KEGG   REACTION: R01286
Entry
R01286                      Reaction                               
Name
L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming)
Definition
L-Cystathionine + H2O <=> L-Homocysteine + Ammonia + Pyruvate
Equation
C02291 + C00001 <=> C00155 + C00014 + C00022
Reaction class
RC00069  C00155_C02291
RC00488  C00022_C02291
Enzyme
4.4.1.13
Pathway
rn00270  Cysteine and methionine metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01230  Biosynthesis of amino acids
Module
M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.4  Carbon-sulfur lyases
   4.4.1  Carbon-sulfur lyases (only sub-subclass identified to date)
    4.4.1.13
     R01286  L-Cystathionine + H2O <=> L-Homocysteine + Ammonia + Pyruvate
IUBMB reaction hierarchy [BR:br08202]
 4. Lyase reactions
  4.4.1.13
   R12188  L-Cysteine-S-conjugate <=> Thiol
    R01286  L-Cystathionine <=> L-Homocysteine
Orthology
K00816  kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64]
K01760  cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
K14155  cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
Other DBs
RHEA: 13968

  All links  
Chemical reaction (1)   
   SABIO-RK (1)   
All databases (1)   

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