KEGG   REACTION: R03629
Entry
R03629                      Reaction                               
Name
melatonin,NADPH---hemoprotein reductase:oxygen oxidoreductase
Definition
Melatonin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6-Hydroxymelatonin + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C01598 + C03024 + C00007 <=> C05643 + C03161 + C00001
Comment
see R04122
Reaction class
RC00046  C01598_C05643
Enzyme
1.14.14.1
Pathway
rn00380  Tryptophan metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1
     R03629  Melatonin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6-Hydroxymelatonin + [Oxidized NADPH---hemoprotein reductase] + H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.1
   R04122  Alkane <=> ROH
    R03629  Melatonin <=> 6-Hydroxymelatonin
Orthology
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07409  cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K07410  cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K14338  cytochrome P450 / NADPH-cytochrome P450 reductase [EC:1.14.14.1 1.6.2.4]

  All links  
Chemical reaction (1)   
   SABIO-RK (1)   
All databases (1)   

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