KEGG   Rattus norvegicus (rat): 24414
Entry
24414             CDS       T01003                                 
Symbol
Grm1
Name
(RefSeq) metabotropic glutamate receptor 1 isoform alpha precursor
  KO
K04603  metabotropic glutamate receptor 1
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04020  Calcium signaling pathway
rno04068  FoxO signaling pathway
rno04072  Phospholipase D signaling pathway
rno04080  Neuroactive ligand-receptor interaction
rno04082  Neuroactive ligand signaling
rno04540  Gap junction
rno04720  Long-term potentiation
rno04723  Retrograde endocannabinoid signaling
rno04724  Glutamatergic synapse
rno04730  Long-term depression
rno04742  Taste transduction
rno04915  Estrogen signaling pathway
rno05017  Spinocerebellar ataxia
rno05022  Pathways of neurodegeneration - multiple diseases
rno05215  Prostate cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    24414 (Grm1)
   04020 Calcium signaling pathway
    24414 (Grm1)
   04072 Phospholipase D signaling pathway
    24414 (Grm1)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    24414 (Grm1)
   04082 Neuroactive ligand signaling
    24414 (Grm1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    24414 (Grm1)
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    24414 (Grm1)
  09156 Nervous system
   04724 Glutamatergic synapse
    24414 (Grm1)
   04720 Long-term potentiation
    24414 (Grm1)
   04730 Long-term depression
    24414 (Grm1)
   04723 Retrograde endocannabinoid signaling
    24414 (Grm1)
  09157 Sensory system
   04742 Taste transduction
    24414 (Grm1)
 09160 Human Diseases
  09162 Cancer: specific types
   05215 Prostate cancer
    24414 (Grm1)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    24414 (Grm1)
   05022 Pathways of neurodegeneration - multiple diseases
    24414 (Grm1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:rno01009]
    24414 (Grm1)
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:rno04030]
    24414 (Grm1)
Protein phosphatases and associated proteins [BR:rno01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     24414 (Grm1)
G protein-coupled receptors [BR:rno04030]
 Metabotropic glutamate receptor family
  Glutamate (metabotropic)
   24414 (Grm1)
SSDB
Motif
Pfam: ANF_receptor 7tm_3 GluR_Homer-bdg NCD3G DUF5438
Other DBs
NCBI-GeneID: 24414
NCBI-ProteinID: NP_058707
RGD: 2742
Ensembl: ENSRNOG00000014290
UniProt: P23385 A6JP39 G3V7U1
Structure
Position
1:complement(6878542..7273447)
AA seq 1199 aa
MVRLLLIFFPMIFLEMSILPRMPDRKVLLAGASSQRSVARMDGDVIIGALFSVHHQPPAE
KVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSI
EFIRDSLISIRDEKDGLNRCLPDGQTLPPGRTKKPIAGVIGPGSSSVAIQVQNLLQLFDI
PQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESG
MDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLL
SAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLD
TNTRNPWFPEFWQHRFQCRLPGHLLENPNFKKVCTGNESLEENYVQDSKMGFVINAIYAM
AHGLQNMHHALCPGHVGLCDAMKPIDGRKLLDFLIKSSFVGVSGEEVWFDEKGDAPGRYD
IMNLQYTEANRYDYVHVGTWHEGVLNIDDYKIQMNKSGMVRSVCSEPCLKGQIKVIRKGE
VSCCWICTACKENEFVQDEFTCRACDLGWWPNAELTGCEPIPVRYLEWSDIESIIAIAFS
CLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQ
RLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTL
VVTLIIMEPPMPILSYPSIKEVYLICNTSNLGVVAPVGYNGLLIMSCTYYAFKTRNVPAN
FNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIA
KPERNVRSAFTTSDVVRMHVGDGKLPCRSNTFLNIFRRKKPGAGNANSNGKSVSWSEPGG
RQAPKGQHVWQRLSVHVKTNETACNQTAVIKPLTKSYQGSGKSLTFSDASTKTLYNVEEE
DNTPSAHFSPPSSPSMVVHRRGPPVATTPPLPPHLTAEETPLFLADSVIPKGLPPPLPQQ
QPQQPPPQQPPQQPKSLMDQLQGVVTNFGSGIPDFHAVLAGPGTPGNSLRSLYPPPPPPQ
HLQMLPLHLSTFQEESISPPGEDDDDDSERFKLLQEFVYEREGNTEEDELEEEEDLPTAS
KLTPEDSPALTPPSPFRDSVASGSSVPSSPVSESVLCTPPNVTYASVILRDYKQSSSTL
NT seq 3600 nt   +upstreamnt  +downstreamnt
atggtccggctcctcttgattttcttcccaatgatctttttggagatgtccattttgccc
aggatgcctgacagaaaagtattgctggcaggtgcctcgtcccagcgctccgtggcgaga
atggacggagatgtcatcatcggagccctcttctcagtccatcaccagcctccagccgag
aaggtacccgaaaggaagtgtggggagatcagggaacagtatggtatccagagggtggag
gccatgttccacacgttggataagattaacgcggacccggtgctcctgcccaacatcact
ctgggcagtgagatccgggactcctgctggcactcttcagtggctctcgaacagagcatc
gaattcatcagagactccctgatttccatccgagatgagaaggatgggctgaaccgatgc
ctgcctgatggccagaccctgccccctggcaggactaagaagcctattgctggagtgatc
ggccctggctccagctctgtggccattcaagtccagaatcttctccagctgttcgacatc
ccacagatcgcctattctgccacaagcatagacctgagtgacaaaactttgtacaaatac
ttcctgagggtggtcccttctgacactttgcaggcaagggcgatgctcgacatagtcaag
cgttacaactggacctatgtctcagcagtccacacagaagggaattacggcgagagtgga
atggatgctttcaaagaactggctgcccaggaaggcctctgcatcgcacactcggacaaa
atctacagcaatgctggcgagaagagctttgaccggctcctgcgtaaactccgggagcgg
cttcccaaggccagggttgtggtctgcttctgcgagggcatgacagtgcggggcttactg
agtgccatgcgccgcctgggcgtcgtgggcgagttctcactcattggaagtgatggatgg
gcagacagagatgaagtcatcgaaggctatgaggtggaagccaacggagggatcacaata
aagcttcagtctccagaggtcaggtcatttgatgactacttcctgaagctgaggctggac
accaacacaaggaatccttggttccctgagttctggcaacatcgcttccagtgtcgccta
cctggacacctcttggaaaaccccaactttaagaaagtgtgcacaggaaatgaaagcttg
gaagaaaactatgtccaggacagcaaaatgggatttgtcatcaatgccatctatgccatg
gcacatgggctgcagaacatgcaccatgctctgtgtcccggccatgtgggcctgtgtgat
gctatgaaacccattgatggcaggaagctcctggatttcctcatcaaatcctcttttgtc
ggagtgtctggagaggaggtgtggttcgatgagaagggggatgctcccggaaggtatgac
attatgaatctgcagtacacagaagctaatcgctatgactatgtccacgtggggacctgg
catgaaggagtgctgaatattgatgattacaaaatccaaatgaacaaaagcggaatggta
cgatctgtgtgcagtgagccttgcttaaagggtcagattaaggtcatacggaaaggagaa
gtgagctgctgctggatctgcacggcctgcaaagagaatgagtttgtgcaggacgagttc
acctgcagagcctgtgacctggggtggtggcccaacgcagagctcacaggctgtgagccc
attcctgtccgttatcttgagtggagtgacatagaatctatcatagccatcgccttttct
tgcctgggcatcctcgtgacgctgtttgtcaccctcatcttcgttctgtaccgggacaca
cccgtggtcaaatcctccagtagggagctctgctatatcattctggctggtattttcctc
ggctatgtgtgccctttcaccctcatcgccaaacctactaccacatcctgctacctccag
cgcctcctagttggcctctcttctgccatgtgctactctgctttagtgaccaaaaccaat
cgtattgcacgcatcctggctggcagcaagaagaagatctgcacccggaagcccagattc
atgagcgcttgggcccaagtgatcatagcctccattctgattagtgtacagctaacacta
gtggtgaccttgatcatcatggagcctcccatgcccattttgtcctacccgagtatcaag
gaagtctaccttatctgcaataccagcaacctgggtgtagtggcccctgtgggttacaat
ggactcctcatcatgagctgtacctactatgccttcaagacccgcaacgtgccggccaac
ttcaatgaggctaaatacatcgccttcaccatgtacactacctgcatcatctggctggct
ttcgttcccatttactttgggagcaactacaagatcatcactacctgcttcgcggtgagc
ctcagtgtgacggtggccctggggtgcatgtttactccgaagatgtacatcatcattgcc
aaacctgagaggaacgtccgcagtgccttcacgacctctgatgttgtccgcatgcacgtc
ggtgatggcaaactgccgtgccgctccaacaccttcctcaacattttccggagaaagaag
cccggggcagggaatgccaattctaacggcaagtctgtgtcatggtctgaaccaggtgga
agacaggcgcccaagggacagcacgtgtggcagcgcctctctgtgcacgtgaagaccaac
gagacggcctgtaaccaaacagccgtaatcaaacccctcactaaaagttaccaaggctct
ggcaagagcctgaccttttcagatgccagcaccaagaccctttacaatgtggaagaagag
gacaataccccttctgctcacttcagccctcccagcagcccttctatggtggtgcaccga
cgcgggccacccgtggccaccacaccacctctgccaccccatctgaccgcagaagagacc
cccctgttcctggctgattccgtcatccccaagggcttgcctcctcctctcccgcagcag
cagccacagcagccgccccctcagcagcccccgcagcagcccaagtccctgatggaccag
ctgcaaggcgtagtcaccaacttcggttcggggattccagatttccatgcggtgctggca
ggcccggggacaccaggaaacagcctgcgctctctgtacccgcccccgcctccgccgcaa
cacctgcagatgctgcccctgcacctgagcaccttccaggaggagtccatctcccctcct
ggggaggacgacgatgatgacagtgagagattcaagctcctgcaggagttcgtgtacgag
cgcgaagggaacaccgaagaagatgaattggaagaggaggaggacctgcccacagccagc
aagctgacccctgaggattctcctgccctgacgcctccttctcctttccgagattccgtg
gcctctggcagctcagtgcccagttcccccgtatctgagtcggtcctctgcacccctcca
aatgtgacctacgcctctgtcattctgagggactacaagcaaagctcttccaccctgtag

  All links  
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (8)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (16)   
   RefSeq(nuc) (4)   
   GenBank (6)   
   EMBL (6)   
3D Structure (5)   
   PDB (5)   
Protein domain (5)   
   Pfam (5)   
All databases (39)   

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