KEGG   REACTION: R04819
Entry
R04819                      Reaction                               
Name
3alpha,7alpha-dihydroxy-5beta-cholestane:NADP+ oxidoreductase (B-specific)
Definition
3alpha,7alpha-Dihydroxy-5beta-cholestane + NADP+ <=> 7alpha-Hydroxy-5beta-cholestan-3-one + NADPH + H+
Equation
C05452 + C00006 <=> C05451 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC00144  C05451_C05452
Enzyme
1.1.1.50
Pathway
rn00120  Primary bile acid biosynthesis
rn01100  Metabolic pathways
Module
M00104  Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.50
     R04819  3alpha,7alpha-Dihydroxy-5beta-cholestane + NADP+ <=> 7alpha-Hydroxy-5beta-cholestan-3-one + NADPH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.1.1.50
   R10423  3alpha-Hydroxysteroid <=> 3-Oxosteroid
    R04819  3alpha,7alpha-Dihydroxy-5beta-cholestane <=> 7alpha-Hydroxy-5beta-cholestan-3-one
Orthology
K00037  3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225]

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
   SABIO-RK (1)   
Gene (49)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (48)   
All databases (65)   

Download RDF
DBGET integrated database retrieval system