KEGG   Sarcophilus harrisii (Tasmanian devil): 100913697
Entry
100913697         CDS       T02286                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04010  MAPK signaling pathway
shr04022  cGMP-PKG signaling pathway
shr04137  Mitophagy - animal
shr04141  Protein processing in endoplasmic reticulum
shr04151  PI3K-Akt signaling pathway
shr04210  Apoptosis
shr04211  Longevity regulating pathway
shr04261  Adrenergic signaling in cardiomyocytes
shr04668  TNF signaling pathway
shr04720  Long-term potentiation
shr04722  Neurotrophin signaling pathway
shr04725  Cholinergic synapse
shr04728  Dopaminergic synapse
shr04911  Insulin secretion
shr04912  GnRH signaling pathway
shr04915  Estrogen signaling pathway
shr04918  Thyroid hormone synthesis
shr04922  Glucagon signaling pathway
shr04925  Aldosterone synthesis and secretion
shr04926  Relaxin signaling pathway
shr04927  Cortisol synthesis and secretion
shr04928  Parathyroid hormone synthesis, secretion and action
shr04932  Non-alcoholic fatty liver disease
shr04934  Cushing syndrome
shr04935  Growth hormone synthesis, secretion and action
shr05010  Alzheimer disease
shr05012  Parkinson disease
shr05014  Amyotrophic lateral sclerosis
shr05020  Prion disease
shr05022  Pathways of neurodegeneration - multiple diseases
shr05030  Cocaine addiction
shr05031  Amphetamine addiction
shr05034  Alcoholism
shr05161  Hepatitis B
shr05163  Human cytomegalovirus infection
shr05166  Human T-cell leukemia virus 1 infection
shr05203  Viral carcinogenesis
shr05207  Chemical carcinogenesis - receptor activation
shr05215  Prostate cancer
shr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:shr00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100913697 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    100913697 (ATF4)
   04022 cGMP-PKG signaling pathway
    100913697 (ATF4)
   04151 PI3K-Akt signaling pathway
    100913697 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    100913697 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    100913697 (ATF4)
   04922 Glucagon signaling pathway
    100913697 (ATF4)
   04915 Estrogen signaling pathway
    100913697 (ATF4)
   04926 Relaxin signaling pathway
    100913697 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    100913697 (ATF4)
   04918 Thyroid hormone synthesis
    100913697 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    100913697 (ATF4)
   04925 Aldosterone synthesis and secretion
    100913697 (ATF4)
   04927 Cortisol synthesis and secretion
    100913697 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    100913697 (ATF4)
   04728 Dopaminergic synapse
    100913697 (ATF4)
   04720 Long-term potentiation
    100913697 (ATF4)
   04722 Neurotrophin signaling pathway
    100913697 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    100913697 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    100913697 (ATF4)
   05203 Viral carcinogenesis
    100913697 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    100913697 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100913697 (ATF4)
   05161 Hepatitis B
    100913697 (ATF4)
   05163 Human cytomegalovirus infection
    100913697 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100913697 (ATF4)
   05012 Parkinson disease
    100913697 (ATF4)
   05014 Amyotrophic lateral sclerosis
    100913697 (ATF4)
   05020 Prion disease
    100913697 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    100913697 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    100913697 (ATF4)
   05031 Amphetamine addiction
    100913697 (ATF4)
   05034 Alcoholism
    100913697 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100913697 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100913697 (ATF4)
   04934 Cushing syndrome
    100913697 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:shr03000]
    100913697 (ATF4)
Transcription factors [BR:shr03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    100913697 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 ZapB Asd-4 bZIP_Maf Laminin_II
Other DBs
NCBI-GeneID: 100913697
NCBI-ProteinID: XP_003771032
Ensembl: ENSSHAG00000014069
Position
5:complement(12050272..12052303)
AA seq 344 aa
MTDMSFLNSDSLWGDLSPFNPSGLGAEEILSPLDDYLEEAKPFKSHGLSSDKAKAVSPDW
LTVDALGPATDYGKEDAFSGMDWMVEKMDLKEFDFDALLGEVLESTCLDLFATLEDSCDL
FGPLATNDKESPSTVNSIGQSPKPLLESDHVASSTSHQSFPLYVRALTSTPDHSFSLDLG
SEVDVLEGDRKSETVYGMMPNGIKEEEAPSDSDSGIGICTSPESYLGSPQHSPSTSTSTL
NESQLSSDPIFISPRPKPYDRPLEDKKEKKVDKKLKKMEQNKTAATRYRQKKRAEQEALS
GECRELEQKNEALKEKADALSKEIQYLKDLIEEVRKAKEKRKNP
NT seq 1035 nt   +upstreamnt  +downstreamnt
atgaccgacatgagcttcctgaacagcgactcgttgtggggggacttgtcccccttcaac
ccgtcgggtttgggggctgaggaaatcctgagccccctcgatgactacctggaggaggcc
aagcccttcaaatcgcatgggctctccagcgacaaggccaaggcagtctctcccgattgg
cttactgtggacgctttaggccccgccacagactacggcaaagaggatgccttctcgggc
atggattggatggtggagaaaatggatctgaaggagtttgatttcgatgccctcttgggt
gaagtcctggaatccacctgccttgatctttttgccacgttggaagactcgtgtgatctg
ttcggccccttggccactaatgataaagagtccccttcaacagttaattcaattggccag
tcccccaaacctctacttgaatctgatcatgttgcctcgagtacctcccatcagtctttt
ccactttatgtaagggccctgacctccacgcctgaccattcatttagtttagatctaggt
agtgaagtggatgtcttggaaggagacagaaaatcggaaaccgtttatggaatgatgcca
aacggtatcaaagaggaagaagccccctcagatagtgatagtggaattggaatctgtaca
agtcccgagtcctacctgggctctccccagcatagcccctccacttccacgagtactctg
aatgagagccagctctcttctgaccctatttttatttctccccgccctaagccttatgac
cgcccccttgaggacaaaaaagaaaaaaaggtagataaaaagttaaagaaaatggaacaa
aacaagactgctgccacacgttataggcagaaaaaacgagcagagcaggaggcattatct
ggggagtgcagagagctagaacagaaaaatgaagctttgaaggagaaggcagatgccctg
agcaaagagatccagtatttgaaagacttgatagaagaggtccgaaaggctaaggaaaaa
aggaaaaatccctaa

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