KEGG   REACTION: R02323
Entry
R02323                      Reaction                               
Name
nicotinamide ribonucleotide phosphohydrolase
Definition
Nicotinamide D-ribonucleotide + H2O <=> Nicotinamide-beta-riboside + Orthophosphate
Equation
C00455 + C00001 <=> C03150 + C00009
Reaction class
RC00017  C00455_C03150
Enzyme
3.1.3.5         3.1.3.-
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
Orthology
K01081  5'-nucleotidase [EC:3.1.3.5]
K02566  5'-nucleotidase [EC:3.1.3.5]
K03787  5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
K08693  2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase [EC:3.1.4.16 3.1.3.6 3.1.3.5]
K11751  5'-nucleotidase / UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45]
K18550  IMP and pyridine-specific 5'-nucleotidase [EC:3.1.3.99 3.1.3.-]
K18551  pyrimidine and pyridine-specific 5'-nucleotidase [EC:3.1.3.-]
K19970  5'-nucleotidase [EC:3.1.3.5]
Reference
1  [PMID:19846558]
  Authors
Bogan KL, Evans C, Belenky P, Song P, Burant CF, Kennedy R, Brenner C
  Title
Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside.
  Journal
J Biol Chem 284:34861-9 (2009)
DOI:10.1074/jbc.M109.056689
Other DBs
RHEA: 30818

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (17489)   
   KEGG ORTHOLOGY (8)   
   KEGG GENES (17481)   
All databases (17501)   

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