ID A0A0D2UH40_GOSRA Unreviewed; 1196 AA.
AC A0A0D2UH40;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN ORFNames=B456_009G057700 {ECO:0000313|EMBL:KJB55000.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB55000.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB55000.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC -!- FUNCTION: Probably involved in the RNA silencing pathway and required
CC for the generation of small interfering RNAs (siRNAs).
CC {ECO:0000256|RuleBase:RU363098}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC ECO:0000256|RuleBase:RU363098};
CC -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC ECO:0000256|RuleBase:RU363098}.
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DR EMBL; CM001748; KJB55000.1; -; Genomic_DNA.
DR RefSeq; XP_012442341.1; XM_012586887.1.
DR RefSeq; XP_012442342.1; XM_012586888.1.
DR AlphaFoldDB; A0A0D2UH40; -.
DR STRING; 29730.A0A0D2UH40; -.
DR EnsemblPlants; KJB55000; KJB55000; B456_009G057700.
DR GeneID; 105767380; -.
DR Gramene; KJB55000; KJB55000; B456_009G057700.
DR KEGG; gra:105767380; -.
DR eggNOG; KOG0988; Eukaryota.
DR OMA; HPKWVKK; -.
DR OrthoDB; 5477883at2759; -.
DR Proteomes; UP000032304; Chromosome 9.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProtKB-KW.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR PANTHER; PTHR23079:SF18; RNA-DEPENDENT RNA POLYMERASE 6; 1.
DR Pfam; PF05183; RdRP; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000256|RuleBase:RU363098};
KW RNA-mediated gene silencing {ECO:0000256|RuleBase:RU363098};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
SQ SEQUENCE 1196 AA; 136730 MW; 7667147BB9DA927C CRC64;
MELEGSVKET VVTQVSVGGF DRHVKARDLM KYLENAVGVV WRCRLKTSWT PPESYPNFEI
TDTSVIQRKD NYKKVEPHAF VHFASPEAVT WAVDAAGRTE LAFNNQLLKV SLGPENPYYL
NRRRRDTAPF MLPDVSLEIG ALASCDEFFV GWRGPPSGVE FLVDPFDCTC KFCFSRDTAF
SFKGTNERAV IKCDFKVEFL VREINEVKQY SEQTGFVVLL QLASSPWVWY RTADDDFEKS
VPFDLLDDDD QWIRTTDFTA SGAIGRCNTY RVLVRPRHGL KLKKAMYYLR ERRVPVKDLR
SQLRICDEPY FGRSMSDHFY YTYKEGIPFE IMFLVNAVLH KGIFNQHQLS MDFFKLLRNQ
SMEVNVAALR HIYSSRHPVY DAYKRLKDVH DWLLKNPKLF RSPPQLDDIV EIRRLVITPT
KAYCLLPEVE LSNRVLRKYK DVADRFLRVT FMDEGMQTMN ANVLTYYNAA IVRDVTSTSF
SQKTGVFKRV KSILTDGFYL CGRKYSFLAF SANQLRDRSA WFFAEDGKIN VLQIIGWMGK
FANRNIAKCA ARMGQCFSST YATVEVPSGQ VNMHLPDIQR NGYDFSDGIG KITPDLAMEV
AQKLKLDLNP PCAYQIRYAG CKGVVACWPE EGDGIRLSLR SSMIKFFSHH TTLEICSWTR
FQPGFLNRQI ITLLSTLGVP DKVFWGMQKS MVSKLDKVLV DTDAAFEVVI SSCGEQGHTP
AIMLSAGFKP QTEPHLRGML TCVRASQLWG LREKSRIFIH SGRWLMGVLD ELGVLEQGQC
FIQVSNPSLQ NCFLKHGSRF AETKKNFEVI KGLVVIAKNP CLHPGDVRIL EAVDAPGLHH
LYDCLVFPQK GERPHTNEAS GSDLDGDLYF VTWEEALIPP SKKSSQPMQY NPDEPRELHR
PVTHKDIIEF FSKNMVNEHL GSICNAHVVH SDLSDHGASD EKCIHLAELA AIAVDFPKTG
KIVSMPAHLK PQLYPDFMGK EEFQSYKSNK ILGRLYRDIK DAYDEDVSES SGLNFCASDI
NYDADLEITG SADYIADAWA KKCSYDGQLI GLLKQYKVKR EEEVVTGQIW SMPKYASKKL
GDLKEKLGHS YGSLRKEFRQ LFENMDSDFE QLNEDEKNKL YERKASAWYQ VTYHPEWVQK
TLEFQKPDGD EGVVMLSFAW IAADYLARIK VRHQGTENLD FAKPVNSLVR YLADRI
//
