KEGG   REACTION: R05066Help
Entry
R05066                      Reaction                               

Name
3-Hydroxy-2-methylpropanoate:NAD+ oxidoreductase
Definition
(S)-3-Hydroxyisobutyrate + NAD+ <=> (S)-Methylmalonate semialdehyde + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00099  C06001_C06002
Enzyme
1.1.1.31        1.1.1.35
Pathway
rn00280  Valine, leucine and isoleucine degradation
rn01100  Metabolic pathways
Orthology
K00020  3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]
K00022  3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
K01782  3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
K01825  3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
K07514  enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
Other DBs
RHEA: 31278

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