KEGG   REACTION: R03869
Entry
R03869                      Reaction                               
Name
(S)-methylmalonate semialdehyde:NAD+ oxidoreductase
Definition
(S)-Methylmalonate semialdehyde + NAD+ + H2O <=> Methylmalonate + NADH + H+
Equation
C06002 + C00003 + C00001 <=> C02170 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00242  C02170_C06002
Enzyme
1.2.1.3
Pathway
rn00280  Valine, leucine and isoleucine degradation
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.3
     R03869  (S)-Methylmalonate semialdehyde + NAD+ + H2O <=> Methylmalonate + NADH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.2.1.3
   R00538  Aldehyde <=> Carboxylate
    R03869  (S)-Methylmalonate semialdehyde <=> Methylmalonate
Orthology
K00128  aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00149  aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]
K14085  aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Other DBs
RHEA: 31046

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