KEGG   Thermotoga neapolitana: CTN_0116
Entry
CTN_0116          CDS       T00847                                 
Name
(GenBank) putative alpha-isopropylmalate/homocitrate synthase family transferase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
tna  Thermotoga neapolitana
Pathway
tna00290  Valine, leucine and isoleucine biosynthesis
tna00620  Pyruvate metabolism
tna01100  Metabolic pathways
tna01110  Biosynthesis of secondary metabolites
tna01210  2-Oxocarboxylic acid metabolism
tna01230  Biosynthesis of amino acids
Module
tna_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:tna00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    CTN_0116
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    CTN_0116
Enzymes [BR:tna01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     CTN_0116
SSDB
Motif
Pfam: HMGL-like LeuA_dimer SpoIISA_toxin
Other DBs
NCBI-ProteinID: ACM22292
UniProt: B9KB96
Position
complement(106680..108296)
AA seq 538 aa
MSIKIYDTTLRDGAQAFGVSFSLEDKIRIAEALDDLGVHYLEGGWPGSNPKDIAFFEAVK
NMRFKNLKVAAFSSTRRPNTRIEEDPNIQTLIKAETPVYTIFGKSWDLHVEKALRTTLEE
NLKMIYDTITYLKRFADEVIYDAEHFFDGYKANKDYALKTLKVAEEAGADCLVLADTNGG
TLPHEIEEIVEEVKKHVKAPIGIHAHNDSDVAVANTLAAVRKGAVHVQGTINGLGERCGN
ANLCSVIPNLVLKMGLEVIPKENLKKLFDVAHLVAELSGRPHIENMPYVGDYAFAHKGGV
HVSAIKRDPRTYEHIPPELVGNRRIISISELSGKSNVLEKIKEMGFEIDESSPKVREILE
RIKELEAQGYHFEGAEASFELLVREMLGIRRKYFEFLGFTVMTVKNRDEKSFSEATVKVR
VPDEVAERLGHDEPFEHTAAEGEGPVEALDRAVRKALEKFYPSLKNTKLTDYKVRILNEQ
AGTRATTRVLIESSDGKRRWGTVGVSPNIIEASWTALLESLEYKLHRDEEEMRRNEKD
NT seq 1617 nt   +upstreamnt  +downstreamnt
ttgagtatcaagatctacgatacgactctcagggacggggctcaggcttttggagtttcc
ttttccctggaagacaagatcagaatcgccgaggcactcgatgacctcggcgttcactac
ctcgaagggggatggcccggttcgaacccgaaagatattgcattcttcgaagccgtgaag
aacatgcgcttcaagaatttaaaggtggccgctttcagttccacaagaagaccaaacacg
aggatagaagaagatccaaacatacagacgctcataaaagccgaaacaccggtctacacg
atattcggtaaaagttgggatctacacgtggaaaaagcccttcgaacaactctcgaagag
aacctcaagatgatatacgacacgatcacttacctgaaaagattcgccgacgaggtgata
tacgacgctgaacatttcttcgacggttacaaggcaaacaaagactatgccctcaaaacc
ctcaaggtggcagaggaggcgggggcagactgtcttgttcttgccgacacaaacggcggc
acactcccccacgagatcgaagagatcgtagaagaggtgaaaaaacatgtgaaggctccc
ataggaatacacgcacacaacgattccgatgtggccgtagccaacacgctcgctgccgtg
agaaagggagcggtacacgttcagggaaccataaacggccttggcgaaagatgtggcaat
gcgaatctctgttctgtgattccgaacctcgttctcaagatgggacttgaggtcataccg
aaggagaacctgaaaaaactcttcgacgtcgcacatcttgtggccgaactttccggaagg
ccacacattgaaaacatgccctatgtgggagattatgcctttgcacacaaaggtggagtg
cacgtttctgccataaagagagatcccagaacctacgagcacattcctccagaactcgtg
ggaaacaggaggatcatctcgatctccgaactttctggaaaaagcaacgtgcttgagaaa
ataaaagagatgggatttgaaatagacgaatcctcgcccaaggtcagggagatactcgaa
aggataaaagaactcgaagcgcagggatatcatttcgagggtgcagaggcatcctttgaa
cttctcgtcagagagatgcttggaataagaaggaagtatttcgagtttcttggcttcacc
gtcatgaccgtgaagaacagggacgaaaagagtttctcagaagcgaccgtgaaggtaagg
gtacccgatgaagtggcggagaggctggggcacgatgaacccttcgaacacaccgcggca
gagggtgaaggacccgtcgaagcactggacagggcggtgagaaaggcacttgagaagttc
tatccttccctgaaaaacacaaaactcaccgattacaaggtgaggatcctaaacgaacag
gcgggtaccagagcgaccacgagggttctcatagagtccagcgatggaaagagaagatgg
ggaacggtgggtgtttccccgaacatcatagaggcttcctggacggcactgcttgaatcc
ctggagtacaaactccacagggatgaagaggagatgagaagaaatgagaaggattaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (24)   

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