KEGG   REACTION: R04617
Entry
R04617                      Reaction                               
Name
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate:D-alanyl-D-alanine ligase (ADP-forming)
Definition
ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate + D-Alanyl-D-alanine <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine
Equation
C00002 + C04877 + C00993 <=> C00008 + C00009 + C04882
Reaction class
RC00002  C00002_C00008
RC00064  C00993_C04882
RC00141  C04877_C04882
Enzyme
6.3.2.10
Pathway
rn00300  Lysine biosynthesis
rn00550  Peptidoglycan biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10
     R04617  ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate + D-Alanyl-D-alanine <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine
Orthology
K01798  Alr-MurF fusion protein [EC:5.1.1.1 6.3.2.10]
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
K15792  MurE/MurF fusion protein [EC:6.3.2.13 6.3.2.10]
Other DBs
RHEA: 28377

  All links  
Chemical reaction (1)   
   SABIO-RK (1)   
All databases (1)   

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