KEGG   Ursus arctos horribilis (North American brown bear): 113257909
Entry
113257909         CDS       T05909                                 
Symbol
GCK
Name
(RefSeq) glucokinase isoform X1
  KO
K12407  glucokinase [EC:2.7.1.2]
Organism
uah  Ursus arctos horribilis (North American brown bear)
Pathway
uah00010  Glycolysis / Gluconeogenesis
uah00052  Galactose metabolism
uah00500  Starch and sucrose metabolism
uah00520  Amino sugar and nucleotide sugar metabolism
uah00524  Neomycin, kanamycin and gentamicin biosynthesis
uah01100  Metabolic pathways
uah01200  Carbon metabolism
uah01250  Biosynthesis of nucleotide sugars
uah04910  Insulin signaling pathway
uah04911  Insulin secretion
uah04917  Prolactin signaling pathway
uah04922  Glucagon signaling pathway
uah04930  Type II diabetes mellitus
uah04950  Maturity onset diabetes of the young
uah05230  Central carbon metabolism in cancer
Module
uah_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
uah_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
uah_M00892  UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:uah00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    113257909 (GCK)
   00052 Galactose metabolism
    113257909 (GCK)
   00500 Starch and sucrose metabolism
    113257909 (GCK)
   00520 Amino sugar and nucleotide sugar metabolism
    113257909 (GCK)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    113257909 (GCK)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    113257909 (GCK)
   04910 Insulin signaling pathway
    113257909 (GCK)
   04922 Glucagon signaling pathway
    113257909 (GCK)
   04917 Prolactin signaling pathway
    113257909 (GCK)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    113257909 (GCK)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    113257909 (GCK)
   04950 Maturity onset diabetes of the young
    113257909 (GCK)
Enzymes [BR:uah01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     113257909 (GCK)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1
Other DBs
NCBI-GeneID: 113257909
NCBI-ProteinID: XP_026358265
Position
Unknown
AA seq 465 aa
MLDDRARMEVTKKEKAEQILADFQLQEADLKKVMRRMQKEMARGLRLETHEEASVKMLPT
YVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVTTKHQMYSIPEDAMTGTAE
MLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNN
IVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGTGCNACYMEEMQN
VELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQLYEKLIGGKYMGE
LVRLVLLKLVDENLLFRGEASEQLRTRGAFETRFVSQVESDSGDRKQIYNILSTLGLRPS
ATDCDIVRRACESVSTRAAHMCAAGLAGVINRMRESRSEDAMRITVGVDGSVYKLHPSFK
ERFHASVRRLTPSCEITFIESEEGSGRGAALISAVACKKACMLGQ
NT seq 1398 nt   +upstreamnt  +downstreamnt
atgctggatgacagagccaggatggaggtcaccaagaaggaaaaggcggagcagatcctg
gcggacttccagctgcaggaggctgacctgaagaaggtgatgcggcggatgcagaaggag
atggcgcggggcctgcggctggagacccacgaggaggccagcgtgaagatgctgcccacc
tacgtacgctccaccccggagggctcagaagtcggggacttcctctccctggacctgggc
ggcaccaacttcagggtgatgctggtgaaggtgggggagggcgaggaggggcagtggagt
gtgacaaccaagcatcagatgtactccatccccgaggacgccatgactggcaccgctgag
atgctcttcgactacatctctgagtgcatctccgacttcctggacaagcatcagatgaag
cacaagaagctgcccttgggcttcaccttctccttccccgtgaggcatgaagacatagac
aagggcatcctcctcaactggaccaagggcttcaaagcctcgggagcagaagggaacaac
atcgtggggctcctccgtgacgccatcaaacggagaggggactttgaaatggacgtggta
gcgatggtgaacgacacggtggccacgatgatctcctgctactacgaagaccgccggtgt
gaggttggcatgattgtgggcacgggctgtaacgcctgctacatggaggaaatgcagaac
gtggagctcgtggaaggggacgagggccgcatgtgcgtcaacactgagtggggtgccttt
ggggactctggagagctggacgagttcctgctggagtatgaccgcgtggtggatgagaac
tccctgaaccccggccagcagctgtacgagaagctcatcggcggcaagtacatgggcgag
ctggtgcggctcgtgctgctaaaactcgtggacgaaaacctgcttttccgcggggaggcc
tcggaacagctgcgcacgcgcggcgccttcgagacgcgcttcgtgtcgcaggtggagagt
gactcgggcgaccgcaagcagatctacaacatcctgagcacgctagggctgaggccctcg
gccaccgactgcgacatcgtgcgccgcgcctgcgagagcgtgtccacgcgcgccgcgcac
atgtgcgccgcggggctggcgggcgtcatcaaccgcatgcgcgagagccgcagcgaggac
gcgatgcgcatcaccgtgggcgtggacggctcggtgtacaagctgcaccccagcttcaag
gagaggttccacgccagcgtgcgcaggctgacgcccagctgcgagatcacattcatcgag
tcggaggagggcagtggccggggcgcggccctgatctccgcggtggcctgcaagaaggcc
tgcatgctgggccagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (18)   
   KEGG PATHWAY (15)   
   KEGG MODULE (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (40)   

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