ID A0A151GRP5_9HYPO Unreviewed; 1493 AA.
AC A0A151GRP5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN ORFNames=DCS_00928 {ECO:0000313|EMBL:KYK59794.1};
OS Drechmeria coniospora.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Drechmeria.
OX NCBI_TaxID=98403 {ECO:0000313|EMBL:KYK59794.1, ECO:0000313|Proteomes:UP000076580};
RN [1] {ECO:0000313|EMBL:KYK59794.1, ECO:0000313|Proteomes:UP000076580}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 6962 {ECO:0000313|EMBL:KYK59794.1,
RC ECO:0000313|Proteomes:UP000076580};
RX PubMed=26975455; DOI=10.1038/srep23122;
RA Zhang L., Zhou Z., Guo Q., Fokkens L., Miskei M., Pocsi I., Zhang W.,
RA Chen M., Wang L., Sun Y., Donzelli B.G., Gibson D.M., Nelson D.R.,
RA Luo J.G., Rep M., Liu H., Yang S., Wang J., Krasnoff S.B., Xu Y.,
RA Molnar I., Lin M.;
RT "Insights into Adaptations to a Near-Obligate Nematode Endoparasitic
RT Lifestyle from the Finished Genome of Drechmeria coniospora.";
RL Sci. Rep. 6:23122-23122(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC ECO:0000256|RuleBase:RU363098};
CC -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC ECO:0000256|RuleBase:RU363098}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYK59794.1}.
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DR EMBL; LAYC01000001; KYK59794.1; -; Genomic_DNA.
DR STRING; 98403.A0A151GRP5; -.
DR InParanoid; A0A151GRP5; -.
DR OrthoDB; 5477883at2759; -.
DR Proteomes; UP000076580; Chromosome 01.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR PANTHER; PTHR23079:SF55; RNA-DIRECTED RNA POLYMERASE; 1.
DR Pfam; PF05183; RdRP; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW Reference proteome {ECO:0000313|Proteomes:UP000076580};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000256|RuleBase:RU363098};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 54..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1292..1321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1359..1387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..138
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1493 AA; 166784 MW; BC016588084B254B CRC64;
MLVLPNGTCH RRHLAPSLPS PLPFNLPSPS ISPPLPSPLP FDLVRLIFPL PASQMAASSR
PPSAPVSPST CRHPRKLHSL RSPGMTCSGP PPSVKSPTDK HQGRLRTASP NHGHGKRPSK
PPGSPSTSRP PPKKPSPPGR AEWAEWRQLT LRLDNLPLDV TMGHLWSWFS SEGTIVWMDM
QDAAKGTRGT MSARIRFEPP PRRAFWAAGT IVVWHPDVRN YPGGLFLRAS VSQEGSRGWF
VSGSAPHQRR YPVKMTAPLR QLDFGTLVAP AAMMVIKSLR PCSAPGVDME LELDVGHRRL
TVRFPVDTKS KDGEGVRQFC FRVDLSSVKR MHQSTEGGNA IWILPLSRPP HYYWKVEDVA
STFGDDDRAW SSGDLWFRAT DIVRDADAPM KHPVAVHSDI DDPGRIDIGR WTAFRLVLEA
HPTRGRVESP DLLLSALEDF NVSVRRCADF ELRPPGPSVW HYLNHPPIPR GHPASALLEL
SAAPVIHLAF EVRYQLEVCV SRGILNEYTM TPGFLRKLAA LETLDATRRL EFLVDQNEAV
HDPMELFTHA DAEAYMPNLR IPHYCAVVRK VVVTPTAVRC NSPTVETSNR VMRKYNHIQD
RFLRVQFIEE AEQGRIAINR KQSDDIWKRI LRTLYQGIRI GDRVYEFLGF GSSQLRQCGV
YFYCPTEHTS CDDIRRWMGE FTHIRVVAKY AARLGQCFST TREIRGIFEP SVKTIADVER
DGHCFTDGVG KISPFLASLI IEEMTLDVFD EPTAFQFRMG GCKGVLTVSP DAQGMEVHVR
RSQEKFKAAT NCLEVIRCAK CSTATLNRQT ITILECLGVP VGAFQRLLDR QIREYQQAMR
SNAVAVGLLT KFVDENQSTL ILAELLKAGF RTDDLQEPFA LNLLNLWRSW SLKLLKEKAR
IQVEESAFVI GCVDETGTLR GHSAATEGSP AKDVDRLPQI FLQLTDPARR HDGTVTVEGT
CIVGRNPSLH PGDIRVVQAV DCPELRHLKD VVVFPSKGDR PVPNMLSGGD LDGDDFFVIW
DPTLMPREWN FPPMSYALSK PLTLSRDVEV NDIRDFFVKY LKNDVLPLIA TSHLALCDEF
PDGPKSQTCR CSHGRAASRP LLTRRRAGLH LAELHSKAVD YPKTGDPADW NTKLQPKRWP
HFMEKKNSYR SKRALGVIYD KVVKQTIQFL PDWEHAFDQR ITGRFELDDG MLEEARRIKR
QYDMAVRRIL TQHDVETEFE LYTGWAMSRP AIGSDYKRQE DLGREYDALK SRFRDMCYEA
AGGSGVKTME RFVAAMYTVT EQEIKIALLE HHGGASDDGG KHEHGKGGGG REGNGRGPRH
ELKAKSMPLI SFPWIFHRIM IRIATGDGQK PTKSLLAAAQ RKTRGAASMP SPGPASGEVP
GRAAAPPPAR DGCADAYAGC AFLDVDDLLG FPVVDDGGEK LGATHVDDGE DLLELEEQGC
DDEGLMTQSR EDISFDDDSE LDKVEEVEVE AEEGESGPAM DRLAALLGFD DDD
//
