KEGG   Tropheryma whipplei TW08/27: TW547
Entry
TW547             CDS       T00117                                 
Symbol
murF
Name
(GenBank) probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
tws  Tropheryma whipplei TW08/27
Pathway
tws00300  Lysine biosynthesis
tws00550  Peptidoglycan biosynthesis
tws01100  Metabolic pathways
tws01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:tws00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    TW547 (murF)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    TW547 (murF)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    TW547 (murF)
Enzymes [BR:tws01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     TW547 (murF)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase Mur_ligase_C CbiA IMP_cyclohyd Hid1
Other DBs
NCBI-ProteinID: CAD67213
Position
complement(583384..584778)
AA seq 464 aa
MLIRRADIQRVTGGILHNTSLSESLLPINGRLKIDSRNISQGDIFVAHTGTKFDGHEFLY
QAKQSGASLAIVTRVQEIDLPQLLVGNVTEAMHAIAGFKLCLSRDTITVIGITGSNGKTT
TKSVLAYVLSKFGNTVATHGNQNNEIGFPITVSRIEPLTKYLVLEYGAFKPGDIDCLKKI
AVPDIAVLLSAGHAHVEKSGSLESVCSMKAELARDLPEGSKVLLNYDDPRIARLSVGNRY
YFGTDKRAHFRASHVETNIIKTRFIVTYQKGSVEVETKLIGKHQVSNVLAALSTLVLLGF
DAEVCARYISEVNPIDGRMQYIPLGDFSIIHDAYNASFESVKCALDSLVVLGSLAKRRIA
VLGRIHDMGELAQDVYRQLVKQFLDTDINLLVIVSEKQMYLIAKELAKGVPNKEIVWFED
LETAKHEIFDLFSPGDIVLFKASNAENFSSLVESVKHKAGKFAG
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgctaatcaggcgtgccgatattcaacgcgtgaccggcggtattttgcacaacacctct
ttatcggaaagtttgttgccaattaacgggcgcctgaagatagattcaaggaatatttca
cagggcgatatttttgttgctcacactggcacaaaattcgacgggcatgagtttttatat
caggcaaagcagtctggtgcaagccttgcaattgtgacgcgtgtacaggaaattgacctt
ccacagttacttgttggcaatgtcacagaagccatgcatgcaattgcaggttttaaacta
tgtctcagcagagatacgattacggtgattgggatcacggggtcgaatggtaagacaaca
accaagagtgttctcgcatatgttctgtcaaaatttggtaatactgtggcaactcatggt
aatcagaataatgaaataggttttccaatcactgtttccagaattgagcctttaacaaaa
tatcttgtccttgaatacggtgcatttaagcctggtgatatagattgtttaaagaagatc
gctgtgcccgatattgcagttctcttatcagcaggccatgctcatgttgagaaaagtggc
agtttagaaagtgtctgttcaatgaaagctgagcttgcgcgcgacctgccagagggatca
aaggtattgctcaattatgatgacccgaggattgccaggctctctgttggaaatcgatat
tattttggaacggataagcgcgcgcattttcgggcgagtcacgtagaaacaaatataatc
aagacgcgtttcattgttacttatcaaaagggtagcgtggaggttgagactaaactgata
ggtaaacaccaggtcagtaatgttctggctgccctgtcgactcttgtgcttttgggattt
gacgctgaggtgtgcgcacggtatatatcagaggttaacccgattgatgggcgtatgcaa
tatattcctctcggagacttttccattattcatgatgcctacaatgcgtcctttgaatcg
gtgaagtgcgctcttgactcgcttgttgttttggggtctctagccaaacggcgtattgct
gttcttgggcgaatacatgatatgggggagctggcacaagatgtgtataggcagcttgtc
aaacagtttttggacacagacattaatcttctggttattgtttcagagaaacagatgtat
ctcatagctaaggaattggccaaaggagtgccaaataaggagattgtgtggtttgaagat
ctggaaacagcaaaacatgagatatttgatttattttctccaggagatatagttcttttc
aaagcctcaaatgcggagaatttttctagcctcgtggagagtgtaaagcacaaagcaggc
aagtttgcgggatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (6)   
   Pfam (6)   
All databases (27)   

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