KEGG T01003: 25398

Rattus norvegicus (rat): 25398

Entry

25398             CDS       T01003

Symbol

Cacna1a

Name

(RefSeq) voltage-dependent P/Q-type calcium channel subunit alpha-1A

K04344

voltage-dependent calcium channel P/Q type alpha-1A

Organism

rno Rattus norvegicus (rat)

Pathway

rno04010

MAPK signaling pathway

rno04020

Calcium signaling pathway

rno04721

Synaptic vesicle cycle

rno04723

Retrograde endocannabinoid signaling

rno04724

Glutamatergic synapse

rno04725

Cholinergic synapse

rno04726

Serotonergic synapse

rno04727

GABAergic synapse

rno04728

Dopaminergic synapse

rno04730

Long-term depression

rno04742

Taste transduction

rno04930

Type II diabetes mellitus

rno05017

Spinocerebellar ataxia

rno05032

Morphine addiction

rno05033

Nicotine addiction

rno05207

Chemical carcinogenesis - receptor activation

Brite

KEGG Orthology (KO) [BR:rno00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    25398 (Cacna1a)
   04020 Calcium signaling pathway
    25398 (Cacna1a)
09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    25398 (Cacna1a)
   04727 GABAergic synapse
    25398 (Cacna1a)
   04725 Cholinergic synapse
    25398 (Cacna1a)
   04728 Dopaminergic synapse
    25398 (Cacna1a)
   04726 Serotonergic synapse
    25398 (Cacna1a)
   04730 Long-term depression
    25398 (Cacna1a)
   04723 Retrograde endocannabinoid signaling
    25398 (Cacna1a)
   04721 Synaptic vesicle cycle
    25398 (Cacna1a)
  09157 Sensory system
   04742 Taste transduction
    25398 (Cacna1a)
09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    25398 (Cacna1a)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    25398 (Cacna1a)
  09165 Substance dependence
   05032 Morphine addiction
    25398 (Cacna1a)
   05033 Nicotine addiction
    25398 (Cacna1a)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    25398 (Cacna1a)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:rno04040]
    25398 (Cacna1a)
Ion channels [BR:rno04040]
Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   25398 (Cacna1a)

SSDB

Motif

Pfam:

Ion_trans Ca_chan_IQ GPHH PKD_channel

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

RGD:

Ensembl:

UniProt:

Position

19:complement(40425560..40724810)

AA seq 2368 aa
MARFGDEMPGRYGAGGGGSGPAAGVVVGAAGGRGAGGSRQGGQPGAQRMYKQSMAQRART
MALYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALE
QHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIVALGFAFHKGSYLRNGWNVMDFVVVL
TGILATVGTEFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAIL
IFAIIGLEFYMGKFHTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPYWEGPNNGI
TQFDNILFAVLTVFQCITMEGWTDLLYNSNDASGNTWNWLYFIPLIIIGSFFMLNLVLGV
LSGEFAKERERVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDVEQRHPFD
GALRRATLKKSKTDLLNPEEAEDQLADIASVGSPFARASIKSAKLENSTFFHKKERRMRF
YIRRMVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYAEFIFLGLFMSEMFIKM
YGLGTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRIFKVTKYWA
SLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFDEGTPPTNFDTFPAAI
MTVFQILTGEDWNEVMYDGIKSQGGVQGGMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLA
NAQELTKDEQEEEEAANQKLALQKAKEVAEVSPLSAANMSIAVKEQQKNQKPAKSVWEQR
TSEMRKQNLLASREALYGDAAERWPTTYARPLRPDVKTHLDRPLVVDPQENRNNNTNKSR
APEALRQTARPRESARDPDARRAWPSSPERAPGREGPYGRESEPQQREHAPPREHVPWDA
DPERAKAGDAPRRHTHRPVAEGEPRRHRARRRPGDEPDDRPERRPRPRDATRPARAADGE
GDDGERKRRHRHGPPAHDDRERRHRRRKESQGSGVPMSGPNLSTTRPIQQDLGRQDLPLA
EDLDNMKNNKLATGEPASPHDSLGHSGLPPSPAKIGNSTNPGPALATNPQNAASRRTPNN
PGNPSNPGPPKTPENSLIVTNPSSTQPNSAKTARKPEHMAVEIPPACPPLNHTVVQVNKN
ANPDPLPKKEEEKKEEEEADPGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMC
ILMVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYF
RDLWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDC
VVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFERDCRGKYLLYEKNEV
KARDREWKKYDFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMSI
FYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHMP
QNKQSFQYRMWQFVVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSLF
SLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITDILVTEFGNNFINLSFLRLFRAARLI
KLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDGEDEDSDED
EFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGKPCDKNSGIQKPECGNEFAYF
YFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEYVRVWAEYDPAACGRIHY
KDMYSLLRVISPPLGLGKKCPHRVACKRLLRMDLPVADDNTVHFNSTLMALIRTALDIKI
AKGGADKQQMDAELRKEMMAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQS
KAKKLQAMREEQNRTPLMFQRMEPPSPTQEGGPSQNALPSTQLDPGGGLMAQESSMKESP
SWVTQRAQEMFQKTGTWSPERGPPIDMPNSQPNSQSVEMREMGTDGYSDSEHYLPMEGQT
RAASMPRLPAENQRRRGRPRGNNLSTISDTSPMKRSASVLGPKARRLDDYSLERVPPEEN
QRYHQRRRDRGHRTSERSLGRYTDVDTGLGTDLSMTTQSGDLPSKDRDQDRGRPKDRKHR
PHHHHHHHHHHPPAPDRERYAQERPDTGRARAREQRWSRSPSEGREHATHRQGSSSVSGS
PAPSTSGTSTPRRGRRQLPQTPCTPRPLVSYSPAPRRPAARRMAGPPAPPGGSPRGCRRA
PRWPAHAPEGPRPRGADYTEPDSPREPPGGAHEPAPRSPRTPRAAGCASPRHGRRLPNGY
YAGHGAPRPRTARRGAHDAYSESEDDWC

NT seq 7107 nt +upstreamnt +downstreamnt
atggcccgctttggagacgagatgccgggccgctacggcgcaggcggaggaggctcaggg
ccggccgccggggtggtcgtgggcgccgcgggcggccgaggagccgggggcagccggcag
ggcgggcagcccggagcgcagaggatgtacaagcagtcgatggcgcagagagcgcggacc
atggccctctacaaccccatccctgtccgccagaactgcctcacggtcaaccgctccctg
ttcctcttcagtgaagacaacgtggtgagaaaatacgccaaaaagatcacggaatggcct
cccttcgagtacatgatcctggccaccatcattgctaactgcatcgtcctggccctggag
cagcacctccctgatgatgacaagacacccatgtccgagcggctggatgacacagaaccc
tatttcattggcatcttctgttttgaggctggaattaagatcgtggctcttggctttgcc
ttccacaaaggctcctacctgaggaatggctggaacgtcatggactttgtcgtggtgcta
acaggcatcttggccactgtcgggacggagtttgatctacggacactgagggcggttcgt
gtgctgcggccactcaagctggtgtctggaatcccaagtttacaagtcgtcctgaagtca
atcatgaaggcgatgatccctctgctgcagatcggcctcctcctgttttttgcaatcctt
atttttgcaatcatagggttagaattttatatgggaaaatttcataccacctgctttgaa
gaggggacagacgacatccagggtgagtcgccagctccgtgtgggacagaggagcctgcc
cgcacctgccccaacgggaccaaatgtcagccgtactgggaagggcccaacaacggcatc
actcagttcgacaacatcctgtttgctgtgctcactgttttccagtgcatcaccatggaa
ggctggactgatctcctctacaatagcaacgatgcctcagggaacacttggaactggttg
tacttcatccccctcatcatcatcggctccttttttatgctgaaccttgtgctgggtgtg
ctgtctggggagtttgccaaagaaagggaacgtgtagagaaccgaagggcttttctgaag
ctcagaagacaacagcagattgaacgtgagctcaatggatacatggagtggatctcgaaa
gcagaagaggtgatcctcgcggaggacgagacagacgtggagcagaggcacccttttgat
ggagctcttcggagagctactctgaagaaaagcaagacggacctgctcaaccctgaggag
gcggaggaccagcttgctgacatcgcgtctgtggggtctcccttcgccagagccagcatc
aaaagtgccaagctggagaattcgacttttttccacaaaaaggagagaagaatgcgtttc
tacatccgccgcatggtcaaaactcaggccttctactggaccgtgctcagtctggtagcc
ctcaacacgctgtgcgtcgccattgtccactacaaccagcccgagtggctctccgacttc
ctctactatgcagaattcattttcttaggactctttatgtccgaaatgtttataaaaatg
tatgggctcgggacacggccttacttccactcttccttcaactgctttgactgtggggtc
atcatcgggagcatctttgaagtcatctgggccgtcatcaaaccgggtacatcctttgga
atcagcgtgttacgagctctcaggttactgcgtattttcaaagtcacaaagtactgggca
tctctcagaaacctggttgtctccctcctcaactccatgaaatccatcataagtctgctg
ttcctcctcttcctcttcattgtcgtctttgccctcttggggatgcagctgtttggtggc
cagtttaattttgacgaggggactcctcccaccaacttcgacacttttccagcagcaata
atgactgtgtttcagatcctgactggcgaggattggaatgaggtcatgtatgatgggatc
aagtctcaggggggcgtgcagggcggcatggtgttctccatctacttcatcgtcctcacc
ctcttcgggaactacaccctgctgaacgtgttcttggctatcgcggtggacaacctggcc
aacgcccaggaactcaccaaggatgaacaagaagaggaagaggcagccaatcagaaactg
gctctacagaaagccaaggaggtggcagaagtgagtcccctgtctgcagccaacatgtcc
atagctgtgaaggaacagcagaagaaccagaagcctgccaagtcggtgtgggagcagcgc
accagcgagatgcgcaagcagaacctgctggctagccgcgaggcgctgtacggggacgcg
gctgagcgctggcccaccacttacgcgcgcccgctgcggccggacgtgaagacgcacttg
gaccggccgctcgtggtggacccgcaggagaaccgtaacaacaacaccaacaagagccgt
gcgccagaagcgctgcgccaaaccgcgcggccccgcgagagcgcgcgcgaccccgacgcg
cggcgcgcctggcccagcagccctgagcgcgcccctggacgagagggcccgtatggccgc
gagagcgagccgcaacagcgcgagcacgcgccaccccgcgagcacgtaccctgggacgcg
gatcctgagcgcgccaaggccggggacgcgccccgccgccacacgcaccggcctgtggcc
gagggcgagcctcgtcgccaccgcgcgcgccgccggcccggggacgaaccggacgacaga
ccggagcgcaggccgcgtccccgcgacgccactaggccggcccgcgctgcagacggcgaa
ggcgatgatggggagcgcaagcggcgacaccgacacgggccgccggcccacgatgacagg
gagcgcagacaccggcgcagaaaagagagccagggctctggggtccccatgtctggtccc
aacctgtccaccaccaggccaatccagcaggatctgggccgccaggacctgccactggct
gaggacctggacaacatgaagaacaacaagttggccaccggggagcctgccagtccccac
gacagcctgggccacagtggccttccccctagccctgccaagatcgggaacagcaccaac
cctggtcccgccttggccaccaatccccagaatgctgccagccgcaggacgcccaacaac
ccgggcaacccgtccaaccccggcccccccaagactcccgagaacagccttatcgtcacc
aaccccagcagcacccagcccaactcagcaaagactgccaggaaacccgagcacatggcg
gtggagatccccccggcctgcccgcccctcaaccacactgtggtccaagtaaacaaaaac
gccaacccagacccactgccaaagaaagaggaagagaagaaggaggaagaggaggcagac
cccggggaggatggcccaaagcccatgccgccctacagctccatgttcatcctctccacc
accaacccccttcgccggctgtgccattacatcctgaacctgcgctacttcgagatgtgc
atcctcatggtcattgccatgagtagcatcgcgctggccgccgaggacccggtgcagccc
aacgcaccccgcaacaacgtgctgcgatattttgactatgttttcacaggagtgtttacc
tttgagatggtgatcaagatgatcgacctgggcctcgtcctgcatcagggggcctatttc
cgtgacctgtggaacattctggacttcatagtggtcagtggggccctggtggcctttgcc
ttcactggcaatagcaaaggaaaggacatcaacaccatcaagtccctccgagtcctccgg
gtgctacgacctctaaagaccatcaagcggctgcctaagttgaaggccgtatttgactgc
gtggtgaactcgctcaagaacgtcttcaacatcctcattgtctacatgctcttcatgttc
atcttcgccgtggtggccgtgcagctcttcaagggcaaattcttccactgcacggacgag
tccaaggagtttgagagagactgtcgaggcaaatacctcctttacgagaagaacgaggta
aaggcgcgggaccgcgagtggaagaaatacgacttccactacgacaacgtgctctgggcc
ctgctcacgctctttacggtgtccacgggagagggctggccacaggtcctcaagcactca
gtggatgccacttttgagaaccagggccccagccccgggtaccgcatggaaatgtccatc
ttctacgtggtctactttgtggtgtttcccttcttctttgtcaatatctttgtggccttg
atcatcatcaccttccaggagcagggagacaagatgatggaagaatacagcctagagaaa
aatgagagggcctgcatcgactttgccatcagtgccaagccgctgaccaggcacatgccc
cagaacaagcagagcttccagtatcgaatgtggcagttcgtggtgtccccaccctttgag
tacaccatcatggccatgatcgctctcaacaccatcgtgctaatgatgaagttctatgga
gcctctgtggcctatgaaaacgcccttcgagtgttcaacattgtcttcacctccctcttc
tctctcgaatgtgtgctcaaagtcatggcttttgggattctgaattatttccgcgatgcc
tggaacatcttcgactttgtgactgttctgggcagcatcacagacatcctcgtcaccgag
tttgggaataacttcatcaacctgagctttctccgcctcttccgtgctgcccgactcatc
aaactcctccgccagggttacaccatccgcattctcctctggactttcgtgcagtctttc
aaggccctaccttatgtctgtctgctgatcgccatgctcttcttcatctatgccatcatc
gggatgcaggtgtttggcaacatcggcattgatggggaagatgaggacagcgatgaggat
gagttccaaatcacggagcacaataacttccggaccttcttccaagctctcatgcttctc
ttccggagcgccacaggggaagcgtggcacaacatcatgctgtcctgcctcagcgggaag
ccatgcgacaagaactccgggatccaaaaaccagagtgtggcaacgagttcgcctatttt
tactttgtctcgttcatcttcctttgctcatttctgatgctgaatctctttgttgctgtc
atcatggacaacttcgagtacctcacccgagattcctccatcctgggcccccaccacctg
gatgagtacgtgcgtgtctgggcagagtatgaccctgctgcctgcggccgcattcactat
aaggacatgtacagtttattgcgagtaatatcgccccctctcggcttaggcaagaaatgt
cctcatagggttgcttgcaagaggctcttgcggatggacctacccgtagcggatgacaac
accgttcacttcaactccaccttgatggctctgatccgaaccgccctggatatcaaaatc
gcaaagggtggagctgacaagcagcaaatggacgcagagctccgcaaggaaatgatggcc
atttggcccaacctgtctcagaagaccttggatctgctggtcacacctcacaagtccacg
gacctgacagtgggtaagatctacgcagccatgatgatcatggagtactaccggcagagc
aaggccaagaagctgcaggccatgcgagaggagcagaaccggacaccactcatgttccag
cgcatggagcctccatcgccaacacaggagggaggacccagccaaaacgcccttccctcc
actcagctggaccccggaggaggcctgatggctcaagaaagcagcatgaaggagagcccg
tcctgggtgacccagcgggcacaggagatgttccagaagactggtacctggagcccagag
cgagggccacccatcgacatgcctaacagccagcccaactcccagtctgtggagatgaga
gaaatgggaactgatggctactcagacagcgaacactacctccccatggaaggacagacc
agggccgcctccatgccccgcctcccagcagagaaccagaggagaaggggccggccacgt
ggaaataacctcagtaccatctctgataccagccccatgaagcgctcagcctccgtgctg
ggacccaaagcccggcgactggatgactactcactagagcgggtaccacctgaggagaac
caaaggtaccaccaacgccgccgggaccgtggccaccgcacctctgagcgctctctgggc
cgatacactgatgtggacacaggcctggggacagatctgagcatgaccacccaatcgggt
gacctgccctccaaagatcgggaccaggaccggggccggcccaaggaccggaagcatcgg
ccacaccaccaccaccaccatcatcaccatcatcccccggccccggaccgggagcgctac
gcacaggagcggccggacaccggccgggcgcgggcccgggagcagcgctggtcccgctcg
cccagcgagggtcgggagcacgcgacacacagacagggcagtagttccgtcagtggaagc
ccagccccctctacgtccggcaccagcacgccgcggcgcggccgccgccagctcccccag
accccctgcaccccgcggccgcttgtgtcctactcgcccgctccgcgcaggcctgcggcg
cgcaggatggcgggtcccccagcgccccctggcggctcgccgcggggttgccgccgtgcg
ccgcgctggcctgcgcatgcgcctgagggcccgcggccgcgcggtgccgactacaccgag
cccgacagcccgcgcgagccgccagggggcgcgcatgagcccgcgccgcggtcgcccagg
actccgcgcgccgcgggctgcgcgtcaccgcgccacggccgcaggctgcccaatggttac
tacgcggggcacggcgcgccacggccgcgcacagcccgcaggggcgcgcacgacgcgtac
agcgagagcgaggacgactggtgctaa

All links

Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (16)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (37)   
   RefSeq(nuc) (13)   
   GenBank (12)   
   EMBL (12)   
Protein domain (4)   
   Pfam (4)   
All databases (62)   

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