KEGG   Pongo abelii (Sumatran orangutan): 100458219
Entry
100458219         CDS       T01416                                 
Symbol
HSD17B6
Name
(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 6
  KO
K13369  17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon00140  Steroid hormone biosynthesis
pon00830  Retinol metabolism
pon01100  Metabolic pathways
pon01240  Biosynthesis of cofactors
Module
pon_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
pon_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:pon00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100458219 (HSD17B6)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    100458219 (HSD17B6)
Enzymes [BR:pon01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     100458219 (HSD17B6)
    1.1.1.105  all-trans-retinol dehydrogenase (NAD+)
     100458219 (HSD17B6)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     100458219 (HSD17B6)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR DUF1776 Tea_helical
Other DBs
NCBI-GeneID: 100458219
NCBI-ProteinID: XP_024113177
Ensembl: ENSPPYG00000004673
UniProt: A0A6D2WXG0
Position
10:54665755..54706006
AA seq 317 aa
MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC
LTEKGAEQLRGQMSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPIT
LCEWLNTEDFMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSK
YGVEAFSDILRREIQHFGVKISIVEPGYFRTGMTNLTQSLERMKQRWKEAPKHIKETYGQ
QYFDAFYSIMKEGLLNCSTNLNLVTDCMEHALTSVHPRTRYSAGWDAKFFFIPLSYLPTS
LADYILTRSWPKPAQAV
NT seq 954 nt   +upstreamnt  +downstreamnt
atgtggctctacctggcggccttcgtgggcctgtactaccttctgcactggtaccgggag
aggcaggtggtgagccacctccaagacaagtatgtctttatcacgggctgtgactcgggc
tttgggaacctgctggccagacagctggatgcacgaggcttgagggtgctggctgcgtgt
ctgacggagaagggggccgagcagctgaggggccagatgtctgacaggctggagacggtg
accctggatgttaccaagatggagagcatcgctgcagctactcagtgggtgaaggagcat
gtgggggacagaggactctggggactggtgaacaacgcaggcattcttacaccaattacc
ttatgtgagtggctgaacactgaggactttatgaatatgctcaaagtgaacctcattggt
gtgatccaggtgaccttgagcatgcttcctttggtgaggagagcacggggaagaattgtc
aatgtctccagcattctgggaagagttgctttctttgtaggaggctactgtgtctccaag
tatggagtggaagccttttcagatattctgaggcgtgagattcaacattttggggtgaaa
atcagcatagttgaacctggctacttcagaacgggaatgacaaacctgacacagtcctta
gagcgaatgaagcaaagatggaaagaagcccccaagcacattaaggagacctatggacag
cagtattttgatgccttttacagtatcatgaaggaagggctgttgaattgtagcacaaac
ctgaacctggtcactgactgcatggaacatgctctgacatcggtgcatccgcgaactcga
tattcagctggctgggatgctaaatttttcttcatccctctatcttatttacctacatca
ctggcagactacattttgactagatcttggcccaaaccagcccaggcagtctaa

  All links  
Gene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (5)   
   Pfam (5)   
All databases (14)   

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