ID A0A0D2QA58_GOSRA Unreviewed; 1469 AA.
AC A0A0D2QA58;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=B456_002G216000 {ECO:0000313|EMBL:KJB16164.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB16164.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB16164.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR EMBL; CM001741; KJB16164.1; -; Genomic_DNA.
DR EnsemblPlants; KJB16164; KJB16164; B456_002G216000.
DR Gramene; KJB16164; KJB16164; B456_002G216000.
DR Proteomes; UP000032304; Chromosome 2.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd00048; DSRM_SF; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF145; ATP-DEPENDENT RNA HELICASE DHX29; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304}.
FT DOMAIN 637..813
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 913..1088
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 203..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 597..624
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 12..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..76
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..223
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1469 AA; 163729 MW; F5F058F569EE1FDC CRC64;
MAPKKKPQKQ SNRKATSASS SSSKANQATS SAPRLQISAE NENRLRRLLL NSGHSTQSQS
QSQSESDLNP PQDSLSKAQK AKKLKALYEK LSCEGFSNDQ IELALSSLKD GATFETALDW
LCLNLPRNEL PLKFSSGISL HSDGGGSISV ISVEREDWTP SVDASTRIKE NLHGLSVRTK
SSEDENSLNM CQPSQADWIR QYMEQQEEDE SKTWEDEASD EGSAEEVSGP RPYDVIAKEY
HAARLEATKA KEKKDKNGQE KAGSRIRKLK QELSALGLSD AVLASDFLHE RASASVSEGT
VTSSMPEEQP EMISLGDAEC NSAACVITSG VATGSVNDTE TSKELSTKSI PSLLPTQEKG
DAENMSEDLE IGDFFLEDSS INDVLASEVL KLRKQEKMKE LYSEKNLEKL DGIWKKGESK
KIPKAVLHQL CQRSGWEAPK FDKMPAKGKS FAYSVSVLRK ASGRGKSRKA GGLITLQLPN
EQEAFESAED SQNRVAAFAL CQLFPDLPTQ LIVTEPYSSL IFQWKGGESL TKIEDNEEDR
RAGFVDRLLR DEDSRSKAPG HDTNESALNE FQKACLEDNK TSSSSVADPV YERKSHAKEM
ESVYLRQEEE KRKHTQRYKM LKTRAALPVA GLKNDILQLL KENNVLVVCG ETGSGKTTQV
PQFILDDMIE SGHGGHCSII CTQPRRIAAI SVAERVADER CEPSPGSNWS LVGYQVRLDN
ARNEKTKLLF CTTGILLRKL AGDKNLTGVT HIIVDEVHER SLLGDFLLIV LKNLIEKQSV
SNTPKLKVIL MSATVDSDLF SRYFGLCPVI TAQGRTHPVT TCFLEDIYER INYHLASDSP
ASLRCETSTR DMRGPVNNHR GKKNLVLSAW GDDSLLSEEY VNPHYDSSSY QSYSEQTQQN
LKRLNEDVID YDLLEDLVCH VDETCDKGAI LIFLPGVVEI HTLLDRLAAS YRFAGPSSDW
LLPLHSSIAA DEQKKVFLNP PDGIRKVIIA TNIAETSITI DDVVYVIDCG KHKENRYNPQ
KKLSSMVEDW ISRANAKQRR GRAGRVKPGI CFCLYTRHRF EKLMRPYQVP EMLRMPLVEL
CLQIKLLSLG QIKPFLSKAL EPPKEEAMNS AISLLYEVGA VEGDEELTPL GHHLAKLPVD
VLIGKMLLYG GIFGCLSPIL SISACLSYKS PFLYPKDEKQ NVERAKLALL SEKLDESSDL
NDAERQSDHL LMMAAYRKWE KIFREKGVKA AQRFCKMYFL SSSVMSMIRD MRIQFGTLLA
DIGFINLPKN YKSGGKRKEN LDGWFSDYSQ PFNIHSHHSA VVKAILCAGL YPNVAATELG
ITGVALSRLK LNPATKGHPV WYDGRREVHI HPSSINSSLK SFQHLFLVFL EKVETNKVFL
RDTTIISPFS ILLFGGLINI QHQSGLVVID GWLKLTAPAQ TAVLCKELRS ALHSILKELI
RKPENATIVD NEVVKSMIHL LLEEDKPSK
//
