KEGG   Saccharomyces cerevisiae (budding yeast): YOR005C
Entry
YOR005C           CDS       T00005                                 
Symbol
DNL4, LIG4
Name
(RefSeq) DNA ligase (ATP) DNL4
  KO
K10777  DNA ligase 4 [EC:6.5.1.1]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce03450  Non-homologous end-joining
Brite
KEGG Orthology (KO) [BR:sce00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03450 Non-homologous end-joining
    YOR005C (DNL4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:sce03400]
    YOR005C (DNL4)
Enzymes [BR:sce01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.1  DNA ligase (ATP)
     YOR005C (DNL4)
DNA repair and recombination proteins [BR:sce03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    DNA Ligase 4 complex
     YOR005C (DNL4)
SSDB
Motif
Pfam: DNA_ligase_A_M DNA_ligase_A_N BRCT_2 BRCT RNA_ligase Fve DNA_ligase_A_C
Other DBs
NCBI-GeneID: 854166
NCBI-ProteinID: NP_014647
SGD: S000005531
UniProt: Q08387
Structure
Position
XV:complement(334509..337343)
AA seq 944 aa
MISALDSIPEPQNFAPSPDFKWLCEELFVKIHEVQINGTAGTGKSRSFKYYEIISNFVEM
WRKTVGNNIYPALVLALPYRDRRIYNIKDYVLIRTICSYLKLPKNSATEQRLKDWKQRVG
KGGNLSSLLVEEIAKRRAEPSSKAITIDNVNHYLDSLSGDRFASGRGFKSLVKSKPFLHC
VENMSFVELKYFFDIVLKNRVIGGQEHKLLNCWHPDAQDYLSVISDLKVVTSKLYDPKVR
LKDDDLSIKVGFAFAPQLAKKVNLSYEKICRTLHDDFLVEEKMDGERIQVHYMNYGESIK
FFSRRGIDYTYLYGASLSSGTISQHLRFTDSVKECVLDGEMVTFDAKRRVILPFGLVKGS
AKEALSFNSINNVDFHPLYMVFDLLYLNGTSLTPLPLHQRKQYLNSILSPLKNIVEIVRS
SRCYGVESIKKSLEVAISLGSEGVVLKYYNSSYNVASRNNNWIKVKPEYLEEFGENLDLI
VIGRDSGKKDSFMLGLLVLDEEEYKKHQGDSSEIVDHSSQEKHIQNSRRRVKKILSFCSI
ANGISQEEFKEIDRKTRGHWKRTSEVAPPASILEFGSKIPAEWIDPSESIVLEIKSRSLD
NTETNMQKYATNCTLYGGYCKRIRYDKEWTDCYTLNDLYESRTVKSNPSYQAERSQLGLI
RKKRKRVLISDSFHQNRKQLPISNIFAGLLFYVLSDYVTEDTGIRITRAELEKTIVEHGG
KLIYNVILKRHSIGDVRLISCKTTTECKALIDRGYDILHPNWVLDCIAYKRLILIEPNYC
FNVSQKMRAVAEKRVDCLGDSFENDISETKLSSLYKSQLSLPPMGELEIDSEVRRFPLFL
FSNRIAYVPRRKISTEDDIIEMKIKLFGGKITDQQSLCNLIIIPYTDPILRKDCMNEVHE
KIKEQIKASDTIPKIARVVAPEWVDHSINENCQVPEEDFPVVNY
NT seq 2835 nt   +upstreamnt  +downstreamnt
atgatatcagcactagattctatacccgagccccaaaactttgcgcctagtccagatttc
aaatggctttgtgaagagctatttgtgaagatacatgaagttcaaattaatggaacggcc
ggcactggcaaatcaaggtctttcaagtactatgaaataatatcgaatttcgtcgaaatg
tggagaaaaaccgtgggaaataatatatatcctgcactggttcttgctcttccctaccgc
gatagacgaatctataatattaaggattatgtattaataagaactatatgctcttacttg
aagttgccaaaaaattctgcaacagagcagcggttaaaagattggaaacagcgtgtcggt
aaaggtgggaatctttcttctcttcttgtggaagaaattgctaaaagaagggctgaacct
agctcaaaagcgattacaattgataacgtcaatcactatctggatagtttgagtggagac
aggttcgcttccggacgaggatttaagagtcttgtcaagtccaaacctttcctgcactgt
gtggagaatatgagtttcgtcgaattaaaatacttctttgatatcgtgcttaaaaataga
gtaataggaggtcaagagcacaaattgctaaactgctggcatcctgatgctcaggattat
cttagcgtgatatctgatttaaaggtggtaacttcaaaactttatgatccaaaagttcgt
ctaaaggatgatgatttgagtataaaagttggctttgcattcgccccccaattagccaaa
aaagtgaatctttcttatgagaaaatatgccgtacactacatgatgattttttggtagaa
gaaaaaatggatggagaacgaattcaagttcattatatgaattatggtgaatccataaaa
ttttttagtagacggggcatcgactatacctatttgtacggagcgagcttatcatcagga
actatatctcaacatttgaggtttacagatagtgttaaagaatgtgttttagatggagaa
atggtgacgtttgatgcaaaaagacgggtgattcttccattcggtcttgttaaaggaagt
gcaaaggaagcgctatcttttaatagtataaataatgttgactttcaccccttatatatg
gtgtttgatctgttatacctgaatgggacttcgttgacaccattaccccttcatcaaagg
aagcaatatctgaacagcattttaagtcccttgaaaaatattgtagaaatagtacgatct
tctagatgttatggtgtggagtcaatcaaaaagtctttagaagttgcaatctcactgggt
tcagaaggagttgttttgaaatattataattcaagttataatgtcgccagtcgaaacaac
aactggatcaaggtaaaacctgaatatttggaggaatttggagagaatttagacttaata
gtaataggcagagattctgggaaaaaagattcttttatgctagggttacttgtgctagat
gaagaagagtataaaaagcaccaaggagactcctctgaaattgtagaccactcaagccaa
gaaaaacacatacaaaattcaagaagaagggtgaaaaaaatactttcattctgttctatc
gcaaacggtatatctcaagaagaattcaaagaaatcgaccgcaaaacgagaggacattgg
aaaagaacctccgaagttgctccccctgcttcaattttagaatttggctcaaaaatacct
gccgaatggattgaccccagtgaatcaattgttctagaaataaaatcacggtctttggat
aacacagaaacgaatatgcagaagtacgctaccaattgtactttgtacggtggctattgt
aaaagaatacggtacgataaagaatggacagattgttacacacttaacgacttatacgaa
agtaggacggttaaatctaaccccagctatcaagcggaaaggtcacagcttggattgata
cggaaaaagagaaagagagtacttatttcagacagctttcaccaaaacaggaaacaactg
ccaatttcaaacatctttgccggattacttttttatgttctctctgactatgtcacggag
gacactggaatacggattacacgggcagaacttgaaaaaactattgtggaacatggtggt
aaactgatatataatgtaattttaaaacgtcattcaattggggacgttcggttaatcagc
tgtaaaactaccacggaatgcaaggctttaatagatcgaggatatgatatattgcaccca
aattgggtactcgattgtatagcatataagaggctcatcctgatcgagcccaattattgc
tttaacgtctctcaaaaaatgagagccgtcgctgaaaaaagggtagattgtttgggtgat
agttttgaaaatgacatttcggaaaccaaactgtcatcattgtataaatcacaactaagt
ctaccaccgatgggggaactcgagatagattctgaggttcggcggtttccattattttta
ttctccaacaggattgcatacgtaccacgtcgcaaaattagcacagaagatgacattata
gaaatgaaaattaagttgtttggtggaaaaataacagatcaacagtcactttgtaactta
ataattataccatatactgatcctattttgaggaaagactgcatgaatgaggtacacgaa
aaaataaaagaacaaataaaggcttctgatactataccgaaaatagccagggtcgttgcc
cctgaatgggtggatcattctattaatgaaaactgtcaagtgcctgaagaagacttcccc
gtagtcaactactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (30)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (25)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
3D Structure (1)   
   PDB (1)   
Protein domain (7)   
   Pfam (7)   
All databases (54)   

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