KEGG   PATHWAY: sgr00280
Entry
sgr00280                    Pathway                                
Name
Valine, leucine and isoleucine degradation - Streptomyces griseus
Class
Metabolism; Amino acid metabolism
Pathway map
sgr00280  Valine, leucine and isoleucine degradation
sgr00280

Module
sgr_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sgr00280]
Other DBs
GO: 0006550 0006552 0006574
Organism
Streptomyces griseus [GN:sgr]
Gene
SGR_1191  [KO:K01028] [EC:2.8.3.5]
SGR_1192  [KO:K01029] [EC:2.8.3.5]
SGR_1215  [KO:K00140] [EC:1.2.1.18 1.2.1.27]
SGR_1218  [KO:K00020] [EC:1.1.1.31]
SGR_1219  [KO:K01692] [EC:4.2.1.17]
SGR_1380  [KO:K00626] [EC:2.3.1.9]
SGR_1477  [KO:K00632] [EC:2.3.1.16]
SGR_1563  [KO:K00249] [EC:1.3.8.7]
SGR_1829  [KO:K07250] [EC:2.6.1.19 2.6.1.22 2.6.1.48]
SGR_1982  [KO:K00826] [EC:2.6.1.42]
SGR_2087  [KO:K01692] [EC:4.2.1.17]
SGR_2138  [KO:K00626] [EC:2.3.1.9]
SGR_2139  [KO:K05606] [EC:5.1.99.1]
SGR_2616  [KO:K27094]
SGR_2617  [KO:K27095]
SGR_2621  [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
SGR_2630  [KO:K00128] [EC:1.2.1.3]
SGR_3748  bkdA2; putative branched-chain alpha keto acid dehydrogenase E1 alpha subunit [KO:K00166] [EC:1.2.4.4]
SGR_3749  bkdB2; putative branched-chain alpha keto acid dehydrogenase E1 beta subunit [KO:K00167] [EC:1.2.4.4]
SGR_3750  bkdC2; putative dihydrolipoamide acyltransferase component E2 [KO:K09699] [EC:2.3.1.168]
SGR_3765  bkdA1; putative branched-chain alpha keto acid dehydrogenase E1 alpha subunit [KO:K00166] [EC:1.2.4.4]
SGR_3766  bkdB1; putative branched-chain alpha keto acid dehydrogenase E1 beta subunit [KO:K00167] [EC:1.2.4.4]
SGR_3767  bkdC1; putative dihydrolipoamide acyltransferase component [KO:K09699] [EC:2.3.1.168]
SGR_3880  [KO:K00271] [EC:1.4.1.23]
SGR_4071  [KO:K00128] [EC:1.2.1.3]
SGR_4215  [KO:K00626] [EC:2.3.1.9]
SGR_4450  [KO:K00626] [EC:2.3.1.9]
SGR_4756  [KO:K11410] [EC:1.3.8.5]
SGR_4757  [KO:K01640] [EC:4.1.3.4]
SGR_4758  [KO:K01968] [EC:6.4.1.4]
SGR_4759  [KO:K01969] [EC:6.4.1.4]
SGR_4838  [KO:K00140] [EC:1.2.1.18 1.2.1.27]
SGR_5088  [KO:K18661] [EC:6.2.1.76 6.2.1.-]
SGR_5170  [KO:K00632] [EC:2.3.1.16]
SGR_5177  [KO:K00128] [EC:1.2.1.3]
SGR_5204  [KO:K00632] [EC:2.3.1.16]
SGR_5330  [KO:K00382] [EC:1.8.1.4]
SGR_5494  [KO:K00632] [EC:2.3.1.16]
SGR_5794  [KO:K00128] [EC:1.2.1.3]
SGR_5810  [KO:K00249] [EC:1.3.8.7]
SGR_5991  [KO:K00826] [EC:2.6.1.42]
SGR_6067  [KO:K00128] [EC:1.2.1.3]
SGR_6136  [KO:K01907] [EC:6.2.1.16]
SGR_6453  [KO:K00249] [EC:1.3.8.7]
SGR_6745  [KO:K01847] [EC:5.4.99.2]
SGR_6746  [KO:K01847] [EC:5.4.99.2]
SGR_6835  [KO:K00626] [EC:2.3.1.9]
SGR_993  [KO:K01782] [EC:1.1.1.35 4.2.1.17 5.1.2.3]
SGR_994  [KO:K00626] [EC:2.3.1.9]
Compound
C00024  Acetyl-CoA
C00068  Thiamin diphosphate
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00164  Acetoacetate
C00183  L-Valine
C00233  4-Methyl-2-oxopentanoate
C00332  Acetoacetyl-CoA
C00349  2-Methyl-3-oxopropanoate
C00356  (S)-3-Hydroxy-3-methylglutaryl-CoA
C00407  L-Isoleucine
C00630  2-Methylpropanoyl-CoA
C00671  (S)-3-Methyl-2-oxopentanoic acid
C00683  (S)-Methylmalonyl-CoA
C01205  (R)-3-Amino-2-methylpropanoate
C01213  (R)-Methylmalonyl-CoA
C02170  Methylmalonate
C02939  3-Methylbutanoyl-CoA
C03069  3-Methylcrotonyl-CoA
C03231  3-Methylglutaconyl-CoA
C03284  L-3-Aminoisobutanoate
C03344  2-Methylacetoacetyl-CoA
C03345  2-Methylbut-2-enoyl-CoA
C03460  2-Methylprop-2-enoyl-CoA
C04405  (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA
C05996  Branched chain fatty acid
C05998  3-Hydroxyisovaleryl-CoA
C06000  (S)-3-Hydroxyisobutyryl-CoA
C06001  (S)-3-Hydroxyisobutyrate
C06002  (S)-Methylmalonate semialdehyde
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C15974  3-Methyl-1-hydroxybutyl-ThPP
C15975  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine
C15976  2-Methyl-1-hydroxypropyl-ThPP
C15977  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine
C15978  2-Methyl-1-hydroxybutyl-ThPP
C15979  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine
C15980  (S)-2-Methylbutanoyl-CoA
C20827  3-Hydroxyisovalerate
Related
pathway
sgr00020  Citrate cycle (TCA cycle)
sgr00240  Pyrimidine metabolism
sgr00290  Valine, leucine and isoleucine biosynthesis
sgr00640  Propanoate metabolism
sgr00900  Terpenoid backbone biosynthesis
KO pathway
ko00280   

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