ID A0A026X346_OOCBI Unreviewed; 573 AA.
AC A0A026X346;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=polo kinase {ECO:0000256|ARBA:ARBA00012424};
DE EC=2.7.11.21 {ECO:0000256|ARBA:ARBA00012424};
GN ORFNames=X777_07487 {ECO:0000313|EMBL:EZA62672.1};
OS Ooceraea biroi (Clonal raider ant) (Cerapachys biroi).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Dorylinae; Ooceraea.
OX NCBI_TaxID=2015173 {ECO:0000313|EMBL:EZA62672.1, ECO:0000313|Proteomes:UP000053097};
RN [1] {ECO:0000313|EMBL:EZA62672.1, ECO:0000313|Proteomes:UP000053097}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24508170; DOI=10.1016/j.cub.2014.01.018;
RA Oxley P.R., Ji L., Fetter-Pruneda I., McKenzie S.K., Li C., Hu H.,
RA Zhang G., Kronauer D.J.;
RT "The genome of the clonal raider ant Cerapachys biroi.";
RL Curr. Biol. 24:451-458(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000540};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.21; Evidence={ECO:0000256|ARBA:ARBA00000856};
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DR EMBL; KK107019; EZA62672.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A026X346; -.
DR STRING; 2015173.A0A026X346; -.
DR EnsemblMetazoa; XM_011353414.2; XP_011351716.1; LOC105287695.
DR EnsemblMetazoa; XM_026971356.1; XP_026827157.1; LOC105287695.
DR OMA; IQIHKSM; -.
DR OrthoDB; 5471704at2759; -.
DR Proteomes; UP000053097; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd13118; POLO_box_1; 1.
DR CDD; cd13117; POLO_box_2; 1.
DR CDD; cd14099; STKc_PLK; 1.
DR Gene3D; 3.30.1120.30; POLO box domain; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR033701; POLO_box_1.
DR InterPro; IPR033695; POLO_box_2.
DR InterPro; IPR000959; POLO_box_dom.
DR InterPro; IPR036947; POLO_box_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR24345; SERINE/THREONINE-PROTEIN KINASE PLK; 1.
DR PANTHER; PTHR24345:SF0; SERINE_THREONINE-PROTEIN KINASE PLK1; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF00659; POLO_box; 2.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF82615; Polo-box domain; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50078; POLO_BOX; 2.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EZA62672.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053097};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 22..274
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 394..457
FT /note="POLO box"
FT /evidence="ECO:0000259|PROSITE:PS50078"
FT DOMAIN 492..560
FT /note="POLO box"
FT /evidence="ECO:0000259|PROSITE:PS50078"
SQ SEQUENCE 573 AA; 65501 MW; 2588C0FF7476C2E7 CRC64;
MSKDEECTIP GVIYDAKTGK SYMKGRFFGK GGFAKCYEIT ESKTHQVFAG KIVPKSLMTK
SNQREKMLQE ITIHQTLNHR HIVGFHGSFD DSHNIYIILE LCRKRSMMEL HKRRKALSEC
ETRYFMKQIL DGVFYLHQHK IIHRDLKLGN LFLNDELQVK IGDFGLATRL EHEGERKKTV
CGTPNYIAPE VLTKIGHSFE ADVWSIGCIM YTLLVGKPPF ETASLRETYA RIKQVQYKTP
THIGKPAMNM VSNMLQLNPS KRPSVPRLMK DVFFTSGYMP TSLPLSCLTM PPRLDMLESH
CNRKPLGEMN LNGFSEQDII ACRVPNSPRK VKPAAEITDT QRASFDIKMM LCTLKEQLAA
VLKTKPARET ASLADEMTDP AAQPVVWISK WVDYSDKYGF GYQLSDDGVG VMYNDGTRLI
MLANGFNIHY INREGDELYY TVKEYPSNLE KKMKLMNFFL KYMNEHLMKA GGSIAVKQSD
SLSRIPYIHQ WFRTQTAVVM QLTNGTVQIN FLDHTKIIIC PLMAAVTYID HDKNFKTYRF
QTIQESGCCK GLAKNLAYAY EKIGLMLSNP QAR
//
