KEGG   Pan paniscus (bonobo): 100979341
Entry
100979341         CDS       T02283                                 
Symbol
NFKB1
Name
(RefSeq) nuclear factor NF-kappa-B p105 subunit isoform X1
  KO
K02580  nuclear factor NF-kappa-B p105 subunit
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01523  Antifolate resistance
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04024  cAMP signaling pathway
pps04062  Chemokine signaling pathway
pps04064  NF-kappa B signaling pathway
pps04066  HIF-1 signaling pathway
pps04071  Sphingolipid signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04210  Apoptosis
pps04211  Longevity regulating pathway
pps04218  Cellular senescence
pps04380  Osteoclast differentiation
pps04613  Neutrophil extracellular trap formation
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04625  C-type lectin receptor signaling pathway
pps04657  IL-17 signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps04660  T cell receptor signaling pathway
pps04662  B cell receptor signaling pathway
pps04668  TNF signaling pathway
pps04722  Neurotrophin signaling pathway
pps04917  Prolactin signaling pathway
pps04920  Adipocytokine signaling pathway
pps04926  Relaxin signaling pathway
pps04931  Insulin resistance
pps04932  Non-alcoholic fatty liver disease
pps04933  AGE-RAGE signaling pathway in diabetic complications
pps04936  Alcoholic liver disease
pps05010  Alzheimer disease
pps05022  Pathways of neurodegeneration - multiple diseases
pps05030  Cocaine addiction
pps05132  Salmonella infection
pps05133  Pertussis
pps05134  Legionellosis
pps05135  Yersinia infection
pps05140  Leishmaniasis
pps05142  Chagas disease
pps05145  Toxoplasmosis
pps05146  Amoebiasis
pps05152  Tuberculosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05166  Human T-cell leukemia virus 1 infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05202  Transcriptional misregulation in cancer
pps05203  Viral carcinogenesis
pps05206  MicroRNAs in cancer
pps05207  Chemical carcinogenesis - receptor activation
pps05208  Chemical carcinogenesis - reactive oxygen species
pps05212  Pancreatic cancer
pps05215  Prostate cancer
pps05220  Chronic myeloid leukemia
pps05221  Acute myeloid leukemia
pps05222  Small cell lung cancer
pps05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pps05321  Inflammatory bowel disease
pps05415  Diabetic cardiomyopathy
pps05417  Lipid and atherosclerosis
pps05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100979341 (NFKB1)
   04014 Ras signaling pathway
    100979341 (NFKB1)
   04064 NF-kappa B signaling pathway
    100979341 (NFKB1)
   04668 TNF signaling pathway
    100979341 (NFKB1)
   04066 HIF-1 signaling pathway
    100979341 (NFKB1)
   04071 Sphingolipid signaling pathway
    100979341 (NFKB1)
   04024 cAMP signaling pathway
    100979341 (NFKB1)
   04151 PI3K-Akt signaling pathway
    100979341 (NFKB1)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    100979341 (NFKB1)
   04218 Cellular senescence
    100979341 (NFKB1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    100979341 (NFKB1)
   04620 Toll-like receptor signaling pathway
    100979341 (NFKB1)
   04621 NOD-like receptor signaling pathway
    100979341 (NFKB1)
   04622 RIG-I-like receptor signaling pathway
    100979341 (NFKB1)
   04623 Cytosolic DNA-sensing pathway
    100979341 (NFKB1)
   04625 C-type lectin receptor signaling pathway
    100979341 (NFKB1)
   04660 T cell receptor signaling pathway
    100979341 (NFKB1)
   04658 Th1 and Th2 cell differentiation
    100979341 (NFKB1)
   04659 Th17 cell differentiation
    100979341 (NFKB1)
   04657 IL-17 signaling pathway
    100979341 (NFKB1)
   04662 B cell receptor signaling pathway
    100979341 (NFKB1)
   04062 Chemokine signaling pathway
    100979341 (NFKB1)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    100979341 (NFKB1)
   04917 Prolactin signaling pathway
    100979341 (NFKB1)
   04926 Relaxin signaling pathway
    100979341 (NFKB1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100979341 (NFKB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100979341 (NFKB1)
  09149 Aging
   04211 Longevity regulating pathway
    100979341 (NFKB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100979341 (NFKB1)
   05202 Transcriptional misregulation in cancer
    100979341 (NFKB1)
   05206 MicroRNAs in cancer
    100979341 (NFKB1)
   05207 Chemical carcinogenesis - receptor activation
    100979341 (NFKB1)
   05208 Chemical carcinogenesis - reactive oxygen species
    100979341 (NFKB1)
   05203 Viral carcinogenesis
    100979341 (NFKB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100979341 (NFKB1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100979341 (NFKB1)
   05221 Acute myeloid leukemia
    100979341 (NFKB1)
   05220 Chronic myeloid leukemia
    100979341 (NFKB1)
   05215 Prostate cancer
    100979341 (NFKB1)
   05222 Small cell lung cancer
    100979341 (NFKB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100979341 (NFKB1)
   05170 Human immunodeficiency virus 1 infection
    100979341 (NFKB1)
   05161 Hepatitis B
    100979341 (NFKB1)
   05160 Hepatitis C
    100979341 (NFKB1)
   05171 Coronavirus disease - COVID-19
    100979341 (NFKB1)
   05164 Influenza A
    100979341 (NFKB1)
   05162 Measles
    100979341 (NFKB1)
   05168 Herpes simplex virus 1 infection
    100979341 (NFKB1)
   05163 Human cytomegalovirus infection
    100979341 (NFKB1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100979341 (NFKB1)
   05169 Epstein-Barr virus infection
    100979341 (NFKB1)
   05165 Human papillomavirus infection
    100979341 (NFKB1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100979341 (NFKB1)
   05135 Yersinia infection
    100979341 (NFKB1)
   05133 Pertussis
    100979341 (NFKB1)
   05134 Legionellosis
    100979341 (NFKB1)
   05152 Tuberculosis
    100979341 (NFKB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100979341 (NFKB1)
   05145 Toxoplasmosis
    100979341 (NFKB1)
   05140 Leishmaniasis
    100979341 (NFKB1)
   05142 Chagas disease
    100979341 (NFKB1)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100979341 (NFKB1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100979341 (NFKB1)
   05022 Pathways of neurodegeneration - multiple diseases
    100979341 (NFKB1)
  09165 Substance dependence
   05030 Cocaine addiction
    100979341 (NFKB1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100979341 (NFKB1)
   05418 Fluid shear stress and atherosclerosis
    100979341 (NFKB1)
   05415 Diabetic cardiomyopathy
    100979341 (NFKB1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100979341 (NFKB1)
   04932 Non-alcoholic fatty liver disease
    100979341 (NFKB1)
   04931 Insulin resistance
    100979341 (NFKB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100979341 (NFKB1)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100979341 (NFKB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:pps03000]
    100979341 (NFKB1)
Transcription factors [BR:pps03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    100979341 (NFKB1)
SSDB
Motif
Pfam: RHD_DNA_bind RHD_dimer Ank_2 Ank Ank_4 Ank_3 Ank_5 Death
Other DBs
NCBI-GeneID: 100979341
NCBI-ProteinID: XP_003830003
Ensembl: ENSPPAG00000032087
UniProt: A0A2R9AST7
Position
3:100585471..100700918
AA seq 969 aa
MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTADGPYLQILEQPKQRGFRFRY
VCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCE
DGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQ
AEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAI
YDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGD
FSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEV
QRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITF
HPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNG
EVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQ
DENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVE
DLLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSVLLKHKKAALLLDHPNGDGLNAIHLAM
MSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDG
TTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMA
TSWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKL
GLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTS
QAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYG
QEGPLEGKI
NT seq 2910 nt   +upstreamnt  +downstreamnt
atggcagaagatgatccatatttgggaaggcctgaacaaatgtttcatttggatccttct
ttgactcatacaatatttaatccagaagtatttcaaccacagatggcactgccaacagca
gatggcccataccttcaaatattagagcaacctaaacagagaggatttcgtttccgttat
gtatgtgaaggcccatcccatggtggactacctggtgcctctagcgaaaagaacaagaag
tcttaccctcaggtcaaaatctgcaactatgtgggaccagcaaaggttattgttcagttg
gtcacaaatggaaaaaatatccacctgcatgcccacagcctggtgggaaaacactgtgag
gatgggatctgcactgtaactgctggacccaaggacatggtggtcggcttcgcaaacctg
ggtatacttcatgtgacaaagaaaaaagtatttgaaacactggaagcacgaatgacagag
gcgtgtataaggggctataatcctggactcttggtgcaccctgaccttgcctatttgcaa
gcagaaggtggaggggaccggcagctgggagatcgggaaaaagagctaatccgccaagca
gctctgcagcagaccaaggagatggacctcagcgtggtgcggctcatgtttacagctttt
cttccggatagcactggcagcttcacaaggcgcctggaacccgtggtatcagacgccatc
tatgacagtaaagcccccaatgcatccaacttgaaaattgtaagaatggacaggacagct
ggatgtgtgactggaggggaggaaatttatcttctctgtgacaaagttcagaaagatgac
atccagattcgattttatgaagaggaagaaaatggtggagtctgggaaggatttggagat
ttttcccccacagatgttcatagacaatttgccattgtcttcaaaactccaaagtataaa
gatattaatattacaaaaccagcctctgtgtttgtccagcttcggaggaaatctgacttg
gaaactagtgaaccaaaacctttcctctactatcctgaaatcaaagataaagaagaagtg
cagaggaaacgtcagaagctcatgcccaatttttcagatagtttcggcggtggtagtggt
gccggagctggaggcggaggcatgtttggtagtggcggtggaggagggggcactggaagt
acaggtccagggtatagcttcccgcactatggatttcctacttatggtgggattactttc
catcctggaactactaaatctaatgctgggatgaagcatggaaccatggacactgaatct
aaaaaggaccctgaaggttgtgacaaaagtgatgacaaaaacactgtaaacctctttggg
aaagttattgaaaccacagagcaagatcaggagcccagcgaggccaccgttgggaatggt
gaggtcactctaacgtatgcaacaggaacaaaagaagagagtgctggggttcaggataac
ctctttctagagaaggctatgcagcttgcaaagaggcatgccaatgcccttttcgactac
gcggtgacaggagacgtgaagatgctgctggccgtccagcgccatctcactgctgtgcag
gatgagaatggggacagtgtcttacacttagcaatcatccaccttcattctcaacttgtg
agggatctactagaagtcacatctggtttgatttctgatgacattatcaacatgagaaat
gatctgtaccagacacccttgcacttggcagtgatcactaagcaggaagatgtggtggag
gatttgctgagggctggggccgacctgagccttctggaccgcttgggtaactctgttttg
cacctagctgccaaagaaggacatgataaagttctcagtgtcttactcaagcacaaaaag
gcagcactacttcttgaccaccccaacggggacggtctgaatgccattcatctagccatg
atgagcaatagcctgccatgtttgctgctgctggtggccgctggggccgacgtcaatgct
caggagcagaagtccgggcgcacagcactgcacctggctgtggagcacgacaacatctca
ttggcaggctgcctgctcctggagggtgatgcccatgtggacagtactacctacgatgga
accacacccctgcatatagcagctgggagagggtccaccaggctggcagctcttctcaaa
gcagcaggagcagatcccctggtggagaactttgagcctctctatgacctggatgactct
tgggaaaatgcaggagaggatgaaggagttgtgcctggaaccacgcctctagatatggcc
accagctggcaggtatttgacatattaaatgggaaaccatatgagccagagtttacatct
gatgatttactagcacaaggagacatgaaacagctggctgaagatgtgaagctgcagctg
tataagttactagaaattcctgatccagacaaaaactgggctactctggcgcagaaatta
ggtctggggatacttaataatgccttccggctgagtcctgctccttccaaaacacttatg
gacaactatgaggtctctgggggtacagtcagagagctggtggaggccctgagacaaatg
ggctacaccgaagcaattgaagtgatccaggcagcctccagcccagtgaagaccacctct
caggcccactcgctgcctctctcgcctgcctccacaaggcagcaaatagacgagctccga
gacagtgacagtgtctgcgacagcggcgtggagacatccttccgcaaactcagctttacc
gagtctctgaccagtggtgcctcactgctaactctcaacaaaatgccccatgattatggg
caggaaggacctctagaaggcaaaatttag

  All links  
Gene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (8)   
   Pfam (8)   
All databases (17)   

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