ID A0A024GB94_9STRA Unreviewed; 838 AA.
AC A0A024GB94;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=BN9_043910 {ECO:0000313|EMBL:CCI43607.1};
OS Albugo candida.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Albuginales; Albuginaceae; Albugo.
OX NCBI_TaxID=65357 {ECO:0000313|EMBL:CCI43607.1, ECO:0000313|Proteomes:UP000053237};
RN [1] {ECO:0000313|EMBL:CCI43607.1, ECO:0000313|Proteomes:UP000053237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ac Nc2 {ECO:0000313|EMBL:CCI43607.1,
RC ECO:0000313|Proteomes:UP000053237};
RA Gardiner A., Kemen E., Schultz-Larsen T., MacLean D., Van Oosterhout C.,
RA Jones J.D.G.;
RT "Recombination and specialization in a pathogen metapopulation.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX54/DBP10
CC subfamily. {ECO:0000256|ARBA:ARBA00010379}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCI43607.1}.
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DR EMBL; CAIX01000052; CCI43607.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A024GB94; -.
DR STRING; 65357.A0A024GB94; -.
DR InParanoid; A0A024GB94; -.
DR OrthoDB; 5475716at2759; -.
DR Proteomes; UP000053237; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd17959; DEADc_DDX54; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR012541; DBP10_C.
DR InterPro; IPR033517; DDX54/DBP10_DEAD-box_helicase.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR PANTHER; PTHR47959:SF8; RNA HELICASE; 1.
DR Pfam; PF08147; DBP10CT; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM01123; DBP10CT; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053237};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 29..57
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 60..233
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 264..407
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 785..838
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 29..57
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
FT COMPBIAS 1..27
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 785..812
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 813..838
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 838 AA; 94813 MW; 28634D18B6375E38 CRC64;
MASAMPTDDG SNATKAPQNN NSKKNKKGGG FQHLGLSNPV YRAVMAMGYK VPTPIQRKSL
PLILSGKDVV GMARTGSGKS AAFLIPLIEK LKEHSTRVGL RGLVLAPTRE LALQTLQFTK
GLAKYTSLRI SLIVGGEGME QQFSALASNP DILVATPGRL MHHLQEIPDF NLKSVEYVVF
DEADRLFEMG FADQLHEILS QMPLNRQTLL FSATLPSVLA QFARAGLNEP AMIRLDVENK
MSENLKMAFF TVRSDDKPAV FVHLVRDFLP KSDQTIIFTA TRHHVELLHQ LLNANNIESS
CVYGEMDQTS RKLNIAKFRA GKTNLLLVTD VAARGIDIPL LNNVINYSFP PTAKLFVHRV
GRAARAGKSG TAFSLLDPTE YPFLVDLHLY IGRRLEDSSP VNSEPYSLKE MQVQHIHYGS
FPCEITDREN EQIQYLLKHH PIVSPLVKVC DNASKLYQRT RADPSKLSIK RAKGLQIQCH
PLFKKDFLDH DRAEKEECLA KIQTFRPTQT IFEVASSRAV PGTKKSNTTS AMSVMASKRN
AHSKIIEKHA SKDAEVSHIS IPIERYTTPT CFPAQVVAQT EPKKGRYLSK HARKQLRRRV
AAGESQSDVL ENLLAAQDQR NEPTSDTMEI RQTQVKPEFK DQDNYIDTAK SERELMDGSF
FNQVDDQNAF SNRLDASTLD LNPDDALQMN RKRRIVHWDT RKKKYVRTMA QDLTKQGTVR
KKPPAHEYIR TESGIKIKAK KQQWGELYKK WQQKQNRSIR PGLEEDERAG NIDYRHKRVK
LKGVKNELQS EQMIRKEQAR KGRSQSNYKT DKTSHKPRRK GGSHGAPTRS KSIIRKRR
//
