ID A0A166BBW7_DAUCS Unreviewed; 1163 AA.
AC A0A166BBW7;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=DCAR_011374 {ECO:0000313|EMBL:KZN02620.1};
OS Daucus carota subsp. sativus (Carrot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Apiales; Apiaceae; Apioideae; Scandiceae; Daucinae;
OC Daucus; Daucus sect. Daucus.
OX NCBI_TaxID=79200 {ECO:0000313|EMBL:KZN02620.1, ECO:0000313|Proteomes:UP000077755};
RN [1] {ECO:0000313|EMBL:KZN02620.1, ECO:0000313|Proteomes:UP000077755}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DH1 {ECO:0000313|Proteomes:UP000077755};
RC TISSUE=Leaf {ECO:0000313|EMBL:KZN02620.1};
RX PubMed=27158781; DOI=10.1038/ng.3565;
RA Iorizzo M., Ellison S., Senalik D., Zeng P., Satapoomin P., Huang J.,
RA Bowman M., Iovene M., Sanseverino W., Cavagnaro P., Yildiz M.,
RA Macko-Podgorni A., Moranska E., Grzebelus E., Grzebelus D., Ashrafi H.,
RA Zheng Z., Cheng S., Spooner D., Van Deynze A., Simon P.;
RT "A high-quality carrot genome assembly provides new insights into
RT carotenoid accumulation and asterid genome evolution.";
RL Nat. Genet. 48:657-666(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZN02620.1}.
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DR EMBL; LNRQ01000003; KZN02620.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A166BBW7; -.
DR STRING; 79200.A0A166BBW7; -.
DR EnsemblPlants; KZN02620; KZN02620; DCAR_011374.
DR Gramene; KZN02620; KZN02620; DCAR_011374.
DR OMA; LENIDEW; -.
DR Proteomes; UP000077755; Chromosome 3.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd00048; DSRM_SF; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.30.160.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF229; ATP-DEPENDENT RNA HELICASE DHX30; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00035; dsrm; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50137; DS_RBD; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000077755};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 277..444
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 531..705
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1067..1132
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 1048..1069
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1163 AA; 131636 MW; 57821C7DEB1CF7AF CRC64;
MSLIQSRTHF SLRFLFITKP FNLAPTLSFA RPLVSFSKVS STPLRLKRRG NHLSSNYLYK
QSFGYGRYAY EEYDSGLESD RDSQSSKQLG ASTLDNVEEW KWKLSMLIRK KDEQEVISRE
KKDRRDFQQI SALAARMGLC SQQYSKVIVI SKVPLPNYRS DLDDRRPQRE VILPYGLEEE
LVAQLKKYIV KKSTNKEFVL DNAISRSSTV GNLASNQQIY EQEEPIKRTS PGAERILQRR
SLEILNKQQS WQNSLEGQKM QEFRKTLPAY KERGSLLNLV AQNQVVVVSG ETGCGKTTQL
PQYILESEVE ANRGAACSII CTQPRRISAM SVAERVAAER GENLGESVGY KVRLEGMKGR
DTRLLFCTTG ILLRRLLVDR MLKGVTHVIV DEIHERGMNE DFLLIVLKDL LPRRPELRLI
LMSATLNAEL FSSYFGGAPM IHIPGFTYPV RSHFLENILE MTGYRLTTDN QIDNYGQDKM
WKMQKQALRK RKSQIASAVE DTLEAFDLRE YSLRTRDSLS CWNPDSIGFN LIEHVLCHIC
RKERPGAVLV FMTGWDDINS LKGQLQAHPL LGDPSKVLLL GCHGSMDSTE QRLIFNKPEE
GIRKIVLATN MAETSITIND VVFVVDCGKA KETSYDALNN TPCLLPTWIS KASARQRRGR
AGRVQSGECF HLYPRCVHDS FADYQLPELL RTPLQSLCLQ IKSLQLGSIS EFLSRALQAP
EPLSVQNAIE YLKTIGALDE YENLTVLGQK LSVLPVEPKL GKMLILGAIF NCLNPIMTVV
AGLSVRDPFL MPFDRRDLAE ASKAQFSSRD FSDHLALIRA YEGWKNAEKR QAGHDYCWKN
FLSLQTLRAI DSLRKQFFYL LKDTGLVDDV DKCNSWSHDE HLIRAITCAG LYPGICSVVN
KDKSISLKTM EDGPVLLHSN SVNAQQPKIP YPWLVFNEKV KVNSVMLRDS TAVCDSMVLL
FGGSLSRGGL DGHLKMLGGY LEFFMKPGLA ETYLRLRKEL EELIQNKLLN PKLDINDHNE
LLSAVRLVVS DDRCDGKFVY GRHLPSPSKK ELKKQSKGTL TVGGGDNAKN NLQTVLSRAG
HEPPTYKTKQ LKNNKFRSIV MFNGLDFVGQ PCTSKKSAEK DAASEALQWL IGENQPSQKT
VDHMSTILKK SKRTQELHPA RWR
//
