KEGG   Pan paniscus (bonobo): 100987483
Entry
100987483         CDS       T02283                                 
Symbol
IKBKG
Name
(RefSeq) NF-kappa-B essential modulator isoform X1
  KO
K07210  inhibitor of nuclear factor kappa-B kinase subunit gamma
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01523  Antifolate resistance
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04062  Chemokine signaling pathway
pps04064  NF-kappa B signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04210  Apoptosis
pps04380  Osteoclast differentiation
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04625  C-type lectin receptor signaling pathway
pps04657  IL-17 signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps04660  T cell receptor signaling pathway
pps04662  B cell receptor signaling pathway
pps04668  TNF signaling pathway
pps04920  Adipocytokine signaling pathway
pps04936  Alcoholic liver disease
pps05010  Alzheimer disease
pps05132  Salmonella infection
pps05135  Yersinia infection
pps05142  Chagas disease
pps05145  Toxoplasmosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05166  Human T-cell leukemia virus 1 infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05203  Viral carcinogenesis
pps05208  Chemical carcinogenesis - reactive oxygen species
pps05212  Pancreatic cancer
pps05215  Prostate cancer
pps05220  Chronic myeloid leukemia
pps05221  Acute myeloid leukemia
pps05222  Small cell lung cancer
pps05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pps05340  Primary immunodeficiency
pps05417  Lipid and atherosclerosis
pps05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100987483 (IKBKG)
   04014 Ras signaling pathway
    100987483 (IKBKG)
   04064 NF-kappa B signaling pathway
    100987483 (IKBKG)
   04668 TNF signaling pathway
    100987483 (IKBKG)
   04151 PI3K-Akt signaling pathway
    100987483 (IKBKG)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    100987483 (IKBKG)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100987483 (IKBKG)
   04621 NOD-like receptor signaling pathway
    100987483 (IKBKG)
   04622 RIG-I-like receptor signaling pathway
    100987483 (IKBKG)
   04623 Cytosolic DNA-sensing pathway
    100987483 (IKBKG)
   04625 C-type lectin receptor signaling pathway
    100987483 (IKBKG)
   04660 T cell receptor signaling pathway
    100987483 (IKBKG)
   04658 Th1 and Th2 cell differentiation
    100987483 (IKBKG)
   04659 Th17 cell differentiation
    100987483 (IKBKG)
   04657 IL-17 signaling pathway
    100987483 (IKBKG)
   04662 B cell receptor signaling pathway
    100987483 (IKBKG)
   04062 Chemokine signaling pathway
    100987483 (IKBKG)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    100987483 (IKBKG)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100987483 (IKBKG)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100987483 (IKBKG)
   05208 Chemical carcinogenesis - reactive oxygen species
    100987483 (IKBKG)
   05203 Viral carcinogenesis
    100987483 (IKBKG)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100987483 (IKBKG)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100987483 (IKBKG)
   05221 Acute myeloid leukemia
    100987483 (IKBKG)
   05220 Chronic myeloid leukemia
    100987483 (IKBKG)
   05215 Prostate cancer
    100987483 (IKBKG)
   05222 Small cell lung cancer
    100987483 (IKBKG)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100987483 (IKBKG)
   05170 Human immunodeficiency virus 1 infection
    100987483 (IKBKG)
   05161 Hepatitis B
    100987483 (IKBKG)
   05160 Hepatitis C
    100987483 (IKBKG)
   05171 Coronavirus disease - COVID-19
    100987483 (IKBKG)
   05164 Influenza A
    100987483 (IKBKG)
   05162 Measles
    100987483 (IKBKG)
   05168 Herpes simplex virus 1 infection
    100987483 (IKBKG)
   05163 Human cytomegalovirus infection
    100987483 (IKBKG)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100987483 (IKBKG)
   05169 Epstein-Barr virus infection
    100987483 (IKBKG)
   05165 Human papillomavirus infection
    100987483 (IKBKG)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100987483 (IKBKG)
   05135 Yersinia infection
    100987483 (IKBKG)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100987483 (IKBKG)
   05142 Chagas disease
    100987483 (IKBKG)
  09163 Immune disease
   05340 Primary immunodeficiency
    100987483 (IKBKG)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100987483 (IKBKG)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100987483 (IKBKG)
   05418 Fluid shear stress and atherosclerosis
    100987483 (IKBKG)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100987483 (IKBKG)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100987483 (IKBKG)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pps01001]
    100987483 (IKBKG)
Protein kinases [BR:pps01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   100987483 (IKBKG)
SSDB
Motif
Pfam: NEMO CC2-LZ zf_C2H2_10 Bacillus_HBL LLC1 Nairovirus_NSm
Other DBs
NCBI-GeneID: 100987483
NCBI-ProteinID: XP_008951069
Position
X:154521470..154539144
AA seq 419 aa
MNRHLWKSQLCEMVQPSGGPAADQDVLGEESPLGKPAMLHLPSEQGAPETLQRCLEENQE
LRDAIRQSNQMLRERCEELLHFQASQREEKEFLMCKFQEARKLVERLSLEKLDLKRQKEQ
ALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQALEGRARAASEQ
ARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVAYHQLFQE
YDNHIKSSVVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPV
LKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLKASCQESARIEDMRKRH
VEVSQAPLPPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE
NT seq 1260 nt   +upstreamnt  +downstreamnt
atgaataggcacctctggaagagccaactgtgtgagatggtgcagcccagtggtggcccg
gcagcagatcaggacgtactgggcgaagagtctcctctggggaagccagccatgctgcac
ctgccttcagaacagggcgctcctgagaccctccagcgctgcctggaggagaatcaagag
ctccgagatgccatccggcagagcaaccagatgctgcgggagcgctgcgaggagcttctg
catttccaagccagccagagggaggagaaggagtttctcatgtgcaagttccaggaggcc
aggaaactggtggagagactcagcctggagaagctcgacctgaagaggcagaaggagcag
gctctgcgggaggtggagcacctgaagagatgccagcagcagatggctgaggacaaggcc
tctgtgaaagcccaggtgacgtccttgctcggggagctgcaggagagccagagtcgcttg
gaggctgccactaaggaatgccaggctctggagggtcgggcccgggcggccagcgagcag
gcgcggcagctggagagtgagcgcgaggcgctgcagcagcagcacagcgtgcaggtggac
cagctgcgcatgcagggccagagcgtggaggccgcgctccgcatggagcgccaggccgcc
tcggaggagaagaggaagctggcccagttgcaggtggcctatcaccagctcttccaagaa
tacgacaaccacatcaagagcagcgtggtgggcagtgagcggaagcgaggaatgcagctg
gaagatctcaaacagcagctccagcaggccgaggaggccctggtggccaaacaggaggtg
atcgataagctgaaggaggaggccgagcagcacaagattgtgatggagaccgttccggtg
ctgaaggcccaggcggatatctacaaggcggacttccaggctgagaggcaggcccgggag
aagctggctgagaagaaggagctcctgcaggagcagctggagcagctgcagagggagtac
agcaaactgaaggccagctgtcaggagtcggccaggatcgaggacatgaggaagcggcat
gtcgaggtctcccaggcccccttgccccccgcccctgcctacctctcctctcccctggcc
ctgcccagccagaggaggagcccccccgaggagccacctgacttctgctgtcccaagtgc
cagtatcaggcccctgatatggacaccctgcagatacatgtcatggagtgcattgagtag

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (6)   
   RefSeq(pep) (6)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (6)   
   Pfam (6)   
All databases (21)   

Download RDF
KEGG   Pan paniscus (bonobo): 100989390
Entry
100989390         CDS       T02283                                 
Symbol
IKBKB
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
  KO
K07209  inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01523  Antifolate resistance
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04062  Chemokine signaling pathway
pps04064  NF-kappa B signaling pathway
pps04068  FoxO signaling pathway
pps04150  mTOR signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04210  Apoptosis
pps04380  Osteoclast differentiation
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04625  C-type lectin receptor signaling pathway
pps04657  IL-17 signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps04660  T cell receptor signaling pathway
pps04662  B cell receptor signaling pathway
pps04668  TNF signaling pathway
pps04722  Neurotrophin signaling pathway
pps04910  Insulin signaling pathway
pps04920  Adipocytokine signaling pathway
pps04930  Type II diabetes mellitus
pps04931  Insulin resistance
pps04932  Non-alcoholic fatty liver disease
pps04936  Alcoholic liver disease
pps05010  Alzheimer disease
pps05132  Salmonella infection
pps05135  Yersinia infection
pps05142  Chagas disease
pps05145  Toxoplasmosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05166  Human T-cell leukemia virus 1 infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05206  MicroRNAs in cancer
pps05208  Chemical carcinogenesis - reactive oxygen species
pps05212  Pancreatic cancer
pps05215  Prostate cancer
pps05220  Chronic myeloid leukemia
pps05221  Acute myeloid leukemia
pps05222  Small cell lung cancer
pps05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pps05417  Lipid and atherosclerosis
pps05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100989390 (IKBKB)
   04014 Ras signaling pathway
    100989390 (IKBKB)
   04064 NF-kappa B signaling pathway
    100989390 (IKBKB)
   04668 TNF signaling pathway
    100989390 (IKBKB)
   04068 FoxO signaling pathway
    100989390 (IKBKB)
   04151 PI3K-Akt signaling pathway
    100989390 (IKBKB)
   04150 mTOR signaling pathway
    100989390 (IKBKB)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    100989390 (IKBKB)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100989390 (IKBKB)
   04621 NOD-like receptor signaling pathway
    100989390 (IKBKB)
   04622 RIG-I-like receptor signaling pathway
    100989390 (IKBKB)
   04623 Cytosolic DNA-sensing pathway
    100989390 (IKBKB)
   04625 C-type lectin receptor signaling pathway
    100989390 (IKBKB)
   04660 T cell receptor signaling pathway
    100989390 (IKBKB)
   04658 Th1 and Th2 cell differentiation
    100989390 (IKBKB)
   04659 Th17 cell differentiation
    100989390 (IKBKB)
   04657 IL-17 signaling pathway
    100989390 (IKBKB)
   04662 B cell receptor signaling pathway
    100989390 (IKBKB)
   04062 Chemokine signaling pathway
    100989390 (IKBKB)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100989390 (IKBKB)
   04920 Adipocytokine signaling pathway
    100989390 (IKBKB)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100989390 (IKBKB)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100989390 (IKBKB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100989390 (IKBKB)
   05206 MicroRNAs in cancer
    100989390 (IKBKB)
   05208 Chemical carcinogenesis - reactive oxygen species
    100989390 (IKBKB)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100989390 (IKBKB)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100989390 (IKBKB)
   05221 Acute myeloid leukemia
    100989390 (IKBKB)
   05220 Chronic myeloid leukemia
    100989390 (IKBKB)
   05215 Prostate cancer
    100989390 (IKBKB)
   05222 Small cell lung cancer
    100989390 (IKBKB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100989390 (IKBKB)
   05170 Human immunodeficiency virus 1 infection
    100989390 (IKBKB)
   05161 Hepatitis B
    100989390 (IKBKB)
   05160 Hepatitis C
    100989390 (IKBKB)
   05171 Coronavirus disease - COVID-19
    100989390 (IKBKB)
   05164 Influenza A
    100989390 (IKBKB)
   05162 Measles
    100989390 (IKBKB)
   05168 Herpes simplex virus 1 infection
    100989390 (IKBKB)
   05163 Human cytomegalovirus infection
    100989390 (IKBKB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100989390 (IKBKB)
   05169 Epstein-Barr virus infection
    100989390 (IKBKB)
   05165 Human papillomavirus infection
    100989390 (IKBKB)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100989390 (IKBKB)
   05135 Yersinia infection
    100989390 (IKBKB)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100989390 (IKBKB)
   05142 Chagas disease
    100989390 (IKBKB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100989390 (IKBKB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100989390 (IKBKB)
   05418 Fluid shear stress and atherosclerosis
    100989390 (IKBKB)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100989390 (IKBKB)
   04936 Alcoholic liver disease
    100989390 (IKBKB)
   04932 Non-alcoholic fatty liver disease
    100989390 (IKBKB)
   04931 Insulin resistance
    100989390 (IKBKB)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100989390 (IKBKB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pps01001]
    100989390 (IKBKB)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     100989390 (IKBKB)
Protein kinases [BR:pps01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   100989390 (IKBKB)
SSDB
Motif
Pfam: IKBKB_SDD Pkinase PK_Tyr_Ser-Thr IKKbetaNEMObind Pkinase_fungal Kdo ubiquitin YrbL-PhoP_reg APH Glyco_hydro_65m
Other DBs
NCBI-GeneID: 100989390
NCBI-ProteinID: XP_008975160
Ensembl: ENSPPAG00000034251
UniProt: A0A2R9B3R9
Position
7:60723875..60784734
AA seq 760 aa
MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCL
EIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREG
AILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCT
SFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSE
VDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCF
KALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLA
LIPDKPATQCISDGKLNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRN
LAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLK
AKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMAL
QTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQS
FEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKI
ACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLE
NAIQDTVREQDQSFTVTACALDWSWLQTEEEEHSCLEQAS
NT seq 2283 nt   +upstreamnt  +downstreamnt
atgagctggtcaccttccctgacaacgcagacatgtggggcctgggaaatgaaagagcgc
cttgggacagggggatttggaaatgtcatccgatggcacaatcaggaaacaggtgagcag
attgccatcaagcagtgccggcaggagctcagcccccggaaccgagagcggtggtgcctg
gagatccagatcatgagaaggctgacccaccccaatgtggtggctgcccgagatgtccct
gaggggatgcagaacttggcgcccaatgacctgcccctgctggccatggagtactgccaa
ggaggagatctccggaagtacctgaaccagtttgagaactgctgtggtctgcgggaaggt
gccatcctcaccttgctgagtgacattgcctctgcgcttagataccttcatgaaaacaga
atcatccatcgggatctaaagccagaaaacatcgtcctgcagcaaggagaacagaggtta
atacacaaaattattgacctaggatatgccaaggagctggatcagggcagtctttgcaca
tcattcgtggggaccctgcagtacctggccccagagctactggagcagcagaagtacaca
gtgaccgtcgactactggagcttcggcaccctggcctttgagtgcatcacgggcttccgg
cccttcctccccaactggcagcctgtgcagtggcattcgaaagtgcggcagaagagtgag
gtggacattgttgttagcgaagacttgaatggaacggtgaagttttcaagctctttaccc
taccccaataatcttaacagtgtcctggctgagcgactggagaagtggctgcaactgatg
ctgatgtggcacccccgacagaggggcacggatcccacgtatgggcccaacggctgcttc
aaggccctggatgacatcttaaacttaaagctggttcatatcttgaacatggtcacgggc
accatccacacctaccctgtgacagaggatgagagtctgcagagcttgaaggccagaatc
cagcaggacacgggcatcccagaggaggaccaggagctgctgcaggaagcgggcctggcg
ttgatccccgataagcctgccactcagtgtatttcagacggcaagttaaatgagggccac
acattggacatggatcttgtttttctctttgacaacagtaaaatcacctatgagactcag
atctccccacggccccaacctgaaagtgtcagctgtatccttcaagagcccaagaggaat
ctcgccttcttccagctgaggaaggtgtggggccaggtctggcacagcatccagaccctg
aaggaagattgcaaccggctgcagcagggacagcgagccgccatgatgaatctcctccga
aacaacagctgcctctccaaaatgaagaattccatggcttccatgtctcagcagctcaag
gccaagttggatttcttcaaaaccagcatccagattgacctggagaagtacagcgagcaa
accgagtttgggatcacatcagataaactgctgctggcctggagggaaatggagcaggct
gtggagctctgtgggcgggagaacgaagtgaaactcctggtagaacggatgatggctctg
cagaccgacattgtggacttacagaggagccccatgggccggaagcaggggggaacgctg
gacgacctagaggagcaagcaagggagctgtacaggagactaagggaaaaacctcgagac
cagcgaactgagggtgacagtcaggaaatggtacggctgctgcttcaggcaattcagagc
ttcgagaagaaagtgcgagtgatctatacgcagctcagtaaaactgtggtttgcaagcag
aaggcgctggaactgttgcccaaggtggaagaggtggtgagcttaatgaatgaggatgag
aagactgttgtccggctgcaggagaagcggcagaaggagctctggaatctcctgaagatt
gcttgtagcaaggtccgtggtcctgtcagtggaagtccggatagcatgaatgcctctcga
cttagccagcctgggcagctgatgtctcagccctccacggcctccaacagcttacctgag
ccagccaagaagagtgaagaactggtggctgaagcacataacctgtgcaccctgctagaa
aatgccatacaggacaccgtgagggaacaagaccagagtttcacggtaacagcttgtgcc
ctagactggagctggttacagacggaagaagaagagcacagctgcctggagcaggcctca
tga

  All links  
Gene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   RefSeq(pep) (9)   
DNA sequence (9)   
   RefSeq(nuc) (9)   
Protein domain (10)   
   Pfam (10)   
All databases (33)   

Download RDF
KEGG   Pan paniscus (bonobo): 100995228
Entry
100995228         CDS       T02283                                 
Symbol
CHUK
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
  KO
K04467  inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01523  Antifolate resistance
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04062  Chemokine signaling pathway
pps04064  NF-kappa B signaling pathway
pps04068  FoxO signaling pathway
pps04150  mTOR signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04210  Apoptosis
pps04380  Osteoclast differentiation
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04622  RIG-I-like receptor signaling pathway
pps04623  Cytosolic DNA-sensing pathway
pps04625  C-type lectin receptor signaling pathway
pps04657  IL-17 signaling pathway
pps04658  Th1 and Th2 cell differentiation
pps04659  Th17 cell differentiation
pps04660  T cell receptor signaling pathway
pps04662  B cell receptor signaling pathway
pps04668  TNF signaling pathway
pps04920  Adipocytokine signaling pathway
pps04936  Alcoholic liver disease
pps05010  Alzheimer disease
pps05132  Salmonella infection
pps05135  Yersinia infection
pps05142  Chagas disease
pps05145  Toxoplasmosis
pps05160  Hepatitis C
pps05161  Hepatitis B
pps05162  Measles
pps05163  Human cytomegalovirus infection
pps05164  Influenza A
pps05165  Human papillomavirus infection
pps05166  Human T-cell leukemia virus 1 infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05200  Pathways in cancer
pps05208  Chemical carcinogenesis - reactive oxygen species
pps05212  Pancreatic cancer
pps05215  Prostate cancer
pps05220  Chronic myeloid leukemia
pps05221  Acute myeloid leukemia
pps05222  Small cell lung cancer
pps05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pps05417  Lipid and atherosclerosis
pps05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100995228 (CHUK)
   04014 Ras signaling pathway
    100995228 (CHUK)
   04064 NF-kappa B signaling pathway
    100995228 (CHUK)
   04668 TNF signaling pathway
    100995228 (CHUK)
   04068 FoxO signaling pathway
    100995228 (CHUK)
   04151 PI3K-Akt signaling pathway
    100995228 (CHUK)
   04150 mTOR signaling pathway
    100995228 (CHUK)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    100995228 (CHUK)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100995228 (CHUK)
   04621 NOD-like receptor signaling pathway
    100995228 (CHUK)
   04622 RIG-I-like receptor signaling pathway
    100995228 (CHUK)
   04623 Cytosolic DNA-sensing pathway
    100995228 (CHUK)
   04625 C-type lectin receptor signaling pathway
    100995228 (CHUK)
   04660 T cell receptor signaling pathway
    100995228 (CHUK)
   04658 Th1 and Th2 cell differentiation
    100995228 (CHUK)
   04659 Th17 cell differentiation
    100995228 (CHUK)
   04657 IL-17 signaling pathway
    100995228 (CHUK)
   04662 B cell receptor signaling pathway
    100995228 (CHUK)
   04062 Chemokine signaling pathway
    100995228 (CHUK)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    100995228 (CHUK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100995228 (CHUK)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100995228 (CHUK)
   05208 Chemical carcinogenesis - reactive oxygen species
    100995228 (CHUK)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100995228 (CHUK)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100995228 (CHUK)
   05221 Acute myeloid leukemia
    100995228 (CHUK)
   05220 Chronic myeloid leukemia
    100995228 (CHUK)
   05215 Prostate cancer
    100995228 (CHUK)
   05222 Small cell lung cancer
    100995228 (CHUK)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100995228 (CHUK)
   05170 Human immunodeficiency virus 1 infection
    100995228 (CHUK)
   05161 Hepatitis B
    100995228 (CHUK)
   05160 Hepatitis C
    100995228 (CHUK)
   05171 Coronavirus disease - COVID-19
    100995228 (CHUK)
   05164 Influenza A
    100995228 (CHUK)
   05162 Measles
    100995228 (CHUK)
   05168 Herpes simplex virus 1 infection
    100995228 (CHUK)
   05163 Human cytomegalovirus infection
    100995228 (CHUK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100995228 (CHUK)
   05169 Epstein-Barr virus infection
    100995228 (CHUK)
   05165 Human papillomavirus infection
    100995228 (CHUK)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100995228 (CHUK)
   05135 Yersinia infection
    100995228 (CHUK)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100995228 (CHUK)
   05142 Chagas disease
    100995228 (CHUK)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100995228 (CHUK)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100995228 (CHUK)
   05418 Fluid shear stress and atherosclerosis
    100995228 (CHUK)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100995228 (CHUK)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100995228 (CHUK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pps01001]
    100995228 (CHUK)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     100995228 (CHUK)
Protein kinases [BR:pps01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   100995228 (CHUK)
SSDB
Motif
Pfam: IKBKB_SDD Pkinase PK_Tyr_Ser-Thr IKKbetaNEMObind Pkinase_fungal Kdo TBK1_ULD
Other DBs
NCBI-GeneID: 100995228
NCBI-ProteinID: XP_003825511
Ensembl: ENSPPAG00000037851
Position
8:complement(112077682..112118610)
AA seq 745 aa
MERPPGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCH
EIQIMKKLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQ
ILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIIHKIIDLGYAKDVDQGSLCTS
FVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPK
CIFACEEMSGEVRFSSHLPQPNSLCSLIVEPMENWLQLMLNWDPQQRGGPVDLTLKQPRC
FVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQELLSETGI
SLDPRKPASQCVLDGVRGCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPI
IQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKL
EFFHKSIQLDLERYSEQMTYGISSEKMLKAWKEMEEKAIHYAEVGVIGYLEDQIMSLHAE
IMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPSDHSYSDSTEMVKIIVHTVQSQDRV
LKELFGHLSKLLGCKQKIIDLLPKVEVALSNIKEADNTVMFMQGKRQKEIWHLLKIACTQ
SSARSLVGSSLEGAVTPQTSAWLPPTSAEHDHSLSCVVTPQDGETSAQMIEENLNCLGHL
STIIHEANEEQGSSMMNLDWSWLTE
NT seq 2238 nt   +upstreamnt  +downstreamnt
atggagcggcccccggggctgcggccgggcgcgggcgggccctgggagatgcgggagcgg
ctgggcaccggcggcttcgggaacgtctgtctgtaccagcatcgggaacttgatctcaaa
atagcaattaagtcttgtcgcctagagctaagtaccaaaaacagagaacgatggtgccat
gaaatccagattatgaagaagttgaatcatgccaatgttgtaaaggcctgtgatgttcct
gaagaattgaatattttgattcatgatgtgcctcttctagcaatggaatactgttctgga
ggagatctccgaaagctgctcaacaaaccagaaaattgttgtggacttaaagaaagccag
atactttctttactaagtgatatagggtctgggattcgatatttgcatgaaaacaaaatt
atacatcgagatctaaaacctgaaaacatagttcttcaggatgttggtggaaagataata
cataaaataattgatctgggatatgccaaagatgttgatcaaggaagtctgtgtacatct
tttgtgggaacactgcagtatctggccccagagctctttgagaataagccttacacagcc
actgttgattattggagctttgggaccatggtatttgaatgtattgctggatataggcct
tttttgcatcatctgcagccatttacctggcatgagaagattaagaagaaggatccaaag
tgtatatttgcatgtgaagagatgtcaggagaagttcggtttagtagccatttacctcaa
ccaaatagcctttgtagtttaatagtagaacccatggaaaactggctacagttgatgttg
aattgggaccctcagcagagaggaggacccgttgaccttactttgaagcagccaagatgt
ttcgtattaatggatcacattttgaatttgaagatagtacacatcctaaatatgacttct
gcaaagataatttcttttctgttaccacctgatgaaagtcttcattcactacagtctcgt
attgagcgtgaaactggaataaatactggttctcaagaacttctttcagagacaggaatt
tctctggatcctcggaaaccagcctctcaatgtgttctagatggagttagaggctgtgat
agctatatggtttatttgtttgataaaagtaaaactgtatatgaagggccatttgcttcc
agaagcttatctgattgtgtaaattatattgtacaggacagcaaaatacagcttccaatt
atacagctgcgtaaagtgtgggctgaagcagtgcactatgtgtctggactaaaagaagac
tatagcaggctctttcagggacaaagggcagcaatgttaagtcttcttagatataatgct
aacttaacaaaaatgaagaacactttgatctcagcatcacaacaactgaaagctaaattg
gagttttttcacaaaagcattcagcttgacttggagagatacagcgagcagatgacgtat
gggatatcttcagaaaaaatgctaaaagcatggaaagaaatggaagaaaaggccatccac
tatgctgaggttggtgtcattggatatctggaggatcagattatgtctttgcatgctgaa
atcatggagctacagaagagcccctatggaagacgtcagggagacttgatggaatctctg
gaacagcgtgccattgatctatataagcagttaaaacacagaccttcagatcactcctac
agtgacagcacagagatggtgaaaatcattgtgcacactgtgcagagtcaggaccgtgtg
ctcaaggagctgtttggtcatttgagcaagttgttgggctgtaagcagaagattattgat
ctactccctaaggtggaagtggccctcagtaatatcaaagaagctgacaatactgtcatg
ttcatgcagggaaaaaggcagaaagaaatatggcatctccttaaaattgcctgtacacag
agttctgcccggtcccttgtaggatccagtctagaaggtgcagtaacccctcagacatca
gcatggctgcccccgacttcagcagaacatgatcattctctgtcatgtgtggtaactcct
caagatggagagacttcagcacaaatgatagaagaaaatttgaactgccttggccattta
agcactattattcatgaggcaaatgaggaacagggcagtagtatgatgaatcttgattgg
agttggttaacagaatga

  All links  
Gene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (7)   
   Pfam (7)   
All databases (17)   

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