KEGG   REACTION: R00245
Entry
R00245                      Reaction                               
Name
L-glutamate gamma-semialdehyde:NAD+ oxidoreductase
Definition
L-Glutamate 5-semialdehyde + NAD+ + H2O <=> L-Glutamate + NADH + H+
Equation
C01165 + C00003 + C00001 <=> C00025 + C00004 + C00080
Comment
the second step of two-step reaction (see R00707, R03314+R00245)
following after R03314
Reaction class
RC00001  C00003_C00004
RC00080  C00025_C01165
Enzyme
1.2.1.88
Pathway
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Module
M00970  Proline degradation, proline => glutamate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.88
     R00245  L-Glutamate 5-semialdehyde + NAD+ + H2O <=> L-Glutamate + NADH + H+
Orthology
K00294  1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
Other DBs
RHEA: 30238

  All links  
Chemical reaction (1)   
   SABIO-RK (1)   
All databases (1)   

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