ID   A0A165JKD4_9BASI        Unreviewed;      1114 AA.
AC   A0A165JKD4;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE            EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN   ORFNames=CALCODRAFT_303732 {ECO:0000313|EMBL:KZT61949.1};
OS   Calocera cornea HHB12733.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Dacrymycetes;
OC   Dacrymycetales; Dacrymycetaceae; Calocera.
OX   NCBI_TaxID=1353952 {ECO:0000313|EMBL:KZT61949.1, ECO:0000313|Proteomes:UP000076842};
RN   [1] {ECO:0000313|EMBL:KZT61949.1, ECO:0000313|Proteomes:UP000076842}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HHB12733 {ECO:0000313|EMBL:KZT61949.1,
RC   ECO:0000313|Proteomes:UP000076842};
RX   PubMed=26659563; DOI=10.1093/molbev/msv337;
RA   Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA   Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA   Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA   Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT   "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT   Insights into the Origins of Lignocellulose Decay Capabilities.";
RL   Mol. Biol. Evol. 33:959-970(2016).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC         ECO:0000256|RuleBase:RU363098};
CC   -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC       ECO:0000256|RuleBase:RU363098}.
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DR   EMBL; KV423919; KZT61949.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A165JKD4; -.
DR   STRING; 1353952.A0A165JKD4; -.
DR   InParanoid; A0A165JKD4; -.
DR   OrthoDB; 2735303at2759; -.
DR   Proteomes; UP000076842; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR   InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR   PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   PANTHER; PTHR23079:SF14; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   Pfam; PF05183; RdRP; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076842};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000256|RuleBase:RU363098};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
FT   REGION          1..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1114 AA;  124702 MW;  9EB553F0033592F2 CRC64;
     MNQPNDASCT ATETSPSHLE DAHRHVSTRP LPEQTPPKTD ENMTKAAKRR KTSTPSFDRA
     SATDSNARNT HGHAEEHPEP PAAPRAEAPA GRPISKYFIL AHDREAVQQF DENKVPFGIQ
     WELARLQVLR GMSWKNVCHT VTTAIHDKRL DGSCANDGPK LPSLLPKPES KAKSWKKETP
     VLQAAFANER SVREAWSVLD EEQNVTAGAR DGLDGSELEP DVFHGKAHFL ALVEWKNTKP
     EIHLQPPQLG PSTRLARRFG SRRFIRMKDN GTAALEKRMA FYLQKFVFMG RVYRAFFERE
     GTVHLVETNE NYDGRKPDKH QGDHYRLPFF RFIDWHNPMQ LNTDQTMTKW ASRFALALST
     TVPGVRILPE NVHFIRDEIS MAHTGPGKPA SQHQLTDGCG FINGTAMRLI AQQLGWKSTP
     AAIQARFGGA KGMFLLRPEP GESRKALHKV FDFEGPPAIW IRDSQLKIQY GPPDQWDPAM
     LTVDVVKHSY LRCPARLSAE ALVVLADRGV SPSVLIENLR NCVTDEVDSL TGVKSEEPFG
     LRMTMDNGGK TIAERLKRIA IGTARAQGLG DEASDFMDDE EFDQKEDRST AWWRDEISGC
     PSSIEESAMD VLDSGFTLQS CSYLRRKVQR VLEQRLTSVI SRHKISVDSS AQAFAVPCPL
     PGDLLKPGQV CLHMSQCVND PNTGLPTSVI TGPVLLVRHP CKLPTDIQLV EAVACDELRH
     WTDVVITSID RSQPRSLLSK LAGGDYDGDS VSIHWDATLI KGFRNASDEF LEPPSRVEGF
     FKKSTGTVQE FLETGPVTDV QREIEVQEVL LASLRYPGPG LWSTFHDQAV YRWGLKHVTS
     VTLAYIFTTC LDGAKSGLRV EPDVEKAFRA EFARLYPPEW KMAEEIQKPN FKCDPKKRGQ
     VVKEDFIMEQ LRIEGEKLYK EHLDAYVKKC MEIKPEIDPD LAAPWESFKR TGDEIGANSK
     EIIKAEVKAI EKHVKLIWAQ HQEALRRRKD NKDGAEHGFA SLHITTRQDL LRGVSAAFAA
     GPPADTVPFL TSTRQLETVR ASAAYYLDWH LNKDPRNGPA DRGTDFPFTV AMRALCGIKA
     QARGTGTGFK VLTQDTYDAM TLHSRAKKLV VSRA
//