KEGG   Rousettus aegyptiacus (Egyptian rousette): 107518038
Entry
107518038         CDS       T06036                                 
Symbol
ADCY5
Name
(RefSeq) LOW QUALITY PROTEIN: adenylate cyclase type 5
  KO
K08045  adenylate cyclase 5 [EC:4.6.1.1]
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00230  Purine metabolism
ray01100  Metabolic pathways
ray01522  Endocrine resistance
ray04015  Rap1 signaling pathway
ray04022  cGMP-PKG signaling pathway
ray04024  cAMP signaling pathway
ray04062  Chemokine signaling pathway
ray04072  Phospholipase D signaling pathway
ray04114  Oocyte meiosis
ray04211  Longevity regulating pathway
ray04213  Longevity regulating pathway - multiple species
ray04261  Adrenergic signaling in cardiomyocytes
ray04270  Vascular smooth muscle contraction
ray04371  Apelin signaling pathway
ray04540  Gap junction
ray04611  Platelet activation
ray04713  Circadian entrainment
ray04714  Thermogenesis
ray04723  Retrograde endocannabinoid signaling
ray04724  Glutamatergic synapse
ray04725  Cholinergic synapse
ray04726  Serotonergic synapse
ray04727  GABAergic synapse
ray04728  Dopaminergic synapse
ray04750  Inflammatory mediator regulation of TRP channels
ray04911  Insulin secretion
ray04912  GnRH signaling pathway
ray04913  Ovarian steroidogenesis
ray04914  Progesterone-mediated oocyte maturation
ray04915  Estrogen signaling pathway
ray04916  Melanogenesis
ray04918  Thyroid hormone synthesis
ray04921  Oxytocin signaling pathway
ray04923  Regulation of lipolysis in adipocytes
ray04924  Renin secretion
ray04925  Aldosterone synthesis and secretion
ray04926  Relaxin signaling pathway
ray04927  Cortisol synthesis and secretion
ray04928  Parathyroid hormone synthesis, secretion and action
ray04934  Cushing syndrome
ray04935  Growth hormone synthesis, secretion and action
ray04970  Salivary secretion
ray04971  Gastric acid secretion
ray04972  Pancreatic secretion
ray04976  Bile secretion
ray05012  Parkinson disease
ray05030  Cocaine addiction
ray05031  Amphetamine addiction
ray05032  Morphine addiction
ray05034  Alcoholism
ray05163  Human cytomegalovirus infection
ray05166  Human T-cell leukemia virus 1 infection
ray05200  Pathways in cancer
ray05207  Chemical carcinogenesis - receptor activation
ray05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ray00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    107518038 (ADCY5)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    107518038 (ADCY5)
   04371 Apelin signaling pathway
    107518038 (ADCY5)
   04072 Phospholipase D signaling pathway
    107518038 (ADCY5)
   04024 cAMP signaling pathway
    107518038 (ADCY5)
   04022 cGMP-PKG signaling pathway
    107518038 (ADCY5)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    107518038 (ADCY5)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    107518038 (ADCY5)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    107518038 (ADCY5)
   04062 Chemokine signaling pathway
    107518038 (ADCY5)
  09152 Endocrine system
   04911 Insulin secretion
    107518038 (ADCY5)
   04923 Regulation of lipolysis in adipocytes
    107518038 (ADCY5)
   04912 GnRH signaling pathway
    107518038 (ADCY5)
   04913 Ovarian steroidogenesis
    107518038 (ADCY5)
   04915 Estrogen signaling pathway
    107518038 (ADCY5)
   04914 Progesterone-mediated oocyte maturation
    107518038 (ADCY5)
   04921 Oxytocin signaling pathway
    107518038 (ADCY5)
   04926 Relaxin signaling pathway
    107518038 (ADCY5)
   04935 Growth hormone synthesis, secretion and action
    107518038 (ADCY5)
   04918 Thyroid hormone synthesis
    107518038 (ADCY5)
   04928 Parathyroid hormone synthesis, secretion and action
    107518038 (ADCY5)
   04916 Melanogenesis
    107518038 (ADCY5)
   04924 Renin secretion
    107518038 (ADCY5)
   04925 Aldosterone synthesis and secretion
    107518038 (ADCY5)
   04927 Cortisol synthesis and secretion
    107518038 (ADCY5)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    107518038 (ADCY5)
   04270 Vascular smooth muscle contraction
    107518038 (ADCY5)
  09154 Digestive system
   04970 Salivary secretion
    107518038 (ADCY5)
   04971 Gastric acid secretion
    107518038 (ADCY5)
   04972 Pancreatic secretion
    107518038 (ADCY5)
   04976 Bile secretion
    107518038 (ADCY5)
  09156 Nervous system
   04724 Glutamatergic synapse
    107518038 (ADCY5)
   04727 GABAergic synapse
    107518038 (ADCY5)
   04725 Cholinergic synapse
    107518038 (ADCY5)
   04728 Dopaminergic synapse
    107518038 (ADCY5)
   04726 Serotonergic synapse
    107518038 (ADCY5)
   04723 Retrograde endocannabinoid signaling
    107518038 (ADCY5)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    107518038 (ADCY5)
  09149 Aging
   04211 Longevity regulating pathway
    107518038 (ADCY5)
   04213 Longevity regulating pathway - multiple species
    107518038 (ADCY5)
  09159 Environmental adaptation
   04713 Circadian entrainment
    107518038 (ADCY5)
   04714 Thermogenesis
    107518038 (ADCY5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107518038 (ADCY5)
   05207 Chemical carcinogenesis - receptor activation
    107518038 (ADCY5)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    107518038 (ADCY5)
   05163 Human cytomegalovirus infection
    107518038 (ADCY5)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    107518038 (ADCY5)
  09165 Substance dependence
   05030 Cocaine addiction
    107518038 (ADCY5)
   05031 Amphetamine addiction
    107518038 (ADCY5)
   05032 Morphine addiction
    107518038 (ADCY5)
   05034 Alcoholism
    107518038 (ADCY5)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    107518038 (ADCY5)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    107518038 (ADCY5)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    107518038 (ADCY5)
Enzymes [BR:ray01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     107518038 (ADCY5)
SSDB
Motif
Pfam: AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD PEN-2 HILPDA GBR2_CC
Other DBs
NCBI-GeneID: 107518038
NCBI-ProteinID: XP_016014846
Position
Unknown
AA seq 1259 aa
MSGSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADARANGYPHAPGGSARGSTKRPGGA
VTPQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR
GAAGGGSTRAPPAGGGGGSAAAAAAAGGTEVRPRSVELGLEERRGKGRXVDELEAGAVEG
DGGSADGGSLAGSGAGPGPVLSLGSCCLALLQIFRSKKFPSDKLERLYQRYFFRLNQSSL
TMLMAVLVLVCLVMLAFHAARPPLQLPYLVVLAAAVGVILVMAVLCNRAAFHQDHMGLAC
YALIAVVLVVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHL
AIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQ
RENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLA
SQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGM
DMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAG
RIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQ
RTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFLGR
AIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITI
VPHSVFMLSFYLTCFVLLTLVIFVSVIYSCVKLFPAPLQTLSKKIVRSKVNSTLVGVFTI
TLVFLAAFVNMFMCNSKDLFGCLADEHNVSTSQINACHVVESAFNYSLGDEQGFCGSPWP
NCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLVVEVPGVTLFDNADLLV
TANAIDFNNNGTSQCPEHATKVALKVVTPIVISVFVLALYLHAQQVESTARLDFLWKLQA
TEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSE
FYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDK
VGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNT
VNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
NT seq 3780 nt   +upstreamnt  +downstreamnt
atgtccggctccaaaagcgtgagccccccgggctacgcggcgcagacagcggcggcgcca
gcgtcccggggaggcccggaacaccgctccgcgtggggagaggcagatgcccgcgccaat
ggctacccccacgcccccggcggttcggcccgcggctccaccaagagacccgggggggcg
gtgaccccgcagcagcagcagcgcctggccagccgctggcgcagcgacgacgacgacgac
cctccgctgagtggcgacgaccccctggccgggggctttggcttcagcttccgctctaag
tcagcctggcaggagcgcggcggcgacgactgcggacgcggcagccgccggcagcggcgg
ggcgcagctggcgggggcagcacccgggcgccccctgcgggcggcggtggcggctcggcg
gccgcggcggccgcagccggcgggaccgaggtgcgcccccgctcggtggagctgggcctg
gaggagcggcggggcaagggccgcngggtcgacgagctggaggccggcgccgtcgagggc
gacgggggctccgcggatggcggcagcttggcgggctcgggcgcgggccccggcccggtg
ctgtctctgggctcctgctgcctcgcactgctgcagatattccgctccaagaagttcccg
tcggacaagctggagcggctgtaccagcgctacttcttccgcctgaaccagagcagcctg
accatgctcatggccgtgctagtgctcgtgtgcctcgtcatgctggccttccacgcggcg
cggcccccgctccagctgccctacctggtggtgctggcggccgccgtgggcgtgatcctt
gtcatggccgtgctctgcaaccgcgccgcctttcaccaggaccacatgggcctggcctgc
tacgcgctcatcgcggtggtgctggtcgtccaggtggtgggcctgctgctgccccagcca
cgaagcgcctccgagggcatctggtggacggtgttcttcatctacaccatctacacgctg
ctacccgtgcgcatgcgggccgcagtactcagcggggtgctcctgtctgccctccacctg
gccatcgccctgcgaaccaacgcccaggaccagttcctgctcaaacagctggtctccaat
gtcctcatcttctcctgcaccaacatcgtgggtgtctgcacccactacccggcagaggtc
tcccagagacaggcgttccaggagacccgggagtgtatccaggcacggctccactcacag
cgggagaaccagcagcaggagcggctcctgctgtctgtccttccccgtcatgttgccatg
gagatgaaagcagacatcaacgccaagcaggaggatatgatgttccataagatttacatc
cagaaacatgacaatgtgagcatcctgtttgctgacatcgagggcttcaccagcttggcg
tcccagtgcacggcccaagagctggtcatgaccctcaacgagctcttcgcccgcttcgac
aagctggctgcggagaatcactgtttacgtattaagatcctgggggattgttattactgt
gtctcggggctgcctgaagcgagggccgaccacgcccactgctgcgtggagatgggcatg
gacatgattgaggccatctcgttggtccgggaggtgacaggggtgaacgtgaacatgcgc
gtgggaattcacagcgggcgagtacactgcggtgtccttggtctcaggaagtggcagttc
gacgtctggtctaacgacgtcacgctggccaaccacatggaggctggaggcaaggctgga
cgcatccacatcaccaaggccacactcaactacctgaatggagactacgaagtggagccc
ggctgtgggggcgagcgcaacgcctacctcaaggagcacagcatcgagaccttcctcatc
ctgcgctgcacccagaagcggaaagaagagaaggccatgatcgccaagatgaatcgccag
agaaccaactccatagggcacaacccgccgcactggggggctgagcgccccttctacaac
cacttgggtggcaaccaggtgtctaaggagatgaagcggatgggtttcgaagaccccaag
gacaagaatgcccaggaaagcgcgaaccccgaggacgaagtggatgaattcctgggccga
gccatcgatgccaggagtattgacaggctgcggtctgagcatgttcgcaagttcctcttg
accttcagggagcctgacttagagaagaagtactccaagcaggtggatgaccgattcggt
gcctatgtggcatgtgcctcgcttgtcttcctcttcatttgctttgtccagatcaccatc
gtgccccactccgtgttcatgttgagtttctacctgacctgtttcgtgctgctgaccttg
gtgatatttgtgtccgtcatctactcctgtgtgaagctcttccctgccccgctgcagacc
ctctccaagaagatcgtgcggtccaaggtgaacagcaccctggttggggtgttcaccatc
accctggtgttcctggcagcgtttgtcaacatgttcatgtgcaactccaaggacctgttc
ggctgcctggcagatgagcacaacgtcagcaccagccagatcaacgcttgccacgtggtg
gagtcggccttcaactacagcctgggtgacgagcagggattctgcggcagcccctggccc
aactgcaacttccctgagtacttcacctacagcgtgctgctcagcctgctggcctgctcc
gtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggccatcgagctcata
tatgtgctcgtcgtcgaagtgcccggtgtcacactctttgacaatgcagacctgctagtc
accgccaacgccatagacttcaacaacaacgggacctcccagtgccctgagcacgcgacc
aaagtggcgctgaaggtggtgacgcccattgtcatctcagtctttgtgctggccctgtac
ctgcacgcccagcaggtggagtccaccgcccgcctcgacttcctctggaaactacaggcc
acggaggagaaggaggagatggaggagctgcaggcctacaaccggcggctgctgcacaac
atcctgcccaaggacgtggccgcccacttcctggcccgggagcggcgcaacgacgagctg
tactatcagtcgtgtgagtgtgtggccgtcatgttcgcctccatcgccaacttctccgag
ttctacgtggagctggaggccaacaacgagggtgtcgagtgcctgcggctgcttaatgaa
atcattgccgatttcgacgagatcatcagcgaggatcggttcaggcagctggaaaagatc
aagaccattggcagcacctacatggctgcctcaggcctcaatgattccacctatgacaag
gtgggcaagacccacatcaaggctctggccgacttcgccatgaagctgatggaccagatg
aagtacatcaacgagcactccttcaacaacttccagatgaagattgggctcaacattggc
cccgtggtggccggggtgatcggggcccgcaagcctcagtacgacatctggggcaatacg
gtgaacgtggccagccgcatggacagcaccggtgtgcctgaccgcatccaggtcaccaca
gacatgtatcaggtgctggctgccaacacataccagctggagtgccggggtgtggtcaag
gtcaagggcaaaggagagatgatgacctacttcctcaacggagggcccccgctcagttag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (55)   
   KEGG PATHWAY (55)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (80)   

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