KEGG   REACTION: R02841
Entry
R02841                      Reaction                               
Name
11beta,17alpha,21-trihydroxy-5beta-pregnane-3,20-dione:NADP+ delta4-oxidoreductase;
3-oxo-5beta-steroid:NADP+ delta4-oxidoreductase
Definition
Dihydrocortisol + NADP+ <=> Cortisol + NADPH + H+
Equation
C05471 + C00006 <=> C00735 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC00145  C00735_C05471
Enzyme
1.3.1.3
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.3
     R02841  Dihydrocortisol + NADP+ <=> Cortisol + NADPH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.3.1.3
   R13168  3-Oxo-5beta-steroid <=> 3-Oxo-Delta4-steroid
    R02841  Dihydrocortisol <=> Cortisol
Orthology
K00251  3-oxo-5-beta-steroid 4-dehydrogenase [EC:1.3.1.3]

  All links  
Chemical reaction (1)   
   SABIO-RK (1)   
All databases (1)   

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