ID   A0A067GAG9_CITSI        Unreviewed;       177 AA.
AC   A0A067GAG9;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=cysteine dioxygenase {ECO:0000256|ARBA:ARBA00013133};
DE            EC=1.13.11.20 {ECO:0000256|ARBA:ARBA00013133};
GN   ORFNames=CISIN_1g023638mg {ECO:0000313|EMBL:KDO72507.1};
OS   Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO72507.1, ECO:0000313|Proteomes:UP000027120};
RN   [1] {ECO:0000313|EMBL:KDO72507.1, ECO:0000313|Proteomes:UP000027120}
RP   NUCLEOTIDE SEQUENCE.
RG   International Citrus Genome Consortium;
RA   Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA   Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA   Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-cysteine + O2 = 3-sulfino-L-alanine + H(+);
CC         Xref=Rhea:RHEA:20441, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379,
CC         ChEBI:CHEBI:35235, ChEBI:CHEBI:61085; EC=1.13.11.20;
CC         Evidence={ECO:0000256|ARBA:ARBA00024284};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:20442;
CC         Evidence={ECO:0000256|ARBA:ARBA00024284};
CC   -!- COFACTOR:
CC       Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC         Evidence={ECO:0000256|ARBA:ARBA00001954};
CC   -!- SIMILARITY: Belongs to the cysteine dioxygenase family.
CC       {ECO:0000256|ARBA:ARBA00006622}.
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DR   EMBL; KK784887; KDO72507.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A067GAG9; -.
DR   Proteomes; UP000027120; Unassembled WGS sequence.
DR   GO; GO:0017172; F:cysteine dioxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0070483; P:detection of hypoxia; IEA:UniProt.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR   InterPro; IPR012864; PCO/ADO.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   PANTHER; PTHR22966:SF1; PLANT CYSTEINE OXIDASE 2; 1.
DR   PANTHER; PTHR22966; UNCHARACTERIZED; 1.
DR   Pfam; PF07847; PCO_ADO; 1.
DR   SUPFAM; SSF51182; RmlC-like cupins; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027120}.
FT   REGION          135..177
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        138..177
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   177 AA;  18570 MW;  1BD450DC879202B7 CRC64;
     MPEQPYFRRQ AGRKYPAITY QHIFECEKFS MGIFCLPPSG VIPLHNHPGM TVFSKLLFGT
     MHIKSYDWVV DVPSDTSADA AGVPGKTSAV AVDAIPGETS AAAVDIIPGK PLAAMVDVIP
     GKPLAAAVDA VPDKNSADVV NDNGNTSADA VDVPSKMSTD ANPSESNQEA WSAVGKS
//