GenomeNet

Database: Pfam
Entry: BID
LinkDB: BID
Original site: BID 
#=GF ID   BID
#=GF AC   PF06393.11
#=GF DE   BH3 interacting domain (BID)
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   Pfam-B_16321 (release 9.0)
#=GF GA   25.00 25.00;
#=GF TC   25.60 35.90;
#=GF NC   23.50 24.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   BH3_interacting-domain_death_agonist
#=GF RN   [1]
#=GF RM   10089878
#=GF RT   Solution structure of the proapoptotic molecule BID: a
#=GF RT   structural basis for apoptotic agonists and antagonists. 
#=GF RA   McDonnell JM, Fushman D, Milliman CL, Korsmeyer SJ, Cowburn D; 
#=GF RL   Cell 1999;96:625-634.
#=GF DR   INTERPRO; IPR010479;
#=GF DR   SCOP; 1ddb; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   BID is a member of the BCL-2 superfamily of proteins are  key
#=GF CC   regulators of programmed cell death, hence this family is
#=GF CC   related to Pfam:PF00452 .  BID is a pro-apoptotic member of the
#=GF CC   Bcl-2 superfamily and as such posses the ability to target
#=GF CC   intracellular membranes and contains the BH3 death domain. The
#=GF CC   activity of BID is regulated by a Caspase 8-mediated cleavage
#=GF CC   event, exposing  the BH3 domain and significantly changing the
#=GF CC   surface  charge and hydrophobicity, which causes a change of 
#=GF CC   cellular localisation [1].
#=GF SQ   128
#=GS A0A1D5QI48_MACMU/3-104      AC A0A1D5QI48.1
#=GS A0A218V0Q7_9PASE/3-181      AC A0A218V0Q7.1
#=GS G1NL76_MELGA/4-193          AC G1NL76.2
#=GS A0A0P7VIW7_9TELE/113-226    AC A0A0P7VIW7.1
#=GS A0A2I2ZUR1_GORGO/3-91       AC A0A2I2ZUR1.1
#=GS W5JYR5_ASTMX/7-201          AC W5JYR5.1
#=GS W5PVK6_SHEEP/4-189          AC W5PVK6.1
#=GS F7IH28_CALJA/1-96           AC F7IH28.1
#=GS Q05KI5_BOVIN/3-73           AC Q05KI5.1
#=GS G3W5W2_SARHA/3-194          AC G3W5W2.1
#=GS F7A8I6_HORSE/1-187          AC F7A8I6.1
#=GS A0A1U7UWY1_TARSY/3-192      AC A0A1U7UWY1.1
#=GS A0A091E645_FUKDA/33-223     AC A0A091E645.1
#=GS B2ZP78_HUMAN/3-91           AC B2ZP78.1
#=GS A0A091UT25_PHALP/1-182      AC A0A091UT25.1
#=GS Q1LX52_DANRE/6-187          AC Q1LX52.1
#=GS A0A093HWC3_STRCA/3-188      AC A0A093HWC3.1
#=GS H0W5F0_CAVPO/1-187          AC H0W5F0.2
#=GS Q05KI5_BOVIN/64-143         AC Q05KI5.1
#=GS G1PYL8_MYOLU/1-188          AC G1PYL8.1
#=GS A0A151NIJ8_ALLMI/4-137      AC A0A151NIJ8.1
#=GS A0A093J8C7_EURHL/1-176      AC A0A093J8C7.1
#=GS A0A1U8CVY3_MESAU/111-169    AC A0A1U8CVY3.1
#=GS A0A2I3LMR4_PAPAN/3-101      AC A0A2I3LMR4.1
#=GS V8P747_OPHHA/84-255         AC V8P747.1
#=GS A0A091FUS3_9AVES/2-182      AC A0A091FUS3.1
#=GS G3W5W1_SARHA/1-185          AC G3W5W1.1
#=GS G3R4T6_GORGO/3-192          AC G3R4T6.2
#=GS A0A099ZHG9_TINGU/2-190      AC A0A099ZHG9.1
#=GS K7G3T4_PELSI/1-184          AC K7G3T4.1
#=GS A0A091PMQ4_HALAL/1-184      AC A0A091PMQ4.1
#=GS A0A1A6HG53_NEOLE/3-193      AC A0A1A6HG53.1
#=GS A0A091MXU8_9PASS/1-181      AC A0A091MXU8.1
#=GS H2P4Y4_PONAB/101-224        AC H2P4Y4.1
#=GS A0A1V4K844_PATFA/119-309    AC A0A1V4K844.1
#=GS A0A091K5T8_COLST/1-179      AC A0A091K5T8.1
#=GS A0A0Q3UPY0_AMAAE/2215-2401  AC A0A0Q3UPY0.1
#=GS G7PH70_MACFA/45-234         AC G7PH70.1
#=GS BID_CHICK/3-193             AC Q8JGM8.2
#=GS A0A1U8CVY3_MESAU/1-71       AC A0A1U8CVY3.1
#=GS W5NIN1_LEPOC/1-185          AC W5NIN1.1
#=GS A0A091KR22_9GRUI/1-183      AC A0A091KR22.1
#=GS A0A2I3SGG1_PANTR/3-91       AC A0A2I3SGG1.1
#=GS A0A1D5P8E8_CHICK/4-193      AC A0A1D5P8E8.1
#=GS A0A1U8CZB5_ALLSI/4-191      AC A0A1U8CZB5.1
#=GS U3IN21_ANAPL/3-193          AC U3IN21.1
#=GS G3HQ86_CRIGR/3-191          AC G3HQ86.1
#=GS A0A091INR9_EGRGA/1-184      AC A0A091INR9.1
#=GS A0A091ECP1_CORBR/1-179      AC A0A091ECP1.1
#=GS H2QL73_PANTR/49-238         AC H2QL73.1
#=GS A0A1S3WES5_ERIEU/11-228     AC A0A1S3WES5.1
#=GS A0A093RUG0_9PASS/54-207     AC A0A093RUG0.1
#=GS A0A2D0QTM1_ICTPU/3-197      AC A0A2D0QTM1.1
#=GS A0A093PP76_PHACA/2-182      AC A0A093PP76.1
#=GS S9XDC5_CAMFR/168-354        AC S9XDC5.1
#=GS A0A091WNX5_OPIHO/1-184      AC A0A091WNX5.1
#=GS A0A2K5LVW2_CERAT/3-192      AC A0A2K5LVW2.1
#=GS A0A1S3FSZ5_DIPOR/3-194      AC A0A1S3FSZ5.1
#=GS G1TB99_RABIT/12-207         AC G1TB99.1
#=GS A0A2K5J9S2_COLAP/3-95       AC A0A2K5J9S2.1
#=GS F7DQE5_ORNAN/1-96           AC F7DQE5.1
#=GS A0A0D9RP74_CHLSB/45-234     AC A0A0D9RP74.1
#=GS A0A0A0A4E6_CHAVO/1-184      AC A0A0A0A4E6.1
#=GS F7CU55_MONDO/68-258         AC F7CU55.2
#=GS H2P3K4_PONAB/1-96           AC H2P3K4.2
#=GS G1KMF0_ANOCA/7-186          AC G1KMF0.1
#=GS A0A091N4S2_CARIC/1-184      AC A0A091N4S2.1
#=GS F7ACD0_HORSE/1-187          AC F7ACD0.1
#=GS A0A2I3GK37_NOMLE/3-84       AC A0A2I3GK37.1
#=GS Q17QH5_BOVIN/3-190          AC Q17QH5.1
#=GS A0A091UUF5_PHORB/1-184      AC A0A091UUF5.1
#=GS A0A091GP84_BUCRH/1-180      AC A0A091GP84.1
#=GS BID_HUMAN/3-192             AC P55957.1
#=GS BID_HUMAN/3-192             DR PDB; 2BID A; 5-194;
#=GS BID_HUMAN/3-192             DR PDB; 5AJJ B; 81-109;
#=GS BID_HUMAN/3-192             DR PDB; 4ZIG B; 79-98;
#=GS BID_HUMAN/3-192             DR PDB; 1ZY3 B; 201-220;
#=GS BID_HUMAN/3-192             DR PDB; 4ZEQ B; 79-104;
#=GS BID_HUMAN/3-192             DR PDB; 4QVE B; 77-104;
#=GS BID_HUMAN/3-192             DR PDB; 2KBW B; 76-106;
#=GS BID_HUMAN/3-192             DR PDB; 4ZII C; 76-99;
#=GS BID_HUMAN/3-192             DR PDB; 5C3F B; 80-101;
#=GS BID_HUMAN/3-192             DR PDB; 2M5B B; 80-101;
#=GS BID_HUMAN/3-192             DR PDB; 4BD2 C; 76-105;
#=GS BID_HUMAN/3-192             DR PDB; 2M5I A; 61-192;
#=GS F7DQF1_ORNAN/9-135          AC F7DQF1.1
#=GS A0A094L7K7_ANTCR/1-184      AC A0A094L7K7.1
#=GS F7IH59_CALJA/46-232         AC F7IH59.1
#=GS F7DU73_XENTR/4-185          AC F7DU73.1
#=GS A0A1D5QH89_MACMU/3-192      AC A0A1D5QH89.1
#=GS A0A287BP00_PIG/1-186        AC A0A287BP00.1
#=GS A0A2I0MKV4_COLLI/2-191      AC A0A2I0MKV4.1
#=GS G1MGI0_AILME/3-192          AC G1MGI0.1
#=GS I3N331_ICTTR/3-192          AC I3N331.2
#=GS A0A1S3KQ61_SALSA/2-196      AC A0A1S3KQ61.1
#=GS A0A287AYM3_PIG/3-189        AC A0A287AYM3.1
#=GS A0A087R1G3_APTFO/1-183      AC A0A087R1G3.1
#=GS A0A093CDL5_TAUER/1-183      AC A0A093CDL5.1
#=GS Q56VD1_XENLA/4-183          AC Q56VD1.1
#=GS L5MJN0_MYODS/57-247         AC L5MJN0.1
#=GS F6WQU1_MACMU/32-221         AC F6WQU1.2
#=GS A0A093IUQ8_FULGA/1-116      AC A0A093IUQ8.1
#=GS M7ARC5_CHEMY/27-215         AC M7ARC5.1
#=GS A0A2K5J9S8_COLAP/63-252     AC A0A2K5J9S8.1
#=GS A0A140T8G9_CHICK/3-193      AC A0A140T8G9.1
#=GS U3K4T9_FICAL/2-184          AC U3K4T9.1
#=GS G3T1D2_LOXAF/1-192          AC G3T1D2.1
#=GS A0A091VX00_NIPNI/1-184      AC A0A091VX00.1
#=GS A0A226PLU2_COLVI/5-193      AC A0A226PLU2.1
#=GS BID_PIG/3-189               AC Q4JHS0.1
#=GS BID_PIG/3-189               DR PDB; 5UA4 B; 26-57;
#=GS M3WEH6_FELCA/3-193          AC M3WEH6.2
#=GS F7IEQ7_CALJA/1-96           AC F7IEQ7.1
#=GS A0A2K5LVY0_CERAT/3-104      AC A0A2K5LVY0.1
#=GS A0A087VAW2_BALRE/1-182      AC A0A087VAW2.1
#=GS G5BWN8_HETGA/3-193          AC G5BWN8.1
#=GS Q05KI6_BOVIN/3-190          AC Q05KI6.1
#=GS A0A2K5J9S4_COLAP/3-192      AC A0A2K5J9S4.1
#=GS A0A2K5LVW4_CERAT/52-241     AC A0A2K5LVW4.1
#=GS F7H9R6_MACMU/1-93           AC F7H9R6.2
#=GS A0A226N1M7_CALSU/23-212     AC A0A226N1M7.1
#=GS F1Q0Y3_CANLF/12-203         AC F1Q0Y3.2
#=GS H0ZQI0_TAEGU/1-140          AC H0ZQI0.1
#=GS L5JTG3_PTEAL/77-267         AC L5JTG3.1
#=GS A0A093PAB0_PYGAD/1-183      AC A0A093PAB0.1
#=GS A0A091U308_9AVES/1-118      AC A0A091U308.1
#=GS A0A093GWD1_DRYPU/1-184      AC A0A093GWD1.1
#=GS A0A091S1P2_NESNO/1-181      AC A0A091S1P2.1
#=GS H0WLJ8_OTOGA/1-198          AC H0WLJ8.1
#=GS A0A091HJX1_CALAN/1-115      AC A0A091HJX1.1
#=GS A0A091PDZ4_LEPDC/1-183      AC A0A091PDZ4.1
#=GS A0A096NVY7_PAPAN/52-241     AC A0A096NVY7.2
#=GS A0A2I3GZZ6_NOMLE/22-211     AC A0A2I3GZZ6.1
#=GS A0A094NRU2_9AVES/1-184      AC A0A094NRU2.1
#=GS G3UR49_MELGA/3-196          AC G3UR49.1
#=GS D3Z463_MOUSE/3-52           AC D3Z463.1
#=GS BID_MOUSE/3-192             AC P70444.2
#=GS BID_MOUSE/3-192             DR PDB; 1DDB A; 3-192;
#=GS BID_MOUSE/3-192             DR PDB; 2VOI B; 78-101;
#=GS BID_RAT/3-193               AC Q9JLT6.2
#=GS L7N431_XENTR/5-185          AC L7N431.1
#=GS A0A2D0QVL4_ICTPU/11-208     AC A0A2D0QVL4.1
#=GS A0A1L8GQT1_XENLA/4-183      AC A0A1L8GQT1.1
A0A1D5QI48_MACMU/3-104                 .................CEVSNGSGLRDECVTNLLVFGFLQ..S..CS..DN.SFRRELDALGRE..........................LP.V...P.A.A..Q.W...E...A.......Y-..............D.ELQTDGNRSSH......S.RMG...R.IE.......AG...VSD..N.........--..------------------..-..-----------------------------------..-....-....--...-----------------------------------------------------ntasveeeteaagsvvvelgrhgaa
A0A218V0Q7_9PASE/3-181                 ...........qingpl------------QMEHALLFTFLE..V..SS..DC.NFKDQLHSLQSQ..........................Q-.-...I.M.L..C.Q...G...N.......DD..............D.ELQTDGNRSGH......F.RNG...L.P-.......--...-QT..N.........EE..VIRIIAAQLAEIGDQFDR..E..IQERVVNGLAQHFLNENLSYEEIIQHMNRAVRELT..R....A....IP...ADMEQEKAMLVLTMVLTRRIVNSVPSLLHRVITTTLNYMNQQFHNYILEML--ge.......................
G1NL76_MELGA/4-193                     ............diysd-----GS----DHMERMLLFAFLA..E..SS..GC.EFREQLPFLQSRg.......................llCA.V...K.G.V..Q.S...Y...D.......SD..............G.ELQTDGNRSGH......L.QNG...E.LV.......LD...PEV..N.........EE..IVRTIAAQLAEIGDQLDK..Q..IKAKVVNDLVQHFLNENLPREEITRCLSQAVEGLA..R....A....VP...SDLEQEKAMLVLAMLLTKKVANQVPSLLQRVFSTTVNYISQHLHNYIVRMLRE.........................
A0A0P7VIW7_9TELE/113-226               ........lsgrtgdrv------------------------..-..--..--.------------..........................--.-...-.-.-..-.-...-...-.......--..............-.-----------......-.---...-.--.......--...---..D.........PA..VLRAVAEELVRIADQLEN..R..VVSRSVERLMERLQG--APNQSWKDYLSEEVMIML..HgslgP....EL...NQLPMERMLLALTFTLVKGVCERAPRFLRGLFHAAVQYVD-------------gi.......................
A0A2I2ZUR1_GORGO/3-91                  .................CEVNNGSGLRDECITNLLVFGFLQ..S..CS..DN.SFRRELDALGHE..........................LP.V...L.A.P..Q.W...E...G.......Y-..............D.ELQTDGNRSSH......S.RLG...R.IE.......AG...ASD..N.........N-..------------------..-..-----------------------------------..-....-....--...-----------------------------------------------------tasaeeeteaa..............
W5JYR5_ASTMX/7-201                     .........ninafsqp---------------SILFLTFLQ..Q..TPshNP.EFKRELQLLTCD..........................MA.L...Q.A.D..Q.CvysG...E.......MDysdhsmidpniecdG.ELEADGHGLSIq...rnL.LQDilpQ.AH.......LG...LPV..N.........NE..VIREVAAELITIADDLNN..T..IMSRAADSLTSELRR-TSSMQTWPALLRRSVTELI..N....C....VP...G-AHNEQVTMALTFSLVKAVCERAPPLLRGLFSVLMQYI--------------yp.......................
W5PVK6_SHEEP/4-189                     ................s-QVSNGPGLGDERTTSLLLLGFLQ..S..CP..NS.CFQRELEVLGHE..........................FS.G...H.L.F..-.-...-...-.......YD..............D.ELQTDGNRSSY......F.SV-...A.AE.......TD...SER..Q.........EE..AVREVARQLAQIGDRLEG..S..IHPGMVASLVSRFSVRSLSEEDRRQCLMDALEQLM..R....T....CP...ADVDHEKTQLLLTMLLAKKIADHSPALLRDVFRTTVTFINQNLLASVRNLVR-s........................
F7IH28_CALJA/1-96                      .................------------------------..-..--..--.------------..........................--.-...-.-.-..-.-...-...-.......--..............-.-----------......-.---...-.--.......--...---..-.........--..---------------MDR..S..IPLDLVDRLALQLRNACRSEEDRRRDLASALEQLL..Q....A....HP...TDMDKEKTMLVLALLLAKKVADHTPSLLRDVFRTTVNFINQNLRAYVRSLTRN.........................
Q05KI5_BOVIN/3-73                      ................l-KVSNGPGPGDERTTSLLLLGFLQ..S..CP..HS.CFQRELEALGHE..........................LP.G...H.L.F..-.-...-...-.......HD..............D.ELQTDGNRCSH......FpLAA...E.AE.......T-...---..-.........--..------------------..-..-----------------------------------..-....-....--...-----------------------------------------------------d........................
G3W5W2_SARHA/3-194                     ........eiknffdpe---------NDNRQTSLLLYNFLQ..S..SG..NN.LFQTELKELDSE..........................LA.Vf.gS.R.N..G.C...S...E.......QD..............Y.ELQTDGNRCYF......D.MSR...E.EF.......SD...SEN..Q.........E-..IIQRIATHLAQIGDNIES..S..IQPSLVDNLIQQFRIINLSAEDKRRYLDAAMQQMM..Q....T....IP...LDLEQEKAQLLLAMLLAKKVMTHAPSLFRSIFYITVDYMNQNLITYIRNLVRN.........................
F7A8I6_HORSE/1-187                     .................--VSNGSGLQDEHITHLLVFSFLQ..N..CS..KR.HFYKELEVLGHE..........................LP.V...Q.A.Y..L.W...E...D.......H-..............D.ELQTDGNRCSH......F.V-A...R.AE.......AD...SES..Q.........EE..IIQHIARQLAQIGDRMDD..S..IHPRLVNNLAMQFMNVNLSEEDRRQCLTSALEQVM..Q....T....YP...KDMEKEKTMLMLSMLLAKKVANHTPSLLRDVFRTTVNFINQNLLTYVRNLVRN.........................
A0A1U7UWY1_TARSY/3-192                 ................s-EVSNGSGLRDAYVTDLLVFGFLQ..N..CS..NE.SFHKELEVLGHE..........................LP.V...R.A.H..L.W...E...D.......RD..............D.ELQTDGNRASR......-.HGD...R.VE.......AD...SES..Q.........EE..VIQNIARHLARIGDSMDR..G..IPPRLVHNLAAQLGDGRLSEEDRRRDLTAALDQLM..E....T....HP...IDMEKEKAMLMLALLLAKKVADHTPALLRDVFRTTVNFINQNLLAYVRSLARN.........................
A0A091E645_FUKDA/33-223                ................t-TVGNGAGLRDESIANLLVFSFLH..A..HN..NC.NFHKELEALGQE..........................LP.V...G.V.C..L.E...A...D.......HD..............D.ELQTDGNRASR.....lL.YGG...R.RE.......GD...SEN..Q.........E-..VIHSIACHLAEIGDELDR..S..IHPGLVSQLAMHFRNPSLSEEDRRHYLAAAVEKAM..Q....T....YA...TDMEQEKARLILAMLLVRKVADHTPSLLRGIFHTTVNFINQNLLTYMRDLIRN.........................
B2ZP78_HUMAN/3-91                      .................CEVNNGSSLRDECITNLLVFGFLQ..S..CS..DN.SFRRELDALGHE..........................LP.V...L.A.P..Q.W...E...G.......Y-..............D.ELQTDGNRSSH......S.RLG...R.IE.......AG...ASD..N.........N-..------------------..-..-----------------------------------..-....-....--...-----------------------------------------------------tasaeeeteaa..............
A0A091UT25_PHALP/1-182                 .............ngsv------------QMECALLYTFLE..V..SS..DC.KFREQLHSLQSQ..........................GPfL...R.G.S..Y.Y...Y...D.......DE..............V.ELQTDGNRSGH......L.QNG...E.LV.......FD...PQV..N.........EE..VVRIIAAQLAEIGDQFDK..E..IKARVVNDLVQHFLNENLSGEEITRRMSEAVEGLA..R....A....IP...SDMEQEKAMLVLAMVLTKKIANTMPSLLQRVFSTTVNYISQQLHNYIVRMV--.........................
Q1LX52_DANRE/6-187                     ..........nfdhiph--------------TSLVLLSFLD..Q..-K..DC.QNGESGRVFDYR..........................ED.N...L.S.T..N.H...I...D.......SD..............G.DIETDGQSPPAty.rdlL.HEL...Q.HE.......VQpglSVN..A.........EEarAAREMAAELIRIADLLEQ..S..VLSQAAESLTKKLRS--SQEQVWASHLSKGVQTLL..Q....H....VAa.aKEFKKELVEMAFTFMLMKTVCERTPDFLFGLYGTVVQFFG-------------sn.......................
A0A093HWC3_STRCA/3-188                 .............hsyg----------STQMERILLYNFLQ..S..SS..NC.EFGDQLQALQSQg.......................ivPS.V...R.H.F..C.C...Y...D.......DE..............G.ELQTDGNRSGH......L.QNG...E.LV.......FD...PEV..N.........EE..ILQMIGAQLAEIGDQLDR..E..IQAKVVNDLVQHFLNENVSREEITQYLSQAVEGLA..R....A....IP...SDMEQEKALLVLAMVLTKKIANRVPSLLHRVFSTTVNYISQHLHTYIVRMV--.........................
H0W5F0_CAVPO/1-187                     .................--VGNGAGTRGELVTDLLVFGFLC..S..RD..NS.NFHSELKALGQE..........................LP.G...R.P.E..V.-...-...D.......HD..............D.ELQTDGNRLSH......F.HGG...R.RE.......AD...SES..Q.........EE..LIQHIASQLALIGDEMEH..K..IQASVVHQLSTQLRDSSLTPEGRRHCLAATLGEVM..Q....T....CP...ADVEQEKAVLIMTMLLARKVADHTPRLFRVVYDTVVDFINQNLLTYVRDLVRN.........................
Q05KI5_BOVIN/64-143                    ............fplaa------------------------..-..--..--.------------..........................--.-...-.-.-..-.-...-...-.......--..............-.-----------......-.---...-.--.......--...---..-.........--..------------------..-..-----------------EAETDRRQCLAAALEQLM..Q....T....CP...PDVDHEKTQLLLTMLLAKKIADHSPALLRDVFHTTVTFINQNLLAYVRNLVRN.........................
G1PYL8_MYOLU/1-188                     .................---SNGSCLQDERITDLLVFGFLQ..N..CS..NY.NFHKELQVLGHD..........................LS.V...P.A.C..L.W...E...N.......HD..............D.ELQTDGSQYSH......F.VLE...S.RE.......TD...SES..Q.........DE..IIQNIARQLAHIGDRMDR..S..IPPRLVNHLAIQFMNGNLSEEDRRECLAAALEQVM..H....T....YP...KDMEKEKTMLMLTMLLAKKVADHTPSLLHDVFRTTVNVINQNLLTYVRNLVRN.........................
A0A151NIJ8_ALLMI/4-137                 .........gtysdgfs------------QLESLLLYSFLD..N..SQ..DC.AFKEKLQTLSCRht.....................pqcVP.H...R.R.D..F.H...S..fS.......DD..............G.ELQTDGNRSGH......F.QNG...E.--.......PG...SET..G.........E-..IYRIIGAQLAEIGDQLAA..E..MQAGPVDDLVQQFLNANLSSEEITRCLSQMVEQ--..-....-....--...-----------------------------------------------------pkk......................
A0A093J8C7_EURHL/1-176                 ..............gsv------------QMESALLYTFLE..A..SS..DC.KFRQQLRSLQSQgi......................gpLV.A...G.R.Y..C.-...-...-.......YD..............DwELQTDGNRSGH......M.QNG...D.LA.......FG...PEV..N.........EE..VVRIIAAQLAEIGDQFDK..E..IKARVVNDLVQHFLNENLSREEI------TLEGLV..Q....A....MP...SDMEREKAMLVLAMVLTKKIANTVPSLLQRVFSTTVNYINQQLHNYVVRMV--.........................
A0A1U8CVY3_MESAU/111-169               ..............tqg------------------------..-..--..--.------------..........................--.-...-.-.-..-.-...-...-.......--..............-.----------H......L.RLV...P.TR.......AH...SES..Q.........ED..IIQRIAHQLVQVGDELDH..S..IQPTLVRQLAAQFMNVSLSEE--------------..-....-....--...-----------------------------------------------------.........................
A0A2I3LMR4_PAPAN/3-101                 .................CEVSNGSGLRDECVTNLLVFGFLQ..S..CS..DN.SFRRELDALGRE..........................LP.V...P.A.A..Q.W...E...A.......Y-..............D.ELQTDGNRSSH......S.RMG...R.IE.......AG...ASD..N.........N-..------------------..-..-----------------------------------..-....-....--...-----------------------------------------------------tasveeeteaagsvvvelgrh....
V8P747_OPHHA/84-255                    .........pgdhydsi------------EVAGIVLYSFLE..N..SS..DI.TFASTLCSLKQQ..........................LL.A...P.K.Q..P.S...V...Y.......DD..............G.ELQTDGNNFGR......-.---...-.VE.......D-...---..-.........--..--RVLGARLAVIGDKLAA..E..IEHPFVHNLAQQFMVENVSSQVITQHLSEAVRNVV..A....R....MP...PEMEQEKAMLVAAMILAKKVANVVPALLQQVFNTTVNYINQNLHDYS------almhe....................
A0A091FUS3_9AVES/2-182                 ..............gsv------------QMECALLYSFLE..V..SP..DC.KFKEQLHILQSQg........................iMP.-...C.L.R..G.S...Y...D.......AE..............L.ELQTDGNRSGH......L.QNG...E.LG.......YG...PEV..D.........EE..VVRIIAAQLAEIGDQFDK..E..IKARVVNDLVQHFLNENLSREEITRRMSEAVEGLA..R....A....IP...SDMEREKAMLVLAMVLTKKIANTMPSLLQRVFSTTVNYISQHLHNYIVRMV--.........................
G3W5W1_SARHA/1-185                     ...............md---------QDNRQTSLLLYNFLQ..S..SG..NN.LFQTELKELDSE..........................LA.Vf.gS.R.N..G.C...S...E.......QD..............Y.ELQTDGNRCYF......D.MSR...E.EF.......SD...SEN..Q.........E-..IIQRIATHLAQIGDNIES..S..IQPSLVDNLIQQFRIINLSAEDKRRYLDAAMQQMM..Q....T....IP...LDLEQEKAQLLLAMLLAKKVMTHAPSLFRSIFYITVDYMNQNLITYIRNLVRN.........................
G3R4T6_GORGO/3-192                     .................CEVNNGSGLRDECITNLLVFGFLQ..S..CS..DN.SFRRELDALGHE..........................LP.V...L.A.P..Q.W...E...G.......Y-..............D.ELQTDGNRSSH......S.RLG...R.IE.......AD...SES..Q.........ED..IIRNIARHLAQVGDSMDR..S..IPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLL..Q....A....YP...RDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYVRSLARN.........................
A0A099ZHG9_TINGU/2-190                 ............ihsdg------S----SRMERILLYSFLQ..S..SS..NC.EFRDQLQTLQGQw........................iFP.V..aK.Q.V..C.H...Y...D.......DD..............G.DLQTDGNRSGH......L.QNG...E.LV.......LA...AEDmgN.........EE..IFRIIGAQLAEIGDQLDK..E..IQARVVNDLVQHFLNENLSREEITRCLSQAVEGLA..R....A....IP...SDMEQEKALLVLAMVLTKKVANRVPSLLQRIFSTTVNYINQHLHTYIVRMV--.........................
K7G3T4_PELSI/1-184                     ..............shg----------DVQVERILVYSFLQ..N..CH..NC.AFREELDSLKSQ..........................VI.VprpK.S.F..L.H...D...E.......FD.............dG.ELQTDGNRSGR......F.QNG...D.LE.......LG...SS-..V.........ED..IFQVIGAQLAQIGDQVAH..E..IHPAVVNDLLQQFVNENMSREEIMRRLSDTVEELM..R....T....VP...LEMEREKAMLVLAMVLARTVTNKMPSLLQRVFNTTVNYISQNLHNYVMNM---.........................
A0A091PMQ4_HALAL/1-184                 ..............ngs-----------VQMERVLLYTFLE..V..SS..DC.KFREQLHSLQSQg........................iVP.F...P.KgS..Y.G...Y...D.......DE..............V.ELQTDGNRSGH......L.QNG...E.LV.......FD...PEV..N.........EE..VIRIIAAQLAEIGDQFDK..E..IKARVVNDLAQHFLNENLSGEEITQRMSEAVEGLA..R....A....IP...SDMEQEKAMLVLAMVLTKKIANTMPSLLQRVFSTTVNYISQQLHNYIVRMV--.........................
A0A1A6HG53_NEOLE/3-193                 ................s-QVSNGSGLEAEHIIDLLVFGFLQ..S..A-..KD.NFHQELEALSQE..........................LP.V...E.V.Y..P.D...T...D.......FE..............D.ELQTDGSRASR.....sF.YHG...R.IE.......PD...SES..Q.........EE..IIQNIARHLAQVGDEMDH..S..IQPTLVRHLAVQFMNVSLSEEDRRNCLAKALDEVK..T....A....FP...RDMENEKAMLIMTLLLAKNVASHAPSLLPAVFRTTVNFINQNLXAYVRNLVRN.........................
A0A091MXU8_9PASS/1-181                 ..............ngs-----------LQMESALLYAFLD..V..SS..DC.KFKQQLPSLQSH..........................VI.M...S.R.Q..M.Y...C...E.......DD..............F.ELQTDGNRSGH......L.QSN...E.GV.......YE...PPV..N.........ED..VVRIIAAQLAEIGDQFDK..E..IQGQVVSDLARHFLNENLSREEIILHMSNTVKKLV..Q....A....IP...SDMEQEKAMLVLAMVLTKKIVNTTPSLLQRVFSTAVNYINQQFHNHIAEMV--.........................
H2P4Y4_PONAB/101-224                   .............plpe------------------------..-..--..--.------------..........................--.-...-.-.-..-.-...-...-.......--..............-.-----------......-.---...-.-H.......TD...SES..Q.........ED..IIRNIARHLAQVGDSMDR..S..IPPGLVNGLALQLRNTSQSEEDRNRDLATALEQLL..Q....A....YP...TDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYVRSLARN.........................
A0A1V4K844_PATFA/119-309               ............meqvn-----GS----LQMESVLLYSFLD..V..SP..DC.MFREQLHSLQSQg........................iVP.V..lQ.G.K..Y.C...Y...D.......DE..............M.ELQTDGNRSGH.....lL.QNG...E.PV.......FE...PQV..D.........EE..VVRLIAAQLAEIGDQFDR..E..IKTRLVNDLVQQFLNENLPGEVITRRMSEAVEGLV..R....A....LP...PDMEQEKATLVLAMVLTKKIVNTVPSLLPRVFRTTVNYINQHLHNYIVRMVR-g........................
A0A091K5T8_COLST/1-179                 ..............ngs-----------VQVEHMLLYTFLE..V..SS..DC.KFKEQLHSLQSQ..........................RI.V...E.L.C..-.-...Y...D.......EE..............M.ELQTDGNRSGH......L.QNG...E.PM.......SD...PEV..N.........EA..VIRIIAAQLAQIGDQFDN..K..IRARVVNDLVQHFLNENLSAEEITRRMSEAVEGLA..R....A....IP...LDMEQEKVTLVLAMVLTKKIANTMPSLLHRVFSTTVNYISQQLHNYIVRMV--.........................
A0A0Q3UPY0_AMAAE/2215-2401             ..........eeeings-----------VQMEHALLYTFLE..I..SP..DC.KFREQLHSLQSK..........................CF.Q...W.Q.Y..D.Y...S...Y.......DD..............A.ELQTDGNQSER......M.QNG...X.PV.......FD...PRV..H.........DE..VVRLIAAQLAEAGDKFDK..E..IKARVVNDLLQHFLNENLSREEITRHMSEAVEGLA..R....A....IP...SDMEQEKAMLVLAMVLTKKIANTMPSLLHRVFNTTVNYIGQQFHNYIARMMRE.........................
G7PH70_MACFA/45-234                    .................CEVSNGSGLRDECVTNLLVFGFLQ..S..CS..DN.SFRRELDALGRE..........................LP.V...P.A.A..Q.W...E...A.......Y-..............D.ELQTDGNRSSH......S.RMG...R.IE.......AD...SES..Q.........ED..VIRNIARHLAQVGDSMDR..S..IPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLL..Q....A....YP...TDMEKEKTMLVLALLLAKKVASHTPSLLRDVFQTTVNFINQNLRAYVRSLARN.........................
BID_CHICK/3-193                        .............qdiy---SNGS----DHMERMLLFAFLA..E..SS..GC.EFQEQLPSLQSQg.......................vlCS.V...K.D.A..L.C...Y...D.......SD..............G.ELQTDGNRSGH......L.QNG...E.LV.......PD...PEV..N.........EA..IVRTIAAQLAEIGDQLDK..Q..IKAKVVNDLVQHFLNENLPREEITRCLSQAVEGLA..R....A....IP...SDLEQEKAMLVLAMLLTKKVANQMPSLLQRVFSTTVNYISQHFHNYIVRMLRE.........................
A0A1U8CVY3_MESAU/1-71                  .................------------------------..-..--..--.------------..........................--.-...-.-.-..-.-...-...-.......--..............-.-----------......-.---...-.--.......--...---..-.........--..------------------..-..---------------------DRRNCLAKALDEVK..A....A....FP...RDMENEKAMLIMTLLLAKSVASHEPSLLRDVFQTTVNFINQNLLTYVRNLLRN.........................
W5NIN1_LEPOC/1-185                     .................--------------TSLVLFAFLQ..NqeCK..NK.ELQRELETLGEK..........................YL.E...D.C.Y..-.-...A...E.......ED..............G.ELQTDGHFCSD......V.REF...A.RE.......RQ...FDV..QgimpinaprDA..ELRNIAAGLIEIADQLEQ..R..VVARASESLVMKLRK--SSQQLWLNHLSSEVRQLM..Q....T....RLpglQHFSQERVLLALTMTLVKRVCEQAPSFLHGLFCTAVDYINSRQPNFMFNM---r........................
A0A091KR22_9GRUI/1-183                 .............ngsv------------QMECALLYTFLE..V..SP..DC.KFREQLHSLQSQg........................vVP.F...S.K.G..G.F...C...Y.......DD..............V.ELQTDGNRSGH......L.QNG...E.LV.......FD...HEV..N.........EE..IVRIIAAQLAEIGDQFDK..E..IKARVVNDLVQHFLNENLSGEEITRCLSEAVEGLA..R....A....IP...SDMEQEKAMLVLAMVLTKKIANTMPSLLQRVFSTTVNYISQQLHNYIVRMV--.........................
A0A2I3SGG1_PANTR/3-91                  .................CEVNNGSSLRDECITNLLVFGFLQ..S..CS..DN.SFRRELDALGHE..........................LP.V...L.A.P..Q.W...E...G.......Y-..............D.ELQTDGNRSSH......S.RLG...R.IE.......AG...ASD..N.........N-..------------------..-..-----------------------------------..-....-....--...-----------------------------------------------------tasaeeeteaa..............
A0A1D5P8E8_CHICK/4-193                 ..............diy---SNGS----DHMERMLLFAFLA..E..SS..GC.EFKEQLPSLQSQg.......................vlCS.V...K.D.A..L.C...Y...D.......SD..............G.ELQTDGNRSGH......L.QNG...E.LV.......PD...PEV..N.........EA..IVRTIAAQLAEIGDQLDK..Q..IKAKVVNDLVQHFLNENLPREEITRCLSQAVEGLA..R....A....IP...SDLEQEKAMLVLAMLLTKKVANQMPSLLQRVFSTTVNYISQHFHNYIVRMLRE.........................
A0A1U8CZB5_ALLSI/4-191                 .........gtysdgfs------------QLESLLLYSFLD..N..SQ..DC.AFKEKLQTLSCRht.....................pqcVP.H...R.T.A..F.H...S..fS.......DD..............G.ELQTDGNRSGH......F.QNG...E.--.......PG...SET..G.........E-..IYQIIGAQLAEIGDQLAA..E..MQAGPVDDLVQQFLNANLSSEEITRCLSQMVEQVL..K....S....IP...LDMDQEKAKLVLAMVLAKKVVNNVPSLLHRVFSTTVNYMNQYLHDYIHNIV--.........................
U3IN21_ANAPL/3-193                     .........qdihsggf-----------NQMERMLLFAFLE..E..SS..GC.EFKEQLPSLRSQg.......................ivYP.L...Q.D.I..L.Y...C...D.......SD..............G.ELQTDGNRSGH......F.QNG...E.QV.......FD...PEV..N.........EE..IVRTIAAQLAEIGDQLDK..E..VKAKVVNDLVQHFLNENLSREEITRCLSQAVEVLA..R....A....IP...SDLEREKAMLVLAMVLTKKVANKVPFLLQRVFSTTVNYISQHFHGYVARMLRE.........................
G3HQ86_CRIGR/3-191                     ................s-QVSNGSGLDTEHITNLLVFGFLQ..N..-S..KY.HFHRELEVLGQE..........................LP.V...P.V.Y..L.D...A...D.......E-..............D.ELQTDGSRASR......S.YHG...R.IQ.......PD...SES..Q.........ED..VIQRIAHHLAQVGDELNH..S..IQPTLVRQLAAQFMNVSLSEEDRRNCLAKALDEVK..T....A....FP...RDMENEKAMLIMTLLLAKSVASHEPSLLRDVFRTTVNFINQNLFTSVRNLLRN.........................
A0A091INR9_EGRGA/1-184                 ..............ngs-----------VQMESALLYTFLE..V..SS..DF.KFREQLYSLQSQg........................iVP.F...P.E.I..S.V...R...G.......CD..............DvELQTDGNRSGH......L.QNG...E.LV.......LD...PEV..N.........EE..VIRIIAAQLAEIGDQFDK..E..IKARVVNDLVQHFLNENLSREEITRCMSEAVEGLA..R....A....IP...LDMEKEKAMLVLAMVLTKKIANTMPSLLQHVFSTTVNYISQQLHNYIVRMV--.........................
A0A091ECP1_CORBR/1-179                 ..............ngs-----------LQMEHALLFTFLE..A..SS..DC.QFRDQLQSLQNQ..........................Q-.A...A.L.C..C.H...A...N.......DD..............D.ELQTDGNRSGH......F.QNG...E.LG.......L-...APT..N.........ED..VIRIIAAQLAEIGDQFDK..E..IQGRVVNNLVQHFLNENLSREEIILHMSSVVRELT..R....S....IP...SDMEQEKAMLVLAMVLTKKIVNTVPSLLHRVFNTTLNYMNQQLHNYIVEMV--.........................
H2QL73_PANTR/49-238                    .................CEVNNGSSLRDECITNLLVFGFLQ..S..CS..DN.SFRRELDALGHE..........................LP.V...L.A.P..Q.W...E...G.......Y-..............D.ELQTDGNRSSH......S.RLG...R.IE.......AD...SES..Q.........ED..IIRNIARHLAQVGDSMDR..S..IPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLL..Q....A....YP...RDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYVRSLARN.........................
A0A1S3WES5_ERIEU/11-228                ................s-QVSNGPGLWDTPVTNLLVFSFLQ..N..CC..DGdGFHQELETLRAElphpmflpgfqyeglrpagpklpqgaIG.V...L.P.Y..R.L...E...V.......SD..............D.ELQTDGSRFSL......G.PGV...E.EQ.......AD...SES..Q.........EE..AIQAIARRLADIGDSMDR..R..IPPALVERLAAQFRDGHLSEGERAARLAEALDQAM..H....A....GP...RELDVERLTLTLALLLARRVAAHAPSLLGTIFRTTVRFINQNLLAYVHNLVQ-d........................
A0A093RUG0_9PASS/54-207                .......tvhyrgwlvp------------------------..-..--..--.------------..........................--.-...-.R.S..Q.G...P...D.......DD..............S.ELQCDGNRSGH......L.ENG...E.LE.......AD...APT..N.........ED..VIRIIAAQLAEIGDKLDK..D..VQGNVVNDLVQHFLNENLSREEIMRHMSRVVRELA..Q....A....IP...ADMEQERVMLVLAMVLTKKIVNTVPSLLHRAFSVTVDFMNQQFHNYIDGMV--.........................
A0A2D0QTM1_ICTPU/3-197                 ..........dvhsfsq--------------TPLLFLTFLQ..Q..RP.lNS.ELKRELEKMHCDmklr.................aaptgIT.D...H.I.V..Y.T...Q...N.......HDldsn......iecdG.ELQTDGHSVQRivlhdvP.QVE...H.VL.......PV...PFD..E.........AN..AVREVAAELVRMADELNH..I..IVSQAAERLTKTLST--SPQKCLWSCLSQGVDTLL..K....D....VP...-GMHSERMVTALTFSLARAVCERAPRLLRDLCNTMMQY---------------tftnt....................
A0A093PP76_PHACA/2-182                 ...........gsvqpe---------------CVLLYAFLE..V..SS..DC.KFREQLHSLQSQ.........................gFA.L...K.G.S..Y.Y...Y...D.......DE..............V.ELQTDGNRSGH......F.QNG...E.PV.......FG...PEV..N.........EE..AVRIIAAQLTVIGDQFDR..E..IKAGVVNDLVQHFLNENLSGEEIIHRMSEAVEGLA..R....A....IP...SGMEQEKAMLVLAMVLTKKIVNTMPSLLQRVFSTTVNYISQQLHNYIIRMV--.........................
S9XDC5_CAMFR/168-354                   ...............sl--VSNGAGPQDERITSLLVFSFLQ..S..CS..PS.SFRRELEALGHQ..........................LS.M...C.T.A..-.-...-...-.......LD..............D.ELQTDGSQWSH......P.LGG...A.AD.......TV...SAS..Q.........EE..AIWDIARQLAQIGDTMGR..S..IHPGLIHGLAAQFTNGSLSEEDRRRGFATTLGQLL..Q....A....CP...ADVDQEKTLLVLTMLLAKEVASHTPALLQDVFRTTVNFINQNLLTYVRNLVQN.........................
A0A091WNX5_OPIHO/1-184                 ..............ngs-----------VQMERALLYTFLE..V..SS..DC.KFREQLHSLQSLg.......................tlSF.L...K.G.S..C.Y...Y...D.......DE..............V.ELQTDGNRSGH......M.QNG...E.LV.......FD...PEV..N.........EE..VIRIIAAQLAEIGDQFDK..E..IKARVVNDLVQHFLNENLSGEEITRRMSEAVEGLA..R....A....IP...SDMEREKAMLVLAMVLTKKIANTMPSLLQRVFSTTVSYISQQLHNYIVRMV--.........................
A0A2K5LVW2_CERAT/3-192                 .................CEVSNGSGLRDECVTNLLVFGFLQ..S..CS..DN.SFRRELDALGRE..........................LP.V...P.A.A..Q.W...E...A.......Y-..............D.ELQTDGNRSSH......S.RMG...R.IE.......AD...SES..Q.........ED..VIRNIARHLAQVGDSMDR..S..IPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLL..Q....A....YP...TDMEKEKTMLVLALLLAKKVASHTPSLLRDVFQTTVNFINQNLRAYVRSLARN.........................
A0A1S3FSZ5_DIPOR/3-194                 ................p-EVSNAAGFGRERITSLLVFGFLQ..S..SS..-D.KFRQELDTLGHE..........................LF.D...G.A.L..P.Q..pF...C.......AD..............D.ELQTDGLQVSR......S.-YG...R.IE.......AD...SES..Q.........DE..VIRSIARHLAQAGDEMEH..HlrIHPGLVSSLAAKFMDRSLSEEDRRSCLASALKEVG..Q....A....YP...KDMETEKATLIMAMLLARKVVTLTPSLCRDVFRTTVNFINQNLLIYVRNLVQN.........................
G1TB99_RABIT/12-207                    ................p-KVSSGPGPRDEHITNLLVLGFLQ..S..CC..SC.SFHEELQVLGRE..........................LL.S...E.A.E..L.A...D...S.......YDccs........yddD.ELQTDGNHASF......L.QMG...R.AE.......AG...SES..Q.........EE..VIRNIARRLAQIGDRMDH..H..IQPELLNNLVVEFVN-DHSEEDRRRRLASAVEQAM..E....T....WP...ADMEREKATLMLTMLLAKKLAEHTPSLLRAAFRAAVTLINQDLLAYVRNLAGN.........................
A0A2K5J9S2_COLAP/3-95                  .................CEVSNGSGLRDECITNLLVFGFLQ..S..CS..DN.SFHRELDALGRE..........................LP.V...P.A.P..Q.W...E...G.......Y-..............D.ELQTDGNRSSH......S.RMG...R.IE.......AE...VSD..N.........--..------------------..-..-----------------------------------..-....-....--...-----------------------------------------------------ntasveeeteaagsvv.........
F7DQE5_ORNAN/1-96                      .................------------------------..-..--..--.------------..........................--.-...-.-.-..-.-...-...-.......--..............-.-----------......-.---...-.--.......--...---..-.........--..---------------LDG..N..IQQGLVRDVARQFMNANLSEEDRRKYLAATMERVM..Q....A....VP...QELEREKATLLFALLLAKQVVNHSPTLLRSVFRTTVDYINRSLLAYTRNLARN.........................
A0A0D9RP74_CHLSB/45-234                .................CEVSNGSGLRDECITNLLVFGFLQ..S..CS..DN.SFRRELDALGRE..........................LP.V...L.A.T..Q.W...E...A.......Y-..............D.ELQTDGNRSSH......S.RMV...R.IE.......AD...SES..Q.........ED..VIRNIARHLAQVGDSMDR..S..IPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLL..Q....A....YP...TDMEKEKTMLVLALLLAKKVASHTPSLLRDVFQTTVNFINQNLRAYVRSLARN.........................
A0A0A0A4E6_CHAVO/1-184                 .............nesv------------QMESALLYTFLE..V..SS..DC.RFRDQLHSLQSQei......................lsF-.L...K.G.S..Y.C...C...D.......DE..............V.ELQTDGNRSGH......L.QNG...E.LV.......FD...PEV..N.........EE..VVRIIAAQLAEIGDQFDK..E..IQARVVNDLVQHFLNENLSGEEITRHMSEAVESLA..R....A....IP...SDMERERATLVLAMVLTKKIANTMPSLLQRVFRTTVNYINQQLHNYIVRMV--.........................
F7CU55_MONDO/68-258                    ............dfamd---------QDNRKTSLLLFNFLQ..C..SS..NS.FIQTELKELGQE..........................LN.R...P.P.H..F.Q...GgglE.......DN..............Y.ELQTDGNRSCH......F.EE-...E.EE.......SD...SES..Q.........EE..IIQRIAMQLAKIGDNIEN..S..IQPRVVDELVQWLRNVNLSTQEKKKYLAATMEKVMdmQ....T....IS...LDIGQEKATLLLTMLLAKKVMTHAPPLFRSVFQLTVDYINQNLRTYMRNLTRN.........................
H2P3K4_PONAB/1-96                      .................------------------------..-..--..--.------------..........................--.-...-.-.-..-.-...-...-.......--..............-.-----------......-.---...-.--.......--...---..-.........--..---------------MDR..S..IPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLL..Q....A....YP...TDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYVRSLARN.........................
G1KMF0_ANOCA/7-186                     ...........ndwpdt-------------STSVLLYSFLQ..H..SR..DC.TFVSDLNCLKNE..........................LL.V...S.R.I..S.D...D...D.......DD..............D.ELQTDGNRCGR......F.QAR...E.EV.......P-...---..D.........EE..IFRIIGAQLAEIGDKLTA..E..IETSVIQNLAQHFRRENMSKEVMTMQISHVVQELV..R....K....MP...LDMEKEKAMLVISMALAKKVVNSVPSLLQQVFNATVNYINQNLHDYVNNLA--pe.......................
A0A091N4S2_CARIC/1-184                 ..............ngs-----------VQMERALLYTFLE..V..SS..DC.KFREQLHSLQSQg.......................igSS.V...K.G.S..Y.C...Y...D.......DE..............V.ELQTDGNRSGY......M.QNG...E.LV.......FD...PEV..N.........EE..VVRIIAAQLAEIGDQFDK..E..IKARVVNDLVQHFLNENLSGEEITRRMSEAVEGLA..R....A....IP...SDMEQEKAMLVLAMVLTKKIANTMPSLLQRVFSTTVNYISQQLHNYIVRMV--.........................
F7ACD0_HORSE/1-187                     .................--VSNGSGLQDEHITHLLVFSFLQ..N..CS..KR.HFYKELEVLGHE..........................LP.V...Q.A.Y..L.W...E...D.......H-..............D.ELQTDGNRCSH......F.V-A...R.AE.......AD...SES..Q.........EE..IIQHIARQLAQIGDRMDD..S..IHPRLVNNLAMQFMNVNLSEEDRRQCLTSALEQVM..Q....T....YP...KDMEKEKTMLMLSMLLAKKVANHTPSLLRDVFRTTVNFINQNLLTYVRNLVRN.........................
A0A2I3GK37_NOMLE/3-84                  .................CEVNNGSGLSDECITNLLVFGFLQ..S..CS..DN.SFRRELDALGHE..........................LP.V...L.A.P..Q.W...E...G.......Y-..............D.ELQTDGNRSSH......S.RLE...R.IE.......AG...ASD..N.........--..------------------..-..-----------------------------------..-....-....--...-----------------------------------------------------ntasa....................
Q17QH5_BOVIN/3-190                     ................l-KVSNGPGPGDERTTSLLLLGFLQ..S..CP..HS.CFQRELEALGHE..........................LP.G...H.L.F..-.-...-...-.......HD..............D.ELQTDGNRCSH.....fP.LAA...E.AE.......TD...SER..Q.........EE..AVREVARQLAQIGDRLEG..S..IHPGMVAGLASRFSVRSLSEEDRRQCLAAALEQLM..Q....T....CP...PDVDHEKTQLLLTMLLAKKIADHSPALLRDVFHTTVTFINQNLLAYVRNLVRN.........................
A0A091UUF5_PHORB/1-184                 .............ngsv------------QMECALLYTFLE..V..SS..DC.KFREQLPSLQSQgi......................vpF-.L...K.G.S..S.C...Y...D.......DE..............V.ELQTDGNRSGH......L.QNG...G.LV.......FD...PEV..N.........EE..VVRIIAAQLAEIGDQFDK..E..IKARVVNDLVQHFLNENLSGEEITRRMSEAVEGLA..R....A....IP...SDMEQEKAMLVLAMVLTKKIANTMPSLLRRVFSTTVNYISQQLHNYIVRMV--.........................
A0A091GP84_BUCRH/1-180                 ...........ngsvqk--------------ECVLLYTFLE..V..SP..DC.KFREQLCSLRSQg........................iVA.F...P.A.G..ScY...D...D.......DE..............M.ELQTDGNRSGH......L.QNG...E.PV.......LD...P--..-.........-E..VVRIIASRLAAIGDQFDK..E..IHARVVNDLVQQFLNENLSREEITRCLSEAVEGLV..Q....A....IP...LDMEQEKAKLVLAMVLTKKIANTMPSLLHRVFSTTVNFISQQLPNYIVRLV--.........................
BID_HUMAN/3-192                        .................CEVNNGSSLRDECITNLLVFGFLQ..S..CS..DN.SFRRELDALGHE..........................LP.V...L.A.P..Q.W...E...G.......Y-..............D.ELQTDGNRSSH......S.RLG...R.IE.......AD...SES..Q.........ED..IIRNIARHLAQVGDSMDR..S..IPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLL..Q....A....YP...RDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYVRSLARN.........................
#=GR BID_HUMAN/3-192             SS    .................SSXXXSXXXXXTHHHHHHHHHHHH..H..TS..XS.SSHHHHHHHGGG..........................XX.X...X.X.S..X.S...S...X.......S-..............X.SSXXX-S-S--......-.TTT...-.ST.......TS...-HC..H.........HH..HHHHHHHHHHHHHHHHHH..C..SSTTSHHHHHHHHHCHCCCCCCCCHHHHHHHHHHH..C....T....S-...-SSHCHHHHHHHHHHHHHHHHHH-TTTHHHHHHHHHHHHHCCCHHHHHHHCCT.........................
F7DQF1_ORNAN/9-135                     .........vllprspr------------------------..-..--..--.------------..........................--.-...-.-.-..-.-...-...-.......--..............-.-----------......-.---...-.--.......PE...SGH..E.........EE..AIRLIAEQLAQIGDELDG..N..IQQGLVRDVARQFMNANLSEEDRRKYLAATMERVM..Q....A....VP...QELEREKATLLFALLLAKQVVNHSPTLLRSVFRTTVDYINRSLLAYTRNLARN.........................
A0A094L7K7_ANTCR/1-184                 ..............ngs-----------VQMESALLYTFLD..V..SS..DC.QFREQLQSLQSQg.......................lvSS.L...K.G.T..Y.C...Y...E.......DE..............L.ELQTDGNRSGH......L.QNG...E.PV.......FD...HEV..N.........EE..VIRNIAAQLAEVGDQFDK..E..IRAREVNDLVQHFLNENLSSEEMTRRMSKAVEALA..R....A....IP...SDMEQEKAMLVLAMVLTKRIANTMPSLLQRVFSTTVNYISQQLHNYIIRMV--.........................
F7IH59_CALJA/46-232                    .................CEVSNGSDLQDERITNLLVFGFLQ..S..CS..NH.SFHRELEALGHE..........................LP.-...-.-.-..Q.W...E...E.......PD..............E.ELQTDGNRSSH......S.HVG...R.IE.......AD...SES..Q.........ED..VIRSIARHLAHIGDSMDR..S..IPLDLVDRLALQLRNACRSEEDRRRDLASALEQLL..Q....A....HP...TDMDKEKTMLVLALLLAKKVADHTPSLLRDVFRTTVNFINQNLRAYVRSLTRN.........................
F7DU73_XENTR/4-185                     svekillsyleidlpst------------------------..-..--..NE.ELREELSLFAGGk.......................prLQ.G...R.A.L..-.-...F...Q.......LE..............G.ELETDGNVQLRd....sG.TIA...Y.EG.......VE...QEV..D.........EE..LCRRIAAQLAEMGDKLERemK..IKPEVVNGLVDAMLNQTLLEE----HLAATVQSLV..Q....T....VP...PGVEQEVAAVAIAMILTKKAVTNVPSLLQNICRTTTRFVERNYRACLERLAR-q........................
A0A1D5QH89_MACMU/3-192                 .................CEVSNGSGLRDECVTNLLVFGFLQ..S..CS..DN.SFRRELDALGRE..........................LP.V...P.A.A..Q.W...E...A.......Y-..............D.ELQTDGNRSSH......S.RMG...R.IE.......AD...SES..Q.........ED..VIRNIARHLAQVGDSMDR..S..IPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLL..Q....A....YP...TDMEKEKTMLVLALLLAKKVASHTPSLLRDVFQTTVNFINQNLRAYVRSLARN.........................
A0A287BP00_PIG/1-186                   .................-QVSNGSSLQDERITNLLVFGFLQ..S..CP..HA.SFHKELEVLGHE..........................LP.V...H.T.S..G.-...-...-.......-S..............D.ELQTDGNRCSY......F.MED...A.AE.......TD...SES..Q.........EA..VIRDIARHLARIGDRMEY..G..IRPGLVDSLAAQFRNQSLSEEDRRQGLAAVLQQLV..H....S....YP...ADMGQEKTLLVLTMLLARKVAEHSPALLRDVFHTTVNFINQNLLTYLRNLVQ-s........................
A0A2I0MKV4_COLLI/2-191                 ............eqvng------S----VQMESVLLYSFLE..V..SP..DC.MFREQLHSLQSQe........................iVP.V..lQ.G.K..Y.W...Y...D.......DE..............M.ELQTDGNRSGH.....lL.QNG...E.PV.......FE...PQV..D.........EE..VVRLIAVQLAEIGDQFDK..E..IKTRLVNDLVQQFLNENLPGEAITRRMSEAVEGLV..R....A....MP...PDMEQEKATLVLAMVLTKKIVNTVPSLLPRVFRTTVNYINQHLHNYIVRMLR-g........................
G1MGI0_AILME/3-192                     ................a-QVSNGPGLQDEHITNLLVFGFLQ..N..CS..NS.NFHKELEVLGHE..........................VS.M...P.A.Y..L.Q...E...D.......YD..............D.GLQTDGNRCSY......F.L-E...S.GE.......RD...SQG..Q.........EE..IIQDIARQLAQIGDDMDH..S..IHPGLMNNLAMQFMNVNLSEEDRRKSLTAALEQVM..Q....T....YP...MDMEEEKTMLILAMLLAKKVADHTPSLLRDVFRTTVNFINQNLFTYVRNLVRN.........................
I3N331_ICTTR/3-192                     ................s-EVSNGSDLRNEYITNLLVLDFLQ..S..FS..DC.KFHQELRTLGQE..........................LP.V...R.T.Y..L.E...G...E.......RE..............D.ELQTDGNRAS-......L.FMG...R.IE.......AD...SES..Q.........EE..VIQNIARHLAQVGDEMDR..S..IQPELVNELVARFMNAGLSEEDRSNCLDTTLKAAM..Q....T....YP...KDMENEKTMLIMTMLLAKKVANHTPSLLHDVFRATVNFINQNLFTYVRDLVRN.........................
A0A1S3KQ61_SALSA/2-196                 ............dcgnv------------QCTPLVFLTFLQqqS..CS..SA.ELRIQLDSLAQE..........................LK.R...T.Q.D..I.N...G...NglglnihEE..............G.ELQTDGHFCSSs....rI.LLE...G.LEpqaalawPD...NPA..D.........EE..ALRGVAAGLIEIADQLER..S..VMAQAAENLTKKLQK--YSIGRWKHHLALEVEWVK..K....QglgpVL...DYLPQEKVIMALTLTLVKGVCERAPLLLRNLFSAAVQFINP------------tva......................
A0A287AYM3_PIG/3-189                   ................s-KVSNGSSLQDERITNLLVFGFLQ..S..CP..HA.SFHKELEVLGHE..........................LP.V...H.T.S..G.-...-...-.......-S..............D.ELQTDGNRCSY......F.MED...A.AE.......TD...SES..Q.........EA..VIRDIARHLARIGDRMEY..G..IRPGLVDSLAAQFRNQSLSEEDRRQGLAAVLQQLV..H....S....YP...ADMGQEKTLLVLTMLLARKVAEHSPALLRDVFHTTVNFINQNLLTYLRNLVQ-s........................
A0A087R1G3_APTFO/1-183                 ..............ngs-----------VRMEHVLLYTFLE..V..SS..DC.NFREQLHSLQSQgi......................vpF-.L...K.G.S..Y.C...Y...D.......DE..............V.ELQTDGNRSGH......L.QNG...E.LV.......HD...PEI..N.........E-..ILRIVATQLAEIGDQLDK..E..IKPRTVNDLVQHFLNENLSGEEITRYMSEAVEGLA..R....A....LP...SDMEQEKAMLVLAMVLTKKIANTMPSLLQRVFSTTVNYISQQFHNYIVRMV--.........................
A0A093CDL5_TAUER/1-183                 .............ngsv------------QMECTLLYNFLD..V..SS..DC.RFKEQLHSLQNE..........................GP.V...S.F.LkgS.C...Y...D.......DE..............V.ELQTDGNRSGH......L.QNG...D.VV.......FD...PEV..N.........EE..VVRIIAAQLAEIGDQFDK..E..IKARVVNDLVQHFLNENLSGEEITRRMAEAVEGLA..R....A....IP...SDMEREKAMLVLAMVLTKKIVNTMPSLLRRVFSTTVNYISQQLHNCIVRMV--.........................
Q56VD1_XENLA/4-183                     .nvktilvsyleidikn------------------------..-..-H..KD.EFWEELSWFARE..........................EG.K...L.V.A..Q.M...G...R.......ND..............G.DLETDGNVQFR.....sT.GTI...V.YE.......GE...AEV..D.........EE..LCRRIATQLAEMGDKLER..EmrIKPEVVNGIVDALLNHTLNEE----YLAATVQSLV..Q....T....AP...PGVEQELMSVAIALILTKKAVTNVPSLLHNICCTTTHFIERNYRACLERLAR-q........................
L5MJN0_MYODS/57-247                    ................p-KGSNGSGLQDERITDLLVFGFLQ..N..CS..NY.NFHKELQVLGHD..........................LS.V...P.A.C..L.W...E...N.......HD..............D.ELQTDGNQYSH......F.VLE...S.RE.......TD...SES..Q.........DE..IIQNIARQLAHIGDRMDR..S..IPPRLVNHLAIQFMNGNLSEEERRECLAAALEQVM..H....T....YP...KDMEKEKTMLMLTMLLAKKVADHTPSLLHDVFRTTVNVINQNLLTYVRNLVRN.........................
F6WQU1_MACMU/32-221                    .................CEVSNGSGLRDECVTNLLVFGFLQ..S..CS..DN.SFRRELDALGRE..........................LP.V...P.A.A..Q.W...E...A.......Y-..............D.ELQTDGNRSSH......S.RMG...R.IE.......AD...SES..Q.........ED..VIRNIARHLAQVGDSMDR..S..IPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLL..Q....A....YP...TDMEKEKTMLVLALLLAKKVASHTPSLLRDVFQTTVNFINQNLRAYVRSLARN.........................
A0A093IUQ8_FULGA/1-116                 .................------------------------..-..--..--.------------..........................--.-...-.-.-..-.-...-...-.......--..............-.-----------......-.---...-.--.......-D...PEV..N.........EE..VVRIIAAQLAEIGDQFDK..E..IKARVVNDLVQHFLNENLSGEEITRHMSEAVEGLA..R....A....IP...SDMEQEKAMLVLAMVLTKKIANTMPSLLQRVFSTTVNYISQQLHNYIVRMV--.........................
M7ARC5_CHEMY/27-215                    .........tavrglrg----------DVQVERILVYSFLQ..N..CH..NC.DFREELDSLRSQ..........................VM.VsppK.N.F..L.S...D...E.......FD.............dG.ELQTDGNRSGR......F.SNG...-.-E.......PD...SVV..D.........ED..IFRLIGAQLAEIGDQVAR..E..IQPRVVNDLVQQFVNENLSKEEIMRRLSNTVEGLV..R....T....IP...LEMEQEKAMLVLAMVLARTVANKMPSLLHRVFNTTVNYVNQNLHNYVVNL---g........................
A0A2K5J9S8_COLAP/63-252                .................CEVSNGSGLRDECITNLLVFGFLQ..S..CS..DN.SFHRELDALGRE..........................LP.V...P.A.P..Q.W...E...G.......Y-..............D.ELQTDGNRSSH......S.RMG...R.IE.......AD...SES..Q.........ED..VIRNIARHLAQVGDSMDR..S..IPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLL..Q....A....SP...TDMEKEKAMLVLALLLAKKVASHTPSLLRDVFQTTVNFINQNLRAYVRSLARN.........................
A0A140T8G9_CHICK/3-193                 .............qdiy---SNGS----DHMERMLLFAFLA..E..SS..GC.EFKEQLPSLQSQg.......................vlCS.V...K.D.A..L.C...Y...D.......SD..............G.ELQTDGNRSGH......L.QNG...E.LV.......PD...PEV..N.........EA..IVRTIAAQLAEIGDQLDK..Q..IKAKVVNDLVQHFLNENLPREEITRCLSQAVEGLA..R....A....IP...SDLEQEKAMLVLAMLLTKKVANQMPSLLQRVFSTTVNYISQHFHNYIVRMLRE.........................
U3K4T9_FICAL/2-184                     ............eqing------S----LQMEHALLFTFLD..A..SS..DC.QFKDQLHSLHSP..........................Q-.-...I.M.S..C.Q...A...S.......DD..............D.ELQTDGNRSGH......F.QNG...E.LE.......L-...PPT..N.........EE..VIRIIAAQLAEIGDQFDK..E..IQARVVRDLVQHFVNERLSREEITLHLSRAVNKLL..T....S....IP...SDMAQEKAMLVLAMVLTKKIVNTMPSLLRRVYDATVNYMNQQFHDYIVEMLG-e........................
G3T1D2_LOXAF/1-192                     .................--VSNGSGLQNERITNLLVFSFLK..N..CP..SC.HFHEELAELSYE..........................LP.L...P.A.H..L.R...E...E.......Y-..............D.ELQTDGNRNSHfh..fqS.FQG...R.LE.......QD...SGS..Q.........EE..VIQSIAERLAQIGDEMES..Q..VHPSLVQNLARQFMDRNLSEEDRRKHLATAVDRVM..Q....T....CL...LDMELEKKKLMLTMLLAKKVADHMPSLLRDVFRTTVNFINQNLLTYVRNLARN.........................
A0A091VX00_NIPNI/1-184                 ..............ngs-----------VQMESVLLYTFLE..V..SS..DC.KFREQLHSLQGRg.......................ivPF.V...K.G.S..Y.C...Y...D.......DE..............V.ELQTDGNRSGH......L.QNG...E.LV.......LA...PEV..N.........EE..VVRIIAAQLAEIGDQFDK..E..IQARVVNDLVQHFLNENLSGEDITRLLSEAVEGLA..Q....A....IP...SDMEQEKAILVLAMVLTKKIANTMPSLLQRVFSTTVNYISQQLHNYIVRMV--.........................
A0A226PLU2_COLVI/5-193                 ...........icsdgc-----------GHVEHMLLFAFLV..E..SS..GC.EFREQLPFLQSQg.......................ilCS.L...K.E.A..H.S...Y...D.......SD..............G.ELQTDGNRSGH......L.QNG...E.LV.......LD...PEV..N.........EE..IIRTIAAQLAEIGDQLDK..Q..IKAKVVNDLVQHFLNENLPREEITRCLSQAVEGLA..R....A....IP...SDLEQEKAMLVLAMLLTKKVANRVPSLLQRVFSTTVNYISQHLHNYIVQMLRE.........................
BID_PIG/3-189                          ................s-KVSNGSSLQDERITNLLVFGFLQ..S..CP..HA.SFHKELEVLGHE..........................LP.V...H.T.S..G.-...-...-.......-S..............D.ELQTDGNRCSY......F.MED...A.AE.......TD...SES..Q.........EA..VIRDIARHLARIGDRMEY..G..IRPGLVDSLAAQFRNQSLSEEDRRQGLAAVLQQLV..H....S....YP...ADMGQEKTLLVLTMLLARKVAEHSPALLRDVFHTTVNFINQNLLTYLRNLVQ-s........................
#=GR BID_PIG/3-189               SS    ................X-XXXXXXXXXXXXXXXXXXXXXXX..X..XX..XX.XXXXXXXXXXXX..........................XX.X...X.X.X..X.-...-...-.......-X..............X.XXXXXXXXXXX......X.XXX...X.XX.......XX...XX-..H.........HH..HHHHHHHHHHHHHHHHHS..-..---S-----XXXXXXXXXXXXXXXXXXXXXXXXXX..X....X....XX...XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X........................
M3WEH6_FELCA/3-193                     ................s-QVSNGSSLQDERITNLLVFGFLQ..N..CS..NY.NFHKELEVLGRE..........................LP.V...PpA.Y..L.Q...E...D.......HD..............D.GLQTDGNRCSR......F.L-D...S.EE.......TD...SES..Q.........EE..IIQDIARQLAQIGDRMDH..S..IHPRVVNNLAMQFMNVNLSEEDRRKHLAAALEQVL..Q....T....YP...KDMEREKTVLMLAMVLAKKVADHTPSLLRDVFRTTVNFINQNLLTYVRNLVRN.........................
F7IEQ7_CALJA/1-96                      .................------------------------..-..--..--.------------..........................--.-...-.-.-..-.-...-...-.......--..............-.-----------......-.---...-.--.......--...---..-.........--..---------------MDR..S..IPLDLVDRLALQLRNACRSEEDRRRDLASALEQLL..Q....A....HP...TDMDKEKTMLVLALLLAKKVADHTPSLLRDVFRTTVNFINQNLRAYVRSLTRN.........................
A0A2K5LVY0_CERAT/3-104                 .................CEVSNGSGLRDECVTNLLVFGFLQ..S..CS..DN.SFRRELDALGRE..........................LP.V...P.A.A..Q.W...E...A.......Y-..............D.ELQTDGNRSSH......S.RMG...R.IE.......AG...ASD..N.........N-..------------------..-..-----------------------------------..-....-....--...-----------------------------------------------------tasveeeteaagsvvvelgrhgaa.
A0A087VAW2_BALRE/1-182                 ..............ngs-----------VRMERALLYTFLE..V..SS..DC.KFREQLQSLQSQg........................gVF.F...P.R.Y..-.C...Y...D.......DE..............V.ELQTDGNRSGH......L.QNG...E.LV.......FD...PEV..N.........EE..VVRIIAAQLAEIGDQFDK..E..IKARVVNDLVQHFLNENLSGEEITRRMSEAVEGLA..R....A....IP...SDMEQEKAMLVLAMVLTKKIANTMPSLLQRVFSTTVNYISQQLHNYIVRMV--.........................
G5BWN8_HETGA/3-193                     ................a-KVGNGAGFRDESITNLLVYSFLH..T..RN..NS.NFHPELEALGQE..........................LP.V...G.V.C..L.E...A...D.......HD..............D.ELQTDGNRGSR.....lL.YGG...R.RE.......GD...SEN..Q.........E-..IIHSIAWHLAEIGDELDR..S..IQPGLVNQLAMHFRNPGLSEEGRRHYLAATVEEVM..Q....T....YA...TDMEQEKAKLITAMLLVRKVADHTPSLLRDIFHTTVNFINQNLLTYMRDLIRN.........................
Q05KI6_BOVIN/3-190                     ................l-KVSNGPGPGDERTTSLLLLGFLQ..S..CP..HS.CFQRELEALGHE..........................LP.G...H.L.F..-.-...-...-.......HD..............D.ELQTDGNRCSH.....fP.LAA...E.AE.......TD...SER..Q.........EE..AVREVARQLAQIGDRLEG..S..IHPGMVAGLASRFSVRSLSEEDRRQCLAAALEQLM..Q....T....CP...PDVDHEKTQLLLTMLLAKKIADHSPALLRDVFHTTVTFINQNLLAYVRNLVRN.........................
A0A2K5J9S4_COLAP/3-192                 .................CEVSNGSGLRDECITNLLVFGFLQ..S..CS..DN.SFHRELDALGRE..........................LP.V...P.A.P..Q.W...E...G.......Y-..............D.ELQTDGNRSSH......S.RMG...R.IE.......AD...SES..Q.........ED..VIRNIARHLAQVGDSMDR..S..IPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLL..Q....A....SP...TDMEKEKAMLVLALLLAKKVASHTPSLLRDVFQTTVNFINQNLRAYVRSLARN.........................
A0A2K5LVW4_CERAT/52-241                .................CEVSNGSGLRDECVTNLLVFGFLQ..S..CS..DN.SFRRELDALGRE..........................LP.V...P.A.A..Q.W...E...A.......Y-..............D.ELQTDGNRSSH......S.RMG...R.IE.......AD...SES..Q.........ED..VIRNIARHLAQVGDSMDR..S..IPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLL..Q....A....YP...TDMEKEKTMLVLALLLAKKVASHTPSLLRDVFQTTVNFINQNLRAYVRSLARN.........................
F7H9R6_MACMU/1-93                      .................------------------------..-..--..--.------------..........................--.-...-.-.-..-.-...-...-.......--..............-.-----------......-.---...-.--.......--...---..-.........--..---------------MDR..S..IPPGLVNGLALQLRNT---SCDRNRDLATALEQLL..Q....A....YP...TDMEKEKTMLVLALLLAKKVASHTPSLLRDVFQTTVNFINQNLRAYVRSLARN.........................
A0A226N1M7_CALSU/23-212                ..........dicsdgc-----------GHVEHMLLFAFLV..E..SS..GC.EFREQLPFLQSQg.......................vlCS.L...K.E.A..H.S...Y...D.......SD..............G.ELQTDGNRSGH......L.QNG...E.LV.......LD...PEV..N.........EE..IIRTIAAQLAEIGDQLDK..Q..IKAKVVNDLVQQFLNENLPREEITRCLSQAVEGLA..R....A....IP...SDLEQEKAMLVLAMLLTKKVANRVPSLLQRVFSTTVNYISQHLHNYIVQMLRE.........................
F1Q0Y3_CANLF/12-203                    ................s-KVSNGSGPQDERITNLLVFGFLQ..N..CS..NY.NFHEELELLGRE..........................LP.V...P.A.Y..L.K...E...D.......YD..............D.ELQTDGNRCSY.....fL.DGG...A.RG.......LD...SES..Q.........EE..IIQDIARQLAQIGDRMDH..S..IHPGLVNNLAMQFMNVNLSEEDRRKHLAAALEQAM..Q....T....YP...KDMEKEKTMLMLAMLLAKKVADHTPSLLRDVFHTTVNFISQNLLTYVRNLVRN.........................
H0ZQI0_TAEGU/1-140                     .................------------------------..-..--..--.------------..........................--.-...-.-.-..-.-...-...-.......-D..............D.ELQTDGNRSGH......F.QNA...VlRE.......WL...AQT..N.........EE..VIRIIAAQLAEIGDQFDR..E..IQERVVNGLAQHFLNENLSYEEIIQHMNRAVRELT..R....A....IP...ADMEQEKAMLVLAMVLTRRIVNSVPSLLRRVITTTLNYMNQQFHNYILEMV--sa.......................
L5JTG3_PTEAL/77-267                    ................p-KISNGARLQHEHITDLLVFGFLQ..N..CC..NS.NFHKELKALGHD..........................LP.V...P.A.Y..P.R...E...D.......YD..............D.ELQTDGNRCSH......I.VLE...R.EE.......TE...SEN..Q.........EE..IIQNIARQLAQIGDRMDS..R..IPPRVVNYLAMEFMNVDLSEEDRKDCLSAALEEVM..K....T....YP...KDMEREKTMLMLTMLLAKKVADHTPSLLRGVFHTTVNFINQNLLTYVRNLLRN.........................
A0A093PAB0_PYGAD/1-183                 ..............ngs-----------VRMEHVLLYTFLE..V..SS..DC.NFREQLHSLQSQgi......................vpF-.L...K.G.S..Y.C...Y...D.......DE..............V.ELQTDGNRSGH......L.QNG...E.LV.......HD...PEV..N.........E-..ILRIIATQLAEIGDQLDK..E..IKPRAVNDLVQHFLNENLSGEEITRYMSEAVEGLA..R....A....LP...SDMEQEKAMLVLAMVLTKKIANTMPSLLQRVFSTTVNYISQQLHNYIVRMV--.........................
A0A091U308_9AVES/1-118                 ................v------------------------..-..--..--.------------..........................--.-...-.-.-..-.-...-...-.......--..............-.-----------......-.---...-.--.......PD...PEL..N.........EE..IIRVIALQLAEIGDQLDK..E..IKARVVNDLVRHFLNENLSGEEITRHMSEAVEGLA..R....A....IP...SGMEQEKAMLVLAMVLTKKIVNTMPSLLQRVFSTTVNYISQQLHNYIVRMV--.........................
A0A093GWD1_DRYPU/1-184                 ..............ngs-----------VQMEHVLLYTFLE..A..SP..DC.KFREQLQCLQSQg.......................mvSA.L...R.G.S..C.Y...E...D.......EE..............V.ELQTDGNRSGH......M.QNG...E.AV.......LD...HEV..N.........EE..VIRLIAAQLAAIGDRFDR..E..IKARVVNDLVQHFLNENLSAEEITQLMSEAVEGLV..Q....A....MP...SDLEREKVMLVLAMLLTKKIANTMPSLLQRAFSATVNYINQQLHNYIARLV--.........................
A0A091S1P2_NESNO/1-181                 .............ngsv------------QMECALLYTFLE..V..SP..DC.KFREQLHSLQNK..........................QF.Q...W.Q.Y..C.C...C...Y.......DD..............A.ELQTDGNRSGH......M.QNG...E.PV.......SD...PQV..H.........DE..VVRIIAAQLAEIGDQFDK..E..IKARVVNDLVQHFLNENLSREEITRHMSEAVEELA..R....A....IP...SDMEREKAVLVLAMVLTKKIANTMPFLLPRVFSTTVNYISQQLHNYVARMV--.........................
H0WLJ8_OTOGA/1-198                     .................CDVSNGSGLRDEHLTGLLVYGFLQ..S..CS..NS.GFQRELEELGHEpfv....................rthLL.V...R.T.H..L.H...E...E.......LD.............eD.ELQTDGSRASR......F.YAE...R.IE.......AD...SGS..Q.........ED..VIQNFARRLAQIGDSMDR..S..IPPRLVNNLVQQFRNPSLSEENRRGHLAAALEQVM..Q....T....CP...ADLTEEKATLLLIMLLAKKVADHTPSLLPVVFRTTVNFINRNLLASVRNLARN.........................
A0A091HJX1_CALAN/1-115                 .................------------------------..-..--..--.------------..........................--.-...-.-.-..-.-...-...-.......--..............-.-----------......-.---...-.--.......-D...PEV..N.........EE..VIRIIAAQLAEIGDQFDK..E..IKARVVNDLVQHFLNENLSAEEITRRMSEAVEEIV..R....A....IP...SDMEKEKAMLVIAMVLTKKIANTMPSLLQHVFSTTVNYISQ-LHNYIVRMV--.........................
A0A091PDZ4_LEPDC/1-183                 ..............ngs-----------VQMEHMLLYTFLE..V..SS..DC.RFREQLPSLQSLg........................tVP.V...A.N.V..C.L...Y...D.......DD..............V.ELQTDGNRSGH......L.QNG...E.LV.......FD...PAV..N.........EE..VVRIIAAQLAEIGDQFDK..E..IKARVVNDLVQHFLNENLSGEEITRHMSAAVEGLA..R....A....IP...SDVEQEKAMLVLAMLLTKKIANTMPSLLHRVFSATVNYISQQLHNYIVRMV--.........................
A0A096NVY7_PAPAN/52-241                .................CEVSNGSGLRDECVTNLLVFGFLQ..S..CS..DN.SFRRELDALGRE..........................LP.V...P.A.A..Q.W...E...A.......Y-..............D.ELQTDGNRSSH......S.RMG...R.IE.......AD...SES..Q.........ED..VIRNIARHLAQVGDSMDR..S..IPPGLVNGLALQLGNTSRSEEDRNRDLATALEQLL..Q....A....YP...TDMEKEKTMLVLALLLAKKVASHTPSLLRDVFQTTVNFINQNLRAYVRSLARN.........................
A0A2I3GZZ6_NOMLE/22-211                .................CEVNNGSGLSDECITNLLVFGFLQ..S..CS..DN.SFRRELDALGHE..........................LP.V...L.A.P..Q.W...E...G.......Y-..............D.ELQTDGNRSSH......S.RLE...R.IE.......AD...SES..Q.........ED..IIRNIARHLAQVGDSMDR..S..IPPGLVNGLALQLRNTSRSEEDRNRDLATALEQLL..Q....A....YP...RDMEKEKTMLVLALLLAKKVASHTPSLLRDVFHTTVNFINQNLRTYVRSLARN.........................
A0A094NRU2_9AVES/1-184                 .............ngsv------------QMECALLYSFLE..V..SS..DC.KFREQLHCLQSQgi......................vpF-.L...K.G.G..Y.C...Y...D.......DE..............V.ELQTDGNRSGH......M.QNG...E.LV.......FD...PEI..N.........EE..IVRIIAAQLAEIGDQFDK..E..IKARVVNDLVQHFLNENLSGEEITQRMSEAVEGLA..R....A....IP...SDMEQEKATLVLAMVLTKKIANTMPSLLHRVFSTTVNYISQQLHNYIAAMV--.........................
G3UR49_MELGA/3-196                     ..............ssh---SRGKSDGSDHMERMLLFAFLA..E..SS..GC.EFREQLPFLQSRg.......................llCA.V...K.G.V..Q.S...Y...D.......SD..............G.ELQTDGNRSGH......L.QNG...E.LV.......LD...PEV..N.........EE..IVRTIAAQLAEIGDQLDK..Q..IKAKVVNDLVQHFLNENLPREEITRCLSQAVEGLA..R....A....VP...SDLEQEKAMLVLAMLLTKKVANQVPSLLQRVFSTTVNYISQHLHNYIVRMLRE.........................
D3Z463_MOUSE/3-52                      ................s-EVSNGSGLGAEHITDLLVFGFLQ..S..S-..-G.CTRQELEVLGRE..........................LP.V...Q.A.Y..W.E...A...D.......--..............-.-----------......-.---...-.--.......--...---..-.........--..------------------..-..-----------------------------------..-....-....--...-----------------------------------------------------l........................
BID_MOUSE/3-192                        ................s-EVSNGSGLGAEHITDLLVFGFLQ..S..S-..-G.CTRQELEVLGRE..........................LP.V...Q.A.Y..W.E...A...D.......LE..............D.ELQTDGSQASR.....sF.NQG...R.IE.......PD...SES..Q.........EE..IIHNIARHLAQIGDEMDH..N..IQPTLVRQLAAQFMNGSLSEEDKRNCLAKALDEVK..T....A....FP...RDMENDKAMLIMTMLLAKKVASHAPSLLRDVFHTTVNFINQNLFSYVRNLVRN.........................
#=GR BID_MOUSE/3-192             SS    ................X-XXXXXXXXXXXHHHHHHHHHHHH..H..S-..-S.SXHHHHHHHHXX..........................XX.S...S.X.X..X.X...X...X.......XX..............X.XXXXXXXXXXX.....SX.XXX...X.XX.......XX...XX-..H.........HH..CHHHHHHHHHHHHHHHHH..G..-XSSSHHHHHHHHXXSSSSSSSTTHHHHHHHHHHH..H....H....SX...STHHHHHHHHHHHHHHHHHHHHHXTTXHHHHHHHHHHHHHHTTSXHHHHHHHH.........................
BID_RAT/3-193                          ................s-EVSNGSGLGAEHITNLLVFGFLR..N..-N..DR.DFHQELEVLGQE..........................LP.V...Q.V.Y..L.E...G...D.......RE..............D.ELQTDGSRASR.....sF.YHG...R.IE.......PD...SES..Q.........DE..VIHNIARHLAQAGDELDH..S..IQPTLVRQLAAQFMNGSLSEEDKRNCLAKALDEVK..T....S....FP...RDMENDKAMLIMTMLLAKKVASHAPSLLRDVFRTTVNFINQNLFSYVRDLVRN.........................
L7N431_XENTR/5-185                     .vekillsyleidlprt------------------------..-..--..NE.ELREELSLFAGGk.......................prLQ.G...R.A.L..F.-...-...Q.......SE..............G.ELETDGNVQLRd....sG.TIA...Y.EG.......VE...QEV..D.........EE..LCRRIAAQLAEMGDKLERemK..IKPEVVNGLVDAMLNQTLLEE----HLAATVQSLV..Q....T....VP...PGVEQEMAAVAIAMILTKKAVTNAPSLLQNICRTTTRFVERNYRACLERLAR-q........................
A0A2D0QVL4_ICTPU/11-208                .......smmdvhsfsq--------------TPLLFLTFLQ..Q..RP.lNS.ELKRELEKMHCDmklr.................aaptgIT.D...H.I.V..Y.T...Q...N.......HDldsn......iecdG.ELQTDGHSVQRivlhdvP.QVE...H.VL.......PV...PFD..E.........AN..AVREVAAELVRMADELNH..I..IVSQAAERLTKTLST--SPQKCLWSCLSQGVDTLL..K....D....VP...-GMHSERMVTALTFSLARAVCERAPRLLRDLCNTMMQY---------------tftnt....................
A0A1L8GQT1_XENLA/4-183                 .nvktilvsyleidikn------------------------..-..-H..KD.EFWEELSWFARE..........................EG.K...L.V.A..Q.M...G...R.......ND..............G.DLETDGNVQFR.....sT.GTI...V.YE.......GE...AEV..D.........EE..LCRRIATQLAEMGDKLER..EmrIKPEVVNGIVDALLNHTLNEE----YLAATVQSLV..Q....T....AP...PGVEQELMSVAIALILTKKAVTNVPSLLHNICCTTTHFIERNYRACLERLAR-q........................
#=GC SS_cons                           ................XSSXXXSXXXXXTHHHHHHHHHHHH..H..TS..-S.SSHHHHHHHHGG..........................XX.S...S.X.S..X.S...S...X.......SX..............X.SSXXXXSXSXX.....SX.TTT...X.ST.......TS...XHC..H.........HH..HHHHHHHHHHHHHHHHHH..C..SSTSSHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH..C....C....SX...STCHCHHHHHHHHHHHHHHHHHHXTTTHHHHHHHHHHHHHCCCCHHHHHHCCC.........................
#=GC seq_cons                          .............................phpslLlasFLp..s..ss..ss.pF+cpLcsLtpp..........................hs.h.....s..............s........-..............s.ELQTDGNRuuH......h.p.u...c.h........hD...sEs..p.........E-..llR.IAtpLApIGDphD+..p..IpsplVNsLstpFhNpsLScE-hpcpLupAlEpLh..p....u....hP...sDMEpEKshLlLAMlLsKKlAspsPSLLpcVFpTTVNaIsQpLhsYlhphs...........................
//
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