KEGG   Pan paniscus (bonobo): 100990286
Entry
100990286         CDS       T02283                                 

Gene name
PTPN6
Definition
(RefSeq) protein tyrosine phosphatase, non-receptor type 6
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04520  Adherens junction
pps04630  JAK-STAT signaling pathway
pps04650  Natural killer cell mediated cytotoxicity
pps04660  T cell receptor signaling pathway
pps04662  B cell receptor signaling pathway
pps05140  Leishmaniasis
pps05205  Proteoglycans in cancer
pps05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100990286 (PTPN6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    100990286 (PTPN6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100990286 (PTPN6)
   04660 T cell receptor signaling pathway
    100990286 (PTPN6)
   04662 B cell receptor signaling pathway
    100990286 (PTPN6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100990286 (PTPN6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100990286 (PTPN6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    100990286 (PTPN6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pps01009]
    100990286 (PTPN6)
Enzymes [BR:pps01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     100990286 (PTPN6)
Protein phosphatases and associated proteins [BR:pps01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    100990286 (PTPN6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc Y_phosphatase3 PTPlike_phytase
Other DBs
NCBI-GeneID: 100990286
NCBI-ProteinID: XP_003820304
UniProt: A0A2R8ZVQ8
Position
12
AA seq 595 aa
MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDF
YDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQA
ETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTVGG
LETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTA
KAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSD
YINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNK
CVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDH
GVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDC
DIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGNIT
YPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLKRK
NT seq 1788 nt   +upstreamnt  +downstreamnt
atggtgaggtggtttcaccgagacctcagtgggctggatgcagagaccctgctcaagggc
cgaggtgtccacggtagcttcctggctcggcccagtcgcaagaaccagggtgacttctcg
ctctccgtcagggtgggggatcaggtgacccatattcggatccagaactcaggggatttc
tatgacctgtatggaggggagaagttcgcgactctgacagagctggtggagtactacact
cagcagcagggcgtcctgcaggaccgcgacggcaccatcatccacctcaagtacccgctg
aactgctccgatcccactagtgagaggtggtaccatggccacatgtctggcgggcaggca
gagacgctgctgcaggctaagggcgagccctggacgtttcttgtgcgtgagagcctcagc
cagcctggagacttcgtgctgtctgtgctcagtgaccagcccaaggctggcccaggctcc
ccgctcagggtcacccacatcaaggtcatgtgcgagggtggacgctacacagtgggtggt
ttggagaccttcgacagcctcacggacctggtggagcatttcaagaagacggggattgag
gaggcctcaggcgcctttgtctacctgcggcagccgtactacgccacgagggtgaatgcg
gctgacattgagaaccgagtattggaactgaacaagaagcaggagtccgaggatacagcc
aaggctggcttctgggaggagtttgagagtttgcagaagcaggaggtgaagaacttgcac
cagcgtctggaagggcagcggccagagaacaagggcaagaaccgctacaagaacattctc
ccctttgaccacagccgagtgatcctgcagggacgggacagtaacatccccgggtccgac
tacatcaatgccaactacatcaagaaccagctgctaggccctgatgagaacgctaagacc
tacatcgccagccagggctgtctggaggccacggtcaatgacttctggcagatggcgtgg
caggagaacagccgtgtcatcgtcatgaccacccgagaggtggagaaaggccggaacaaa
tgcgtcccatactggcccgaggtgggcatgcagcgtgcttatgggccctactctgtgacc
aactgcggggagcatgacacaaccgaatacaaactccgtaccttacaggtctccccgctg
gacaatggagacctgattcgggagatctggcattaccagtacctgagctggcccgaccat
ggggtccccagtgagcctgggggtgtcctcagcttcctggaccagatcaaccagcggcag
gaaagtctgcctcacgcagggcccatcatcgtgcactgcagcgccggcatcggccgcaca
ggcaccatcattgtcatcgacatgctcatggagaacatctccaccaagggcctggactgt
gacattgacatccagaagaccatccagatggtgcgggcgcagcgctcgggcatggtgcag
acggaggcgcagtacaagttcatctacgtggccatcgcccagttcattgaaaccactaag
aagaagctggaggtcctgcagtcacagaagggccaggagtcggagtacgggaacatcacc
taccccccagccatgaagaatgcccatgccaaggcctcccgcacctcgtccaaacacaag
gaggatgtgtatgagaacctgcacactaagaacaagagggaggagaaagtgaagaagcag
cggtcagcagacaaggagaagagcaagggttccctcaagaggaagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (5)   
   Pfam (5)   
All databases (29)   

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