KEGG   Rattus norvegicus (rat): 25375Help
Entry
25375             CDS       T01003                                 

Gene name
Aldh3a1, AHDC, Ahd-c, Aldh, Aldh3
Definition
(RefSeq) aldehyde dehydrogenase 3 family, member A1
  KO
K00129  aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00010  Glycolysis / Gluconeogenesis
rno00340  Histidine metabolism
rno00350  Tyrosine metabolism
rno00360  Phenylalanine metabolism
rno00410  beta-Alanine metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno01100  Metabolic pathways
rno05204  Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    25375 (Aldh3a1)
  09105 Amino acid metabolism
   00340 Histidine metabolism
    25375 (Aldh3a1)
   00350 Tyrosine metabolism
    25375 (Aldh3a1)
   00360 Phenylalanine metabolism
    25375 (Aldh3a1)
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    25375 (Aldh3a1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    25375 (Aldh3a1)
   00982 Drug metabolism - cytochrome P450
    25375 (Aldh3a1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis
    25375 (Aldh3a1)
Enzymes [BR:rno01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.5  aldehyde dehydrogenase [NAD(P)+]
     25375 (Aldh3a1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Aldedh MukF_M Cir_Bir_Yir
Motif
Other DBs
NCBI-GeneID: 25375
NCBI-ProteinID: NP_114178
RGD: 2088
Ensembl: ENSRNOG00000002331
UniProt: P11883
Structure
PDB: 

Position
10q22
AA seq 453 aa AA seqDB search
MSSISDTVKRAREAFNSGKTRSLQFRIQQLEALQRMINENLKSISGALASDLGKNEWTSY
YEEVAHVLEELDTTIKELPDWAEDEPVAKTRQTQQDDLYIHSEPLGVVLVIGAWNYPFNL
TIQPMVGAVAAGNAVILKPSEVSGHMADLLATLIPQYMDQNLYLVVKGGVPETTELLKER
FDHIMYTGSTAVGKIVMAAAAKHLTPVTLELGGKSPCYVDKDCDLDVACRRIAWGKFMNS
GQTCVAPDYILCDPSIQNQIVEKLKKSLKDFYGEDAKQSRDYGRIINDRHFQRVKGLIDN
QKVAHGGTWDQSSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSLEEAIQFINQREK
PLALYVFSNNEKVIKKMIAETSSGGVTANDVIVHITVPTLPFGGVGNSGMGAYHGKKSFE
TFSHRRSCLVKSLLNEEAHKARYPPSPAKMPRH
NT seq 1362 nt NT seq  +upstreamnt  +downstreamnt
atgagcagtatcagtgacaccgtgaaacgggccagggaggcctttaactccggcaagact
cgatcgctgcagttccgaatccagcagttggaggcgctgcagcgcatgatcaatgagaac
ctgaaaagcatctctggggcgctggcctctgacctgggcaagaacgaatggacctcctac
tatgaggaagtggctcacgtactggaggagcttgataccacaattaaggagctccctgat
tgggctgaggatgagcctgtggccaagactcgccagacccagcaggatgacctctacatc
cactcggagcccctgggtgtggtccttgtcataggtgcttggaactaccccttcaacctc
accatccagcccatggtgggtgccgttgctgcaggaaacgcagtgatcctcaagccctca
gaagtgagcgggcacatggcagacctgctagcgacactcatccctcagtatatggaccag
aatctgtacctagtggtcaaagggggtgtccctgaaaccacggagctgctcaaagagagg
tttgaccacatcatgtacactgggagcacagccgtagggaagattgttatggccgctgcc
gccaagcatctgactcctgtcaccctggagcttggagggaaaagcccttgttacgtggac
aaggactgtgatctagatgtggcttgcaggcgtatcgcctgggggaaatttatgaacagt
ggccagacctgtgtggccccagactacatcctctgtgacccctcgattcagaaccaaatc
gtggagaagctcaagaagtcactcaaagatttctatggggaagatgctaagcagtcccgt
gattatgggaggatcatcaatgaccgtcacttccagcgggtcaaaggcctgattgacaac
cagaaagtagcccatggaggcacttgggaccagtcctcacgatacatagctccaaccatc
ctggtggatgtggacccccagtccccagtgatgcaggaggagatctttgggccggtgatg
cccattgtgtgtgttcgaagcttggaggaggccattcaatttatcaaccagcgtgagaag
cccctggcactctatgtgttctccaacaatgagaaggtgatcaagaaaatgatcgcagag
acatccagcggtggagtgacagccaatgacgtcattgttcacatcaccgtgcccactttg
ccctttggtggtgtggggaacagcggcatgggggcctaccatggcaagaaaagcttcgag
accttctcccaccgccgctcttgcctggtgaagtctctgttgaatgaagaagctcacaag
gccaggtatcccccaagcccagccaagatgccccggcactga

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