS A0A672YEM5_9TELE/22-81    AC A0A672YEM5.1
#=GS A0A2I2YNH6_GORGO/27-83    AC A0A2I2YNH6.1
#=GS A0A3P9NB05_POERE/21-81    AC A0A3P9NB05.1
#=GS A0A2K6KMS7_RHIBE/7-46     AC A0A2K6KMS7.1
#=GS APO1A_PANTR/27-83         AC P0CE37.1
#=GS APOC1_SAIBB/31-86         AC P0DKV5.1
#=GS APOC1_RABIT/1-28          AC P33047.1
#=GS A0A2K5N8J7_CERAT/27-66    AC A0A2K5N8J7.1
#=GS A0A452SDT4_URSAM/63-123   AC A0A452SDT4.1
#=GS A0A3Q7TP54_URSAR/27-87    AC A0A3Q7TP54.1
#=GS A0A498LXY1_LABRO/23-78    AC A0A498LXY1.1
#=GS A0A2U3VZJ4_ODORO/27-87    AC A0A2U3VZJ4.1
#=GS A0A2S3QKY3_9PROT/35-95    AC A0A2S3QKY3.1
#=GS A0A3B5Q6K8_XIPMA/78-138   AC A0A3B5Q6K8.1
#=GS A0A1L8FN76_XENLA/29-88    AC A0A1L8FN76.1
#=GS APO1A_GORGO/27-83         AC P0CF78.1
#=GS A0A671ED92_RHIFE/25-82    AC A0A671ED92.1
#=GS A0A5A9N2T2_9TELE/23-83    AC A0A5A9N2T2.1
#=GS APO1B_MACNE/27-83         AC P0DOA2.1
#=GS A0A2K6BA99_MACNE/27-66    AC A0A2K6BA99.1
#=GS A0A553QTW6_9TELE/103-163  AC A0A553QTW6.1
#=GS K7EPF9_HUMAN/27-66        AC K7EPF9.1
#=GS APOC1_HUMAN/27-83         AC P02654.1
#=GS APOC1_HUMAN/27-83         DR PDB; 6DZ6 A; 3-54;
#=GS APOC1_HUMAN/27-83         DR PDB; 1ALE A; 1-18;
#=GS APOC1_HUMAN/27-83         DR PDB; 6DVU B; 3-55;
#=GS APOC1_HUMAN/27-83         DR PDB; 6NF3 B; 4-54;
#=GS APOC1_HUMAN/27-83         DR PDB; 1IOJ A; 1-57;
#=GS APOC1_HUMAN/27-83         DR PDB; 1OPP A; 1-38;
#=GS APOC1_HUMAN/27-83         DR PDB; 6DXR B; 2-57;
#=GS APOC1_HUMAN/27-83         DR PDB; 6DXR A; 5-55;
#=GS APOC1_HUMAN/27-83         DR PDB; 6DVU A; 5-55;
#=GS APOC1_HUMAN/27-83         DR PDB; 6DZ6 B; 5-54;
#=GS APOC1_HUMAN/27-83         DR PDB; 6NF3 A; 8-53;
#=GS APOC1_HUMAN/27-83         DR PDB; 1ALF A; 1-19;
#=GS APO1A_PONAB/27-83         AC P0CE39.1
#=GS A0A3Q3E7A6_9LABR/23-82    AC A0A3Q3E7A6.1
#=GS A0A1S3GHG3_DIPOR/27-83    AC A0A1S3GHG3.1
#=GS APO1B_MACFA/27-83         AC P18657.2
#=GS A0A671WK28_SPAAU/22-73    AC A0A671WK28.1
#=GS APOC1_MOUSE/27-87         AC P34928.1
#=GS A0A2K6QV44_RHIRO/27-66    AC A0A2K6QV44.1
#=GS APO1B_MACMU/27-83         AC H9FNA4.1
#=GS A0A2R9BCB5_PANPA/27-67    AC A0A2R9BCB5.1
#=GS A0A2I3TRS5_PANTR/27-66    AC A0A2I3TRS5.1
#=GS A0A5J5DEI4_9PERO/22-82    AC A0A5J5DEI4.1
#=GS A0A4W6DAT6_LATCA/22-82    AC A0A4W6DAT6.1
#=GS A0A3Q7U1S2_VULVU/27-87    AC A0A3Q7U1S2.1
#=GS A0A3Q4AWR8_MOLML/23-77    AC A0A3Q4AWR8.1
#=GS F7F732_CALJA/31-69        AC F7F732.3
#=GS A0A1S3RYY8_SALSA/24-84    AC A0A1S3RYY8.1
#=GS APOC1_LEPWE/27-87         AC P0DM83.1
#=GS A0A2I3M1V7_PAPAN/27-66    AC A0A2I3M1V7.1
#=GS APOC1_RAT/27-87           AC P19939.1
#=GS A0A3Q3AYU5_KRYMA/20-79    AC A0A3Q3AYU5.1
#=GS A0A2Y9TD48_PHYMC/27-87    AC A0A2Y9TD48.1
#=GS A0A3Q2X0K0_HAPBU/23-83    AC A0A3Q2X0K0.1
#=GS A0A2Q0E1U3_CEBCA/30-86    AC A0A2Q0E1U3.1
#=GS K7EJI9_HUMAN/27-66        AC K7EJI9.1
#=GS A0A3B3IF59_ORYLA/20-80    AC A0A3B3IF59.1
#=GS A0A2Y9L3B7_ENHLU/27-87    AC A0A2Y9L3B7.1
#=GS F6R091_MONDO/26-86        AC F6R091.2
#=GS A0A5F4W3B1_CALJA/31-86    AC A0A5F4W3B1.1
#=GS A0A1S3WNK4_ERIEU/27-86    AC A0A1S3WNK4.1
#=GS A0A3P8W7U9_CYNSE/22-78    AC A0A3P8W7U9.1
#=GS B5XE16_SALSA/24-84        AC B5XE16.1
#=GS A0A674B6Z2_SALTR/24-84    AC A0A674B6Z2.1
#=GS A0A3N0YNU0_ANAGA/23-83    AC A0A3N0YNU0.1
#=GS APO1B_PANTR/27-83         AC P0CE38.1
#=GS B6S6L6_RABIT/27-86        AC B6S6L6.1
#=GS A0A485MLC3_LYNPA/27-87    AC A0A485MLC3.1
#=GS A0A4W5MAZ8_9TELE/24-84    AC A0A4W5MAZ8.1
#=GS A0A2U3VZJ8_ODORO/101-161  AC A0A2U3VZJ8.1
#=GS A0A2U3Y4E1_LEPWE/27-87    AC A0A2U3Y4E1.1
#=GS A0A4W4ELN8_ELEEL/23-72    AC A0A4W4ELN8.1
#=GS A0A2K6I494_PANTR/27-84    AC A0A2K6I494.1
#=GS A0A667YDZ3_9TELE/19-79    AC A0A667YDZ3.1
#=GS A0A6A5FEI1_PERFL/73-132   AC A0A6A5FEI1.1
#=GS APO1A_CERAT/25-81         AC P0DPG0.1
#=GS A0A402FNK0_9SAUR/82-142   AC A0A402FNK0.1
#=GS A0A3Q1I8I3_ANATE/22-77    AC A0A3Q1I8I3.1
#=GS A0A2Y9RTQ3_TRIMA/28-84    AC A0A2Y9RTQ3.1
#=GS G3TCR3_LOXAF/27-69        AC G3TCR3.1
#=GS APO1B_PONAB/27-65         AC P0CE40.1
#=GS A0A0P7YF15_SCLFO/30-85    AC A0A0P7YF15.1
#=GS A0A2I3SWP8_PANTR/27-66    AC A0A2I3SWP8.1
#=GS A0A060YLA8_ONCMY/24-84    AC A0A060YLA8.1
#=GS A0A4W4EPP7_ELEEL/23-83    AC A0A4W4EPP7.1
#=GS APO1B_CERAT/27-83         AC P0DPG1.1
#=GS A0A3B1J6A2_ASTMX/65-125   AC A0A3B1J6A2.1
#=GS A0A3P9B4G7_9CICH/23-66    AC A0A3P9B4G7.1
#=GS K7ERI9_HUMAN/27-77        AC K7ERI9.1
#=GS APOC1_CANLF/27-87         AC P56595.1
#=GS A0A1U7QUM6_MESAU/27-87    AC A0A1U7QUM6.1
#=GS A0A671WQU2_SPAAU/22-82    AC A0A671WQU2.1
#=GS A0A452SDT0_URSAM/76-136   AC A0A452SDT0.1
#=GS APOC1_ODORO/27-87         AC P0DPH4.1
#=GS A0A5E4BLF1_MARMO/53-112   AC A0A5E4BLF1.1
#=GS G5CBM5_HETGA/27-87        AC G5CBM5.1
#=GS A0A669BT51_ORENI/23-84    AC A0A669BT51.1
#=GS A0A3Q7TWR0_VULVU/27-87    AC A0A3Q7TWR0.1
#=GS G1M242_AILME/27-87        AC G1M242.1
#=GS A0A5C6ME59_9TELE/22-82    AC A0A5C6ME59.1
#=GS A0A6Q2XFS8_ESOLU/33-93    AC A0A6Q2XFS8.1
#=GS A0A087XQE1_POEFO/26-68    AC A0A087XQE1.1
#=GS APO1A_PANPA/27-83         AC P86336.2
#=GS APO1A_MACFA/25-81         AC P0DTQ3.1
#=GS H0WAV6_CAVPO/27-87        AC H0WAV6.2
#=GS APOC1_OTOGA/27-80         AC P0DMP0.1
#=GS APO1A_MACMU/25-81         AC G8F204.1
#=GS A0A2K6QV36_RHIRO/27-83    AC A0A2K6QV36.1
#=GS A0A4D9DJX7_9SAUR/41-100   AC A0A4D9DJX7.1
#=GS A0A5S6DCB0_CANLF/27-70    AC A0A5S6DCB0.1
#=GS A0A674DB74_SALTR/24-84    AC A0A674DB74.1
#=GS A0A2Y9E9C7_TRIMA/27-83    AC A0A2Y9E9C7.1
#=GS E9QFX0_DANRE/23-83        AC E9QFX0.1
#=GS A0A1A6FVC0_NEOLE/27-87    AC A0A1A6FVC0.1
#=GS A0A2K5TIZ9_GORGO/27-66    AC A0A2K5TIZ9.1
#=GS A0A3Q0FT94_ALLSI/212-272  AC A0A3Q0FT94.1
#=GS A0A5N5Q534_PANHP/77-137   AC A0A5N5Q534.1
#=GS G3NGS3_GASAC/26-86        AC G3NGS3.1
#=GS A0A2Y9NT54_DELLE/27-87    AC A0A2Y9NT54.1
#=GS APO1B_PAPAN/27-83         AC A0A096P2H7.1
#=GS E9QDI1_DANRE/24-84        AC E9QDI1.1
#=GS A0A1S3N6L4_SALSA/24-84    AC A0A1S3N6L4.1
#=GS A0A669DZ96_ORENI/23-73    AC A0A669DZ96.1
#=GS A0A315VB23_GAMAF/22-76    AC A0A315VB23.1
#=GS M3Y497_MUSPF/27-87        AC M3Y497.1
APOC1_AOTNA/30-86                    avdtssgl------------DKLKEFGTTLEDKVREFFNRVKESDIPAKTR.N...WFSETLQKVK...EKLRIE-s........
A0A556TZ45_BAGYA/23-71               .......e-PATEDHFANIYAKLGEFGADLTEKTTSALKQIEESEFATNA-.-...----------...-------kdlkakv..
Q4QY83_SPAAU/22-82                   .......e-ETMEQKFTQFGERVTQVGQDLAEKAKTAFDSIHNSEAMTKTR.D...WFAEQLEALK...AKVQE--is.......
A0A4Z2JIX3_9TELE/24-83               .......e-ETIEQRFANFGQQMAEVTKSLAEKAKTTFTDVHNSEFATESR.N...WFQKQFDTLK...EKINS--q........
A0A2K6KMR3_RHIBE/7-46                .......v-PDVSNPF----DVLEEFGKTLEDNVREVIKLITQSELPAKTR.-...----------...-------l........
L9L7Z9_TUPCH/27-77                   ........APDFSSTLEGLPDKLKEFGNTLEDKAKKAIERIKQSDLPAKTR.S...CLQ-------...-------sase.....
A0A0D9S1R2_CHLSB/27-65               ........APDVSSAL----DKLKEFGNTLEDKAWEVINRIKQSELPAKTR.-...----------...-------.........
A0A3S2M9X4_ORYJA/34-94               ......aq--EEDQTYTKIRDQLTEFGKTFAEKAKTTFDTIQTSEFAETTR.N...WFTSTFDKIK...TKFDE--mn.......
A0A091EE09_FUKDA/27-87               ........ASDFTSTLEGLPAKLKEFGSALENKARAAIEHIKQSDLPAKTR.N...LLSEAVSKIR...EKFKASF.........
A0A2K5YTZ0_MANLE/27-83               ........APDVSSAL----DKLKEFGNTLEDKAWEVINRIKQSEFPAKTW.D...WFSETFRKVK...EKLKIN-s........
A0A060XXG0_ONCMY/14-74               .......e-KTIEEHFTTFGNQMKDLSEDLTVKTKDIVEKIGDSEFITKTR.T...WFTEQFDKMK...AKIDETF.........
A0A2K5SID6_CEBCA/30-69               avdassgl------------DKLKEFGNTLENKVREFFSRIKESDIPTKTR.-...----------...-------l........
I6L580_PONAB/27-83                   ........APDVSSAL----DKLKEFGNTLEDKAREVINRIKQSELSAKTR.D...WFSETFRRVK...EKLKID-s........
K7EKP1_HUMAN/27-53                   ........TPDVSSAL----DKLKEFGNTLEDKARELI-------------.-...----------...-------s........
A0A341DEC7_NEOAA/27-87               .......g-PDINSILDYILEXVKEFGNTLEEKTWGVVDYIKQTNIPPKAW.H...WLSGIFHKIE...EGLNTTS.........
A0A2Y9GG65_NEOSC/101-161             ........APEISSTLGRIPDKLKEFGNTLEDKARAAIDSIKQSDIPAKTR.N...WFSETFNKVK...EQLKTAF.........
A0A484D834_PERFV/58-117              .......e-ETIEQKLAAFQDRLNEMGKTLAEKAKTTFEQVHTSELAVNAQ.N...WFREQYENLK...AKV----gei......
APOC1_NEOSC/27-87                    ........APEISSTLGRIPDKLKEFGNTLEDKARAAIDSIKQSDIPAKTR.N...WFSETFNKVK...EQLKTAF.........
M7BAL9_CHEMY/27-76                   ......el--TLSEKFENFQNRLQAFADSIANITKAAFQELHHSELSEKTR.-...----------...-------ctcfiwf..
A0A452QM77_URSAM/28-88               ........ASQISRTLDCIPDKLTEFGNGLEDKAQADIESIKQSDIPVKTR.N...WVLETFNKVK...EWFNTIF.........
A0A1U7SQ56_CARSF/27-83               ........APDGSSAL----DKLKDLGQTLGEKAREVIDRIKQSEISTKTR.N...WFSETLQKVK...EKLKID-s........
A0A1U7SMQ6_ALLSI/27-87               ........EPTLMQKLEQFKENVKDFADTIGEKTKAALQELRDSEFSTKTR.N...WFSEHFKKVK...EKLKDTF.........
M0R547_RAT/27-87                     ........APDLSGTLESIPDKLKEFGNTLEDKARAAIEHIKQKEILTKTR.A...WFSEAFGKVK...EKLKTTF.........
APOC1_URSMA/27-87                    ........APEISSTLGSIPDKLKEFGNTLEDKARAAIESIKQSDIPAKTR.N...WFSETFNKVK...EQLKTAF.........
K7ELM9_HUMAN/27-66                   ........TPDVSSAL----DKLKEFGNTLEDKARELISRIKQSELSAKMR.-...----------...-------l........
A0A5E4BPC2_MARMO/53-113              ........APDVSSTFEQIPGKLKEFGNTLEDKTREAINHIKNSDFATKTR.T...WFSETFTKVK...EKLKDTF.........
A0A0G2K9R5_RAT/27-69                 ........APDFSSAMESLPDKLKEFGNTLEDKARAAIEHIKQKEIMIKTR.-...----------...-------.........
A0A6I8R0U8_XENTR/29-84               ......sk--SFRDHFDSAGTAIKDFGA----KTKDFFKDLHNSEAMTKTR.N...WFTDLYKKIK...EKT----tgs......
A0A2I3S0Y0_PANTR/27-66               ........TPDVSSAL----DKLKEFGNTLEDKARELISRIKQNELSAKMR.-...----------...-------l........
A0A3Q3LIT6_9TELE/22-82               .......e-ETIKQRVVKISEQLSEGVKTLADKAKTGFDQLHNSDFAVSTR.N...WFQEQFDKVK...TKLGE--lt.......
A0A3Q2ECG4_CYPVA/22-82               ......dd--SIQDRLSTFRDQVTEFSKTVAEKAKTHFDTMRTSEFAESTK.N...WFTERFQQIK...QKIDE--is.......
A0A3Q3W075_MOLML/23-76               .......e-ETVGSTFTRFGDHVTDMTRGLVDRTRDAFHKIKTSDFATKTN.HylcWFNNQ-----...-------pv.......
A0A2I2Y9E5_GORGO/27-66               ........TPDVSSAL----DKLKEFGNTLEDKARELISRIKQSELSAKMR.K...----------...-------.........
A0A2K5UBW4_MACFA/27-66               ........APDVSSAL----DKLKEFGNTLEDKAWEVINRIKQSEFPAKTR.-...----------...-------l........
A0A2K5YU00_MANLE/27-66               ........APDVSSAL----DKLKEFGNTLEDKAWEVINRIKQSEFPAKTW.-...----------...-------l........
A0A2Y9GD53_NEOSC/27-87               ........APEISSTLGRIPDKLKEFGNTLEDKARAAIDSIKQSDIPAKTR.N...WFSETFNKVK...EQLKTAF.........
A0A672FCP2_SALFA/22-76               ......dd--TLEAKLNKIKDQFTEMGSNLADHLSTTFRNVQDSDTIESIK.S...WWAQQLERLK...Q------.........
A0A4W5Q185_9TELE/47-107              .......e-KTIEEHFATFGNQMKELTDDLTVKTKDMFEKIGDSEFATKTK.N...WFTEQFDKMK...AKVDETF.........
A0A672YEM5_9TELE/22-81               .......e-ETMEQKIANVGSQITEFGQQVAEQTKAALESFKNSETTQKIK.S...WADEYIEMIK...NAV----rps......
A0A2I2YNH6_GORGO/27-83               ........TPDVSSAL----DKLKEFGNTLEDKARELISRIKQSELSAKMR.D...WFSETFQKVK...EKLKID-s........
A0A3P9NB05_POERE/21-81               .......q-DDFAERFSNFGDQLTEFGKNVAEKAKTHYDTISTSEFAVSTR.N...WFTEQFQKIK...TKVNE--ma.......
A0A2K6KMS7_RHIBE/7-46                .......v-PDVSNPF----DVLEEFGKTLEDNVREVIKLITQSELPAKTR.-...----------...-------l........
APO1A_PANTR/27-83                    ........APEVSNPF----DGLEELGKTLEDNTREFINRITQSELPAKMW.D...WFSETFRKVK...EKLKID-s........
APOC1_SAIBB/31-86                    .veassgl------------DKLKEFGNNLEDKVREFFKRIKESDIPAKTR.N...WFSETLQKVK...EKLRIE-s........
APOC1_RABIT/1-28                     ........APDF-STLELIPDKLKEFGNTLEEKARMA--------------.-...----------...-------.........
A0A2K5N8J7_CERAT/27-66               ........APDVSSAL----DKLKEFGNTLEDKAWEVINRIKQSEFPAKTR.-...----------...-------l........
A0A452SDT4_URSAM/63-123              ........APEISSTLGSIPDKLKEFGNTLEDKARAAIESIKQSDIPAKTR.N...WFSETFNKVK...EQLKTAF.........
A0A3Q7TP54_URSAR/27-87               ........APEISSTLGSIPDKLKEFGNTLEDKARAAIESIKQSDIPAKTR.N...WFSETFNKVK...EQLKTAF.........
A0A498LXY1_LABRO/23-78               ........EPTLEQQFAKFQTQVKEIADDLTEKTKTTFEQIENSEFAIKTK.N...WFTEQFEKM-...-------srl......
A0A2U3VZJ4_ODORO/27-87               ........APEISSTLERIPDKLKEFGNTLEDKTRAAIESIKQSDIPAKTR.N...WFSETFKKVK...EQLKTAF.........
A0A2S3QKY3_9PROT/35-95               ........EPTLEERFAKFQTQVKEIAEDLTEKTKTTFEQLDKSEFAVKTK.S...WFNEQYEKMK...QKLSETF.........
A0A3B5Q6K8_XIPMA/78-138              ......dd--SFAERFSNFGDQITEFSKNVAEKAKTHFDTITTSEFAENTR.N...WFTEQFQKIK...SKVNE--ma.......
A0A1L8FN76_XENLA/29-88               .......s-KTIKDHLETAGTAIKDFGTKVGEKTKDFFKDLHNSEPMTKTR.N...WFSETFKKIK...EKVSS--s........
APO1A_GORGO/27-83                    ........APEVSNPF----DGLEELGKTLEDNTQELINRITQSELPAKMW.D...WFSETFRKVK...EKLKID-s........
A0A671ED92_RHIFE/25-82               .......d-PDLSSSI---PSKLKELGSALEEKVRAAIEHIKQSDFPTKTR.N...WFSETYSKVK...EKFKTTF.........
A0A5A9N2T2_9TELE/23-83               ........EPTLEQRFASFHTQVKDLADDLTQKTKNTFDQMEKSEFAVKTK.N...WFTEQFEKMK...QKMSESF.........
APO1B_MACNE/27-83                    ........APDVSSAL----DKLKEFGNTLEDKAWEVINRIKQSEFPAKTR.D...WFSETFRKVK...EKLKIN-s........
A0A2K6BA99_MACNE/27-66               ........APDVSSAL----DKLKEFGNTLEDKAWEVINRIKQSEFPAKTR.-...----------...-------l........
A0A553QTW6_9TELE/103-163             ........EPTLEQHFAKFQTQVKEIADDLAEKTKTAFQNIEQSEFGTKTR.N...WFNEQYAKLK...QKMSEGF.........
K7EPF9_HUMAN/27-66                   ........TPDVSSAL----DKLKEFGNTLEDKARELISRIKQSELSAKMR.-...----------...-------l........
APOC1_HUMAN/27-83                    ........TPDVSSAL----DKLKEFGNTLEDKARELISRIKQSELSAKMR.E...WFSETFQKVK...EKLKID-s........
#=GR APOC1_HUMAN/27-83         SS    ........XXXHHHHH----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.H...HHHHHHHHHH...HHTHTT-X........
APO1A_PONAB/27-83                    ........APDVSNPF----DGLEELGKTLEDNTREFINRITQSELPAKMW.D...WFSETFRRVK...EKLKID-s........
A0A3Q3E7A6_9LABR/23-82               .......e-ETVQQKLSNLGDQMTEMGKNLAEKAKTTFDELSNSQFASDTR.D...WFTKHIEQLK...SKF----gdv......
A0A1S3GHG3_DIPOR/27-83               ........APDFSSTL----EKVKEIGNTLENKTRTTIDRIKNSEFLAKTR.S...WISEKWDKAK...ERIRGA-f........
APO1B_MACFA/27-83                    ........APDVSSAL----DKLKEFGNTLEDKAWEVINRIKQSEFPAKTR.D...WFSETFRKVK...EKLKIN-s........
A0A671WK28_SPAAU/22-73               .......e-ETTEQTFAKFGEQMTEMGKDLAEKAKTTFENINNSEFAVTSR.-...----------...-------yiqfmeqsl
APOC1_MOUSE/27-87                    ........APDLSGTLESIPDKLKEFGNTLEDKARAAIEHIKQKEILTKTR.A...WFSEAFGKVK...EKLKTTF.........
A0A2K6QV44_RHIRO/27-66               ........APDVSSAL----DKLKEFGNTLEDKAWEVINRIKQSEFPAKTR.-...----------...-------l........
APO1B_MACMU/27-83                    ........APDVSSAL----DKLKEFGNTLEDKAWEVINRIKQSEFPAKTR.D...WFSETFRKVK...EKLKIN-s........
A0A2R9BCB5_PANPA/27-67               ........APEVSNPF----DGLEELGKTLEDNTREFINRITQSELPAKMW.-...----------...-------le.......
A0A2I3TRS5_PANTR/27-66               ........TPDVSSAL----DKLKEFGNTLEDKARELISRIKQNELSAKMR.-...----------...-------l........
A0A5J5DEI4_9PERO/22-82               .......e-ETIEQKFAAFRNQMAEIGKSLTEKAKTTLDQIQTSDLAIKSK.N...WFQEQFESLK...TKVG---eis......
A0A4W6DAT6_LATCA/22-82               ......dd--TVQEKFANFGKQLSEMSLGLAEKAKTAFEEIHQSQFATETR.S...WFDQLIEKAK...STIS---ema......
A0A3Q7U1S2_VULVU/27-87               ........ASQITRTLECIPDKLKEFGNTXEDKAWEAIESIKLSDIPAKIR.N...WFMETYNKVK...EWLKT--ny.......
A0A3Q4AWR8_MOLML/23-77               .......e-ETVGSTFTRFGDHVTDMTRGLVDRTRDAFHKIKTSDFATKTK.N...WFE-------...-------sfktrige.
F7F732_CALJA/31-69                   ....vdts-----SGF----DKLKEFGNTMEDKVREFFNRVKESDIPAKTR.-...----------...-------r........
A0A1S3RYY8_SALSA/24-84               .......e-KTIEERFTTFSNQMKELTDDLTVKTKDMFEKIGDSEFAIKTK.T...WFTEQLDKMK...AKVDETF.........
APOC1_LEPWE/27-87                    ........APEISSTLGRIPDKLKEFGNTLEDKARAAIESIKQSDIPAKTR.N...WFSETFHKVK...EQLKTAF.........
A0A2I3M1V7_PAPAN/27-66               ........APDVSSAL----DKLKEFGNTLEDKAWEVINRIKQSEFPAKTR.-...----------...-------l........
APOC1_RAT/27-87                      ........APDFSSAMESLPDKLKEFGNTLEDKARAAIEHIKQKEIMIKTR.N...WFSETLNKMK...EKLKTTF.........
A0A3Q3AYU5_KRYMA/20-79               ........AQDADSGFANFQDRLSEFGRNVAEKAKDTIDTIKNSEVAQKTQ.N...WFEEKFAKLK...THFQQ--d........
A0A2Y9TD48_PHYMC/27-87               .......g-PDINSILDHILEXVKETGNTLEEKTQDVVDYIRQTNIPAKAW.H...WLSGIFHKIE...EGLNTTS.........
A0A3Q2X0K0_HAPBU/23-83               ......dt--SFTDKFDRFGQKLTEIGQSLAEKTKTAFNDMHNSEFGTSTR.N...WFSDAFEKMK...AKFGE--ms.......
A0A2Q0E1U3_CEBCA/30-86               avdassgl------------DKLKEFGNTLENKVREFFSRIKESDIPTKTR.N...WFSETLQKVK...EKLNIE-s........
K7EJI9_HUMAN/27-66                   ........TPDVSSAL----DKLKEFGNTLEDKARELISRIKQSELSAKMR.E...----------...-------.........
A0A3B3IF59_ORYLA/20-80               .......a-QDGDQTYTQLKDQITEFGKTFAEKAKNTFETIHNSEFAETTR.N...WFTSAFDKLK...TKFEE--in.......
A0A2Y9L3B7_ENHLU/27-87               ........APEISSTFERIPDKLKEFGNTLEDKARAAIETIKQSDIPAKTR.T...WFSETYNKVK...ERLKTAF.........
F6R091_MONDO/26-86                   .......s-SSLAQSFEQFQKKVKEFTETVVEKTKAAITQIKHSDLPSKTR.T...WITENIQKVK...DKVESTF.........
A0A5F4W3B1_CALJA/31-86               ....vdts-----SGF----DKLKEFGNTMEDKVREFFNRVKESDIPAKTR.N...WFSETLQKVK...EKLGI--es.......
A0A1S3WNK4_ERIEU/27-86               ........APDFSSTLEEIQSKLKTFGSSVSEKTRAIVDKIKEKEITTKAR.N...WFLDTVTKLK...EKLNI--k........
A0A3P8W7U9_CYNSE/22-78               .......e-ETVQEKLNKFAERVADAGRTVADGARTQYDRLRNSEFATNAK.N...WFQRQVEKLQ...SK-----s........
B5XE16_SALSA/24-84                   .......e-KTIEERFTTFSNQMKELTDDLTVKTKDMFEKIGDSEFAIKTK.T...WFTEQLDKMK...AKVDETF.........
A0A674B6Z2_SALTR/24-84               .......e-KTIEERFTTFGNQMKELTDDLTVKTKDMFEKIGDSEFAIKTK.N...WFTEQLDKMK...TKVDETF.........
A0A3N0YNU0_ANAGA/23-83               ........EPTLEERFAKFQTQVKEIAEDLTEKTKTTFEQLDKSEFAVKTK.S...WFNEQYEKMK...QKLSETF.........
APO1B_PANTR/27-83                    ........TPDVSSAL----DKLKEFGNTLEDKARELISRIKQNELSAKMR.E...WFSETFQKVK...EKLKID-s........
B6S6L6_RABIT/27-86                   ........APDF-STLELIPDKLKEFGNTLEEKARMAIEHIKQSEITTKTR.N...WFSETISKVK...EKFKSTF.........
A0A485MLC3_LYNPA/27-87               ........APQISSTLELILDKLKEFGKALKDKALGSHESIKQSYIPAKTQ.N...WFSKTFNKGK...ERLKITF.........
A0A4W5MAZ8_9TELE/24-84               .......e-KNIEEHFATFGNQMKELTDDLTVKSKDIIEKIGDSEFVTKTR.T...WFTEQFDKMK...AKIDETF.........
A0A2U3VZJ8_ODORO/101-161             ........APEISSTLERIPDKLKEFGNTLEDKTRAAIESIKQSDIPAKTR.N...WFSETFKKVK...EQLKTAF.........
A0A2U3Y4E1_LEPWE/27-87               ........APEISSTLGRIPDKLKEFGNTLEDKARAAIESIKQSDIPAKTR.N...WFSETFHKVK...EQLKTAF.........
A0A4W4ELN8_ELEEL/23-72               ........EPTVEEHFANIHTKLKEFGEDLSEKAISALKKLEESELHIK--.-...----------...-------qakdikqif
A0A2K6I494_PANTR/27-84               ........APEVSNPF----DGLEELGKTLEDNTREFINRITQSELPAKMWlE...PFPGTIRKGK...EKLKID-s........
A0A667YDZ3_9TELE/19-79               ...eaqqd-----DTLANFGTKVKEVTLDMGEKVKTAFEEVHNSDFAVNTR.K...WFAGQFDA--...-------fleqyqrmt
A0A6A5FEI1_PERFL/73-132              .......e-ETIEQRFATFRDQMAEMSKNLAEKAKTTFEQFQTSDLAVNSQ.N...WFREQYESLK...AKV----gei......
APO1A_CERAT/25-81                    .......v-PDVSNPF----DVLEEFGKTLEDNVREFINLITQSELPAKTR.D...WFSETFRKVK...EKLKIN-s........
A0A402FNK0_9SAUR/82-142              ........EPTLSQKFERFQEDVQTFFDDVGEKAKGALHDLHNSEISNKTR.N...WFAEKFRKLK...ERFQTTF.........
A0A3Q1I8I3_ANATE/22-77               .......d-KTLQQRLSEFGEQIGEIGRTVAEKAKDGYQSFHNSEFVSNAR.N...WLQEQMEKVK...-------ti.......
A0A2Y9RTQ3_TRIMA/28-84               .......v-PDFSCTLERIPDKLKEFGNTLEDKAKAAIDRIKQSDIYAKTR.S...WFN----KMK...EKLKTAF.........
G3TCR3_LOXAF/27-69                   ........APDFSGTLEGIPDKLKEFGSTLENKAKKLYDRIKESDFTTKTR.-...----------...-------.........
APO1B_PONAB/27-65                    ........APDVSSAL----DKLKEFGNTLEDKAREVINRIKQSELSAKTR.-...----------...-------.........
A0A0P7YF15_SCLFO/30-85               ........EPTLQEHFTNLQQHVKDLGESFLEKAKAAIQKIQESTIATNAR.N...WLNEQMEKLM...-------pk.......
A0A2I3SWP8_PANTR/27-66               ........TPDVSSAL----DKLKEFGNTLEDKARELISRIKQNELSAKMR.K...----------...-------.........
A0A060YLA8_ONCMY/24-84               .......e-KTIEERFTTFGNQMKELTDDLTVKTKDMFEKIGDSEFATKTK.T...WFTEQFDKMK...AKVDETF.........
A0A4W4EPP7_ELEEL/23-83               ........EPTVEEHFANIHTKLKEFGEDLSEKAISALKKLEESELASKTR.S...WITENIEKLK...QKIDETF.........
APO1B_CERAT/27-83                    ........APDVSSAL----DKLKEFGNTLEDKAWEVINRIKQSEFPAKTR.D...WFSETFRKVK...EKLKIN-s........
A0A3B1J6A2_ASTMX/65-125              ........EPTIEQHFANFHTKVKEFGSDVAEKTMATIKEIEQSEFAAKTK.N...WFTEQFEKMK...KHIDETF.........
A0A3P9B4G7_9CICH/23-66               ......dt--SFTDKFDRFGQKLTEIGQSLAEKTKTAFDDIHNSEFGTRTR.-...----------...-------y........
K7ERI9_HUMAN/27-77                   ........TPDVSSAL----DKLKEFGNTLEDKARELISRIKQSELSAKMR.E...WFSETFQKVK...E------.........
APOC1_CANLF/27-87                    ........AGEISSTFERIPDKLKEFGNTLEDKARAAIESIKKSDIPAKTR.N...WFSEAFKKVK...EHLKTAF.........
A0A1U7QUM6_MESAU/27-87               ........TPDLSSAFENLPEKLKEFGNTLEDKARAAIEHIKQKEILTKTR.T...WFSETFGKLK...EKLKTTF.........
A0A671WQU2_SPAAU/22-82               .......e-ETTEQTFAKFGEQMTEMGKDLAEKAKTTFENINNSEFAVTSR.N...WFTQQLEKLK...NRVQE--is.......
A0A452SDT0_URSAM/76-136              ........APEISSTLGSIPDKLKEFGNTLEDKARAAIESIKQSDIPAKTR.N...WFSETFNKVK...EQLKTAF.........
APOC1_ODORO/27-87                    ........APEISSTLERIPDKLKEFGNTLEDKTRAAIESIKQSDIPAKTR.N...WFSETFKKVK...EQLKTAF.........
A0A5E4BLF1_MARMO/53-112              ........APDVSSTFEQIPGKLKEFGNTLEDKTREAINHIKNSDFATKT-.T...WFSETFTKVK...EKLKDTF.........
G5CBM5_HETGA/27-87                   ........APDFTSTLEGLPAKLKEFGSILEDKALAAIEHIKQSELPAKTR.N...WFSDAFSKVQ...EKFKATF.........
A0A669BT51_ORENI/23-84               ......dt--SIQERFDRFGQKLTEIGQSLAEKTKTAFQDLHNSEFGTSTR.N...WFTDAFQKMKlfmQ------kmks.....
A0A3Q7TWR0_VULVU/27-87               ........AGEISSTFERIPDKLKEFGNTLEDKARAAIESIKKSDIPAKTR.N...WFSEAFNKVK...NHLKTAF.........
G1M242_AILME/27-87                   ........APEISSTLGSIPDKLKEFGNTLEDKARAAIESIKQSDIPAKTR.N...WFSETFNKVK...ERFKTAF.........
A0A5C6ME59_9TELE/22-82               .......e-DTFMDRLGRLREHVTSSATTLLEKGKAVVEDISNSKYAVESR.T...WLQEQMERVA...NKFQE--lk.......
A0A6Q2XFS8_ESOLU/33-93               .......e-KSIEDHFTEFGAKLKEFTDGISVKTKDVVDKVGDSEFVTKTR.T...WFTEQFDKLK...TKMDETF.........
A0A087XQE1_POEFO/26-68               ......dd--SLAEKFSNFGDQITEFGKNVAEKAKTHFDTIATSEFAENTR.-...----------...-------.........
APO1A_PANPA/27-83                    ........APEVSNPF----DGLEELGKTLEDNTREFINRITQSELPAKMW.D...WFSETFRKVK...EKLKID-s........
APO1A_MACFA/25-81                    .......v-PDVSNPF----DVLEEFGKTLEDNVGEFINLITQSELPAKTR.D...WFSETFRKVK...EKLRIN-s........
H0WAV6_CAVPO/27-87                   ........APDLGSALESLPGKLKEFGSTVESKARAAIEHIKQSDFPTKTW.K...WLSKTVSKVR...EKFKATF.........
APOC1_OTOGA/27-80                    ...tmdld----------FTRHLKEFGNTMGDKAREVIDRIKQSDIPAKTR.N...WFSETFQKVK...EKLKI--.........
APO1A_MACMU/25-81                    .......v-PDVSNPF----DVLEEFGKTLEDNVGEFINLITQSELPAKTR.D...WFSETFRKVK...EKLRIN-s........
A0A2K6QV36_RHIRO/27-83               ........APDVSSAL----DKLKEFGNTLEDKAWEVINRIKQSEFPAKTR.D...WFSETFRKVK...EKLKIN-s........
A0A4D9DJX7_9SAUR/41-100              ........EPTLTQKFEKFQNKLQAFADSIADKTKAAFQELHHSEFSEKTR.N...WFSEQFQKIK...EKFSR--d........
A0A5S6DCB0_CANLF/27-70               ........AGEISSTFERIPDKLKEFGNTLEDKARAAIESIKKSDIPAKTR.-...----------...-------l........
A0A674DB74_SALTR/24-84               .......e-KTIEEHFTTFGNQMKELSDDLTVKTKDIVEKIGDSEFVTKTR.T...WFTEQLDKMK...AKIDETF.........
A0A2Y9E9C7_TRIMA/27-83               ........APDFSSTLERIPDKLKEFGNTLKDKAKAAFDRIKQSDIYAKTG.S...WFN----KMK...EKLKTAF.........
E9QFX0_DANRE/23-83                   ........EPTLEQHFTKFGTQMKEIAEDLADKTKTAFQNIEQSELGTKTR.N...WFNDQYEKLK...QKMTETF.........
A0A1A6FVC0_NEOLE/27-87               ........TPDLASTFENLPDKLKEFGSALEDKTRAAIEHIKQKGILTKTR.T...WFSETFDKVK...EKFKTTF.........
A0A2K5TIZ9_GORGO/27-66               ........TPDVSSAL----DKLKEFGNTLEDKARELISRIKQSELSAKMR.-...----------...-------l........
A0A3Q0FT94_ALLSI/212-272             ........EPTLMQKLEQFKENVKDFADTIGEKTKAALQELRDSEFSTKTR.N...WFSEHFKKVK...EKLKDTF.........
A0A5N5Q534_PANHP/77-137              ........EPTIEQHFANFHAKLQEFGSDLTEKTAKALKEFETSEFAAKTK.N...WFTEQFEKVR...QKFDETF.........
G3NGS3_GASAC/26-86                   ........EQTVEQRFNRFGEQVAEVSKGLAEKAKTTFEEISTSQFAEDTR.N...WFQTQFESLK...AKLSPL-t........
A0A2Y9NT54_DELLE/27-87               .......g-PDINSILGHILEXVKEFGNTLEEKTWGVVDYIKQTNIPPKAW.H...WLSGIFHKIE...EGLNTTS.........
APO1B_PAPAN/27-83                    ........APDVSSAL----DKLKEFGNTLEDKAWEVINRIKQSEFPAKTR.D...WFSETFRKVK...EKLKIN-s........
E9QDI1_DANRE/24-84                   ........EPTLEQHFTKFGTQMKEIAEDLADKTKTAFQNIEQSELGTKTR.N...WFNDQYEKLK...QKMTETF.........
A0A1S3N6L4_SALSA/24-84               .......e-KTIEEHFTNFGNQMKELSDDLTVKTKDIVEKIGDSEFVTKTR.T...WFTEQLDKMK...AKIDETF.........
A0A669DZ96_ORENI/23-73               ......dt--SIQERFDRFGQKLTEIGQSLAEKTKTAFQDLHNSEFGTSTR.-...----------...-------yshlqeis.
A0A315VB23_GAMAF/22-76               ......dd--SLAERFSNFGDQITEFSKNVAEKAKTHFDTITTSEFAENTR.N...WFTEQFQKIK...Q------.........
M3Y497_MUSPF/27-87                   ........APEISSTFERIPDKLKEFGNTLEDKARAAIETIKQSDIPAKTR.N...WFSETYSKLK...ERLKTAF.........
#=GC SS_cons                         ........XXXHHHHH----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.H...HHHHHHHHHH...HHTHTT-X........
#=GC seq_cons                        ........tPslssshtph.D+LKEFGsTLp-Ks+sslccI+pSEhssKTR.s...WFsEphpKlK...pphp............
//
DBGET integrated database retrieval system