KEGG   Pan paniscus (bonobo): 100967294
Entry
100967294         CDS       T02283                                 

Gene name
IL3
Definition
(RefSeq) interleukin 3
  KO
K04736  interleukin 3
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04210  Apoptosis
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps04664  Fc epsilon RI signaling pathway
pps05200  Pathways in cancer
pps05202  Transcriptional misregulation in cancer
pps05221  Acute myeloid leukemia
pps05310  Asthma
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100967294 (IL3)
   04151 PI3K-Akt signaling pathway
    100967294 (IL3)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100967294 (IL3)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    100967294 (IL3)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100967294 (IL3)
   04664 Fc epsilon RI signaling pathway
    100967294 (IL3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100967294 (IL3)
   05202 Transcriptional misregulation in cancer
    100967294 (IL3)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    100967294 (IL3)
  09163 Immune disease
   05310 Asthma
    100967294 (IL3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100967294 (IL3)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100967294 (IL3)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100967294 (IL3)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Cytokines
   100967294 (IL3)
SSDB
Motif
Pfam: IL3 Ldl_recept_b
Other DBs
NCBI-GeneID: 100967294
NCBI-ProteinID: XP_003829364
UniProt: A0A2R9B411
Position
5
AA seq 154 aa
MSRLPVLILLLLQLLVRPGLQAPMTQTTSLKTSWVNCSNMIDEIITHLKQPPLPLLDFNN
LNGEDQDILMENNLRRPNLEAFNRAVKSLQNASAIESILKNLLPCLPLATAAPTRHPIRI
KDGDWNEFRRKLTFYLKTLENAQAQQTTLSLAIF
NT seq 465 nt   +upstreamnt  +downstreamnt
atgagccgcctgcccgtcctgatcctgctcctgctccaactcctggtccgccccggactc
caagctcccatgacccagacaacgtccttgaagacaagctgggttaactgctctaacatg
atcgatgaaattataacacacttaaagcagccacctttgcctttgctggacttcaacaac
ctcaatggggaagaccaagacattctgatggaaaataaccttcgaaggccaaacctggag
gcattcaacagggctgtcaagagtttacagaacgcatcagcaattgagagcattcttaaa
aatctcctgccatgtctgcccctggccacggccgcacccacgcgacatccaatccgtatc
aaggacggtgactggaatgaattccggaggaaactgacattctatctgaaaacccttgag
aatgcgcaggctcaacagacgactttgagcctcgcgatcttttga

KEGG   Pan paniscus (bonobo): 100967539
Entry
100967539         CDS       T02283                                 

Definition
(RefSeq) interferon alpha-21
  KO
K05414  interferon alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05320  Autoimmune thyroid disease
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100967539
   04151 PI3K-Akt signaling pathway
    100967539
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100967539
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100967539
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100967539
   04621 NOD-like receptor signaling pathway
    100967539
   04622 RIG-I-like receptor signaling pathway
    100967539
   04623 Cytosolic DNA-sensing pathway
    100967539
   04650 Natural killer cell mediated cytotoxicity
    100967539
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100967539
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100967539
   05161 Hepatitis B
    100967539
   05160 Hepatitis C
    100967539
   05171 Coronavirus disease - COVID-19
    100967539
   05164 Influenza A
    100967539
   05162 Measles
    100967539
   05168 Herpes simplex virus 1 infection
    100967539
   05163 Human cytomegalovirus infection
    100967539
   05167 Kaposi sarcoma-associated herpesvirus infection
    100967539
   05169 Epstein-Barr virus infection
    100967539
   05165 Human papillomavirus infection
    100967539
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100967539
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100967539
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100967539
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100967539
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100967539
SSDB
Motif
Pfam: Interferon
Other DBs
NCBI-GeneID: 100967539
NCBI-ProteinID: XP_003830713
UniProt: A0A2R9AYW7
Position
9
AA seq 189 aa
MALSFSLLMAVLVLSYKSICSLGCALPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
FQERLRRKE
NT seq 570 nt   +upstreamnt  +downstreamnt
atggccctgtccttttctttactgatggccgtgctggtgctcagctacaaatccatctgt
tctctgggctgtgctctgcctcagacccacagcctgggtaataggagggccttgatactc
ctggcacaaatgggaagaatctctcctttctcctgcctgaaggacagacatgactttgga
ttcccccaggaggagtttgatggcaaccagttccagaaggctcaagccatctctgtcctc
catgagatgatccagcagaccttcaatctcttcagcacaaaggactcatctgctacttgg
gaacagagcctcctagaaaaattttccactgaacttaaccagcagctgaatgacctggaa
gcctgcgtgatacaggaggttggggtggaagagactcccctgatgaatgtggactccatc
ctggctgtgaagaaatacttccaaagaatcactctttatctaacagagaagaaatacagc
ccttgtgcctgggaggttgtcagagcagaaattatgagatccttctctttatcaaaaatt
tttcaagaaagattaaggaggaaggaatga

KEGG   Pan paniscus (bonobo): 100967827
Entry
100967827         CDS       T02283                                 

Gene name
IL6
Definition
(RefSeq) interleukin 6
  KO
K05405  interleukin 6
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01521  EGFR tyrosine kinase inhibitor resistance
pps01523  Antifolate resistance
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04066  HIF-1 signaling pathway
pps04068  FoxO signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04218  Cellular senescence
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04625  C-type lectin receptor signaling pathway
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps04657  IL-17 signaling pathway
pps04659  Th17 cell differentiation
pps04668  TNF signaling pathway
pps04672  Intestinal immune network for IgA production
pps04931  Insulin resistance
pps04932  Non-alcoholic fatty liver disease
pps04933  AGE-RAGE signaling pathway in diabetic complications
pps05010  Alzheimer disease
pps05020  Prion disease
pps05022  Pathways of neurodegeneration - multiple diseases
pps05132  Salmonella infection
pps05133  Pertussis
pps05134  Legionellosis
pps05135  Yersinia infection
pps05142  Chagas disease
pps05143  African trypanosomiasis
pps05144  Malaria
pps05146  Amoebiasis
pps05152  Tuberculosis
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05166  Human T-cell leukemia virus 1 infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05202  Transcriptional misregulation in cancer
pps05321  Inflammatory bowel disease
pps05323  Rheumatoid arthritis
pps05332  Graft-versus-host disease
pps05410  Hypertrophic cardiomyopathy
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100967827 (IL6)
   04668 TNF signaling pathway
    100967827 (IL6)
   04066 HIF-1 signaling pathway
    100967827 (IL6)
   04068 FoxO signaling pathway
    100967827 (IL6)
   04151 PI3K-Akt signaling pathway
    100967827 (IL6)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100967827 (IL6)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100967827 (IL6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    100967827 (IL6)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100967827 (IL6)
   04620 Toll-like receptor signaling pathway
    100967827 (IL6)
   04621 NOD-like receptor signaling pathway
    100967827 (IL6)
   04623 Cytosolic DNA-sensing pathway
    100967827 (IL6)
   04625 C-type lectin receptor signaling pathway
    100967827 (IL6)
   04659 Th17 cell differentiation
    100967827 (IL6)
   04657 IL-17 signaling pathway
    100967827 (IL6)
   04672 Intestinal immune network for IgA production
    100967827 (IL6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100967827 (IL6)
   05202 Transcriptional misregulation in cancer
    100967827 (IL6)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100967827 (IL6)
   05161 Hepatitis B
    100967827 (IL6)
   05171 Coronavirus disease - COVID-19
    100967827 (IL6)
   05164 Influenza A
    100967827 (IL6)
   05162 Measles
    100967827 (IL6)
   05168 Herpes simplex virus 1 infection
    100967827 (IL6)
   05163 Human cytomegalovirus infection
    100967827 (IL6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100967827 (IL6)
   05169 Epstein-Barr virus infection
    100967827 (IL6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100967827 (IL6)
   05135 Yersinia infection
    100967827 (IL6)
   05133 Pertussis
    100967827 (IL6)
   05134 Legionellosis
    100967827 (IL6)
   05152 Tuberculosis
    100967827 (IL6)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100967827 (IL6)
   05144 Malaria
    100967827 (IL6)
   05142 Chagas disease
    100967827 (IL6)
   05143 African trypanosomiasis
    100967827 (IL6)
  09163 Immune disease
   05323 Rheumatoid arthritis
    100967827 (IL6)
   05321 Inflammatory bowel disease
    100967827 (IL6)
   05332 Graft-versus-host disease
    100967827 (IL6)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100967827 (IL6)
   05020 Prion disease
    100967827 (IL6)
   05022 Pathways of neurodegeneration - multiple diseases
    100967827 (IL6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100967827 (IL6)
   05410 Hypertrophic cardiomyopathy
    100967827 (IL6)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100967827 (IL6)
   04931 Insulin resistance
    100967827 (IL6)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100967827 (IL6)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100967827 (IL6)
   01523 Antifolate resistance
    100967827 (IL6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100967827 (IL6)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100967827 (IL6)
SSDB
Motif
Pfam: IL6 IL11 IL23 Phage_int_SAM_1 GCSF
Other DBs
NCBI-GeneID: 100967827
NCBI-ProteinID: XP_008958307
Position
7
AA seq 212 aa
MNSVSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI
LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL
EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ
AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
NT seq 639 nt   +upstreamnt  +downstreamnt
atgaactccgtctccacaagcgccttcggtccagttgccttctccctggggctgctcctg
gtgttgcctgctgccttccctgccccagtacccccaggagaagattccaaagatgtagcc
gccccacacagacagccactcacctcttcagaacgaattgacaaacaaattcggtacatc
ctcgacggcatctcagccctgagaaaggagacatgtaacaagagtaacatgtgtgaaagc
agcaaagaggcactggcagaaaacaacctgaaccttccaaagatggctgaaaaagatgga
tgcttccaatctggattcaatgaggagacttgcctggtgaaaatcatcactggtcttttg
gagtttgaggtatacctagagtacctccagaacagatttgagagtagtgaggaacaagcc
agagctgtgcagatgagtacaaaagtcctgatccagttcctgcagaaaaaggcaaagaat
ctagatgcaataaccacccctgacccaaccacaaatgccagcctgctgacgaagctgcag
gcacagaaccagtggctgcaggacatgacaactcatctcatcctgcgcagctttaaggag
ttcctgcagtccagcctgagggctcttcggcaaatgtag

KEGG   Pan paniscus (bonobo): 100968231
Entry
100968231         CDS       T02283                                 

Definition
(RefSeq) interferon alpha-17
  KO
K05414  interferon alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05320  Autoimmune thyroid disease
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100968231
   04151 PI3K-Akt signaling pathway
    100968231
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100968231
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100968231
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100968231
   04621 NOD-like receptor signaling pathway
    100968231
   04622 RIG-I-like receptor signaling pathway
    100968231
   04623 Cytosolic DNA-sensing pathway
    100968231
   04650 Natural killer cell mediated cytotoxicity
    100968231
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100968231
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100968231
   05161 Hepatitis B
    100968231
   05160 Hepatitis C
    100968231
   05171 Coronavirus disease - COVID-19
    100968231
   05164 Influenza A
    100968231
   05162 Measles
    100968231
   05168 Herpes simplex virus 1 infection
    100968231
   05163 Human cytomegalovirus infection
    100968231
   05167 Kaposi sarcoma-associated herpesvirus infection
    100968231
   05169 Epstein-Barr virus infection
    100968231
   05165 Human papillomavirus infection
    100968231
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100968231
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100968231
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100968231
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100968231
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100968231
SSDB
Motif
Pfam: Interferon iSTAND
Other DBs
NCBI-GeneID: 100968231
NCBI-ProteinID: XP_003830714
UniProt: A0A2R8ZES4
Position
9
AA seq 189 aa
MALSFSLLMAVLVLSYKSICSLGCDLPQTHNLGNRRALILLAQMGRISPFSCLKDRHDFG
FPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTERKYSPCAWEVVRAEIMRSLSFSTN
LQKRLRRKD
NT seq 570 nt   +upstreamnt  +downstreamnt
atggccctgtccttttctttactgatggccgtgctggtgctcagctacaaatccatctgt
tctctgggctgtgatctgcctcagacccacaacctgggtaataggagggccttgatactc
ctggcacaaatgggaagaatctctcctttctcctgcctgaaggacagacatgatttcgga
ttcccccaggaggagtttgatggcaaccagttccagaagactcaagccatctctgtcctc
catgagatgatccagcagaccttcaatctcttcagcacagaggactcatctgctgcttgg
gaacagagcctcctagaaaaattttccactgaactttaccagcaactgaatgacctggaa
gcatgtgtgatacaggaggttggggtggaagagactcccctgatgaatgaggactccatc
ctggctgtgaggaaatacttccaaagaatcactctttatctaacagagaggaaatacagc
ccttgtgcctgggaggttgtcagagcagaaatcatgagatccctctcgttttcaacaaac
ttgcaaaaaagattaaggaggaaggattga

KEGG   Pan paniscus (bonobo): 100968579
Entry
100968579         CDS       T02283                                 

Definition
(RefSeq) interferon alpha-7
  KO
K05414  interferon alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05320  Autoimmune thyroid disease
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100968579
   04151 PI3K-Akt signaling pathway
    100968579
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100968579
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100968579
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100968579
   04621 NOD-like receptor signaling pathway
    100968579
   04622 RIG-I-like receptor signaling pathway
    100968579
   04623 Cytosolic DNA-sensing pathway
    100968579
   04650 Natural killer cell mediated cytotoxicity
    100968579
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100968579
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100968579
   05161 Hepatitis B
    100968579
   05160 Hepatitis C
    100968579
   05171 Coronavirus disease - COVID-19
    100968579
   05164 Influenza A
    100968579
   05162 Measles
    100968579
   05168 Herpes simplex virus 1 infection
    100968579
   05163 Human cytomegalovirus infection
    100968579
   05167 Kaposi sarcoma-associated herpesvirus infection
    100968579
   05169 Epstein-Barr virus infection
    100968579
   05165 Human papillomavirus infection
    100968579
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100968579
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100968579
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100968579
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100968579
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100968579
SSDB
Motif
Pfam: Interferon iSTAND
Other DBs
NCBI-GeneID: 100968579
NCBI-ProteinID: XP_003830715
UniProt: A0A2R9AR25
Position
9
AA seq 189 aa
MALSFSLLMAMLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHEFR
FPEEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSFSTN
LKKGLRRKD
NT seq 570 nt   +upstreamnt  +downstreamnt
atggccctgtccttttctttactgatggccatgctggtactcagctacaaatccatctgc
tctcttggctgtgatctgcctcagacccacagcctgggtaataggagggccttgatactc
ctggcacaaatgggaagaatctctcctttctcctgcttgaaggacagacatgaattcaga
ttcccagaggaggagtttgatggcaaccagttccagaagactcaagccatctctgtcctc
cacgagatgatccagcagaccttcaatctcttcagcacagaggactcatctgctgcttgg
gaacagagcctcctagaaaaattttccactgaactttaccagcaactgaatgacctggaa
gcatgtgtgatacaggaggttggggtggaagagactcccctgatgaatgaggactccatc
ctggctgtgaggaaatacttccaaagaatcactctttatctaacagagaagaaatacagc
ccttgtgcctgggaggttgtcagagcagaaatcatgagatccttctctttttcaacaaac
ttgaaaaaaggattaaggaggaaggattga

KEGG   Pan paniscus (bonobo): 100968923
Entry
100968923         CDS       T02283                                 

Definition
(RefSeq) interferon alpha-17-like
  KO
K05414  interferon alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05320  Autoimmune thyroid disease
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100968923
   04151 PI3K-Akt signaling pathway
    100968923
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100968923
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100968923
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100968923
   04621 NOD-like receptor signaling pathway
    100968923
   04622 RIG-I-like receptor signaling pathway
    100968923
   04623 Cytosolic DNA-sensing pathway
    100968923
   04650 Natural killer cell mediated cytotoxicity
    100968923
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100968923
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100968923
   05161 Hepatitis B
    100968923
   05160 Hepatitis C
    100968923
   05171 Coronavirus disease - COVID-19
    100968923
   05164 Influenza A
    100968923
   05162 Measles
    100968923
   05168 Herpes simplex virus 1 infection
    100968923
   05163 Human cytomegalovirus infection
    100968923
   05167 Kaposi sarcoma-associated herpesvirus infection
    100968923
   05169 Epstein-Barr virus infection
    100968923
   05165 Human papillomavirus infection
    100968923
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100968923
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100968923
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100968923
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100968923
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100968923
SSDB
Motif
Pfam: Interferon iSTAND
Other DBs
NCBI-GeneID: 100968923
NCBI-ProteinID: XP_003830716
Position
9
AA seq 172 aa
MALSFSLLMAVLVLSYKSICSLGCDLPQTHNLGNRRALILLAQMGRISPFSCLKDRHDFG
FPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTERKYSPCAWEVVRAEIM
NT seq 516 nt   +upstreamnt  +downstreamnt
atggccctgtccttttctttactgatggccgtgctggtgctcagctacaaatccatctgt
tctctgggctgtgatctgcctcagacccacaacctgggtaataggagggccttgatactc
ctggcacaaatgggaagaatctctcctttctcctgcctgaaggacagacatgatttcgga
ttcccccaggaggagtttgatggcaaccagttccagaagactcaagccatctctgtcctc
catgagatgatccagcagaccttcaatctcttcagcacagaggactcatctgctgcttgg
gaacagagcctcctagaaaaattttccactgaactttaccagcaactgaatgacctggaa
gcatgtgtgatacaggaggttggggtggaagagactcccctgatgaatgaggactccatc
ctggctgtgaggaaatacttccaaagaatcactctttatctaacagagaggaaatacagc
ccttgtgcctgggaggttgtcagagcagaaatcatg

KEGG   Pan paniscus (bonobo): 100969275
Entry
100969275         CDS       T02283                                 

Definition
(RefSeq) interferon alpha-10-like
  KO
K05414  interferon alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05320  Autoimmune thyroid disease
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100969275
   04151 PI3K-Akt signaling pathway
    100969275
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100969275
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100969275
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100969275
   04621 NOD-like receptor signaling pathway
    100969275
   04622 RIG-I-like receptor signaling pathway
    100969275
   04623 Cytosolic DNA-sensing pathway
    100969275
   04650 Natural killer cell mediated cytotoxicity
    100969275
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100969275
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100969275
   05161 Hepatitis B
    100969275
   05160 Hepatitis C
    100969275
   05171 Coronavirus disease - COVID-19
    100969275
   05164 Influenza A
    100969275
   05162 Measles
    100969275
   05168 Herpes simplex virus 1 infection
    100969275
   05163 Human cytomegalovirus infection
    100969275
   05167 Kaposi sarcoma-associated herpesvirus infection
    100969275
   05169 Epstein-Barr virus infection
    100969275
   05165 Human papillomavirus infection
    100969275
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100969275
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100969275
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100969275
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100969275
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100969275
SSDB
Motif
Pfam: Interferon iSTAND
Other DBs
NCBI-GeneID: 100969275
NCBI-ProteinID: XP_003830717
Position
9
AA seq 189 aa
MALSFSLLMAMLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFYIELFQQLNDLE
ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
LKKGLRRKD
NT seq 570 nt   +upstreamnt  +downstreamnt
atggccctgtccttttctttactgatggccatgctggtgctcagctacaaatccatctgt
tctctgggctgtgatctgcctcagacccacagcctgggtaataggagggccttgatactc
ctggcacaaatgggaagaatctctcctttctcctgcctgaaggacagacatgactttgga
ttcccccaggaggagtttgatggcaaccagttccagaaggctcaagccatctctgtcctc
catgagatgatccagcagaccttcaatctcttcagcacagaggactcatctgctgcttgg
gaacagagcctcctagaaaaattctacattgaacttttccagcaactgaatgacctggaa
gcctgtgtgatacaggaggttggggtggaagagactcccttgatgaatgaggactctatc
ctggctgtgaggaaatactttcaaagaatcactctttatctgatggagaagaaatacagc
ccttgtgcctgggaggttgtcagagcagaaatcatgagatccttctctttttcaacaaac
ttgaaaaagggattaaggaggaaggattga

KEGG   Pan paniscus (bonobo): 100969624
Entry
100969624         CDS       T02283                                 

Definition
(RefSeq) interferon alpha-16
  KO
K05414  interferon alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05320  Autoimmune thyroid disease
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100969624
   04151 PI3K-Akt signaling pathway
    100969624
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100969624
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100969624
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100969624
   04621 NOD-like receptor signaling pathway
    100969624
   04622 RIG-I-like receptor signaling pathway
    100969624
   04623 Cytosolic DNA-sensing pathway
    100969624
   04650 Natural killer cell mediated cytotoxicity
    100969624
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100969624
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100969624
   05161 Hepatitis B
    100969624
   05160 Hepatitis C
    100969624
   05171 Coronavirus disease - COVID-19
    100969624
   05164 Influenza A
    100969624
   05162 Measles
    100969624
   05168 Herpes simplex virus 1 infection
    100969624
   05163 Human cytomegalovirus infection
    100969624
   05167 Kaposi sarcoma-associated herpesvirus infection
    100969624
   05169 Epstein-Barr virus infection
    100969624
   05165 Human papillomavirus infection
    100969624
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100969624
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100969624
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100969624
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100969624
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100969624
SSDB
Motif
Pfam: Interferon APC1_C iSTAND
Other DBs
NCBI-GeneID: 100969624
NCBI-ProteinID: XP_003830718
Position
9
AA seq 189 aa
MALSFSLLMAVLVLSYKSICSLGCALPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
FPQEEFDGNQFQKAQAISVFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
LQKRLRRKD
NT seq 570 nt   +upstreamnt  +downstreamnt
atggccctgtccttttctttactgatggccgtgctggtgctcagctacaaatccatctgt
tctctgggctgtgctctgcctcagactcacagcctgggtaataggagggccttgatactc
ctggcacaaatgggaagaatctctcctttctcctgcctgaaggacagacatgactttgga
ttcccccaggaggagtttgatggcaaccagttccagaaggctcaagccatctctgtcttc
catgagatgatccagcagaccttcaatctcttcagcacaaaggactcatctgctgcttgg
gatgagaccctcctagacaaattctacattgaacttttccagcaactgaatgacctagaa
gcatgtgtgatacaggaggttggggtggaagagactcccctgatgaatgaggactccatc
ctggctgtgaggaaatacttccaaagaatcactctttatctgatggagaagaaatacagc
ccttgtgcctgggaggttgtcagagcagaaatcatgagatccttctctttttcaacaaac
ttgcaaaaaagattaaggaggaaggattga

KEGG   Pan paniscus (bonobo): 100970300
Entry
100970300         CDS       T02283                                 

Definition
(RefSeq) interferon alpha-17-like
  KO
K05414  interferon alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05320  Autoimmune thyroid disease
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100970300
   04151 PI3K-Akt signaling pathway
    100970300
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100970300
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100970300
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100970300
   04621 NOD-like receptor signaling pathway
    100970300
   04622 RIG-I-like receptor signaling pathway
    100970300
   04623 Cytosolic DNA-sensing pathway
    100970300
   04650 Natural killer cell mediated cytotoxicity
    100970300
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100970300
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100970300
   05161 Hepatitis B
    100970300
   05160 Hepatitis C
    100970300
   05171 Coronavirus disease - COVID-19
    100970300
   05164 Influenza A
    100970300
   05162 Measles
    100970300
   05168 Herpes simplex virus 1 infection
    100970300
   05163 Human cytomegalovirus infection
    100970300
   05167 Kaposi sarcoma-associated herpesvirus infection
    100970300
   05169 Epstein-Barr virus infection
    100970300
   05165 Human papillomavirus infection
    100970300
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100970300
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100970300
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100970300
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100970300
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100970300
SSDB
Motif
Pfam: Interferon iSTAND
Other DBs
NCBI-GeneID: 100970300
NCBI-ProteinID: XP_003830719
UniProt: A0A2R8Z8Q0
Position
9
AA seq 189 aa
MALSFSLLMAMLVLSYKSICSLGCDLPQTHNLGNRRALILLAQMRRISPFSCLKDRHDFG
LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
LQKRLRRKD
NT seq 570 nt   +upstreamnt  +downstreamnt
atggccctgtccttttctttactgatggccatgctggtgctcagctacaaatccatctgt
tctctaggctgtgatctgcctcagacccacaacctgggtaataggagggccttgatactc
ctggcacaaatgcgaagaatctctcctttctcctgcctgaaggacagacatgactttgga
cttccccaggaggagtttgatggcaaccagttccagaagactcaagccatctctgtcctc
catgagatgatccagcagaccttcaatctcttcagcacagaggactcatctgctgcttgg
gaacagagcctcctagaaaaattttccactgaactttaccagcaactgaataacctggaa
gcatgtgtgatacaggaggttggggtggaagagactcccctgatgaatgaggactccatc
ctggctgtgaagaaatacttccaaagaatcactctttatctaacagagaagaaatacagc
ccttgtgcctgggaggttgtcagagcagaaatcatgagatccctctcgttttcaacaaac
ttgcaaaaaagattaaggaggaaggattga

KEGG   Pan paniscus (bonobo): 100970658
Entry
100970658         CDS       T02283                                 

Gene name
IFNA14
Definition
(RefSeq) interferon alpha-14
  KO
K05414  interferon alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05320  Autoimmune thyroid disease
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100970658 (IFNA14)
   04151 PI3K-Akt signaling pathway
    100970658 (IFNA14)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100970658 (IFNA14)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100970658 (IFNA14)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100970658 (IFNA14)
   04621 NOD-like receptor signaling pathway
    100970658 (IFNA14)
   04622 RIG-I-like receptor signaling pathway
    100970658 (IFNA14)
   04623 Cytosolic DNA-sensing pathway
    100970658 (IFNA14)
   04650 Natural killer cell mediated cytotoxicity
    100970658 (IFNA14)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100970658 (IFNA14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100970658 (IFNA14)
   05161 Hepatitis B
    100970658 (IFNA14)
   05160 Hepatitis C
    100970658 (IFNA14)
   05171 Coronavirus disease - COVID-19
    100970658 (IFNA14)
   05164 Influenza A
    100970658 (IFNA14)
   05162 Measles
    100970658 (IFNA14)
   05168 Herpes simplex virus 1 infection
    100970658 (IFNA14)
   05163 Human cytomegalovirus infection
    100970658 (IFNA14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100970658 (IFNA14)
   05169 Epstein-Barr virus infection
    100970658 (IFNA14)
   05165 Human papillomavirus infection
    100970658 (IFNA14)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100970658 (IFNA14)
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100970658 (IFNA14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100970658 (IFNA14)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100970658 (IFNA14)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100970658 (IFNA14)
SSDB
Motif
Pfam: Interferon APC1_C
Other DBs
NCBI-GeneID: 100970658
NCBI-ProteinID: XP_003830720
UniProt: A0A2R8ZDB6
Position
9
AA seq 189 aa
MALPFALMMALVVLSCKSSCSLGCDLSQTHSLNNRRTLMLMTQMRRISPFSCLKDRHDFE
FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKNSSAAWDETLLDKFYIELFQQMNDLE
ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
LQKRLRRKD
NT seq 570 nt   +upstreamnt  +downstreamnt
atggcgttgccctttgctttaatgatggccctggtggtgctcagctgcaagtcaagctgc
tctctgggctgtgatctgtctcaaacccacagcctgaataacaggaggactttgatgctt
atgacacaaatgaggagaatctctcctttctcctgcctgaaggacagacatgactttgaa
tttccccaggaggaatttgatggcaaccagtttcagaaagctcaagccatctctgtcctc
catgagatgatccagcagaccttcaatctcttcagcacaaagaactcatctgctgcttgg
gatgagaccctcctagacaaattctacattgaacttttccagcaaatgaatgacctggaa
gcctgtgtgatacaggaggttggggtggaagagactcccctgatgaatgaggactctatc
ctggctgtgaggaaatactttcaaagaatcactctttatctgatggagaagaaatacagc
ccttgtgcctgggaggttgtcagagcagaaatcatgagatccctctctttttcaacaaac
ttgcaaaaaagattaaggaggaaggattga

KEGG   Pan paniscus (bonobo): 100971303
Entry
100971303         CDS       T02283                                 

Gene name
LIF
Definition
(RefSeq) leukemia inhibitory factor
  KO
K05419  leukemia inhibitory factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04550  Signaling pathways regulating pluripotency of stem cells
pps04630  JAK-STAT signaling pathway
pps04668  TNF signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100971303 (LIF)
   04668 TNF signaling pathway
    100971303 (LIF)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100971303 (LIF)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100971303 (LIF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100971303 (LIF)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  CSF and other factors
   100971303 (LIF)
SSDB
Motif
Pfam: LIF_OSM
Other DBs
NCBI-GeneID: 100971303
NCBI-ProteinID: XP_003812062
UniProt: A0A2R8ZDL6
Position
22
AA seq 202 aa
MKVLAAGVVPLLLVLHWKHGAGSPLPITPVNATCAIRHPCHNNLMNQIRSQLAQLNGSAN
ALFILYYTAQGEPFPNNLDKLCGPNVTDFPPFHANGTEKAKLVELYRIVVYLGTSLGNIT
RDQKILNPSALSLHSKLNATADILRGLLSNVLCRLCSKYHVGHVDVTYGPDTSGKDVFQK
KKLGCQLLGKYKQIIAVLAQAF
NT seq 609 nt   +upstreamnt  +downstreamnt
atgaaggtcttggcggcaggagttgtgcccctgctgttggttctgcactggaaacatggg
gcggggagccccctccccatcacccctgtcaacgccacctgtgccatacgccacccatgt
cacaacaacctcatgaaccagatcaggagccaactggcacagctcaatggcagtgccaat
gccctctttattctctattacacagcccagggggagccgttccccaacaacctggacaag
ctatgtggccccaacgtgacggacttcccgcccttccacgccaacggcacggagaaggcc
aagctggtggagctgtaccgcatagtcgtgtaccttggcacctccctgggcaacatcacc
cgggaccagaagatcctcaaccccagtgccctcagcctccacagcaagctcaacgccacc
gccgacatcctgcgaggcctccttagcaacgtgctgtgccgcctgtgcagcaagtaccac
gtgggccatgtggacgtgacctacggccctgacacctcgggtaaggacgtcttccagaag
aagaagctgggctgtcaactcctggggaagtataagcagatcatcgccgtgttggcccag
gccttctag

KEGG   Pan paniscus (bonobo): 100971653
Entry
100971653         CDS       T02283                                 

Gene name
OSM
Definition
(RefSeq) oncostatin M
  KO
K05418  oncostatin M
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100971653 (OSM)
   04151 PI3K-Akt signaling pathway
    100971653 (OSM)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100971653 (OSM)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100971653 (OSM)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  CSF and other factors
   100971653 (OSM)
SSDB
Motif
Pfam: LIF_OSM
Other DBs
NCBI-GeneID: 100971653
NCBI-ProteinID: XP_003812063
UniProt: A0A2R9A1R8
Position
22
AA seq 252 aa
MGVLLTQRTLLSLVLALLFPSMASMAAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYI
RIQGLDVPKLREHCRERPGAFPSEETLKGLGRRGFLQTLNATLGCVLHRLADLEQRLPKA
QDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTP
ASDAFQRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRRHSPHQALRKGVRRTRPSRK
GKRLMPRGQLPR
NT seq 759 nt   +upstreamnt  +downstreamnt
atgggggtactgctcacacagaggacactgctcagtctggtccttgcactcctgtttcca
agcatggcgagcatggcggctataggcagctgctcgaaagagtaccgcgtgctccttggc
cagctccagaagcagacagatctcatgcaggacaccagcagactcctggacccctatata
cgtatccaaggcctggatgttcctaaactgagagagcactgcagggagcgccccggggcc
ttccccagtgaggagaccctgaaggggctgggcaggcggggcttcctgcagaccctcaat
gccacactgggctgcgtcctgcacagactggccgacttagagcagcgcctccccaaggcc
caggatttggagaggtctgggctgaacatcgaggacttggagaagctgcagatggcgagg
ccgaacatcctcgggctcaggaacaacatctactgcatggcccagctgctggacaactca
gacacggctgagcccacgaaggctggccggggggcctctcagccgcccacccccacccct
gcctcggatgcttttcagcgcaagctggagggctgcaggttcctgcatggctaccatcgc
ttcatgcactcagtggggcgggtcttcagcaagtggggggagagcccgaaccggagccgg
agacacagcccccaccaggccctgaggaagggggtgcgcaggaccagaccctccaggaaa
ggcaagagactcatgcccaggggacagctgccccggtag

KEGG   Pan paniscus (bonobo): 100971675
Entry
100971675         CDS       T02283                                 

Gene name
IFNA6
Definition
(RefSeq) interferon alpha 6
  KO
K05414  interferon alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05320  Autoimmune thyroid disease
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100971675 (IFNA6)
   04151 PI3K-Akt signaling pathway
    100971675 (IFNA6)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100971675 (IFNA6)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100971675 (IFNA6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100971675 (IFNA6)
   04621 NOD-like receptor signaling pathway
    100971675 (IFNA6)
   04622 RIG-I-like receptor signaling pathway
    100971675 (IFNA6)
   04623 Cytosolic DNA-sensing pathway
    100971675 (IFNA6)
   04650 Natural killer cell mediated cytotoxicity
    100971675 (IFNA6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100971675 (IFNA6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100971675 (IFNA6)
   05161 Hepatitis B
    100971675 (IFNA6)
   05160 Hepatitis C
    100971675 (IFNA6)
   05171 Coronavirus disease - COVID-19
    100971675 (IFNA6)
   05164 Influenza A
    100971675 (IFNA6)
   05162 Measles
    100971675 (IFNA6)
   05168 Herpes simplex virus 1 infection
    100971675 (IFNA6)
   05163 Human cytomegalovirus infection
    100971675 (IFNA6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100971675 (IFNA6)
   05169 Epstein-Barr virus infection
    100971675 (IFNA6)
   05165 Human papillomavirus infection
    100971675 (IFNA6)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100971675 (IFNA6)
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100971675 (IFNA6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100971675 (IFNA6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100971675 (IFNA6)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100971675 (IFNA6)
SSDB
Motif
Pfam: Interferon iSTAND
Other DBs
NCBI-GeneID: 100971675
NCBI-ProteinID: XP_003830722
UniProt: A0A2R8ZAA7
Position
9
AA seq 189 aa
MALPFALLMALVVLSCKSSCSLGCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
ACVMQEVWVGETPLMNEDSILAVRKYFQRITLYLTDKKYSPCAWEVVRAEIMRSFSSSRN
LQERLRRKE
NT seq 570 nt   +upstreamnt  +downstreamnt
atggctttgccttttgctttactgatggccctggtggtgctcagctgcaagtcaagctgc
tctctgggctgtgatctgcctcagacccacagcctgggacacaggaggaccatgatgctc
ctggcacaaatgaggagaatctctcttttctcctgtctgaaggacagacacgacttcaga
tttccccaggaggagtttgatggcaaccagttccagaaggctgaagccatctctgtcctc
catgaggtgattcagcagaccttcaacctcttcagcacaaaggactcatctgttgcttgg
gatgagaggcttctagacaaactctatactgaactttaccagcagctgaatgacctggaa
gcctgtgtgatgcaggaggtgtgggtgggagagactcccctaatgaatgaggactccatc
ctggctgtgagaaaatacttccaaagaatcactctctacctgacagacaaaaagtacagc
ccttgtgcctgggaggttgtcagagcagaaatcatgagatccttctcttcatcaagaaac
ttgcaagaaaggttaaggaggaaggaataa

KEGG   Pan paniscus (bonobo): 100971967
Entry
100971967         CDS       T02283                                 

Gene name
TSLP
Definition
(RefSeq) thymic stromal lymphopoietin
  KO
K05436  thymic stromal lymphopoietin
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100971967 (TSLP)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100971967 (TSLP)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100971967 (TSLP)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  CSF and other factors
   100971967 (TSLP)
SSDB
Motif
Pfam: TSLP
Other DBs
NCBI-GeneID: 100971967
NCBI-ProteinID: XP_003826800
UniProt: A0A2R9BKN6
Position
5
AA seq 159 aa
MKCLGQSKKEEVSFRKIFILQLVGLVLTYDFTNCDFEKIKAAYLSTISKDLITYMSGTKS
TEFNNTVSCSNRPHCLTEIQSLTFNPTAGCASLAKEMFAMKTKAALAIWCPGYSETQINA
TQAMKKRRKRKVTTNKCLEQVSQLQGLWRRFNRPLLKQQ
NT seq 480 nt   +upstreamnt  +downstreamnt
atgaagtgtttagggcaaagcaaaaaggaggaagtttctttcaggaaaatcttcatctta
caacttgtagggctggtgttaacttacgacttcactaactgtgactttgagaagattaaa
gcagcctatctcagtactatttctaaagacctgattacatatatgagtgggaccaaaagt
accgagttcaacaacaccgtctcttgtagcaatcggccacattgccttactgaaatccag
agcctaaccttcaatcccaccgccggctgcgcgtcgctcgccaaagaaatgttcgccatg
aaaactaaggctgccttagctatctggtgcccaggctattcggaaactcagataaatgct
actcaggcaatgaagaagaggagaaaaaggaaagtcacaaccaataaatgtctggaacaa
gtgtcacaattacaaggattgtggcgtcgcttcaatcgacctttactgaaacaacagtaa

KEGG   Pan paniscus (bonobo): 100972005
Entry
100972005         CDS       T02283                                 

Definition
(RefSeq) interferon alpha-1/13-like
  KO
K05414  interferon alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05320  Autoimmune thyroid disease
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100972005
   04151 PI3K-Akt signaling pathway
    100972005
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100972005
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100972005
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100972005
   04621 NOD-like receptor signaling pathway
    100972005
   04622 RIG-I-like receptor signaling pathway
    100972005
   04623 Cytosolic DNA-sensing pathway
    100972005
   04650 Natural killer cell mediated cytotoxicity
    100972005
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100972005
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100972005
   05161 Hepatitis B
    100972005
   05160 Hepatitis C
    100972005
   05171 Coronavirus disease - COVID-19
    100972005
   05164 Influenza A
    100972005
   05162 Measles
    100972005
   05168 Herpes simplex virus 1 infection
    100972005
   05163 Human cytomegalovirus infection
    100972005
   05167 Kaposi sarcoma-associated herpesvirus infection
    100972005
   05169 Epstein-Barr virus infection
    100972005
   05165 Human papillomavirus infection
    100972005
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100972005
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100972005
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100972005
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100972005
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100972005
SSDB
Motif
Pfam: Interferon
Other DBs
NCBI-GeneID: 100972005
NCBI-ProteinID: XP_003830723
Position
9
AA seq 189 aa
MASPFALLMALVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSYAAWDEELLDKFCTELYQQLNDLE
ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
LRERLRRKE
NT seq 570 nt   +upstreamnt  +downstreamnt
atggcctcaccctttgctttactgatggccctggtggtgctcagctgcaagtcaagctgc
tctctgggctgtgatctgcctgagacccacagcctggataacaggaggaccttgatgctc
ctggcacaaatgagcagaatctctccttcctcctgtctgatggacagacatgactttgga
tttccccaggaggagtttgatggcaaccagttccagaaggctccagccatctctgtcctc
catgagctgatccagcagatcttcaacctctttaccacaaaagattcatatgctgcttgg
gatgaggaactcctagacaaattctgcactgaactctaccagcagctgaatgacttggaa
gcctgtgtgatgcaggaggagagggtgggagaaactcccctgatgaatgcggactccatc
ttggctgtgaagaaatacttccgaagaatcactctctatctgacagagaagaaatacagc
ccttgtgcctgggaggttgtcagagcagaaatcatgagatccctctctttatcaacaaac
ttgcgagaaagattaaggaggaaggaataa

KEGG   Pan paniscus (bonobo): 100972295
Entry
100972295         CDS       T02283                                 

Gene name
CTF1
Definition
(RefSeq) cardiotrophin 1
  KO
K05422  cardiotrophin 1
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100972295 (CTF1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100972295 (CTF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100972295 (CTF1)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  CSF and other factors
   100972295 (CTF1)
SSDB
Other DBs
NCBI-GeneID: 100972295
NCBI-ProteinID: XP_008957910
Position
16
AA seq 124 aa
MSRREGSLEDPQTDSSVSLLPHLEAKIRQTHSLAHLLTKYAEQLLQEYVQLQGDPFGLPS
FSPPRLPVAGLSAPAPSHAGLPVHERLRLDAPAKVLGLRVCGLYREWLSRTEGDLGQLLP
GGSA
NT seq 375 nt   +upstreamnt  +downstreamnt
atgagccggagggagggaagtctggaagacccccagactgattcctcagtctcacttctt
ccccacttggaggccaagatccgtcagacacacagccttgcgcacctcctcaccaaatac
gctgagcagctgctccaggaatatgtgcagctccagggagaccccttcgggctgcccagc
ttctcgccgccgcggctgccggtggccggcctgagcgccccggctccgagccatgcgggg
ttgccagtgcacgagcggctgcggctggacgcgcccgccaaggtgctggggctccgcgtt
tgcggcctctaccgcgagtggctgagccgcaccgagggcgacctgggccagctgctgccc
gggggctcggcctga

KEGG   Pan paniscus (bonobo): 100972354
Entry
100972354         CDS       T02283                                 

Gene name
IFNA2
Definition
(RefSeq) interferon alpha 2
  KO
K05414  interferon alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05320  Autoimmune thyroid disease
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100972354 (IFNA2)
   04151 PI3K-Akt signaling pathway
    100972354 (IFNA2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100972354 (IFNA2)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100972354 (IFNA2)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100972354 (IFNA2)
   04621 NOD-like receptor signaling pathway
    100972354 (IFNA2)
   04622 RIG-I-like receptor signaling pathway
    100972354 (IFNA2)
   04623 Cytosolic DNA-sensing pathway
    100972354 (IFNA2)
   04650 Natural killer cell mediated cytotoxicity
    100972354 (IFNA2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100972354 (IFNA2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100972354 (IFNA2)
   05161 Hepatitis B
    100972354 (IFNA2)
   05160 Hepatitis C
    100972354 (IFNA2)
   05171 Coronavirus disease - COVID-19
    100972354 (IFNA2)
   05164 Influenza A
    100972354 (IFNA2)
   05162 Measles
    100972354 (IFNA2)
   05168 Herpes simplex virus 1 infection
    100972354 (IFNA2)
   05163 Human cytomegalovirus infection
    100972354 (IFNA2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100972354 (IFNA2)
   05169 Epstein-Barr virus infection
    100972354 (IFNA2)
   05165 Human papillomavirus infection
    100972354 (IFNA2)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100972354 (IFNA2)
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100972354 (IFNA2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100972354 (IFNA2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100972354 (IFNA2)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100972354 (IFNA2)
SSDB
Motif
Pfam: Interferon CBF iSTAND APC1_C DDHD ORF6C
Other DBs
NCBI-GeneID: 100972354
NCBI-ProteinID: XP_003830724
Position
9
AA seq 188 aa
MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGNRRTLMLLAQMRRISLFSCLKDRHDFG
FPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEA
CVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCSWEVVRAEIMRSFSLSTNL
QESLRSKE
NT seq 567 nt   +upstreamnt  +downstreamnt
atggccttgacctttgctttactggtggccctcctggtgctcagctgcaagtcaagctgc
tctgtgggctgtgatctgcctcaaacccacagcctgggtaacaggaggaccttgatgctc
ctggcacagatgaggagaatctctcttttctcctgcttgaaggacagacatgactttgga
tttccccaggaggagtttggcaaccagttccaaaaggctgaaaccatccctgtcctccat
gagatgatccagcagatcttcaatctcttcagcacaaaggactcatctgctgcttgggat
gagaccctcctagacaaattctacactgaactctaccagcagctgaatgacctggaagcc
tgtgtgatacagggggtgggggtgacagagactcccctgatgaaggaggactccattctg
gctgtgaggaaatacttccaaagaatcactctctatctgaaagagaagaaatacagccct
tgttcctgggaggttgtcagagcagaaatcatgagatctttttctttgtcaacaaacttg
caagaaagtttaagaagtaaggaatga

KEGG   Pan paniscus (bonobo): 100972565
Entry
100972565         CDS       T02283                                 

Gene name
IL9
Definition
(RefSeq) interleukin 9
  KO
K05432  interleukin 9
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps05310  Asthma
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100972565 (IL9)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100972565 (IL9)
 09160 Human Diseases
  09163 Immune disease
   05310 Asthma
    100972565 (IL9)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100972565 (IL9)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100972565 (IL9)
SSDB
Other DBs
NCBI-GeneID: 100972565
NCBI-ProteinID: XP_003829303
UniProt: A0A2R9ANX9
Position
5
AA seq 144 aa
MLLAMVLTSALLLCSVAGQGCPTLAGILDINFLINKMQEDPASKCHCSANVTSCLCLAIP
SDNCTRPCFSERLSQMTNTTMQTRYPLIFSRVKKSVEVLKNNKCPYFSCEQPCNQTTAGN
ALTFLKSLLEIFQKEKMRGMRGKI
NT seq 435 nt   +upstreamnt  +downstreamnt
atgcttctggccatggtccttacctctgccctgctcctgtgctccgtggcaggccagggg
tgtccaaccttggcggggatcctggacatcaacttcctcatcaacaagatgcaggaagat
ccagcttccaagtgccactgcagtgctaatgtgaccagttgtctctgtctggccattccc
tctgacaactgcaccagaccatgcttcagtgagagactgtctcagatgaccaataccacc
atgcaaacaagatacccactgattttcagtcgggtgaaaaaatcagttgaagtactaaag
aacaacaagtgtccatatttttcctgtgaacagccatgcaaccaaaccacggcaggcaac
gcgctgacatttctgaagagtcttctggaaattttccagaaagaaaagatgagagggatg
agaggcaagatatga

KEGG   Pan paniscus (bonobo): 100972691
Entry
100972691         CDS       T02283                                 

Gene name
IFNA8
Definition
(RefSeq) interferon alpha 8
  KO
K05414  interferon alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05320  Autoimmune thyroid disease
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100972691 (IFNA8)
   04151 PI3K-Akt signaling pathway
    100972691 (IFNA8)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100972691 (IFNA8)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100972691 (IFNA8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100972691 (IFNA8)
   04621 NOD-like receptor signaling pathway
    100972691 (IFNA8)
   04622 RIG-I-like receptor signaling pathway
    100972691 (IFNA8)
   04623 Cytosolic DNA-sensing pathway
    100972691 (IFNA8)
   04650 Natural killer cell mediated cytotoxicity
    100972691 (IFNA8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100972691 (IFNA8)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100972691 (IFNA8)
   05161 Hepatitis B
    100972691 (IFNA8)
   05160 Hepatitis C
    100972691 (IFNA8)
   05171 Coronavirus disease - COVID-19
    100972691 (IFNA8)
   05164 Influenza A
    100972691 (IFNA8)
   05162 Measles
    100972691 (IFNA8)
   05168 Herpes simplex virus 1 infection
    100972691 (IFNA8)
   05163 Human cytomegalovirus infection
    100972691 (IFNA8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100972691 (IFNA8)
   05169 Epstein-Barr virus infection
    100972691 (IFNA8)
   05165 Human papillomavirus infection
    100972691 (IFNA8)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100972691 (IFNA8)
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100972691 (IFNA8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100972691 (IFNA8)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100972691 (IFNA8)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100972691 (IFNA8)
SSDB
Motif
Pfam: Interferon
Other DBs
NCBI-GeneID: 100972691
NCBI-ProteinID: XP_003830725
UniProt: A0A2R8ZIR7
Position
9
AA seq 189 aa
MALTFYLLVALVVLSYKSFSSLGCDLPQTHSLGNRRALVLLAQMKRISPFSCLKDRHDFE
FPQEEFDDKQFQKAQAISVLHEMIQQTFNLFSTKDSSAALDETLLDEFYIELDQQLNDLE
SCVMQEVGVIESPLMYEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSIN
LQKRLKSKE
NT seq 570 nt   +upstreamnt  +downstreamnt
atggccttgactttttatttactggtggccctagtggtgctcagctacaagtcattcagc
tctctgggctgtgatctgcctcagacccacagcctgggtaacaggagggccttggtcctc
ctggcacaaatgaaaagaatctctcctttctcctgcctgaaggacagacatgactttgaa
ttcccccaggaggagtttgatgataaacaattccagaaggctcaagccatctctgtcctc
catgagatgatccagcagaccttcaacctcttcagcacaaaggactcatctgctgctttg
gatgagacccttctagatgaattctacatcgaacttgaccagcagctgaatgacctggag
tcctgtgtgatgcaggaagtgggggtgatagagtctcccctgatgtacgaggactccatc
ctggctgtgaggaaatacttccaaagaatcactctatatctgacagagaagaaatacagc
ccttgtgcctgggaggttgtcagagcagaaatcatgagatccttctctttatcaatcaac
ttgcaaaaaagattgaagagtaaggaatga

KEGG   Pan paniscus (bonobo): 100973049
Entry
100973049         CDS       T02283                                 

Definition
(RefSeq) interferon alpha-1/13
  KO
K05414  interferon alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05320  Autoimmune thyroid disease
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100973049
   04151 PI3K-Akt signaling pathway
    100973049
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100973049
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100973049
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100973049
   04621 NOD-like receptor signaling pathway
    100973049
   04622 RIG-I-like receptor signaling pathway
    100973049
   04623 Cytosolic DNA-sensing pathway
    100973049
   04650 Natural killer cell mediated cytotoxicity
    100973049
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100973049
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100973049
   05161 Hepatitis B
    100973049
   05160 Hepatitis C
    100973049
   05171 Coronavirus disease - COVID-19
    100973049
   05164 Influenza A
    100973049
   05162 Measles
    100973049
   05168 Herpes simplex virus 1 infection
    100973049
   05163 Human cytomegalovirus infection
    100973049
   05167 Kaposi sarcoma-associated herpesvirus infection
    100973049
   05169 Epstein-Barr virus infection
    100973049
   05165 Human papillomavirus infection
    100973049
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100973049
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100973049
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100973049
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100973049
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100973049
SSDB
Motif
Pfam: Interferon iSTAND CBF
Other DBs
NCBI-GeneID: 100973049
NCBI-ProteinID: XP_003830726
Position
9
AA seq 189 aa
MASPFALLMALVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEELLDKFCTELYQQLNDLE
ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
LQERLRRKE
NT seq 570 nt   +upstreamnt  +downstreamnt
atggcctcaccctttgctttactgatggccctggtggtgctcagctgcaagtcaagctgc
tctctgggctgtgatctgcctgagacccacagcctggataacaggaggaccttgatgctc
ctggcacaaatgagcagaatctctccttcctcctgtctgatggacagacatgactttgga
tttccccaggaggagtttgatggcaaccagttccagaaggctccagccatctctgtcctc
catgagctgatccagcagatcttcaacctctttaccacaaaagattcatctgctgcttgg
gatgaggaactcctagacaaattctgcactgaactctaccagcagctgaatgacttggaa
gcctgtgtgatgcaggaggagagggtgggagaaactcccctgatgaatgcggactccatc
ttggctgtgaagaaatacttccgaagaatcactctctatctgacagagaagaaatacagc
ccttgtgcctgggaggttgtcagagcagaaatcatgagatccctctctttatcaacaaac
ttgcaagaaagattaaggaggaaggaataa

KEGG   Pan paniscus (bonobo): 100973400
Entry
100973400         CDS       T02283                                 

Gene name
IFNE
Definition
(RefSeq) interferon epsilon
  KO
K05442  interferon epsilon
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04622  RIG-I-like receptor signaling pathway
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100973400 (IFNE)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100973400 (IFNE)
 09150 Organismal Systems
  09151 Immune system
   04622 RIG-I-like receptor signaling pathway
    100973400 (IFNE)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100973400 (IFNE)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100973400 (IFNE)
SSDB
Motif
Pfam: Interferon DUF1027
Other DBs
NCBI-GeneID: 100973400
NCBI-ProteinID: XP_003830727
UniProt: A0A2R8ZBR9
Position
9
AA seq 208 aa
MIIKHFFGIVLVLLASTTIFSLDLKLIIFQQRQVNQESLKLLNKLQTLSIQQCLPHRKNF
LLPQKSLSLQQYQKGHTLAILHEMLQQIFSLFRANISLDGWEENHMEKFLIQLHQQLEYL
EALMGLEAEKLSGTLGSDNLRLQVKMYFRRIHDYLENQDDSTCAWAIVQVEISRCLFFVF
SLTEKLSKQGRPLNDMKQELTTEFRSPR
NT seq 627 nt   +upstreamnt  +downstreamnt
atgattatcaagcacttctttggaattgtgttggtgctgctggcctctaccactatcttc
tctctagatttgaaactgattatcttccagcaaagacaagtgaatcaagaaagtttaaaa
ctcttgaataagttgcaaaccttgtcaattcagcagtgtctaccacacaggaaaaacttt
ctgcttcctcagaagtctttgagtcttcagcagtaccaaaaaggacacactctggccatt
ctccatgagatgcttcagcagatcttcagcctcttcagggcaaatatttctctggatggt
tgggaggaaaaccacatggagaaattcctcattcaacttcatcaacagctagaataccta
gaagcactcatgggactggaagcagagaagctaagtggtactttgggtagtgataacctt
agattacaagttaaaatgtacttccgaaggatccatgattacctggaaaaccaggacgac
agcacctgtgcctgggccattgtccaagtagaaatcagccgatgtctgttctttgtgttc
agtctcacagaaaaactgagcaaacaaggaagacccttgaacgacatgaagcaagagctt
actacagagtttagaagcccaaggtag

KEGG   Pan paniscus (bonobo): 100974265
Entry
100974265         CDS       T02283                                 

Gene name
IL23A
Definition
(RefSeq) interleukin 23 subunit alpha
  KO
K05426  interleukin 23 subunit alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04625  C-type lectin receptor signaling pathway
pps04630  JAK-STAT signaling pathway
pps04659  Th17 cell differentiation
pps05133  Pertussis
pps05152  Tuberculosis
pps05200  Pathways in cancer
pps05321  Inflammatory bowel disease
pps05323  Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100974265 (IL23A)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100974265 (IL23A)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100974265 (IL23A)
   04659 Th17 cell differentiation
    100974265 (IL23A)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100974265 (IL23A)
  09171 Infectious disease: bacterial
   05133 Pertussis
    100974265 (IL23A)
   05152 Tuberculosis
    100974265 (IL23A)
  09163 Immune disease
   05323 Rheumatoid arthritis
    100974265 (IL23A)
   05321 Inflammatory bowel disease
    100974265 (IL23A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100974265 (IL23A)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100974265 (IL23A)
SSDB
Motif
Pfam: IL23 IL6
Other DBs
NCBI-GeneID: 100974265
NCBI-ProteinID: XP_003824971
UniProt: A0A2R9CIV0
Position
12
AA seq 189 aa
MLGSRAVMLLLLLPWTAQGRAVPGGSSPAWTQCQQLSQKLCTLAWSAHPLVGHMDLREEG
DEETTNDVPHIQCGDGCDPQGLRDNSQFCLQRIHQGLIFYEKLLGSDIFTGEPSLLPDSP
VGQLHASLLGLSQLLQPEGHHWETQQIPSLSPSQPWQRLLLRFKILRSLQAFVAVAARVF
AHGAATLSP
NT seq 570 nt   +upstreamnt  +downstreamnt
atgctggggagcagagctgtaatgctgctattgctgctgccctggacagctcagggcaga
gctgtgcctgggggcagcagccctgcctggactcagtgccagcagctttcacagaagctc
tgcacactggcctggagtgcacatccactagtgggacacatggatctaagagaagaggga
gatgaagagactacaaatgatgttccccatatccagtgtggagatggctgtgacccccaa
ggactcagggacaacagtcagttctgcttgcaaaggatccaccagggtctgattttttat
gagaagctgctaggatcggatattttcacaggggagccttctctgctccctgatagccct
gtgggccagcttcatgcctccctactgggcctcagccaactcctgcagcctgagggtcac
cactgggagactcagcagattccaagcctcagtcccagccagccatggcagcgtctcctt
ctccgcttcaaaatccttcgcagcctccaggcctttgtggctgtagccgcccgggtcttt
gcccatggagcagcaaccctgagtccctaa

KEGG   Pan paniscus (bonobo): 100974554
Entry
100974554         CDS       T02283                                 

Gene name
IL17D
Definition
(RefSeq) interleukin 17D
  KO
K05492  interleukin 17D
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04625  C-type lectin receptor signaling pathway
pps04630  JAK-STAT signaling pathway
pps04657  IL-17 signaling pathway
pps04659  Th17 cell differentiation
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100974554 (IL17D)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100974554 (IL17D)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100974554 (IL17D)
   04659 Th17 cell differentiation
    100974554 (IL17D)
   04657 IL-17 signaling pathway
    100974554 (IL17D)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100974554 (IL17D)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100974554 (IL17D)
SSDB
Motif
Pfam: IL17
Other DBs
NCBI-GeneID: 100974554
NCBI-ProteinID: XP_008956755
Position
13
AA seq 202 aa
MLVAGFLLALPPSWAAGXPRAGRRPARPRGCADRPEELLEQLYGRLAAGVLSAFHHTLQL
GPREQARNASCPAGGRPADRRFRPPTNLRSVSPWAYRISYDPARYPRYLPEAYCLCRGCL
TGLFGEEDVRFRSAPVYMPTVVLRRTPACAGGRSVYTEAYVTIPVGCTCVPEPEKDADSI
NSSIDKQGAKLLLGPNDAPAGP
NT seq 609 nt   +upstreamnt  +downstreamnt
atgctggtagccggcttcctgctggcgctgccgccgagctgggccgcgggcngcccgagg
gcgggcaggcgcccggcgcggccgcggggctgcgcggaccggccagaggagctactggag
cagctgtacgggcgcctggcggccggcgtgctcagcgccttccaccacacgctgcagctg
gggccgcgtgagcaggcgcgcaacgcgagctgcccggcagggggcaggcccgccgaccgc
cgcttccggccgcccaccaacctgcgcagcgtgtcgccctgggcctacagaatctcctac
gacccggcgaggtaccccaggtacctgcctgaagcctactgcctgtgccggggctgcctg
accgggctgttcggcgaggaggacgtgcgcttccgcagcgcccctgtctacatgcccacc
gtcgtcctgcgccgcacccccgcctgcgccggcggccgttccgtctacaccgaggcctac
gtcaccatccccgtgggctgcacctgcgtccccgagccggagaaggacgcagacagcatc
aactccagcatcgacaaacagggcgccaagctcctgctgggccccaacgacgcgcccgct
ggcccctga

KEGG   Pan paniscus (bonobo): 100975561
Entry
100975561         CDS       T02283                                 

Definition
(RefSeq) interferon lambda-3-like
  KO
K22669  interferon lambda 2/3
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100975561
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100975561
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100975561
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100975561
SSDB
Motif
Pfam: IL28A
Other DBs
NCBI-GeneID: 100975561
NCBI-ProteinID: XP_003804216
Position
Un
AA seq 125 aa
EELLLLKDCRCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLEATADTDPALGDVLD
QPLHTLHHILSQLRACIQPQPTAGPRTQGRLHHWLHRLQEAPKKESPGCLEASVTFNLFR
LLTRA
NT seq 378 nt   +upstreamnt  +downstreamnt
gaagagttgcttctgctgaaggactgcaggtgccgctcccgcctcttccccaggacctgg
gacctgaggcagctgcaggtgagggagcgccccgtggctttggaggctgagctggccctg
acgctgaaggttctggaggccaccgctgacactgacccagccctgggggatgtcttggac
cagccccttcacaccctgcaccatatcctctcccagctccgggcctgtatccagcctcag
cccacggcagggcccaggacccagggccgcctccaccattggctgcaccggctccaggag
gccccaaaaaaggagtcccctggctgcctcgaggcctctgtcaccttcaacctcttccgc
ctcctcacgcgagcctga

KEGG   Pan paniscus (bonobo): 100976419
Entry
100976419         CDS       T02283                                 

Gene name
IFNL1, IL29
Definition
(RefSeq) interferon lambda 1
  KO
K05447  interferon lambda 1
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100976419 (IFNL1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100976419 (IFNL1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100976419 (IFNL1)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100976419 (IFNL1)
SSDB
Motif
Pfam: IL28A
Other DBs
NCBI-GeneID: 100976419
NCBI-ProteinID: XP_003812294
UniProt: A0A2R8ZPR7
Position
19
AA seq 200 aa
MAAAWTVVLVTLVLGLAVAGPVPTSKPTTTGKGCHIGRFKSLSPQELASFKKARDALEES
LKLKNWSCSSPVFPGNWDLRLLQVRERPVALEAELALTLKVLEAAAGPALEDVLDQPLHT
LHHILSQLQACIQPQPTAGPRPRGRLHHWLHRLQEAPKKESPGCLEASVTFNLFRLLTRD
LKCVADGDLCLRTSTHPEST
NT seq 603 nt   +upstreamnt  +downstreamnt
atggctgcagcttggaccgtggtgctggtgactttggtgctaggcttggccgtggcaggc
cctgtccccacttccaagcccaccacaactgggaagggctgccacattggcaggttcaaa
tctctgtcaccacaggagctagcgagcttcaagaaggccagggacgccttggaagagtca
ctcaagctgaaaaactggagttgcagctctcctgtcttccccgggaactgggacctgagg
cttctccaggtgagggagcgccctgtggccttggaggctgagctggccctgacgctgaag
gtcctggaggccgctgctggcccagccctggaggacgtcctagaccagccccttcacacc
ctgcaccacatcctctcccagctccaggcctgtatccagcctcagcccacggcagggccc
aggccccggggccgcctccaccactggctgcaccggctccaggaggcccccaaaaaggag
tctcctggctgcctggaggcgtctgtcaccttcaacctcttccgcctcctcacgcgagac
ctcaaatgtgtggccgatggggacctgtgtctgagaacgtcaacccaccccgagtccacc
tga

KEGG   Pan paniscus (bonobo): 100976754
Entry
100976754         CDS       T02283                                 

Gene name
IL28A
Definition
(RefSeq) interferon lambda-3
  KO
K22669  interferon lambda 2/3
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100976754 (IL28A)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100976754 (IL28A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100976754 (IL28A)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100976754 (IL28A)
SSDB
Motif
Pfam: IL28A
Other DBs
NCBI-GeneID: 100976754
NCBI-ProteinID: XP_008962897
UniProt: A0A2R9C0I3
Position
19
AA seq 196 aa
MTGGCTPVLVLMATVLTVTAAVPVARLRGALPDARGCHIAQFKSLSPQELQAFKRAKDAL
EELLLLKDCRCRSRLFPRTWDLRQLQVRERPMALEAELALTLKVLEAAADTDPALVDVLD
QPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTFNLFR
LLTRDLNCVASGDLCV
NT seq 591 nt   +upstreamnt  +downstreamnt
atgaccgggggctgcacgccagtgctggtgctgatggccacagtgctgaccgtgactgca
gcagttcctgtcgccaggctccgcggggctctcccggatgcaaggggctgccacatagcc
cagttcaagtccctgtctccacaggagctgcaggcctttaagagggccaaagatgcctta
gaagagttgcttctgctgaaggactgcaggtgccgctcccgcctcttccccaggacctgg
gacctgaggcagctgcaggtgagggagcgccccatggctttggaggctgagctggccctg
acgctgaaggttctggaggccgccgctgacactgacccagccctggtggacgtcttggac
cagccccttcacaccctgcaccatatcctctcccagctccgggcctgtatccagcctcag
cccacggcagggcccaggacccggggccgcctccaccattggctgcaccggctccaggag
gccccaaaaaaggagtcccctggctgcctcgaggcctctgtcaccttcaaccttttccgc
ctcctcacacgagacctgaattgtgtcgccagcggggacctgtgtgtctga

KEGG   Pan paniscus (bonobo): 100979574
Entry
100979574         CDS       T02283                                 

Gene name
IL12A
Definition
(RefSeq) interleukin 12A
  KO
K05406  interleukin 12A
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04620  Toll-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04625  C-type lectin receptor signaling pathway
pps04630  JAK-STAT signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps04940  Type I diabetes mellitus
pps05133  Pertussis
pps05134  Legionellosis
pps05140  Leishmaniasis
pps05142  Chagas disease
pps05143  African trypanosomiasis
pps05144  Malaria
pps05145  Toxoplasmosis
pps05146  Amoebiasis
pps05152  Tuberculosis
pps05162  Measles
pps05164  Influenza A
pps05168  Herpes simplex virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05321  Inflammatory bowel disease
pps05330  Allograft rejection
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100979574 (IL12A)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100979574 (IL12A)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100979574 (IL12A)
   04622 RIG-I-like receptor signaling pathway
    100979574 (IL12A)
   04625 C-type lectin receptor signaling pathway
    100979574 (IL12A)
   04658 Th1 and Th2 cell differentiation
    100979574 (IL12A)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100979574 (IL12A)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    100979574 (IL12A)
   05164 Influenza A
    100979574 (IL12A)
   05162 Measles
    100979574 (IL12A)
   05168 Herpes simplex virus 1 infection
    100979574 (IL12A)
  09171 Infectious disease: bacterial
   05133 Pertussis
    100979574 (IL12A)
   05134 Legionellosis
    100979574 (IL12A)
   05152 Tuberculosis
    100979574 (IL12A)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100979574 (IL12A)
   05144 Malaria
    100979574 (IL12A)
   05145 Toxoplasmosis
    100979574 (IL12A)
   05140 Leishmaniasis
    100979574 (IL12A)
   05142 Chagas disease
    100979574 (IL12A)
   05143 African trypanosomiasis
    100979574 (IL12A)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100979574 (IL12A)
   05330 Allograft rejection
    100979574 (IL12A)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100979574 (IL12A)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    100979574 (IL12A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100979574 (IL12A)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100979574 (IL12A)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100979574 (IL12A)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Cytokines
   100979574 (IL12A)
SSDB
Motif
Pfam: IL12 Rh5
Other DBs
NCBI-GeneID: 100979574
NCBI-ProteinID: XP_003830676
UniProt: A0A2R9BQY2
Position
3
AA seq 253 aa
MWPPGSASQPPPSPAAATGLHPAARPVSLQCRLSMCPARSLLLVATLVLLDHLSLARNLP
VATPDPGMFPCLHHSQNLLRAVSNMLQKARQTLEFYPCTSEEIDHEDITKDKTSTVEACL
PLELTKNESCLNSRETSFITNGSCLASRKTSFMMALCLSSIYEDLKMYQVEFKTMNAKLL
MDPKRQIFLDQNMLAVIDELMQALNFNSETVPQKSSLEELDFYKTKIKLCILLHAFRIRA
VTIDRVMSYLNAS
NT seq 762 nt   +upstreamnt  +downstreamnt
atgtggccccctgggtcagcctcccagccaccgccctcacctgccgcggccacaggtctg
catccagcggctcgcccagtgtccctgcagtgccggctcagcatgtgtccagcgcgcagc
ctcctccttgtggctaccctggtcctcctggaccacctcagtttggccagaaacctcccc
gtggccaccccagacccaggaatgttcccatgccttcaccactcccaaaacctgctgagg
gccgtcagcaacatgctccagaaggccagacaaactctagaattttacccttgcacttct
gaagagattgatcatgaagatatcacaaaagataaaaccagcacagtggaggcctgttta
ccattggaattaaccaagaatgagagttgcctaaattccagagagacctctttcataact
aatgggagttgcctggcctccagaaagacctcttttatgatggccctgtgccttagtagt
atttatgaagacttgaagatgtaccaggtggagttcaagaccatgaatgcaaagcttctg
atggatcctaagaggcagatctttctagatcaaaacatgctggcagttattgacgagctg
atgcaggccctgaatttcaacagtgagactgtgccacaaaaatcctcccttgaagaactg
gatttttataaaactaaaatcaagctctgcatacttcttcatgctttcagaattcgggca
gtgactattgatagagtgatgagctatctgaatgcttcctaa

KEGG   Pan paniscus (bonobo): 100982287
Entry
100982287         CDS       T02283                                 

Gene name
IFNK
Definition
(RefSeq) interferon kappa
  KO
K05441  interferon kappa
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04622  RIG-I-like receptor signaling pathway
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100982287 (IFNK)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100982287 (IFNK)
 09150 Organismal Systems
  09151 Immune system
   04622 RIG-I-like receptor signaling pathway
    100982287 (IFNK)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100982287 (IFNK)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100982287 (IFNK)
SSDB
Motif
Pfam: Interferon
Other DBs
NCBI-GeneID: 100982287
NCBI-ProteinID: XP_008954361
Position
9
AA seq 207 aa
MSTKPDMIQKCLWLEILMGIFVAGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPVECL
XENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFSQHTFKYWKERHLKQIQIGLDQ
QAEYLNQCLEEDENENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKKYSD
CAWEIVRVEIRRCLYYFYKFTALFRRK
NT seq 624 nt   +upstreamnt  +downstreamnt
atgagcaccaaacctgatatgattcaaaagtgtttgtggcttgagatccttatgggtata
ttcgttgctggcaccctatccctggactgtaacttactgaacgttcacctgagaagagtc
acctggcaaaatctgagacatctgagtagtatgagcaattcatttcctgtagaatgttta
tgagaaaacatagcttttgagttgccccaagagtttctgcaatacacccaacctatgaag
agggacatcaagaaggccttctatgaaatgtccctgcaggccttcaacatcttcagccaa
cacaccttcaaatattggaaagagagacacctcaaacaaatccaaataggacttgatcag
caagcagagtacctgaaccaatgcttggaggaagatgagaatgaaaatgaagacatgaaa
gaaatgaaagagaatgagatgaaaccctcagaagccagggtcccccagctgagcagcctg
gaactgaggagatatttccacaggatagacaatttcctgaaagaaaagaaatacagtgac
tgtgcctgggagattgtccgagtggaaatcagaagatgtttgtactacttttacaaattt
acagctctattcaggaggaaataa

KEGG   Pan paniscus (bonobo): 100982675
Entry
100982675         CDS       T02283                                 

Gene name
IL11
Definition
(RefSeq) interleukin 11
  KO
K05417  interleukin 11
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps05323  Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100982675 (IL11)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100982675 (IL11)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100982675 (IL11)
 09160 Human Diseases
  09163 Immune disease
   05323 Rheumatoid arthritis
    100982675 (IL11)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100982675 (IL11)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100982675 (IL11)
SSDB
Motif
Pfam: IL11
Other DBs
NCBI-GeneID: 100982675
NCBI-ProteinID: XP_003807149
UniProt: A0A2R9BY61
Position
19
AA seq 199 aa
MNCVCRLVLVVLSLWPDTAVAPGPPPGPPRVSPDPRAELDSTVLLTRSLLADTRQLAAQL
RDKFPADGDHNLDSLPTLAMSAGALGALQLPGVLTRLRADLLSYLRHVQWLRRAGGSSLK
TLEPELGTLQARLDRLLRRLQLLMSRLALPQPPPDPPAPPLAPPSSAWGGIRAAHAILGG
LHLTLDWAVRGLLLLKTRL
NT seq 600 nt   +upstreamnt  +downstreamnt
atgaactgtgtttgccgcctggtcctggtcgtgctgagcctgtggccagatacagctgtc
gcccctgggccaccacctggcccccctcgagtttccccagaccctcgggccgagctggac
agcaccgtgctcctgacccgctccctcctggcggacacgcggcagctggctgcacagctg
agggacaaattcccagctgacggggaccacaacctggattccctgcccaccctggccatg
agtgcgggggcactgggagctctacagctcccgggtgtgctgacaaggctgcgagcggac
ctactgtcctacctgcggcacgtgcagtggctgcgccgggcaggtggctcttccctgaag
accctggagcccgagctgggcaccctgcaggcccggctggaccggctgctgcgccggctg
cagctcctgatgtcccgcctggccctgccccagccacccccggacccgccggcgcccccg
ctggcgcccccctcctcagcctggggaggcatcagggccgcccacgccatcctggggggg
ctacacctgacacttgactgggccgtgaggggactgctgctgctgaagactcggctgtga

KEGG   Pan paniscus (bonobo): 100984436
Entry
100984436         CDS       T02283                                 

Gene name
IL21
Definition
(RefSeq) interleukin 21
  KO
K05434  interleukin 21
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04659  Th17 cell differentiation
pps05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100984436 (IL21)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100984436 (IL21)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100984436 (IL21)
 09160 Human Diseases
  09163 Immune disease
   05321 Inflammatory bowel disease
    100984436 (IL21)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100984436 (IL21)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100984436 (IL21)
SSDB
Motif
Pfam: IL15
Other DBs
NCBI-GeneID: 100984436
NCBI-ProteinID: XP_003816452
UniProt: A0A2R9BR35
Position
4
AA seq 162 aa
MRSSPGNMERIVICLMVIFLGTLVHKSSSQGQDRHMIRMRQLIDIVDQLKNYVNDLVPEF
LPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRL
TCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS
NT seq 489 nt   +upstreamnt  +downstreamnt
atgagatccagtcctggcaacatggagaggattgtcatctgtctgatggtcatcttcttg
gggacactggtccacaaatcaagctctcaaggtcaagatcgccacatgattagaatgcgt
caacttatagatattgttgatcagctgaaaaattatgtgaatgacttggtccctgaattt
ctgccagctccagaagatgtagagacaaactgtgagtggtcagctttttcctgttttcag
aaggcccaactaaagtcagcaaatacaggaaacaatgaaaggataatcaatgtatcaatt
aaaaagctgaagaggaaaccaccttccacaaatgcagggagaagacagaaacacagacta
acatgcccttcatgtgattcttatgagaaaaaaccacccaaagaattcctagaaagattc
aaatcacttctccaaaagatgattcatcagcatctgtcctctagaacacacggaagtgaa
gattcctga

KEGG   Pan paniscus (bonobo): 100984780
Entry
100984780         CDS       T02283                                 

Gene name
IL2
Definition
(RefSeq) interleukin 2
  KO
K05429  interleukin 2
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04151  PI3K-Akt signaling pathway
pps04625  C-type lectin receptor signaling pathway
pps04630  JAK-STAT signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps04660  T cell receptor signaling pathway
pps04672  Intestinal immune network for IgA production
pps04940  Type I diabetes mellitus
pps05135  Yersinia infection
pps05142  Chagas disease
pps05162  Measles
pps05166  Human T-cell leukemia virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05320  Autoimmune thyroid disease
pps05321  Inflammatory bowel disease
pps05330  Allograft rejection
pps05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100984780 (IL2)
   04151 PI3K-Akt signaling pathway
    100984780 (IL2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100984780 (IL2)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100984780 (IL2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100984780 (IL2)
   04660 T cell receptor signaling pathway
    100984780 (IL2)
   04658 Th1 and Th2 cell differentiation
    100984780 (IL2)
   04659 Th17 cell differentiation
    100984780 (IL2)
   04672 Intestinal immune network for IgA production
    100984780 (IL2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100984780 (IL2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100984780 (IL2)
   05171 Coronavirus disease - COVID-19
    100984780 (IL2)
   05162 Measles
    100984780 (IL2)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100984780 (IL2)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    100984780 (IL2)
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100984780 (IL2)
   05321 Inflammatory bowel disease
    100984780 (IL2)
   05330 Allograft rejection
    100984780 (IL2)
   05332 Graft-versus-host disease
    100984780 (IL2)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    100984780 (IL2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100984780 (IL2)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100984780 (IL2)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100984780 (IL2)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Cytokines
   100984780 (IL2)
SSDB
Motif
Pfam: IL2 Plasmid_RAQPRD
Other DBs
NCBI-GeneID: 100984780
NCBI-ProteinID: XP_003816453
UniProt: A0A2R9ACE1
Position
4
AA seq 153 aa
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRML
TFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSE
TTFMCEYADETATIVEFLNRWITFCQSIISTLT
NT seq 462 nt   +upstreamnt  +downstreamnt
atgtacaggatgcaactcctgtcttgcattgcactaagtcttgcacttgtcacaaacagt
gcacctacttcaagttctacaaagaaaacacagctacaactggagcatttactgctggat
ttacagatgattttgaatggaattaataattacaagaatcccaaactcaccaggatgctc
acatttaagttttacatgcccaagaaggccacagaactgaaacatcttcagtgtctagaa
gaagaactcaaacctctggaggaagtgctaaatttagctcaaagcaaaaactttcactta
agacccagggacttaatcagcaatatcaacgtaatagttctggaactaaagggatctgaa
acaacattcatgtgtgaatatgctgatgagacagcaaccattgtagaatttctgaacaga
tggattaccttttgtcaaagcatcatctcaacactgacttga

KEGG   Pan paniscus (bonobo): 100986540
Entry
100986540         CDS       T02283                                 

Gene name
IL7
Definition
(RefSeq) interleukin 7
  KO
K05431  interleukin 7
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100986540 (IL7)
   04151 PI3K-Akt signaling pathway
    100986540 (IL7)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100986540 (IL7)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100986540 (IL7)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100986540 (IL7)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100986540 (IL7)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100986540 (IL7)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100986540 (IL7)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Cytokines
   100986540 (IL7)
SSDB
Motif
Pfam: IL7
Other DBs
NCBI-GeneID: 100986540
NCBI-ProteinID: XP_003831335
Position
8
AA seq 177 aa
MFHVSFRYIFGLPPLILVLLPVASSDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCL
NNEFNFFKRHICDANKEGMFLFRAARKLRQFLKMNSTGDFDLHLLKVSEGTTILLNCTGQ
VKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEH
NT seq 534 nt   +upstreamnt  +downstreamnt
atgttccatgtttcttttaggtatatctttggacttcctcccctgatccttgttctgttg
ccagtagcatcatctgattgtgatattgaaggtaaagatggcaaacaatatgagagtgtt
ctaatggtcagcatcgatcaattattggacagcatgaaagaaattggtagcaattgcctg
aataatgaatttaacttttttaaaagacatatctgtgatgctaataaggaaggtatgttt
ttattccgtgctgctcgcaagttgaggcaatttcttaaaatgaatagcactggtgatttt
gatctccacttattaaaagtttcagaaggcacaacaatactgttgaactgcactggccag
gttaaaggaagaaaaccagctgccctgggtgaagcccaaccaacaaagagtttggaagaa
aataaatctttaaaggaacagaaaaaactgaatgacttgtgtttcctaaagagactacta
caagagataaaaacttgttggaataaaattttgatgggcactaaagaacactga

KEGG   Pan paniscus (bonobo): 100986810
Entry
100986810         CDS       T02283                                 

Definition
(RefSeq) cardiotrophin-2
  KO
K24382  cardiotrophin 2
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100986810
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100986810
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100986810
Cytokines and growth factors [BR:pps04052]
 Cytokines
  CSF and other factors
   100986810
SSDB
Motif
Pfam: PRF CNTF LIF_OSM
Other DBs
NCBI-GeneID: 100986810
NCBI-ProteinID: XP_003807534
Position
16
AA seq 203 aa
MSCSLAGLCLLTLLSPPLSSAASISPAEPISQAYSLALYMQKNTSALLRTYLQYQGSPFS
DPGFSAPELQLSSLPPATAFFKTWHALDDGEWLSLAQRAFLALTQHLQLVEDDQSDLNPG
SPILLAQLRAARLRAQGLLGNMAAIMTALGLPIPPEEDTLGLAAFGASAFERKCRGYVVT
REYGHWTDRAVRDLALLKAKYSA
NT seq 612 nt   +upstreamnt  +downstreamnt
atgagctgttcactggccggcctctgcctgctgaccctgctgtcgccacccctcagctca
gcagcctccatctccccagctgagcccatcagtcaagcctatagcctggccctctacatg
cagaagaacacctcagcgctgctgcggacttacctccagtaccagggcagcccctttagt
gaccctggcttctcagcccctgagctccagctcagcagcctgcctcctgccaccgccttc
tttaagacctggcacgccctggatgacggggaatggctgagccttgcccagagggccttc
ctggcattgacccagcacctccagctcgtggaagacgaccagagcgacctgaaccctggc
agtcccatcctgctggctcagctcagggctgcgagactcagggcccaaggcctgctgggc
aatatggccgccatcatgacggccctggggctgccaatccccccagaagaggatactcta
gggcttgctgcctttggggcctcggcctttgagaggaaatgtcgaggctacgtggtgacc
cgggaatatggccactggacagaccgagctgtgagagacttggctctgctcaaggctaag
tactcagcatag

KEGG   Pan paniscus (bonobo): 100988257
Entry
100988257         CDS       T02283                                 

Gene name
IL15
Definition
(RefSeq) interleukin 15
  KO
K05433  interleukin 15
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04668  TNF signaling pathway
pps04672  Intestinal immune network for IgA production
pps05166  Human T-cell leukemia virus 1 infection
pps05200  Pathways in cancer
pps05323  Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100988257 (IL15)
   04668 TNF signaling pathway
    100988257 (IL15)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100988257 (IL15)
 09150 Organismal Systems
  09151 Immune system
   04672 Intestinal immune network for IgA production
    100988257 (IL15)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100988257 (IL15)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100988257 (IL15)
  09163 Immune disease
   05323 Rheumatoid arthritis
    100988257 (IL15)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100988257 (IL15)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100988257 (IL15)
SSDB
Motif
Pfam: IL15
Other DBs
NCBI-GeneID: 100988257
NCBI-ProteinID: XP_003820741
UniProt: A0A2R9CIQ0
Position
4
AA seq 162 aa
MRISKPHLRSISIQCYLCLLLNSHFLTEAGIHVFILGCFSAGLPKTEANWVNVISDLKKI
EDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANN
SLSSNGNVTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS
NT seq 489 nt   +upstreamnt  +downstreamnt
atgagaatttcgaaaccacatttgagaagtatttccatccagtgctacttgtgtttactt
ctaaacagtcattttctaactgaagctggcattcatgtcttcattttgggctgtttcagt
gcagggcttcctaaaacagaagccaactgggtgaatgtaataagtgatttgaaaaaaatt
gaagatcttattcaatctatgcatattgatgctactttatatacggaaagtgatgttcac
cccagttgcaaagtaacagcaatgaagtgctttctcttggagttacaagttatttcactt
gagtccggagatgcaagtattcatgatacagtagaaaatctgatcatcctagcaaacaac
agtttgtcttctaatgggaatgtaacagaatctggatgcaaagaatgtgaggaactggag
gaaaaaaatattaaagaatttttgcagagttttgtacatattgtccaaatgttcatcaac
acttcttga

KEGG   Pan paniscus (bonobo): 100988832
Entry
100988832         CDS       T02283                                 

Gene name
IL24
Definition
(RefSeq) interleukin 24
  KO
K22668  interleukin 24
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100988832 (IL24)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100988832 (IL24)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100988832 (IL24)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100988832 (IL24)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100988832 (IL24)
SSDB
Motif
Pfam: IL22 IL10
Other DBs
NCBI-GeneID: 100988832
NCBI-ProteinID: XP_003822961
Position
1
AA seq 207 aa
MNFQQRLQSLWTLASRPFCPPLLATASQMQMAVLPCLGFTLLLWSQVSGAQGQEFQFGPC
QVKGVVPQKLWEAFWAVKDTTQAQDNITSARLLQQEVLQNVSDAESCYLVHTLLEFYLKT
VFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEMFSIRDSAHRRFLLFRRAFKQ
LDVEAALTKALGEVDILLTWMQKFYKL
NT seq 624 nt   +upstreamnt  +downstreamnt
atgaattttcaacagaggctgcaaagcctgtggactttagccagcagacccttctgccct
cctttgctggcgacagcctctcaaatgcagatggctgtgctcccttgcctgggttttacc
ctgcttctctggagccaggtatcaggggcccagggccaagaattccaatttgggccctgc
caagtgaagggggttgttccccagaaactgtgggaagccttctgggctgtgaaagacact
acgcaagctcaggataacatcacgagtgcccggctgctgcagcaggaggttctgcagaac
gtctcggatgctgagagctgttaccttgtccacaccctgctggagttctacttgaaaact
gttttcaaaaactaccacaatagaacagttgaagtcaggactctgaagtcattctctact
ctggccaacaactttgttctcatcgtgtcacaactgcaacccagtcaagaaaatgagatg
ttttccatcagagacagtgcacacaggcggtttctgctattccggagagcattcaaacag
ttggacgtagaagcagctctgaccaaagcccttggggaagtggacattcttctgacctgg
atgcagaaattctacaagctctga

KEGG   Pan paniscus (bonobo): 100988878
Entry
100988878         CDS       T02283                                 

Gene name
IL4
Definition
(RefSeq) interleukin 4
  KO
K05430  interleukin 4
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps04657  IL-17 signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps04660  T cell receptor signaling pathway
pps04664  Fc epsilon RI signaling pathway
pps04672  Intestinal immune network for IgA production
pps05140  Leishmaniasis
pps05200  Pathways in cancer
pps05310  Asthma
pps05320  Autoimmune thyroid disease
pps05321  Inflammatory bowel disease
pps05330  Allograft rejection
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100988878 (IL4)
   04151 PI3K-Akt signaling pathway
    100988878 (IL4)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100988878 (IL4)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100988878 (IL4)
   04660 T cell receptor signaling pathway
    100988878 (IL4)
   04658 Th1 and Th2 cell differentiation
    100988878 (IL4)
   04659 Th17 cell differentiation
    100988878 (IL4)
   04657 IL-17 signaling pathway
    100988878 (IL4)
   04664 Fc epsilon RI signaling pathway
    100988878 (IL4)
   04672 Intestinal immune network for IgA production
    100988878 (IL4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100988878 (IL4)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    100988878 (IL4)
  09163 Immune disease
   05310 Asthma
    100988878 (IL4)
   05320 Autoimmune thyroid disease
    100988878 (IL4)
   05321 Inflammatory bowel disease
    100988878 (IL4)
   05330 Allograft rejection
    100988878 (IL4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100988878 (IL4)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100988878 (IL4)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100988878 (IL4)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Cytokines
   100988878 (IL4)
SSDB
Motif
Pfam: IL4 Mannosyl_trans3
Other DBs
NCBI-GeneID: 100988878
NCBI-ProteinID: XP_003829346
UniProt: A0A2R8ZXQ5
Position
5
AA seq 153 aa
MGLTSQLLPPLFFLLACAGNFVHGHKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAAS
KNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGL
NSCPVKEANQSTLEDFLERLKTIMREKYSKCSS
NT seq 462 nt   +upstreamnt  +downstreamnt
atgggtctcacctcccaactgcttccccctctgttcttcctgctagcatgtgccggcaac
tttgtccacggacacaagtgcgatatcaccttacaggagatcatcaaaactttgaacagc
ctcacagagcagaagactctgtgcaccgagttgaccgtaacggacatctttgctgcctcc
aagaacacaactgagaaggaaaccttctgcagggctgcgactgtgctccggcagttctac
agccaccatgagaaggacactcgctgcctgggtgcgactgcacagcagttccacaggcac
aagcagctgatccgattcctgaaacggctcgacaggaacctctggggcctggcgggcttg
aattcctgtcctgtgaaggaagccaaccagagtacgttggaagacttcttggaaaggcta
aagacgatcatgagagagaaatattcaaagtgttcgagctga

KEGG   Pan paniscus (bonobo): 100989787
Entry
100989787         CDS       T02283                                 

Gene name
IL13
Definition
(RefSeq) interleukin 13
  KO
K05435  interleukin 13
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04657  IL-17 signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps04664  Fc epsilon RI signaling pathway
pps05200  Pathways in cancer
pps05310  Asthma
pps05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100989787 (IL13)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100989787 (IL13)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    100989787 (IL13)
   04657 IL-17 signaling pathway
    100989787 (IL13)
   04664 Fc epsilon RI signaling pathway
    100989787 (IL13)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100989787 (IL13)
  09163 Immune disease
   05310 Asthma
    100989787 (IL13)
   05321 Inflammatory bowel disease
    100989787 (IL13)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100989787 (IL13)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100989787 (IL13)
SSDB
Motif
Pfam: IL13
Other DBs
NCBI-GeneID: 100989787
NCBI-ProteinID: XP_003829348
UniProt: A0A2R9AD95
Position
5
AA seq 146 aa
MRPLLNPLLLALGLMALLLTTVIALTCLGGFASPGPVPPSTALRELIEELVNITQNQKAP
LCNGSMVWSINLTAGVYCAALESLINVSGCSAIEKTQRMLSGFCPHKVSAGQFSSLHVRD
TKIEVAQFVKDLLLHLKKLFREGRFN
NT seq 441 nt   +upstreamnt  +downstreamnt
atgcgtccgctcctcaatcctctcctgttggcactgggcctcatggcgcttttgttgacc
acggtcattgctctcacttgccttggcggctttgcctccccaggccctgtgcctccctct
acagccctcagggagctcattgaggagctggtcaacatcacccagaaccagaaggctccg
ctctgcaatggcagcatggtatggagcatcaacctgacagctggcgtgtactgtgcagcc
ctggaatccctgatcaacgtgtcaggctgcagtgccatcgagaagacccagaggatgctg
agcggattctgcccgcacaaggtctcagctgggcagttttccagcttgcatgtccgagac
accaaaatcgaggtggcccagtttgtaaaggacctgctcttacatttaaagaaacttttt
cgcgagggacggttcaactga

KEGG   Pan paniscus (bonobo): 100989863
Entry
100989863         CDS       T02283                                 

Gene name
IL20
Definition
(RefSeq) interleukin 20
  KO
K22667  interleukin 20
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100989863 (IL20)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100989863 (IL20)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100989863 (IL20)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100989863 (IL20)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100989863 (IL20)
SSDB
Motif
Pfam: IL10
Other DBs
NCBI-GeneID: 100989863
NCBI-ProteinID: XP_003822963
Position
1
AA seq 261 aa
MRQFPKTSFDISPEMSFSIYSLQVPAVPGLTCWALTAEPGWGQNKGATTCGTNSHSDSEL
RPEIFSSWEARQFFLLLWSPDFRPKMKASSLAFSLLSAAFYLLWTPSTGLKTLNLGSCVI
ATNLQEIRNGFSEIRGSVQAKDGNIDIRILRRTESLQDTKPANRCCLLRHLLRLYLDRVF
KNYQTPDHYTLRKISSLANSFLTIKKDLRLCHAHMTCHCGEEAMKKYSQILSHFEKLEPQ
AAVVKALGELDILLQWMEETE
NT seq 786 nt   +upstreamnt  +downstreamnt
atgcgtcaattccccaaaacaagttttgacatttcccctgaaatgtcattctctatctat
tcactgcaagtgcctgctgttccaggccttacctgctgggcactaacggcggagccagga
tggggacagaataaaggagccacgacctgtggcaccaactcgcactcagactctgaactc
agacctgaaatcttctcttcatgggaggctcggcagtttttcttactcctgtggtctcca
gatttcaggcctaagatgaaagcctctagtcttgccttcagccttctctctgctgcgttt
tatctcctatggactccttccactggactgaagacactcaatttgggaagctgtgtgatc
gccacaaaccttcaggaaatacgaaatggattttctgagatacggggcagtgtgcaagcc
aaagatggaaacattgacatcagaatcttaaggaggactgagtctttgcaagacacaaag
cctgcgaatcgatgctgcctcctgcgccatttgctaagactgtatctggacagggtattt
aaaaactaccagacccctgaccattatactctccggaagatcagcagccttgccaattcc
tttcttaccatcaagaaggacctccggctctgtcatgcccacatgacatgccattgtggg
gaggaagcaatgaagaaatacagccagattctgagtcactttgaaaagctggaacctcag
gcagcagttgtgaaggctttgggggaactagacattcttctgcaatggatggaggagaca
gaatag

KEGG   Pan paniscus (bonobo): 100989950
Entry
100989950         CDS       T02283                                 

Gene name
IL12B
Definition
(RefSeq) interleukin 12B
  KO
K05425  interleukin 12B
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04620  Toll-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04625  C-type lectin receptor signaling pathway
pps04630  JAK-STAT signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps04940  Type I diabetes mellitus
pps05133  Pertussis
pps05134  Legionellosis
pps05140  Leishmaniasis
pps05142  Chagas disease
pps05143  African trypanosomiasis
pps05145  Toxoplasmosis
pps05146  Amoebiasis
pps05152  Tuberculosis
pps05162  Measles
pps05164  Influenza A
pps05168  Herpes simplex virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05205  Proteoglycans in cancer
pps05321  Inflammatory bowel disease
pps05330  Allograft rejection
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100989950 (IL12B)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100989950 (IL12B)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100989950 (IL12B)
   04622 RIG-I-like receptor signaling pathway
    100989950 (IL12B)
   04625 C-type lectin receptor signaling pathway
    100989950 (IL12B)
   04658 Th1 and Th2 cell differentiation
    100989950 (IL12B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100989950 (IL12B)
   05205 Proteoglycans in cancer
    100989950 (IL12B)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    100989950 (IL12B)
   05164 Influenza A
    100989950 (IL12B)
   05162 Measles
    100989950 (IL12B)
   05168 Herpes simplex virus 1 infection
    100989950 (IL12B)
  09171 Infectious disease: bacterial
   05133 Pertussis
    100989950 (IL12B)
   05134 Legionellosis
    100989950 (IL12B)
   05152 Tuberculosis
    100989950 (IL12B)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100989950 (IL12B)
   05145 Toxoplasmosis
    100989950 (IL12B)
   05140 Leishmaniasis
    100989950 (IL12B)
   05142 Chagas disease
    100989950 (IL12B)
   05143 African trypanosomiasis
    100989950 (IL12B)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100989950 (IL12B)
   05330 Allograft rejection
    100989950 (IL12B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100989950 (IL12B)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    100989950 (IL12B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100989950 (IL12B)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100989950 (IL12B)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100989950 (IL12B)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Cytokines
   100989950 (IL12B)
SSDB
Motif
Pfam: IL12p40_C Ig_5 Ig_3 Ig_4 fn3 Ig_2 I-set
Other DBs
NCBI-GeneID: 100989950
NCBI-ProteinID: XP_003819049
UniProt: A0A2R9BID0
Position
5
AA seq 328 aa
MCHQQLVISWFSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITW
TSDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGKVLSHSLLLLHKKEDGIWSTDILKDQ
KEPKTKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERV
RGDNKEYEYSVECQEDSACPAAEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKN
LQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATVIC
RKNASISVRAQDRYYSSSWSEWASVPCS
NT seq 987 nt   +upstreamnt  +downstreamnt
atgtgtcaccagcagttggtcatctcttggttttccctggtttttctggcatctcccctc
gtggccatatgggaactgaagaaagatgtttatgtcgtagaattggattggtatccggat
gcccctggagaaatggtggtcctcacctgtgacacccctgaagaagatggtatcacctgg
acctcggaccagagcagtgaggtcttaggctctggcaaaaccctgaccatccaagtcaaa
gagtttggagatgctggccagtacacctgtcacaaaggaggcaaggttctaagccattca
ctcctgctgcttcacaaaaaggaagatggaatttggtccactgatattttaaaggaccag
aaagaacccaaaactaagacctttctaagatgcgaggccaagaattattcaggacgtttc
acctgctggtggctgacgacaatcagtactgatttgacattcagtgtcaaaagcagcaga
ggctcttctgacccccaaggggtgacgtgcggagctgctacactctctgcagagagggtc
agaggggacaacaaggagtatgagtactcagtggagtgccaggaggacagtgcctgccca
gctgctgaggagagtctgcccattgaggtcatggtggatgctgttcacaagctcaagtat
gaaaactacaccagcagcttcttcatcagggacatcatcaaacctgacccacccaagaac
ttgcagctgaagccattaaagaattctcggcaggtggaggtcagctgggagtaccctgac
acctggagtactccacattcctacttctccctgacattctgcgttcaggtccagggcaag
agcaagagagaaaagaaagatagagtcttcacggacaagacctcagccacagtcatctgc
cgcaaaaatgccagcattagcgtgcgggcccaggaccgctactatagctcatcttggagc
gaatgggcatctgtgccctgcagttag

KEGG   Pan paniscus (bonobo): 100990188
Entry
100990188         CDS       T02283                                 

Gene name
IL19
Definition
(RefSeq) interleukin 19
  KO
K05444  interleukin 19
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100990188 (IL19)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100990188 (IL19)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100990188 (IL19)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100990188 (IL19)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100990188 (IL19)
SSDB
Motif
Pfam: IL10 MIF4G Cas5fv_helical
Other DBs
NCBI-GeneID: 100990188
NCBI-ProteinID: XP_003822964
UniProt: A0A2R9B3D8
Position
1
AA seq 177 aa
MKLQCVSLWLLGTILILCSVDNHGLRRCLISTDMHHIEESFQEIKRAIQAKDTFPNVTIL
STLETLQIIKPLDVCCVTKNLLEFYVDRVFKDHQEPNPKILRKVSSIANSFLYMQKTLRQ
CQEQRQCHCRQEATNATRVIHDNYDQLEVRAAAIKSLGELDVFLAWINKNHEVTSSA
NT seq 534 nt   +upstreamnt  +downstreamnt
atgaagttacagtgtgtttccctttggcttctgggtacaatactgatattgtgctcagta
gacaaccacggtctcaggagatgtctgatttccacagacatgcaccatatagaagagagt
ttccaagaaatcaaaagagccatccaagctaaggacaccttcccaaatgtcactatcctg
tccacattggagactctgcagatcattaagcccttagatgtgtgctgcgtgaccaagaac
ctcctggagttctacgtggacagggtgttcaaggatcatcaggagccaaaccccaaaatc
ttgagaaaagtcagcagcattgccaactctttcctctacatgcagaaaactctgcggcaa
tgtcaggaacagaggcagtgtcactgcaggcaggaagccaccaatgccaccagagtcatc
cacgacaactatgatcagctggaggtccgcgctgctgccattaaatccctgggagagctc
gatgtctttctagcctggattaataagaatcatgaagtaacgtcctcagcttga

KEGG   Pan paniscus (bonobo): 100990760
Entry
100990760         CDS       T02283                                 

Gene name
IL10
Definition
(RefSeq) interleukin 10
  KO
K05443  interleukin 10
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04061  Viral protein interaction with cytokine and cytokine receptor
pps04068  FoxO signaling pathway
pps04625  C-type lectin receptor signaling pathway
pps04630  JAK-STAT signaling pathway
pps04660  T cell receptor signaling pathway
pps04672  Intestinal immune network for IgA production
pps05133  Pertussis
pps05135  Yersinia infection
pps05140  Leishmaniasis
pps05142  Chagas disease
pps05143  African trypanosomiasis
pps05144  Malaria
pps05145  Toxoplasmosis
pps05146  Amoebiasis
pps05150  Staphylococcus aureus infection
pps05152  Tuberculosis
pps05310  Asthma
pps05320  Autoimmune thyroid disease
pps05321  Inflammatory bowel disease
pps05322  Systemic lupus erythematosus
pps05330  Allograft rejection
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100990760 (IL10)
   04068 FoxO signaling pathway
    100990760 (IL10)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100990760 (IL10)
   04061 Viral protein interaction with cytokine and cytokine receptor
    100990760 (IL10)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100990760 (IL10)
   04660 T cell receptor signaling pathway
    100990760 (IL10)
   04672 Intestinal immune network for IgA production
    100990760 (IL10)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100990760 (IL10)
   05133 Pertussis
    100990760 (IL10)
   05150 Staphylococcus aureus infection
    100990760 (IL10)
   05152 Tuberculosis
    100990760 (IL10)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100990760 (IL10)
   05144 Malaria
    100990760 (IL10)
   05145 Toxoplasmosis
    100990760 (IL10)
   05140 Leishmaniasis
    100990760 (IL10)
   05142 Chagas disease
    100990760 (IL10)
   05143 African trypanosomiasis
    100990760 (IL10)
  09163 Immune disease
   05310 Asthma
    100990760 (IL10)
   05322 Systemic lupus erythematosus
    100990760 (IL10)
   05320 Autoimmune thyroid disease
    100990760 (IL10)
   05321 Inflammatory bowel disease
    100990760 (IL10)
   05330 Allograft rejection
    100990760 (IL10)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100990760 (IL10)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100990760 (IL10)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100990760 (IL10)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Cytokines
   100990760 (IL10)
SSDB
Motif
Pfam: IL10 IL22 CLZ
Other DBs
NCBI-GeneID: 100990760
NCBI-ProteinID: XP_003822966
UniProt: A0A2R8ZE59
Position
1
AA seq 178 aa
MHSSALLCCLVLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMKDQ
LDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKVHVNSLGENLKTLR
LRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTMKIRN
NT seq 537 nt   +upstreamnt  +downstreamnt
atgcacagctcagcactgctctgttgcctggtcctcctgactggggtgagggccagccca
ggccagggcacccagtctgagaacagctgcacccacttcccaggcaacctgcctaacatg
cttcgagatctccgagatgccttcagcagagtgaagactttctttcaaatgaaggatcag
ctggacaacttgttgttaaaggagtccttgctggaggactttaagggttacctgggttgc
caagccttgtctgagatgatccagttttacctggaggaggtgatgccccaagctgagaac
caagacccagacatcaaggtgcatgtgaactccctgggggagaacctgaagaccctcagg
ctgaggctacggcgctgtcatcgatttcttccctgtgaaaacaagagcaaggccgtggag
caggtgaagaatgcctttaataagctccaagagaaaggcatctacaaagccatgagtgag
tttgacatcttcatcaactacatagaagcctacatgacaatgaagatacgaaactga

KEGG   Pan paniscus (bonobo): 100991249
Entry
100991249         CDS       T02283                                 

Gene name
IL5
Definition
(RefSeq) interleukin 5
  KO
K05428  interleukin 5
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps04657  IL-17 signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps04660  T cell receptor signaling pathway
pps04664  Fc epsilon RI signaling pathway
pps04672  Intestinal immune network for IgA production
pps05200  Pathways in cancer
pps05310  Asthma
pps05320  Autoimmune thyroid disease
pps05321  Inflammatory bowel disease
pps05330  Allograft rejection
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100991249 (IL5)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100991249 (IL5)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100991249 (IL5)
   04660 T cell receptor signaling pathway
    100991249 (IL5)
   04658 Th1 and Th2 cell differentiation
    100991249 (IL5)
   04657 IL-17 signaling pathway
    100991249 (IL5)
   04664 Fc epsilon RI signaling pathway
    100991249 (IL5)
   04672 Intestinal immune network for IgA production
    100991249 (IL5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100991249 (IL5)
  09163 Immune disease
   05310 Asthma
    100991249 (IL5)
   05320 Autoimmune thyroid disease
    100991249 (IL5)
   05321 Inflammatory bowel disease
    100991249 (IL5)
   05330 Allograft rejection
    100991249 (IL5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100991249 (IL5)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100991249 (IL5)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100991249 (IL5)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Cytokines
   100991249 (IL5)
SSDB
Motif
Pfam: IL5 DUF6034
Other DBs
NCBI-GeneID: 100991249
NCBI-ProteinID: XP_003829353
UniProt: A0A2R9CIQ9
Position
5
AA seq 134 aa
MRMLLHLSLLALGAAYVYAIPTEIPTSALVKETLALLSTHRTLLIANETLRIPVPVHKNH
QLCTEEIFQGIGTLESQTVQGGTVERLFKNLSLIKKYIDGQKKKCGEERRRVNQFLDYLQ
EFLGVMNTEWIIES
NT seq 405 nt   +upstreamnt  +downstreamnt
atgaggatgcttctgcatttgagtttgctagctcttggagctgcctacgtgtatgccatc
cccacagaaattcccacaagtgcattggtgaaagagaccttggcactgctttctactcat
cgaactctgctgatagccaatgagactctgaggattcctgttcctgtacataaaaatcac
caactgtgcactgaagaaatctttcagggaataggcacactggagagtcaaactgtgcaa
gggggtactgtggaaagactattcaaaaacttgtccttaataaagaaatacattgacggc
caaaaaaaaaagtgtggagaagaaagacggagagtaaaccaattcctagactacctgcaa
gagtttcttggtgtaatgaacaccgagtggataatagaaagttga

KEGG   Pan paniscus (bonobo): 100991779
Entry
100991779         CDS       T02283                                 

Gene name
IFNG
Definition
(RefSeq) interferon gamma
  KO
K04687  interferon gamma
Organism
pps  Pan paniscus (bonobo)
Pathway
pps03050  Proteasome
pps04060  Cytokine-cytokine receptor interaction
pps04066  HIF-1 signaling pathway
pps04217  Necroptosis
pps04350  TGF-beta signaling pathway
pps04380  Osteoclast differentiation
pps04612  Antigen processing and presentation
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps04657  IL-17 signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps04660  T cell receptor signaling pathway
pps04940  Type I diabetes mellitus
pps05140  Leishmaniasis
pps05142  Chagas disease
pps05143  African trypanosomiasis
pps05144  Malaria
pps05145  Toxoplasmosis
pps05146  Amoebiasis
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05164  Influenza A
pps05168  Herpes simplex virus 1 infection
pps05200  Pathways in cancer
pps05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pps05321  Inflammatory bowel disease
pps05322  Systemic lupus erythematosus
pps05323  Rheumatoid arthritis
pps05330  Allograft rejection
pps05332  Graft-versus-host disease
pps05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03050 Proteasome
    100991779 (IFNG)
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    100991779 (IFNG)
   04630 JAK-STAT signaling pathway
    100991779 (IFNG)
   04066 HIF-1 signaling pathway
    100991779 (IFNG)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100991779 (IFNG)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100991779 (IFNG)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100991779 (IFNG)
   04612 Antigen processing and presentation
    100991779 (IFNG)
   04660 T cell receptor signaling pathway
    100991779 (IFNG)
   04658 Th1 and Th2 cell differentiation
    100991779 (IFNG)
   04659 Th17 cell differentiation
    100991779 (IFNG)
   04657 IL-17 signaling pathway
    100991779 (IFNG)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100991779 (IFNG)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100991779 (IFNG)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100991779 (IFNG)
  09172 Infectious disease: viral
   05160 Hepatitis C
    100991779 (IFNG)
   05164 Influenza A
    100991779 (IFNG)
   05168 Herpes simplex virus 1 infection
    100991779 (IFNG)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100991779 (IFNG)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100991779 (IFNG)
   05144 Malaria
    100991779 (IFNG)
   05145 Toxoplasmosis
    100991779 (IFNG)
   05140 Leishmaniasis
    100991779 (IFNG)
   05142 Chagas disease
    100991779 (IFNG)
   05143 African trypanosomiasis
    100991779 (IFNG)
  09163 Immune disease
   05322 Systemic lupus erythematosus
    100991779 (IFNG)
   05323 Rheumatoid arthritis
    100991779 (IFNG)
   05321 Inflammatory bowel disease
    100991779 (IFNG)
   05330 Allograft rejection
    100991779 (IFNG)
   05332 Graft-versus-host disease
    100991779 (IFNG)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100991779 (IFNG)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    100991779 (IFNG)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03051 Proteasome [BR:pps03051]
    100991779 (IFNG)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100991779 (IFNG)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100991779 (IFNG)
Proteasome [BR:pps03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    100991779 (IFNG)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100991779 (IFNG)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Cytokines
   100991779 (IFNG)
SSDB
Motif
Pfam: IFN-gamma API5 Cna_B Tup_N
Other DBs
NCBI-GeneID: 100991779
NCBI-ProteinID: XP_003808753
UniProt: A0A2R9CC85
Position
12
AA seq 166 aa
MKYTSYILAFQLCIVLGSLGCYCQDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWK
EESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTN
YSVTDLNVQRKAIHELIQVMAELSPAVKTGKRKRSQMLFRGRRASQ
NT seq 501 nt   +upstreamnt  +downstreamnt
atgaaatatacaagttatatcttggcttttcagctctgcatcgttttgggttctcttggc
tgttactgccaggacccatatgtaaaagaagcagaaaaccttaagaaatattttaatgca
ggtcattcagatgtagcagataatggaactcttttcttaggcattttgaagaattggaaa
gaggagagtgacagaaaaataatgcagagccaaattgtctccttttacttcaaacttttt
aaaaactttaaagatgaccagagcatccaaaagagtgtggagaccatcaaggaagacatg
aatgtcaagtttttcaatagcaacaaaaagaaacgagatgacttcgaaaagctgactaat
tattcggtaactgacttgaatgtccaacgcaaagcaatacatgaactcatccaagtgatg
gctgaactgtcgccagcagttaaaacggggaagcgaaaaaggagtcagatgctgtttcga
ggtcgaagagcatcccagtaa

KEGG   Pan paniscus (bonobo): 100992466
Entry
100992466         CDS       T02283                                 

Gene name
IL22
Definition
(RefSeq) interleukin 22
  KO
K05445  interleukin 22
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04659  Th17 cell differentiation
pps05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100992466 (IL22)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100992466 (IL22)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100992466 (IL22)
 09160 Human Diseases
  09163 Immune disease
   05321 Inflammatory bowel disease
    100992466 (IL22)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100992466 (IL22)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interleukins
   100992466 (IL22)
SSDB
Motif
Pfam: IL22 IL10 IL28A
Other DBs
NCBI-GeneID: 100992466
NCBI-ProteinID: XP_003808755
UniProt: A0A2R8ZS67
Position
12
AA seq 179 aa
MAALQKSVSSFLMGTLATSCLLLLALLVQGGAAAPISSHCRLDKSNFQQPYITNRTFMLA
KEASLADNNTDVRLIGEKLFHGVSMSERCYLMKQVLNFTLEEVLFPQSDRFQPYMQEVVP
FLARLSNRLSTCHIEGDDLHIQRNVQKLKDTVKKLGENGEIKAIGELDLLFMSLRNACI
NT seq 540 nt   +upstreamnt  +downstreamnt
atggccgccctgcagaaatctgtgagctctttccttatggggaccctggccaccagctgc
ctccttctcttggccctcttggtacagggaggagcagctgcgcccatcagctcccactgc
aggcttgacaagtccaacttccagcagccctatatcaccaaccgcaccttcatgctggct
aaggaggctagcttggctgataacaacacagacgttcgtctcattggggagaaactgttc
cacggagtcagtatgagtgagcgctgctatctgatgaagcaggtgctgaacttcaccctt
gaagaagtgctgttccctcaatctgataggttccagccttatatgcaggaggtggtgccc
ttcctggccaggctcagcaacaggctaagcacatgtcatattgaaggtgatgacctgcat
atccagaggaatgtgcaaaagctgaaggacacagtgaaaaagcttggagagaatggagag
atcaaagcaattggagaactggatttgctgtttatgtctctgagaaatgcctgcatttga

KEGG   Pan paniscus (bonobo): 100995734
Entry
100995734         CDS       T02283                                 

Gene name
IFNA5
Definition
(RefSeq) interferon alpha-5
  KO
K05414  interferon alpha
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05320  Autoimmune thyroid disease
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100995734 (IFNA5)
   04151 PI3K-Akt signaling pathway
    100995734 (IFNA5)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100995734 (IFNA5)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100995734 (IFNA5)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100995734 (IFNA5)
   04621 NOD-like receptor signaling pathway
    100995734 (IFNA5)
   04622 RIG-I-like receptor signaling pathway
    100995734 (IFNA5)
   04623 Cytosolic DNA-sensing pathway
    100995734 (IFNA5)
   04650 Natural killer cell mediated cytotoxicity
    100995734 (IFNA5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100995734 (IFNA5)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100995734 (IFNA5)
   05161 Hepatitis B
    100995734 (IFNA5)
   05160 Hepatitis C
    100995734 (IFNA5)
   05171 Coronavirus disease - COVID-19
    100995734 (IFNA5)
   05164 Influenza A
    100995734 (IFNA5)
   05162 Measles
    100995734 (IFNA5)
   05168 Herpes simplex virus 1 infection
    100995734 (IFNA5)
   05163 Human cytomegalovirus infection
    100995734 (IFNA5)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100995734 (IFNA5)
   05169 Epstein-Barr virus infection
    100995734 (IFNA5)
   05165 Human papillomavirus infection
    100995734 (IFNA5)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100995734 (IFNA5)
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100995734 (IFNA5)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100995734 (IFNA5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100995734 (IFNA5)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100995734 (IFNA5)
SSDB
Motif
Pfam: Interferon iSTAND CBF ORF6C
Other DBs
NCBI-GeneID: 100995734
NCBI-ProteinID: XP_008954341
Position
9
AA seq 181 aa
MALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFGFPQEEFDG
NQFQKAQAISILHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLEACMMQEVG
VEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSTNLQERLRRK
E
NT seq 546 nt   +upstreamnt  +downstreamnt
atggccctggtggtgctcaactgcaagtcaatctgttctctgggctgtgatctgcctcag
acccacagcctgagtaacaggaggactttgatgatcatggcacaaatgggaagaatctct
cctttctcctgcctgaaggacagacatgactttggatttcctcaggaggagtttgatggc
aaccagttccagaaggctcaagccatctctatcctccatgagatgatccagcagaccttc
aatctcttcagcacaaaggactcatctgctacttgggatgagacacttctagacaaattc
tatactgaactttaccagcagctgaatgacctggaagcctgtatgatgcaggaggttgga
gtggaagacactcctctgatgaatgtggactctatcctgactgtgagaaaatactttcaa
agaatcactctctatctgacagagaagaaatacagcccttgtgcatgggaggttgttaga
gcagaaatcatgagatccttctctttatcaacaaacttgcaagaaagattaaggaggaag
gaatga

KEGG   Pan paniscus (bonobo): 100995851
Entry
100995851         CDS       T02283                                 

Gene name
IFNB1
Definition
(RefSeq) interferon beta 1
  KO
K05415  interferon beta
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04217  Necroptosis
pps04380  Osteoclast differentiation
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps04668  TNF signaling pathway
pps05135  Yersinia infection
pps05142  Chagas disease
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100995851 (IFNB1)
   04668 TNF signaling pathway
    100995851 (IFNB1)
   04151 PI3K-Akt signaling pathway
    100995851 (IFNB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100995851 (IFNB1)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100995851 (IFNB1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100995851 (IFNB1)
   04621 NOD-like receptor signaling pathway
    100995851 (IFNB1)
   04622 RIG-I-like receptor signaling pathway
    100995851 (IFNB1)
   04623 Cytosolic DNA-sensing pathway
    100995851 (IFNB1)
   04650 Natural killer cell mediated cytotoxicity
    100995851 (IFNB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100995851 (IFNB1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100995851 (IFNB1)
   05161 Hepatitis B
    100995851 (IFNB1)
   05160 Hepatitis C
    100995851 (IFNB1)
   05171 Coronavirus disease - COVID-19
    100995851 (IFNB1)
   05164 Influenza A
    100995851 (IFNB1)
   05162 Measles
    100995851 (IFNB1)
   05168 Herpes simplex virus 1 infection
    100995851 (IFNB1)
   05163 Human cytomegalovirus infection
    100995851 (IFNB1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100995851 (IFNB1)
   05169 Epstein-Barr virus infection
    100995851 (IFNB1)
   05165 Human papillomavirus infection
    100995851 (IFNB1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100995851 (IFNB1)
   05152 Tuberculosis
    100995851 (IFNB1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    100995851 (IFNB1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100995851 (IFNB1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100995851 (IFNB1)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100995851 (IFNB1)
SSDB
Motif
Pfam: Interferon Forkhead Ribosomal_S15
Other DBs
NCBI-GeneID: 100995851
NCBI-ProteinID: XP_003830711
Position
9
AA seq 187 aa
MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNIQCQKLLWQLSGRLEYCLKDRMNFD
IPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLK
TVLEEKPEKEDFTRGKFMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINR
LAGYLRN
NT seq 564 nt   +upstreamnt  +downstreamnt
atgaccaacaagtgtctcctccaaattgctctcctgttgtgcttctccactacagctctt
tccatgagctacaacttgcttggattcctacaaagaagcagcaatattcagtgtcagaag
ctcctgtggcaattgagtgggaggcttgaatattgcctcaaggacaggatgaactttgac
atccctgaggagattaagcagctgcagcagttccagaaggaggacgccgcattgaccatc
tatgagatgctccagaacatctttgctattttcagacaagattcatctagcactggctgg
aatgagactattgttgagaacctcctggctaatgtctatcatcagataaaccatctgaag
acagtcctggaagaaaaaccggagaaagaagatttcaccaggggaaaattcatgagcagt
ctgcacctgaaaagatattatgggagaattctgcattacctgaaggccaaggagtacagt
cactgtgcctggaccatagtcagagtggaaatcctaaggaacttttacttcattaacaga
cttgcaggttacctccgaaactga

KEGG   Pan paniscus (bonobo): 100995954
Entry
100995954         CDS       T02283                                 

Gene name
CSF2
Definition
(RefSeq) colony stimulating factor 2
  KO
K05427  granulocyte-macrophage colony-stimulating factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04630  JAK-STAT signaling pathway
pps04640  Hematopoietic cell lineage
pps04650  Natural killer cell mediated cytotoxicity
pps04657  IL-17 signaling pathway
pps04660  T cell receptor signaling pathway
pps04664  Fc epsilon RI signaling pathway
pps04668  TNF signaling pathway
pps05146  Amoebiasis
pps05166  Human T-cell leukemia virus 1 infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05171  Coronavirus disease - COVID-19
pps05202  Transcriptional misregulation in cancer
pps05221  Acute myeloid leukemia
pps05323  Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100995954 (CSF2)
   04668 TNF signaling pathway
    100995954 (CSF2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100995954 (CSF2)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100995954 (CSF2)
   04650 Natural killer cell mediated cytotoxicity
    100995954 (CSF2)
   04660 T cell receptor signaling pathway
    100995954 (CSF2)
   04657 IL-17 signaling pathway
    100995954 (CSF2)
   04664 Fc epsilon RI signaling pathway
    100995954 (CSF2)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    100995954 (CSF2)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    100995954 (CSF2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100995954 (CSF2)
   05171 Coronavirus disease - COVID-19
    100995954 (CSF2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100995954 (CSF2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100995954 (CSF2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    100995954 (CSF2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:pps03019]
    100995954 (CSF2)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100995954 (CSF2)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100995954 (CSF2)
Messenger RNA biogenesis [BR:pps03019]
 Eukaryotic type
  mRNA degradation factors
   3'-5' decay
    Other 3'-5' decay factors
     100995954 (CSF2)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  CSF and other factors
   100995954 (CSF2)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Cytokines
   100995954 (CSF2)
SSDB
Motif
Pfam: GM_CSF
Other DBs
NCBI-GeneID: 100995954
NCBI-ProteinID: XP_003829363
UniProt: A0A2R9C4M7
Position
5
AA seq 144 aa
MWLQSLLLLGTVACSISAPARSPSPSTQPWEHVNAIQEARRLLNLSRDTAAEMNETVEVV
SEMFDLQEPTCLQTRLELYKQGLRGSLTKLKGPLTMMASHYKQHCPPTPETSCATQIITF
ESFKENLKDFLLVIPLDCWEPVQE
NT seq 435 nt   +upstreamnt  +downstreamnt
atgtggctgcagagcctgctgctcttgggcactgtggcctgcagcatctctgcacccgcc
cgctcgcccagccccagcacgcagccctgggagcatgtgaatgccatccaggaggcccgg
cgtctcctgaacctgagtagagacactgctgctgagatgaatgaaacagtagaagttgtc
tcagaaatgtttgacctccaggagccgacctgcctacagacccgcctggagctgtacaag
cagggcctgcggggcagcctcaccaagctcaagggccccttgaccatgatggccagccac
tacaagcagcactgccctccaaccccggaaacttcctgtgcaacccagattatcaccttt
gaaagtttcaaagagaacctgaaggactttctgcttgtcatccccttggactgctgggag
ccagtccaggagtga

KEGG   Pan paniscus (bonobo): 100996206
Entry
100996206         CDS       T02283                                 

Gene name
IFNW1
Definition
(RefSeq) interferon omega 1
  KO
K05440  interferon omega
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04060  Cytokine-cytokine receptor interaction
pps04622  RIG-I-like receptor signaling pathway
pps04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100996206 (IFNW1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100996206 (IFNW1)
 09150 Organismal Systems
  09151 Immune system
   04622 RIG-I-like receptor signaling pathway
    100996206 (IFNW1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100996206 (IFNW1)
Cytokines and growth factors [BR:pps04052]
 Cytokines
  Interferons
   100996206 (IFNW1)
SSDB
Motif
Pfam: Interferon
Other DBs
NCBI-GeneID: 100996206
NCBI-ProteinID: XP_003830712
UniProt: A0A2R8ZQW8
Position
9
AA seq 200 aa
MALLFPLLAALVMTSYSPVGSLGCDLPQNHGLLSRNTLVLLHQMRRISPFLCLKDRRDFR
FPQEMVKGSQLQKAQVMSFLHEMLQQIFSLFHTERSSAAWNMTLLDQLHTGLHQQLQHLE
TCLLQVMGEGESAGAISSPALTLRRYFQGIRVYLKEKKYSDCAWEVVRMEIMKSLFLSTN
MQERLRSKDRDLGSSRNDSH
NT seq 603 nt   +upstreamnt  +downstreamnt
atggccctcctgttccctctactggcagccctagtgatgaccagctatagccctgttgga
tctctgggctgtgatctgcctcagaaccatggcctacttagcaggaacaccttggtactt
ctgcaccaaatgaggagaatctcccctttcttgtgtctcaaggacagaagagatttcagg
ttcccccaggagatggtaaaagggagccagttgcagaaggcccaggtcatgtctttcctc
catgagatgctgcagcagatcttcagcctcttccacacagagcgctcctctgctgcctgg
aacatgaccctcctagaccaactccacactggacttcatcagcaactgcaacacctggag
acctgcttgctgcaggtaatgggagaaggagaatctgctggggcaattagcagccctgca
ctgaccttgaggaggtacttccagggaatccgtgtctacctgaaagagaagaaatacagc
gactgtgcctgggaagttgtcagaatggaaatcatgaaatccttgttcttatcaacaaac
atgcaagaaagactgagaagtaaagatagagacctgggctcatctcgaaatgattctcat
tga

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