ID   A0A0F4ZCJ1_9PEZI        Unreviewed;      1454 AA.
AC   A0A0F4ZCJ1;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE            EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN   ORFNames=TD95_001211 {ECO:0000313|EMBL:KKA27940.1};
OS   Thielaviopsis punctulata.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Microascales; Ceratocystidaceae; Thielaviopsis.
OX   NCBI_TaxID=72032 {ECO:0000313|EMBL:KKA27940.1, ECO:0000313|Proteomes:UP000033483};
RN   [1] {ECO:0000313|EMBL:KKA27940.1, ECO:0000313|Proteomes:UP000033483}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CR-DP1 {ECO:0000313|EMBL:KKA27940.1};
RA   Radwan O., Al-Naeli F.A., Rendon G.A., Fields C.;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC         ECO:0000256|RuleBase:RU363098};
CC   -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC       ECO:0000256|RuleBase:RU363098}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKA27940.1}.
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DR   EMBL; LAEV01001486; KKA27940.1; -; Genomic_DNA.
DR   OrthoDB; 5477883at2759; -.
DR   Proteomes; UP000033483; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR   InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR   PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   PANTHER; PTHR23079:SF55; RNA-DIRECTED RNA POLYMERASE; 1.
DR   Pfam; PF05183; RdRP; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033483};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000256|RuleBase:RU363098};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1239..1272
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1454 AA;  163399 MW;  15F393D21A587460 CRC64;
     MTRSKRGKGR QPPPATEPSY PTVRVTPAVS LAPKRSAGWK SWEGAEILLV GLPPHTAPKD
     VYSFVRKHGG EISRIEIQKV QAIESDADQR RINVTQASVF YTRLPDIAFW SAGRIFFRER
     ERCWTVAISA FENKMTVSRI KSPATPNVTY PACIDFVPQK MGFGILTHAD TVMLMKEIVS
     DPTDGESFQK IEVDIRRRQI RVFFGIPRTW TNMASRCFKC VVDFDNLRAI YLDGFTPSQP
     HGTLRVSMLY PPPYYWKRLD KPSAFTPNTN TFDVQNAWMR VCSIGEDHRE PHHLCYHNSS
     KGSAFIDFGR WKTLLISISQ IPREEETLNA LRDFSMPLVR EPSPLRVVPG SINPVWEEID
     RSPSTPNNLT MLSMVAKAPQ RLPWTVRYQL EVCLTKGVFE EHSINADFIN VLAEMGEVEA
     LSLLERAADH SNRSDVPKDQ ILIPDPMAIL QPNNTILKGC RFTTRPRIPH YCALVRKAIV
     TPTTVYFHTP TIESTNRVLR KFRHVQDHFL RVQFSDELLN GKLSSGNTGN RFDNVYYRVY
     NVMDEGIRIG ERVFKYLACG NSQMRECGAY FFADTPEVTR DDIRAWMGNF EDIRSVAKRA
     ARIGQCFSTT RAVRGVSVPS IKRIPDIEKG KYCFTDGVGK ISRPLASLVM EEMELFTAPG
     EPVPAAYQFR MGGCKGVLVV SDDANGMEVH IRKSQEKFQS DFNALEIIRV SQYSIATLNR
     QTIVVLSSLG VPDEVFMELL NDQLLSYEKA MVDIPTAMTL LTQYIDENAI SLQLAEMVRA
     GFMNKGQEEP FVMSILNLWR TWSLKLLKEK ARIVVPKGAF LLGCVDELGI LRGHSIPTEG
     SKTNDVNKLP QIFVRIPDPK RRGQYVTVEG VCIVGRNPSL HPGDIRVVQA VNVPQLNYLT
     NVVVFPSTGD RDVPSMLSGG DLDGDDFFVI WDEKLIPPEW NHRPMPCNVS QSTEHPKEFG
     TPELQMFFVK YLRGDILPVI AHAHLAWADA CGAKSNNCLK LAQLHSKAVD YAKSGEPADM
     PPSLHPKKWP HFMEKKRGAS YRSTRPLGVI YDRVQRVEFS PLYTKPMHKG ILERPCAEKD
     LAFARKIKGD YDIEMRRLMG QFEVDTEFEM WTTFVLSKPR IGTGYKMQER IGKEMGSLRR
     IFRDICIEET GGPGTFETMA DLVVAMYKVT HEEITEALSN LGDAVPTPKN MPLMSFPWLF
     AEWLCKLTLK KDRANNAFPL SISMAAKLRV NMKQRRPLDE ASMGLSDEEG DSELEESILS
     RDSTGSLPAV SDSGIYGEKP VLALTDSSQL PGTISQLPSL GSGLKQIARL SGHDAQLEPL
     GATKDTSETK QLSYTTSSVS CVQITPVPEV NLMDDECVYL CEKYPVLPTG GVSLTPVLVP
     MKRKDANPNL TGPLDDSITI TPLSKKYGTG ASQEQAPSSV EEGREVPTID RVVAIPERTK
     KPAWQRWMES EGLL
//