KEGG   Pan troglodytes (chimpanzee): 473983
Entry
473983            CDS       T01005                                 
Symbol
CBR1
Name
(RefSeq) carbonyl reductase [NADPH] 1 isoform X2
  KO
K00079  carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr00590  Arachidonic acid metabolism
ptr00790  Folate biosynthesis
ptr00980  Metabolism of xenobiotics by cytochrome P450
ptr01100  Metabolic pathways
ptr05204  Chemical carcinogenesis - DNA adducts
ptr05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    473983 (CBR1)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    473983 (CBR1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    473983 (CBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    473983 (CBR1)
   05208 Chemical carcinogenesis - reactive oxygen species
    473983 (CBR1)
Enzymes [BR:ptr01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.184  carbonyl reductase (NADPH)
     473983 (CBR1)
    1.1.1.189  prostaglandin-E2 9-reductase
     473983 (CBR1)
    1.1.1.197  15-hydroxyprostaglandin dehydrogenase (NADP+)
     473983 (CBR1)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR
Other DBs
NCBI-GeneID: 473983
NCBI-ProteinID: XP_009457585
Ensembl: ENSPTRG00000013886
VGNC: 14651
UniProt: A0A2J8M7L4
Position
21:22643988..22647272
AA seq 222 aa
MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFH
QLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRD
VCTELLPLIKPQVVLLLRLWFTRTSKGSSSKSHLTLLSQNSKAGMNFFMQLPPHFLCVFL
LELIPVTVSHMKIFCSKIPANLAFTSLRDCCTPFYIMLCGVS
NT seq 669 nt   +upstreamnt  +downstreamnt
atgtcgtccggcatccatgtagcgctggtgactggcggcaacaagggcatcggcttggcc
atcgtgcgcgacctgtgccggctgttctcgggggacgtggtgctcacggcgcgggacgtg
acgcggggccaggcagccgtacagcaactgcaggcggagggcctgagcccgcgcttccac
cagctggacatcgacgatctgcagagcatccgcgccctgcgcgacttcctgcgcaaggag
tacgggggcctggacgtgctggtcaacaacgcgggcatcgccttcaaggttgctgatccc
acaccctttcatattcaagctgaagtgacgatgaaaacaaacttctttggtacccgggat
gtgtgcacagaattactccctctaataaaaccccaagttgtgctacttctaaggctctgg
ttcaccaggacctcaaagggcagctcttccaaatctcacctgactctactcagccaaaat
tcgaaggcaggaatgaacttcttcatgcaactaccaccacactttctatgcgtattcctc
ttagaactcataccagtaactgtctctcatatgaaaattttctgctccaaaatccctgca
aatttggcattcacctctctacgggattgttgcacacctttctacataatgctttgtggt
gtatcttag

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