KEGG   Sarcophilus harrisii (Tasmanian devil): 100934784
Entry
100934784         CDS       T02286                                 
Symbol
IKBKE
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1
  KO
K07211  inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04620  Toll-like receptor signaling pathway
shr04621  NOD-like receptor signaling pathway
shr04622  RIG-I-like receptor signaling pathway
shr04623  Cytosolic DNA-sensing pathway
shr04625  C-type lectin receptor signaling pathway
shr04657  IL-17 signaling pathway
shr04936  Alcoholic liver disease
shr05160  Hepatitis C
shr05161  Hepatitis B
shr05162  Measles
shr05164  Influenza A
shr05165  Human papillomavirus infection
shr05167  Kaposi sarcoma-associated herpesvirus infection
shr05168  Herpes simplex virus 1 infection
shr05169  Epstein-Barr virus infection
shr05171  Coronavirus disease - COVID-19
shr05207  Chemical carcinogenesis - receptor activation
shr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:shr00001]
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100934784 (IKBKE)
   04621 NOD-like receptor signaling pathway
    100934784 (IKBKE)
   04622 RIG-I-like receptor signaling pathway
    100934784 (IKBKE)
   04623 Cytosolic DNA-sensing pathway
    100934784 (IKBKE)
   04625 C-type lectin receptor signaling pathway
    100934784 (IKBKE)
   04657 IL-17 signaling pathway
    100934784 (IKBKE)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    100934784 (IKBKE)
  09172 Infectious disease: viral
   05161 Hepatitis B
    100934784 (IKBKE)
   05160 Hepatitis C
    100934784 (IKBKE)
   05171 Coronavirus disease - COVID-19
    100934784 (IKBKE)
   05164 Influenza A
    100934784 (IKBKE)
   05162 Measles
    100934784 (IKBKE)
   05168 Herpes simplex virus 1 infection
    100934784 (IKBKE)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100934784 (IKBKE)
   05169 Epstein-Barr virus infection
    100934784 (IKBKE)
   05165 Human papillomavirus infection
    100934784 (IKBKE)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100934784 (IKBKE)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100934784 (IKBKE)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:shr01001]
    100934784 (IKBKE)
Enzymes [BR:shr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     100934784 (IKBKE)
Protein kinases [BR:shr01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   100934784 (IKBKE)
SSDB
Motif
Pfam: TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like RH_dom TPR_MLP1_2
Other DBs
NCBI-GeneID: 100934784
NCBI-ProteinID: XP_003767675
Ensembl: ENSSHAG00000017540
Position
4:100653224..100684290
AA seq 780 aa
MVGRCPDFRKIGSNVCSVRTELCDPQKSPLSVHQDFFSLLLKAERTGILQTLEMQSTANY
LWHTDDLLGQGATASVYRARNKKSGELVAVKVFNNASYLRPREVRMREFEVLRKLKHQNI
VKLFAVEEMGGDKEKVLVMEYCSSGSLLSVLENPENTFGLAEAEFLVVLSCVVAGMNHLR
ENGIVHRDIKPGNIMRLLGEDGQSIYKLTDFGAARELEDDEKFVSVYGTEEYLHPDVYER
AVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFVPFGGPRRNKEIMFKITTEKPTGAIA
GTQKRENGPLEWSYKLPITCRLSLGLQAQLVPILANILEVDQEKCWGFDQFFAETSDILQ
RIVVHVFSLSQAVLHHVYIHAHNTIAIFLETVYKQTSVEPSHQGYLFEGHPCLLEPGLPA
QHLAHTTEHSPLILFNENNENPIGLAFRDPSLDVPKFVPKVDLQADYNTAKGVLSVGHQV
LRISRTLLDGQEMMLRGLHWVVEELKTTCGRTLETTQSALLFLSPSLGTEGFTSMTGEEI
PELKEAADLKSKLQTINEILSRCSQNIVETQTSLTSLSSELVKNWDQVHEDRSTHRIQCC
LDKMNVIYKQFKKARMRPGLGYNEEQIHKLDKVNFGHLAKRLLLVFQEDCVQKYQAALLI
HSKRMRTVHETRKHLYLVSSSVATCQKEAQEAQGQLSKVLDRLSRRLWQGRMKAAQSSSP
PFAAYSRPAPKDLVLHIQELREEMKLLAFDLQYNNQIIERLSTDPPTPGSLRAESDVVES
NT seq 2343 nt   +upstreamnt  +downstreamnt
atggtggggagatgcccagattttaggaaaattggttcaaatgtttgctctgttaggact
gagctgtgtgaccctcagaagtcccccctatctgtgcatcaagatttcttctctctcctt
ctaaaagcagaaaggactgggatactgcaaacactggaaatgcaaagcacggccaattac
ctttggcacacggacgatctcctgggccagggtgctactgccagcgtgtacagagctcga
aacaagaaatctggagaacttgttgctgtgaaagtgttcaacaatgccagctacctacgc
ccccgagaagtgcgcatgagggagtttgaagtcctgaggaagctgaaacatcaaaacatc
gtcaagctgttcgcggtagaggagatgggcggcgataaggagaaggtgctggtgatggaa
tactgttccagtggtagcctgctcagtgtgctggagaacccggagaacacctttggctta
gcagaggctgagtttctggtagtcctgagctgtgtggtggccggcatgaaccacctccga
gagaatggcatcgttcacagggacatcaagcctgggaacatcatgagacttttaggagaa
gatggacagagcatctataagctgacagactttggggctgccagggagcttgaagatgat
gaaaagtttgtctctgtctatgggacagaagaatacctgcacccagatgtctatgaacga
gcagtgctccggaaacctcagcagaaggcctttggggtgacggtggatctgtggagcatt
ggggtgactctgtaccacgcagccacaggcagcctcccttttgtcccctttggtgggcct
cgacgcaacaaggagatcatgttcaagatcacgacagaaaaaccaactggggccattgca
ggaacccaaaaacgagagaatggtcccctggagtggagttacaaactgcctatcacctgc
aggctatccttgggattgcaggcccagctggtgcctatccttgccaatatcctggaggtg
gatcaagagaagtgttgggggtttgaccagttcttcgctgagaccagtgacatccttcag
cggatcgtggtccatgtattttctctgtctcaagctgtcctgcaccatgtctacattcat
gcccacaacacgatagccatcttcttggagactgtgtataagcagaccagcgtggagccc
agccaccaggggtacctctttgaaggccatccttgcctcctggagcccggccttcctgcc
caacatctggcccataccacggagcacagccctttgatcctgttcaatgaaaataatgaa
aatcccatcggcctggccttcagagacccatccctggatgttcccaagtttgtgcccaag
gtggacctgcaggctgattacaacacagctaagggtgtgctgagcgtggggcaccaagtg
ctgcgaatctccaggacactgctggacggtcaggaaatgatgcttcgggggctgcattgg
gtggtggaagagctcaagacaacatgtgggcggaccctggagaccactcagtcagctctc
ttgttcctgagccccagtctgggcactgagggcttcacctccatgactggggaggagata
ccagaactgaaggaggcagcagacctgaagtccaagctgcagactattaatgagatcctt
tccagatgttctcaaaatattgtggagactcaaactagtctaactagcctgtcctctgag
ctggtgaagaactgggatcaggtacatgaagacagaagcacccatcgcattcaatgctgc
ctggacaagatgaatgtcatctacaaacaattcaagaaagccaggatgagaccagggttg
ggatacaacgaggaacagatccacaagctggataaggtgaactttggacatttagctaaa
agactccttctggttttccaagaggattgtgtgcagaagtatcaggcagctcttctcatc
cacagcaagaggatgaggacagtgcatgagacaaggaaacatctctaccttgtcagcagc
tcagtagccacttgtcagaaagaagcacaagaagcccaggggcaactcagcaaggtactg
gatcggttatctcgtcggctttggcagggcagaatgaaagctgctcagagttcttctcct
ccttttgctgcttattccagaccagcaccaaaggacctggttcttcacattcaagaactc
cgagaggaaatgaagttactagcctttgatctccaatacaataatcagatcattgagagg
ttaagtacagacccccccacccctgggtctttgagagctgagagtgatgtggtggaatcc
tga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (18)   
   KEGG PATHWAY (18)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (9)   
   RefSeq(pep) (9)   
DNA sequence (9)   
   RefSeq(nuc) (9)   
Protein domain (9)   
   Pfam (9)   
All databases (62)   

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