ID A0A061EGF4_THECC Unreviewed; 1109 AA.
AC A0A061EGF4;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN ORFNames=TCM_011292 {ECO:0000313|EMBL:EOY01384.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY01384.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOY01384.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
CC -!- FUNCTION: Probably involved in the RNA silencing pathway and required
CC for the generation of small interfering RNAs (siRNAs).
CC {ECO:0000256|RuleBase:RU363098}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC ECO:0000256|RuleBase:RU363098};
CC -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC ECO:0000256|RuleBase:RU363098}.
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DR EMBL; CM001880; EOY01384.1; -; Genomic_DNA.
DR EMBL; CM001880; EOY01385.1; -; Genomic_DNA.
DR EMBL; CM001880; EOY01386.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061EGF4; -.
DR STRING; 3641.A0A061EGF4; -.
DR EnsemblPlants; EOY01384; EOY01384; TCM_011292.
DR EnsemblPlants; EOY01385; EOY01385; TCM_011292.
DR EnsemblPlants; EOY01386; EOY01386; TCM_011292.
DR Gramene; EOY01384; EOY01384; TCM_011292.
DR Gramene; EOY01385; EOY01385; TCM_011292.
DR Gramene; EOY01386; EOY01386; TCM_011292.
DR eggNOG; KOG0988; Eukaryota.
DR HOGENOM; CLU_001366_3_0_1; -.
DR InParanoid; A0A061EGF4; -.
DR OMA; CYNEGYE; -.
DR Proteomes; UP000026915; Chromosome 2.
DR GO; GO:0031380; C:nuclear RNA-directed RNA polymerase complex; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IBA:GO_Central.
DR GO; GO:0030422; P:siRNA processing; IBA:GO_Central.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR PANTHER; PTHR23079:SF55; RNA-DIRECTED RNA POLYMERASE; 1.
DR Pfam; PF05183; RdRP; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000256|RuleBase:RU363098};
KW RNA-mediated gene silencing {ECO:0000256|RuleBase:RU363098};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
SQ SEQUENCE 1109 AA; 127178 MW; 9C3B9DC920523B66 CRC64;
MGKTIQVSRF PSNVHAEEVK TFLELYTGKE TVYALKIRQQ KNGGRAYAIV QFTKSTDAEL
IIRLTNQRLY YGSSYLKARE MENDIVPKPR TFLHTMEGVT LHFGCQVSNE KFYVLWEEVD
VTVNFGMGMR KLQFLLSHHC VEYRLDLFYE NIWQIELHRP RNQTSKYLLI QLFGAPRIYE
KDVRSSGLVF ENPLLNYFMD VPDDQWVRTT DFTQSSCIGQ SSVLCLELPY YLQLPNFREN
FAYYKESEGK FVLESGSSYS RNLNLVPIVG PSLGIDLPYE ILFKINLLVQ NGCIPGPALD
ANFYRLVNPC RIDKVYIDHA LEKLYYLKEC CFEPSKWLLE QYKGYIASKK NPGSPVISLD
DGLVNVRRVQ ITPSRVYFCG PEINVSNRVL RHFHDDIDNF LRITFVDEEL EKIHSTDLLT
RNRITEIYGR ILSTLKNGIV IGDKQFEFLA FSSSQLRENS AWMFASREGL TAADIRTWMG
EFSKIRNVAK YAARLGQSFS SSTETLSVAK DEIEIIDDVE IKRDGINYVF SDGIGKISAK
FAKKVAAKCR LNGRTPSAFQ IRIGGFKGVV AVDPTSSKKL SLRGSMSKYE SENTKLDVLA
WSKYQPCFLN RQLITLLSTL GVPDHAFEEK QREVVDQLNA ILTDPLKAQE ALELMSPGEN
TNILKEMLLC GYEPDAEPFL SMMLQTFRAS KLLELRTKSR IFVANGRSMM GCLDETRTLD
YGQVFVQVSG SRSEQRFIVQ GKVVVAKNPC LHPGDVRVLT AVNVPDLHHM VDCVVFPQKG
SRPHPNECSG SDLDGDIYFV CWDPELIPSK QIPPMDYSPA PTKPLEHEVT IEEVEEYFTN
YIVNDSLGII ANAHTVFADR EPRKAMSSEC KWLAKLFSIA VDFPKTGVPA EIPQELRVKE
YPDFMEKPDK PTYQSYNVIG KLFREVKDLA PNECFIRSLT RERLERFYDP DMEVDGYEDY
VDDAFYHKSN YDYKLGNLME YYGIKTEAEI LSGGIMKMSR SFTKQRDAEA IGVAVRSLRK
EARSWFNEKG NGLDSEADDL YAKASAWYHV TYHPSYWGLY NEGMNRNHFL SFPWCVYDKL
ILIKKKVTSR RNSRLSSLES LFARGLRLH
//
