KEGG   Rattus norvegicus (rat): 297989
Entry
297989            CDS       T01003                                 
Symbol
Rig1
Name
(RefSeq) antiviral innate immune response receptor RIG-I
  KO
K12646  ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04064  NF-kappa B signaling pathway
rno04622  RIG-I-like receptor signaling pathway
rno04623  Cytosolic DNA-sensing pathway
rno05160  Hepatitis C
rno05161  Hepatitis B
rno05162  Measles
rno05164  Influenza A
rno05168  Herpes simplex virus 1 infection
rno05169  Epstein-Barr virus infection
rno05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    297989 (Rig1)
 09150 Organismal Systems
  09151 Immune system
   04622 RIG-I-like receptor signaling pathway
    297989 (Rig1)
   04623 Cytosolic DNA-sensing pathway
    297989 (Rig1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05161 Hepatitis B
    297989 (Rig1)
   05160 Hepatitis C
    297989 (Rig1)
   05171 Coronavirus disease - COVID-19
    297989 (Rig1)
   05164 Influenza A
    297989 (Rig1)
   05162 Measles
    297989 (Rig1)
   05168 Herpes simplex virus 1 infection
    297989 (Rig1)
   05169 Epstein-Barr virus infection
    297989 (Rig1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors [BR:rno04054]
    297989 (Rig1)
Enzymes [BR:rno01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.6  RNA 3'-5' helicase
     297989 (Rig1)
Pattern recognition receptors [BR:rno04054]
 Cytoplasmic pattern recognition receptors
  RIG-I-like receptors
   297989 (Rig1)
SSDB
Motif
Pfam: CARD_2 RIG-I_C RIG-I_C-RD DEAD ResIII Helicase_C AAA_25 zf-C2H2_aberr
Other DBs
NCBI-GeneID: 297989
NCBI-ProteinID: NP_001382000
RGD: 1309460
Ensembl: ENSRNOG00000006384
UniProt: D4ADT5
Position
5:complement(60117398..60165995)
AA seq 926 aa
MTAEQRQNLQAFRDYIKKILDPTYILSYMSSWLRDDEVQCIQAEKNNKGPIEAASLFLRY
LLELQTEGWFRAFLDALYHAGYCGLYEAIETWDFQKLEKLEEHRLLLRRLEPEFKATVSP
TDILSEISECLINQECEEIRQICFTKGRMAGAEKMVQCLLRSDKENWPKVLQFALEKDNS
KFSELWLVDKGVRRVDCKAVEDDGTEMASIQIFIQEEPECQNLSQNPGPPSEASPNNSHS
PLKPRNYQLELALPAKKGKNTVICAPTGCGKTFVSLLICEHHLKNFPHGQKGKVVFFANQ
IPVYEQQATVFSRYFERFGYNVAGISGATADNVSVQHIIENNDIVILTPQILVNSLNNGA
IPSLSVFTLMIFDECHNTSKHHPYNQIMFRYLDHKLGGSPDPLPQVIGLTASVGVGDAKT
VEEAMLHICKLCAALDASVIATVRDNVEELEQVVYKPQKISRKVESRASNTFKCIISQLM
REAERLAKNVSEELGKFFQIQNREFGTQKYEQWIVAVHKACTVFQMPDKDEESRICKALF
LYTSHLRKYNDALIISEDAQMKDALNYLKAFFHDVREAAFDETEQDLTRRFEEKLEELEN
VSRDPSNENPKLRDLYLILQEEYHLKPETKTILFVKTRALVDALKKWIEENPALSFLKPG
ILTGRGRTNQATGMTLPAQKCVLEAFRANADNNILIATSVADEGIDIAQCNLVILYEYVG
NVIKMIQTRGRGRARDSKCFLLTSSADVIEKEKANMVKEKIMNESILRLQTWDEVKFQKT
VHRIQLDEKLLRDSQHKPQPVPDRENKKLLCGKCKTFACYTADIRVVEKSHYTVLGDAFK
ERFVCKPHPKPKIYDSFEKKAKIFCAKQNCSHDWGIFVRYKTFEIPVIKIESFVVEDIES
GVQNRHSKWKDFHFERKQFNPEEMST
NT seq 2781 nt   +upstreamnt  +downstreamnt
atgaccgcagagcagcggcagaatctgcaagcattcagagactatatcaagaagattctg
gaccccacctacatcctcagctatatgagttcctggctccgggatgatgaggtgcagtgc
attcaggccgagaagaacaacaagggcccaatagaggccgcctcactgttcctccggtac
ctgttggagctgcagacagagggctggttccgggcctttttggatgccctgtaccatgca
ggttactgtggactttatgaagccatcgaaacttgggactttcaaaaacttgaaaagtta
gaggaacacagattacttttaagacgtttagagccggaatttaaggccacagttagcccg
acagatatcctttctgaaatatctgaatgtttgattaatcaggaatgtgaagaaatcaga
cagatctgcttcactaaagggaggatggcgggtgcggagaagatggtccaatgtcttctc
agatccgataaggagaactggccaaaggttttgcagtttgctttggagaaagacaacagc
aagtttagtgaactgtggctcgtcgataaaggtgtcagaagggttgactgtaaggctgtt
gaggatgacggaacagagatggccagcatacagattttcattcaggaagaaccggagtgt
cagaatctcagtcagaatcccggccctccttcagaagcgtctcctaataattcacacagc
ccattgaaaccaagaaattaccaactggagcttgccctgcctgccaagaaagggaaaaat
acagtaatatgtgctcctactggttgtggaaaaacctttgtgtcgcttctcatatgcgaa
catcatcttaaaaactttccgcacggacagaaagggaaagtggtcttttttgctaaccag
atccctgtgtatgaacagcaggccactgtgttctcacgatatttcgaaagatttgggtac
aatgtcgccggcatttcgggggcaacggctgataatgtgtcagtgcagcacatcattgaa
aacaatgacatcgtcatcctgacaccccagattcttgtgaacagtctcaacaatggagcc
atcccctcgctgtctgtcttcactctgatgatattcgacgagtgtcataacaccagcaaa
caccacccgtacaaccagatcatgttcagatacctagatcacaaactcggagggtcaccc
gacccactgcctcaggtcattgggctgactgcttccgttggtgttggagatgctaaaacc
gtggaggaagccatgctgcacatctgcaaactctgtgccgccctcgatgcctcagtgatt
gccacagtcagagacaacgtggaagaactggagcaggttgtttataagcctcagaaaatt
tccaggaaagtggaatcacgggcttcgaacacgtttaaatgcatcatatctcagctgatg
agggaggcagagaggctggcgaagaacgtctctgaggaacttggaaagttctttcaaatt
caaaatcgagaatttggcacccagaaatatgagcagtggattgtcgccgttcacaaagca
tgcacggtgtttcagatgcctgacaaagatgaggagagcaggatctgcaaggcgctcttt
ctgtacacctcccacttgcggaaatacaacgacgccctcatcatcagcgaggatgcacag
atgaaagacgctctaaattacctcaaagccttcttccatgatgtccgagaagcagcattt
gatgagactgagcaagatcttacgcggaggtttgaagaaaaactggaggaactagaaaac
gtttccagggatcccagcaacgagaatcctaaactaagagacctctacttgatcttacaa
gaagaataccacttaaagccggagaccaagaccattctcttcgtgaagaccagagcactt
gtggatgctttgaagaaatggattgaagaaaatcctgcactgagttttctaaaacctggc
atactgactggacgtggcagaacaaaccaggcaacagggatgacgctccctgcacagaag
tgtgtgttggaggcattcagagccaatgcggataacaatattctgattgctacctcggtc
gctgatgaaggcattgacattgctcagtgcaatctcgtcatcctgtatgagtacgtgggc
aacgtcatcaagatgatccaaaccagaggcagaggaagagcacgagatagcaagtgcttc
ctcctgaccagcagtgctgatgtgattgaaaaagaaaaggcgaacatggtcaaggaaaaa
ataatgaatgagtccatcttaagactgcagacatgggatgaagtgaaatttcaaaagacg
gttcaccgcatacagctggatgaaaaactcctcagggacagtcaacacaaaccacagccc
gtccccgacagagaaaacaagaaactgctgtgtggaaagtgcaagacttttgcgtgctac
acagctgacattcgagtggtcgagaaatcccactacactgtgcttggagatgcttttaag
gagcgctttgtgtgtaagccacaccctaaaccaaagatctatgatagttttgagaagaaa
gcaaaaatattctgtgccaaacagaactgcagccatgactgggggatttttgtgagatac
aagacgtttgagattccagtcataaaaatcgaaagcttcgttgttgaagatattgagagt
ggagttcagaaccggcactcaaagtggaaggactttcattttgaaagaaaacagttcaat
cccgaagaaatgtccacatga

  All links  
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (8)   
   Pfam (8)   
All databases (17)   

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