ID A0A067R0H6_ZOONE Unreviewed; 1900 AA.
AC A0A067R0H6;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=L798_09659 {ECO:0000313|EMBL:KDR16241.1};
OS Zootermopsis nevadensis (Dampwood termite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Termitoidae;
OC Termopsidae; Zootermopsis.
OX NCBI_TaxID=136037 {ECO:0000313|EMBL:KDR16241.1, ECO:0000313|Proteomes:UP000027135};
RN [1] {ECO:0000313|EMBL:KDR16241.1, ECO:0000313|Proteomes:UP000027135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole organism {ECO:0000313|EMBL:KDR16241.1};
RX PubMed=24845553; DOI=10.1038/ncomms4636;
RA Terrapon N., Li C., Robertson H.M., Ji L., Meng X., Booth W., Chen Z.,
RA Childers C.P., Glastad K.M., Gokhale K., Gowin J., Gronenberg W.,
RA Hermansen R.A., Hu H., Hunt B.G., Huylmans A.K., Khalil S.M.,
RA Mitchell R.D., Munoz-Torres M.C., Mustard J.A., Pan H., Reese J.T.,
RA Scharf M.E., Sun F., Vogel H., Xiao J., Yang W., Yang Z., Yang Z., Zhou J.,
RA Zhu J., Brent C.S., Elsik C.G., Goodisman M.A., Liberles D.A., Roe R.M.,
RA Vargo E.L., Vilcinskas A., Wang J., Bornberg-Bauer E., Korb J., Zhang G.,
RA Liebig J.;
RT "Molecular traces of alternative social organization in a termite genome.";
RL Nat. Commun. 5:3636-3636(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR EMBL; KK852804; KDR16241.1; -; Genomic_DNA.
DR STRING; 136037.A0A067R0H6; -.
DR EnsemblMetazoa; KDR16241; KDR16241; L798_09659.
DR eggNOG; KOG0334; Eukaryota.
DR eggNOG; KOG2279; Eukaryota.
DR InParanoid; A0A067R0H6; -.
DR OMA; KCFFVDQ; -.
DR OrthoDB; 2958343at2759; -.
DR Proteomes; UP000027135; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR CDD; cd20435; Tudor_TDRD12_rpt2; 1.
DR Gene3D; 2.30.30.140; -; 3.
DR Gene3D; 2.40.50.90; -; 2.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR002999; Tudor.
DR PANTHER; PTHR22655:SF2; ATP-DEPENDENT RNA HELICASE TDRD12-RELATED; 1.
DR PANTHER; PTHR22655; UNCHARACTERIZED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00567; TUDOR; 3.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00333; TUDOR; 3.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 3.
DR PROSITE; PS51203; CS; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS50304; TUDOR; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000027135};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-mediated gene silencing {ECO:0000256|ARBA:ARBA00023158};
KW Spermatogenesis {ECO:0000256|ARBA:ARBA00022871}.
FT DOMAIN 66..128
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT DOMAIN 689..904
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1432..1491
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT DOMAIN 1718..1805
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT REGION 1869..1900
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1871..1891
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1900 AA; 214156 MW; 5A634AAA9CD74CD1 CRC64;
MAEDDTLPAN AVIVSVMHMV DPSTLWVTES PQKDMSKDRE ELIHLEEMLS GHCRRSSYNF
QGMNYLPEEG ELVAVQNPET GHWHRAQVDY VLHVTNGYIY KVFLVDHGLP FEVRSSSIRK
LPAAWNNFDF QAFQVVLYGI IPTTVGMDYQ DMKMKREVAS NWSAAAVKFV KRLLEESTKS
WLVYKKNVKK KIYGDLFLEL SNGSISLSKE LCSQEYAVFS EALFEEALIK SDTKQEEFVY
RTPSPQVPVC TDSRNQNTSP VPSLSNKIEH RQIRDYIREC SVKRAKIEEQ KCNQTDKWRR
DVEAASVDTH EDGECFQSYG KQPLGRGMSI LSRKEISPGV RSKLTPASVE QVGKWNEVSS
SEISHEHEIK SSSLLGLLDL IDFNSDHDSI SVSELNNASH KSLFSHEKNS SFTEYIPAGG
DLETFNKRSK NQRDFNSSSV INRGRCSIDV ENNSHSPSFK DPKKYDSVPD MLPQSISLHT
ERNEVQSSVV IHSEYGEEIG VKKQQRSLSL LKCVQTETNS AIKNSDNKTE NVGGIQCDIK
QKDITSVSTT SFFQDIVNSM ERTAQSKRQN LLDNLKKNAQ SVSSIPDVTA KLPQAALTAV
LKRETSGNDT QIKSNSLASV ETLPSVQIET LSTAYKITDR LQTSRILVHG DMCFRTIQSI
AEANFPMEIH QALAKMDFKA PMRIQTYVWP AIMRGQYTVL VGPPRSGKTV AYLIPLVSFM
LTPDVYSDLP PGNGPLVLVL CSGSRSAQFV YEKCCTLLEL SNQNKVRVEI AYGGDRERDL
EVFLANGCDI LISTPRCFMR LLRCSRFITN MERLAHLVLD GVDILAEKFL PELKELIAEC
KKMLERRSKV EMPVQVIATS EKWCPAVEQF SQHISQNFLV CISGYLEAAV YAKLKPTLHF
LSASSRPQVV LDILDGYQGL YKTVIVCQSV AEVSDLVQVL ESQCYQVLAA HEDMTQCHNS
EICYHWKCSV SGVHPVLVCT DEVLHELDVC DAMWLIHYSL PHTKTGFGFR FSCLMDNYNS
VFKKSTSKND SSGCKVHIFA DKDQTTRALP EVLHFLKRLS VPIAPDIEAK ALEIVRQKES
QKCSFPLCYY VKAFGECKER MCRSRHIILD AVDRPSSIPT CGHVKVKILH VHNASSFSAR
LLEHTDVHGC TVPIPDEYLA VNMAVYMHYS NESNRQLHGV PKLGDVCALE SKINFFQRVQ
VVEVVKEDSK HFPEVLKVKF VDEGTFSVVK VYQLLAMPAD LQRLPPQVID IFLCNVLPCD
LDTDWSKTAN CRMKDWINDT NSGEEDGKFI VGKVMLSAGH TLWLDPLECR SYLSRLDTHV
LELSLGKKLV KCGLAVKNPS HLNKLYELCL AGGLSVPSYE KVPASKNVQT KIQTLPSPQW
AQPDTEIFEE ISIIHAHNPH QLFIQRCKFS DSLERLIDEL QKCVKTKPED FHLEKGTYCL
GKFPDDGLWY RARADQLLEG DRALLFFVDH GDNASVSIDD IAPITEMLIK QLPFQAIECS
LAGVKPLDED TWSDEATDML YEFNNNSSCL FCKVCDVMKT AVCTGGGKYK VVLMDTSTEV
DIYLNRVLLE RNLALPDNIE QIFENLDLVR SKQADSSEES GVEIEKSQLI DLSGISISQH
SKTNAIIPSG EESILDTNYD DDDDDDEYDN MYDNDDIQKL LIEILGLNTN CEPSMTALPA
LPSSHDHSTD NAAYSSSNYF SSDDDNDTDC MFPLVRSTRT PQVLWHQNDS TIYVTIMITG
VLKYHIKWNV THLQFSTNVN GQVYEVTLDL YGPVNASSMT HIAKGFFVHI KMMKTVIGFD
WPRLLSSHYK QPWLKLDLEK YINDSDSEDV TAKSVCSKAL KQLLLPNKEV QIADTGLIAR
ANVARIPVSN FDDDDDDDDD VDDDDDSDVM ETSYPYDSLN
//
