KEGG   REACTION: R00102
Entry
R00102                      Reaction                               
Name
NAD+ glycohydrolase
Definition
NAD+ + H2O <=> Nicotinamide + ADP-ribose
Equation
Reaction class
RC00033  C00003_C00153
RC00485  C00003_C00301
Enzyme
3.2.2.5         3.2.2.6         3.5.1.-
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
Orthology
K01242  ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
K18152  ADP-ribosyl cyclase 2 [EC:3.2.2.6 2.4.99.20]
K18153  NAD+ glycohydrolase [EC:3.2.2.5]
K19980  ADP-ribosyltransferase 2 / NAD+ glycohydrolase [EC:2.4.2.31 3.2.2.5]
Reference
1  [PMID:19001417]
  Authors
Belenky P, Christensen KC, Gazzaniga F, Pletnev AA, Brenner C.
  Title
Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+  metabolism.
  Journal
J Biol Chem 284:158-64 (2009)
DOI:10.1074/jbc.M807976200
Other DBs
RHEA: 16304

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