KEGG   Takifugu rubripes (torafugu): 492310
Entry
492310            CDS       T02386                                 
Symbol
cftr
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
  KO
K05031  cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6]
Organism
tru  Takifugu rubripes (torafugu)
Pathway
tru02010  ABC transporters
tru04530  Tight junction
Brite
KEGG Orthology (KO) [BR:tru00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    492310 (cftr)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    492310 (cftr)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:tru02000]
    492310 (cftr)
Enzymes [BR:tru01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.1  Enzymes altering polypeptide conformation or assembly
    5.6.1.6  channel-conductance-controlling ATPase
     492310 (cftr)
Transporters [BR:tru02000]
 ABC transporters, eukaryotic type
  ABCC (CFTR/MRP) subfamily
   ABCC7 subgroup
    492310 (cftr)
SSDB
Motif
Pfam: CFTR_R ABC_membrane ABC_tran SMC_N RsgA_GTPase AAA_21 AAA_29 DUF87 AAA_16 MMR_HSR1 nSTAND3 Dynamin_N Zeta_toxin NTPase_1 nSTAND1
Other DBs
NCBI-GeneID: 492310
NCBI-ProteinID: NP_001041505
Ensembl: ENSTRUG00000017143
UniProt: Q9I8E2
Position
9:13689725..13708673
AA seq 1511 aa
MQKSPVEDANFLSKFFFWWTSPLLRKGFKKKLELSDVYKAPSFDLADNLSERLEREWDRE
IVSAKKRPKLMRALARCFLGPFLFFGILLYLGEASKTVQPQLLGRIIASFDPFHAPERSQ
GYFLALGLCLLFTARFLLLQPAIFGLHHLGMQIRIALFSLIYKKTLKLSSRVLDKISTDQ
LVSLMSAHLNKLDESLGLAHFIWITPLQCILCVGLIWELIEVNGFCALAALTLLGIIQAW
LSQKMGPHRVKRAGMINRRLALTSEIVENIHSVKAYGWEDVMETIIKNIRQDEMTLTRKI
GYLRYFYSAAYFFSAILVIVSAIVPHALSKGIILRRIFTTASYCMVLRMTLTRQLPGSIQ
MWYDTLALVKKIEDFLLKEEYRVLEYNLTTTEVELVNVSASWDEGISELFEKIKQENKAN
GHMANDPGLFFTNLYVTPVLKNISLYLEKGKMLAVAGSTGAGKSSLLMMILGELVPTEGK
IKHSGRISFSPQNSWIMPGTIRDNILFGLTYDEYRYTSVIKACQLEEDFALLPDKDRTLL
MEGGVTLSGGQRARLGLARAVYKDADLYLLDAPFTHLDLVTEREIFEKCVCKLMGSKTRI
VVTSKLEHLKRADKILLLHNGDCYFYGTFLELQAQRPDFSSLLLGLEAYDNINAERRSSV
LTETLRRVSVDETAGFRGPESIRQSFRQPPPPVIVSGSQGNPGGDGYPEKRKQSLILSPL
AAARKFSFMGNSNAGNAAQATATEDGVHEHSERRFSVVPEDDQVEEVLPRSNAYHHGLHH
LSGQRRQSVLAFITTSQGQERRAQIQSSFRKKLSITPQCDLASELDIYARRLSKDSVYDI
SEDVDTEDMEQCFADDRDNTFETTSWSTYLRYVSTNKSLVYVLIFIFVVFVIEVAGSVIG
IFLITDTIWRDGANPSSPNYIDQQHSNTSSPPTHLAVIVTPTSAYYIIYIFVATSESVLA
LGFFRGLPLVHTLLTVSKRLHEQMLSAVLRAPMAVLNTMKTGRIMNRFTKDMATIDDMLP
LVLFDLIQLTLIVTGAIFTVSIMRPYIFIAAIPLAIIFVILRKYFLRTGQQLKLLEAEAR
SPIFSHLIISLKGLWTIRAFGRQTYFETLFHKALNTHTATWFHYLSTLRWFLFRCDIIFV
LFFTAAAFIAVGTNQDKPGEIGIIVALAMLILGTFQWAVITSITVDGLMRSVDRVFKFID
LPSEELLPGKPGGKGRPDLIIDNPHAQDYWPNRGQMDVQGLAVKYTEAGRAVLSDISFSV
EGGLSMGLLGRTGSGKSTLLSALLRLASTDGEISIDGISWNSVPLHKWRKAFGVVPQKVF
ILTGTFRMNLDPHGRYSDEELWRVADQVGLKSVIEQFPDRLDFQLENGGSVLSHGHKQLM
CLARSILSKARILLLDEPSAYLDTITLQVLRKTLKHAFSDCTVILSEHKVEPLLECQSFL
VIEGSSVKSYDSIQKLLNEMSHLKQAVSAADRLRLFPTLHRLNSIKRAPPQAAKISSLPE
EAEDEVHDTRL
NT seq 4536 nt   +upstreamnt  +downstreamnt
atgcagaagtcaccagtggaagatgccaacttcttatccaaatttttcttctggtggacc
tcaccactgctgaggaaaggcttcaagaagaagttggagctctcagatgtttacaaagct
ccttcttttgatcttgcggacaacctctctgaaagacttgaaagagaatgggacagagag
atcgtctcagccaagaagcgacccaagctcatgagagcgctggcccgatgcttcctagga
cctttcctgttctttggcatcctcctctacctcggggaggcttccaagactgtgcaacct
cagcttttgggtcgtatcattgcctctttcgacccctttcatgctccggagcggagccag
ggatacttcctggccctgggcctctgtctcctcttcacggcccgctttctactgctacag
cctgccatctttggcctgcaccacctgggcatgcagatccgcattgccctgttcagcctc
atatataagaagactctgaaactgtccagtcgagtcttggataagatcagcactgatcag
ctggtcagtctgatgtctgcccacctcaacaagctggatgagagcttgggtctggcccac
tttatatggatcacccccttgcagtgtatcctgtgtgtgggtctgatctgggagctgatt
gaggtgaatggcttttgtgcactggctgcgttgactctactgggcatcattcaggcctgg
ctctcacagaagatgggaccacaccgggtgaagagagcaggaatgataaatcggcgcttg
gctctcacctcggagattgtggagaacattcactctgtgaaggcatatgggtgggaggac
gttatggagacgatcatcaagaacatcagacaggatgagatgacactgacgaggaagatc
ggttacttgcgttacttctacagcgctgcctatttcttctctgccatcttggtcatcgtg
tctgccattgtgccacatgcactcagtaaaggcatcatcctgcggcggatcttcaccaca
gcctcgtactgcatggtgctgcggatgaccctgacccgccagctgccagggtccatccag
atgtggtacgacacactggccctggttaagaagatcgaggatttcttgttaaaagaagaa
tacagagtgcttgagtacaacctgaccaccactgaagtggagctggtcaatgtttctgcg
tcctgggatgagggaataagtgaattgtttgagaagatcaagcaggagaacaaagcgaac
ggacacatggccaacgaccccgggctcttcttcaccaacttgtatgtcacaccagttctc
aaaaacatcagcctgtatctggagaagggaaagatgctggcagtggctggatccactggt
gcaggaaagagttccctgctcatgatgatcctgggagaattggtgcctacagaaggtaaa
atcaaacacagtggccgcatctccttctcaccccagaattcctggatcatgccggggacc
atccgagacaacatcctgtttggcctgacctatgacgagtaccgctacacgtctgtgatc
aaggcctgtcagctggaggaggactttgctttgctacctgacaaagacaggacacttctc
atggaaggaggggtgaccctaagcggaggtcaaagggcacgcctgggtttggccagggct
gtctacaaagatgctgacctctacttgctcgatgcaccttttacccacctggaccttgta
acggagagagagatctttgagaagtgtgtgtgtaaactgatgggctccaaaacccgtatt
gtggtcaccagcaagttggagcatctcaagcgggctgacaaaatcctgctcttgcacaat
ggagactgttacttctacggcacgttcttggagctccaggcccagcggcctgacttcagc
tcgctcctcctcggcctggaggcctacgacaacatcaatgcggagcgacgtagctccgtt
ctcacggaaacccttcgcagggtctccgtcgatgaaactgcaggtttccggggtcctgag
tccattcgccagtcattccgtcagccgccacccccagtcattgtatccggatcccaaggc
aatcccggaggtgacggctacccagaaaaacgcaagcagtccctcatcctcagtcccttg
gcagcagctcgaaagttctcttttatggggaactcgaacgcgggaaatgccgcccaggcc
acggcgacagaggatggggtccacgaacattctgagaggaggttctctgtggtgccggag
gacgatcaggtagaggaggtgctcccccgaagcaacgcgtaccatcacgggctgcatcat
ctcagtgggcagaggcgccagtccgtgctggctttcatcaccacgtctcagggccaggag
cgccgagcgcagatacagtcctctttcagaaaaaagctgtccatcacgcctcagtgtgac
ctggcatccgagctggacatctatgctcgacgcctgtccaaggacagcgtctatgatatc
agtgaggatgtggacacggaagatatggagcaatgctttgctgatgatcgtgacaacact
tttgaaactacctcatggagcacgtacctccgctacgtctccaccaacaagagtttggtc
tacgtcctgattttcatatttgttgtcttcgtgattgaggttgctggttcagtcatcggc
attttcttaattaccgacacaatctggagggatggcgccaacccatcatcacccaactac
atagatcagcagcactccaatacttcgtctccgcccacccacctggcagtcatcgtcacg
ccaaccagtgcttactacatcatatacatctttgtggccacgtcggagagcgttctggcc
ttgggattcttcaggggtctcccgttagtgcacacattgctcaccgtgtccaaaaggctt
catgaacagatgctcagcgctgtcctgcgagcccccatggctgtgctcaacactatgaag
acaggccgaatcatgaatagattcaccaaggacatggccaccatcgatgacatgctccct
ctggtgctgtttgaccttattcagctgacactgatcgttacgggggccatcttcactgtg
tccatcatgcggccttacatcttcatcgctgccatccccttggccatcatcttcgtcatt
cttcggaaatacttcctgagaaccggacagcagctcaagctgctggaggctgaagctcga
agtcccatcttctcccacctcatcatctccctgaaggggttatggacaattcgtgcgttt
ggacgccaaacgtactttgagactctcttccataaagcgctgaacactcacacggccacc
tggttccactacctgtccacgctgcgttggtttctttttcgctgtgacatcattttcgtc
cttttcttcactgctgctgccttcatcgccgtaggaaccaaccaggacaaaccaggggag
attggcatcatcgtggccctcgccatgctcatcctggggacgttccaatgggccgtcatc
accagcatcactgtggacggcttaatgcgctcagtcgatcgagtgttcaagttcatcgac
ctcccgtcggaggagctgctgccgggaaaacctggtggtaaaggacgccctgacctcatc
attgacaacccacatgcccaggactactggccaaaccggggccagatggacgtccagggt
ctggcggtgaaatacacggaggcaggtcgcgccgtcctcagtgacatctccttctctgtg
gagggcggtctcagcatggggctgctgggtcgcacgggttcggggaagagcaccctgctc
tcggctctgctgcgtctcgcctccaccgacggcgagatctccatcgacggcatttcctgg
aactccgtccctctgcacaagtggaggaaggccttcggcgtggtgccgcagaaagtcttt
attctaaccggaaccttccgcatgaacctggacccacacggacgttacagcgacgaggag
ctgtggcgggtcgccgatcaggtgggcttgaagtccgtgatcgagcagtttcccgacagg
ctggacttccagctggagaacggaggcagcgtgttgagtcacgggcacaaacagctgatg
tgtctggcccgctccatcctcagcaaggcccgcatcctgctgctggacgagccgtcggcc
tacctcgacaccataacgttgcaggtcctgaggaagaccctcaagcacgccttttctgac
tgcaccgtcatcctgtcggagcataaagtggagccgctgctggagtgccagtccttcctg
gtgattgaaggcagctctgtgaagagctacgactccatccagaagctcctgaacgagatg
agccacctgaaacaggccgtgagcgccgccgaccggctgcggctcttcccgacgctgcac
cgcctcaactctataaagagggcgccgccgcaggccgccaagatctcctccctgccggag
gaagcggaggacgaggtccacgacacgcggctgtaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (15)   
   Pfam (15)   
All databases (43)   

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