KEGG   PATHWAY: sgr00280
Entry
sgr00280                    Pathway                                

Name
Valine, leucine and isoleucine degradation - Streptomyces griseus
Class
Metabolism; Amino acid metabolism
Pathway map
sgr00280  Valine, leucine and isoleucine degradation
sgr00280

Module
sgr_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sgr00280]
Other DBs
GO: 0006550 0006552 0006574
Organism
Streptomyces griseus [GN:sgr]
Gene
SGR_1982  putative branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
SGR_5991  putative aminotransferase [KO:K00826] [EC:2.6.1.42]
SGR_3880  putative valine dehydrogenase [KO:K00271] [EC:1.4.1.23]
SGR_5330  putative dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SGR_4769  putative acyl-CoA dehydrogenase [KO:K00249] [EC:1.3.8.7]
SGR_5810  putative acyl-CoA dehydrogenase [KO:K00249] [EC:1.3.8.7]
SGR_6453  putative acyl-CoA dehydrogenase [KO:K00249] [EC:1.3.8.7]
SGR_1563  putative acyl-CoA dehydrogenase [KO:K00249] [EC:1.3.8.7]
SGR_4756  putative acyl-CoA dehydrogenase [KO:K11410] [EC:1.3.99.12]
SGR_6832  putative enoyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
SGR_3090  putative enoyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
SGR_1217  putative enoyl-CoA hydratase/isomerase [KO:K01692] [EC:4.2.1.17]
SGR_5500  putative enoyl-CoA hydratase/isomerase [KO:K01692] [EC:4.2.1.17]
SGR_1219  putative enoyl-CoA hydratase/isomerase [KO:K01692] [EC:4.2.1.17]
SGR_329  putative enoyl-CoA hydratase/isomerase [KO:K01692] [EC:4.2.1.17]
SGR_993  putative fatty acid oxidation complex alpha-subunit [KO:K01782] [EC:1.1.1.35 4.2.1.17 5.1.2.3]
SGR_1477  putative 3-oxoacyl-CoA thiolase [KO:K00632] [EC:2.3.1.16]
SGR_3093  putative acetyl/propionyl CoA carboxylase alpha subunit [KO:K01965] [EC:6.4.1.3]
SGR_2616  putative acyl-CoA carboxylase beta subunit [KO:K01966] [EC:6.4.1.3 2.1.3.15]
SGR_2621  putative acyl-CoA carboxylase alpha subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
SGR_4758  putative acetyl/propionyl CoA carboxylase alpha subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
SGR_2139  conserved hypothetical protein [KO:K05606] [EC:5.1.99.1]
SGR_6745  putative methylmalonyl-CoA mutase alpha subunit [KO:K01847] [EC:5.4.99.2]
SGR_6746  putative methylmalonyl-CoA mutase beta subunit [KO:K01847] [EC:5.4.99.2]
SGR_2730  putative isobutyryl-CoA mutase, chain B [KO:K01849] [EC:5.4.99.2]
SGR_2120  putative isobutyryl-CoA mutase, chain A [KO:K01848] [EC:5.4.99.2]
SGR_1218  putative 3-hydroxyisobutyrate dehydrogenase [KO:K00020] [EC:1.1.1.31]
SGR_1215  putative NAD-dependent aldehyde dehydrogenase [KO:K00140] [EC:1.2.1.18 1.2.1.27]
SGR_4838  putative methylmalonic acid semialdehyde dehydrogenase IolA [KO:K00140] [EC:1.2.1.18 1.2.1.27]
SGR_6067  putative aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
SGR_2630  putative aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
SGR_5794  putative aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
SGR_4071  putative aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
SGR_5177  putative aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
SGR_5088  putative acyl-CoA synthetase [KO:K18662] [EC:6.2.1.-]
SGR_1829  putative 4-aminobutyrate aminotransferase [KO:K07250] [EC:2.6.1.19 2.6.1.22 2.6.1.48]
SGR_4759  putative acetyl/propionyl CoA carboxylase beta subunit [KO:K01969] [EC:6.4.1.4]
SGR_4757  putative hydroxymethylglutaryl-CoA lyase [KO:K01640] [EC:4.1.3.4]
SGR_1191  putative 3-oxoadipate CoA transferase subunit A [KO:K01028] [EC:2.8.3.5]
SGR_1192  putative 3-oxoadipate CoA transferase subunit B [KO:K01029] [EC:2.8.3.5]
SGR_6136  putative AMP-binding protein [KO:K01907] [EC:6.2.1.16]
SGR_2138  putative acetoacetyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
SGR_5170  putative 3-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SGR_4215  putative ketoacyl CoA thiolase [KO:K00626] [EC:2.3.1.9]
SGR_4450  putative thiolase [KO:K00626] [EC:2.3.1.9]
SGR_5494  putative thiolase [KO:K00626] [EC:2.3.1.9]
SGR_6835  putative nonspecific lipid-transfer protein [KO:K00626] [EC:2.3.1.9]
SGR_994  putative acyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
SGR_1380  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Compound
C00024  Acetyl-CoA
C00068  Thiamin diphosphate
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00164  Acetoacetate
C00183  L-Valine
C00233  4-Methyl-2-oxopentanoate
C00332  Acetoacetyl-CoA
C00349  2-Methyl-3-oxopropanoate
C00356  (S)-3-Hydroxy-3-methylglutaryl-CoA
C00407  L-Isoleucine
C00630  2-Methylpropanoyl-CoA
C00671  (S)-3-Methyl-2-oxopentanoic acid
C00683  (S)-Methylmalonyl-CoA
C01205  (R)-3-Amino-2-methylpropanoate
C01213  (R)-Methylmalonyl-CoA
C02170  Methylmalonate
C02939  3-Methylbutanoyl-CoA
C03069  3-Methylcrotonyl-CoA
C03231  3-Methylglutaconyl-CoA
C03284  L-3-Aminoisobutanoate
C03344  2-Methylacetoacetyl-CoA
C03345  2-Methylbut-2-enoyl-CoA
C03460  2-Methylprop-2-enoyl-CoA
C04405  (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA
C05996  Branched chain fatty acid
C05998  3-Hydroxyisovaleryl-CoA
C06000  (S)-3-Hydroxyisobutyryl-CoA
C06001  (S)-3-Hydroxyisobutyrate
C06002  (S)-Methylmalonate semialdehyde
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C15974  3-Methyl-1-hydroxybutyl-ThPP
C15975  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine
C15976  2-Methyl-1-hydroxypropyl-ThPP
C15977  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine
C15978  2-Methyl-1-hydroxybutyl-ThPP
C15979  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine
C15980  (S)-2-Methylbutanoyl-CoA
C20827  3-Hydroxyisovalerate
Related
pathway
sgr00020  Citrate cycle (TCA cycle)
sgr00240  Pyrimidine metabolism
sgr00290  Valine, leucine and isoleucine biosynthesis
sgr00640  Propanoate metabolism
sgr00900  Terpenoid backbone biosynthesis
KO pathway
ko00280   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (49)   
   KEGG GENES (49)   
All databases (50)   

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